Are you a biomedical researcher motivated to pursue an outstanding career in cancer research with a focus on organoid research? Cancer will affect more than 1 in 3 Singaporeans. At the Cancer Science Institute (CSI), our mission is to be at the global forefront of research to overcome this scourge. Our innovative international faculty, cutting-edge facilities, supportive working environment and competitive package together enable each of our staff to realize their maximum potential. We now seek a Research Scientist/ Fellow to join the team of Prof. Ashok Venkitaraman. This is an exciting opportunity to work closely with a world-leading cancer researcher to undertake pioneering research on the role of genome instability in human carcinogenesis (eg., see Venkitaraman Science (2014) PMID:24675954 and Venkitaraman DNA Repair (2019) PMID:31337537). The role will provide expertise in the establishment, genetic manipulation and maintenance of human and murine organoid cultures as well as design/ perform and analyse work within the project parameters.
Duties And Responsibilities
Research:
o develop hypotheses and conceptualise, design and execute experiments to address the hypothesis
o to establish, engineer (e.g. by CRISPR) and maintain 3D organoid cultures from a variety of tissue systems
o to carry out molecular and cell biology experiments (i.e. cloning, FACS, western blotting, RNA, sequencing, microscopy) and perform analysis and determinations
o to organise, preserve and present the results of the experiments in a logical manner
o to properly and systematically record all experiments that have been assigned and their results
o to assist in supervising, training and guiding attachment/undergraduate students where required
Please apply here.