Metabolite Profiling of Phytomedicine or Nutraceutical Products using Ftir-lcd Method
Researchers:
Prof Zhari Ismail
Prof. Mohd Noor Ahmad
Chew Oon Sim
Mohammad Razak Hamdan
Quality control and standarization of herbal and other natural products are the fundamental step towards developing and modernizing such products into evidence based medicines. As herbal medicines is a complex system of mixtures, the plant source conditions of growth and harvest time will undoubtedly affect the presence and concentration of the bioactive constituents, thus affecting the quality and efficacy of phyto medicine/neutraceutical products (phytoproduct)
Infrared spectroscopy technique in combination with chemometrics data procession could provide total metabolite fingerprint profile of the phytoproduct. Thus an innovative ICD (Identification Classification and Discrimination) tool for quality inspection of phytoproduct was developed.
The innovation has the following features and benefits:
- Powerful identification, classification and discrimination (ICD) tool
Benefit: Enable simultaneous assignation of the unknown into its own sample category and specification.
- Speed of analysis for rapid and objective decision making process
Benefit: Enable on-site inspection of raw materials/final products for “ACCEPT” or “REJECT” classification of the materials
- Simple, cost effective and easily accessible analytical instrumentation
Benefit: Only moderate technical expertise is needed for executing the whole testing procedure.
Note: Quality control begins at the cultivation/harvesting stage
For more information, contact
Prof Zhari Ismail
School of Pharmaceutical Sciences
Universiti Sains Malaysia
(Contact details available to registered journalists)
