PNAS

News

02 Sep 2021
Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences how a protein molecular motor can chop off a piece of cell membrane. The constrict-and-cut mechanism resembles that of a ratchet motor, and is of importance in processes mediating the entry of particles into cells.
Arabidopsis plants used in one of the experiments during the study (Photo by Takeo Sato).
28 May 2021
Scientists from Japan, Europe and the USA have described a pathway leading to the accelerated flowering of plants in low-nitrogen soils. These findings could eventually lead to increases in agricultural production.
24 Feb 2021
A research team from the School of Life Sciences at The Chinese University of Hong Kong (CUHK) has recently discovered that SOX9 protein is an essential regulatory factor of choroid plexus function that ensures the correct composition of cerebrospinal fluid (CSF). The finding, recently published in the prestigious scientific journal Proceedings of the National Academy of Sciences of the United States of America (PNAS), has provided the scientific community a novel understanding to the molecular regulatory mechanisms behind the function of the blood-CSF barrier and lays the groundwork for developing novel therapeutic strategies for preventing and treating neurodevelopmental disorders.
16 Dec 2020
Daegu Gyeongbuk Institute of Science and Technology (DGIST) researchers gain deeper insight into a cell membrane channel, with potential implications for drug development.
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has presented the whole-genome sequence and analyses of the endangered whale shark (Rhincodon typus), the largest extant fish on Earth.
19 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has identified a new metabolic pathway, in which microorganisms utilize single carbon (C1) gases (CO and CO2) as a feedstock.
The anomalies and criticality of liquid water
29 Oct 2020
Scientists at The University of Tokyo use a two-state model based on the formation of tetrahedral structures to explain water’s anomalous properties and the surprising liquid–liquid transition of water.
28 Sep 2020
Researchers from the University of Tsukuba demonstrate that the hypnotic and teratogenic effects of thalidomide are separable. Thalidomide is a medication with several different effects, one of which is promoting sleep in the context of insomnia. In a new study, researchers from the University of Tsukuba have discovered that thalidomide exerts its hypnotic effects through mechanisms distinct from those for the drug’s notorious teratogenicity. These are striking results showing how thalidomide induces sleep independently of its known effects on the teratogenic cereblon pathway. These findings could be helpful in developing novel thalidomide-like hypnotic drugs without thalidomide’s teratogenic effects. The study was published in the scientific journal Proceedings of the National Academy of Sciences of the United States of America.
Phosphate accumulates in high concentrations in intermediate water in the entire subpolar Pacific region
07 Aug 2020
A group of researchers from three Japanese universities has discovered why the western subarctic Pacific Ocean, which accounts for only 6 percent of the world’s oceans, produces an estimated 26 percent of the world’s marine resources.
11 Nov 2019
International collaboration is finding new ways to improve how scientists develop and test models to forecast dengue infection.
City University of Hong Kong, CityU, SaCas9-HF,CRISPR-Cas9
01 Nov 2019
A team of researchers from City University of Hong Kong (CityU) and Karolinska Institutet has recently developed a new protein which can help increase the targeting accuracy in the genome editing process. It is believed that it would be useful for future gene therapies in human which require high precision.
21 Oct 2019
A group of neurons called the corticobasal ganglia projecting neurons are important for vocal learning in young birds, but not in adult birds, according to a study published in the journal Proceedings of the National Academy of Sciences (PNAS).
06 Sep 2019
A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has identified the sleep-promoting effects of dietary threonine, as well as its neurobiological principle.
22 Aug 2019
New microscopy technique provides unprecedented insight into nanoscopic slip layers formed in flowing complex liquids.
Professor Kyung-Tai Min and Soyeon Lee
16 Aug 2019
The protein that revives injured nerve cells was discovered. It is expected to present a new direction in the development of therapeutic agents for regenerating damaged brain or spinal cord nerves.
05 Aug 2019
Two known gene mutations induce pathways that enhance pancreatic cancer’s ability to invade tissues and evade the immune system. Researchers report the molecular details of this process providing insights into druggable targets for immunotherapies.
Envelope protein
08 Feb 2019
Computational models reveal possible weak spots in the HIV surface protein, identifying new targets for drug and vaccine design.
Figure
07 Jan 2019
Korean researchers have clarified the fundamentals of coiled toxin protein which causes neurodegenerative brain disorders. The result is expected to speed the development of treatment for neurodegenerative disorder.
22 Nov 2018
For the first time since its inception, Singaporean researchers were not listed.
Cell survival under different pretreatment conditions.
25 Oct 2018
The innate immune system may be able to be trained to react to viral infections more efficiently by repeated exposure to anti-viral signaling molecules.
Researchers
24 Oct 2018
Korean researchers have identified the interactions of the combinants among calcium channel proteins that exist in nerve and heart cells. The result opened a new path of developing treatments for high blood pressure and brain diseases.
image
09 Oct 2018
Professor Richard Bernhart Owen of the HKBU Department of Geography has analysed African lake sedimentary cores and established connections between a drying climate and technological and evolutionary changes in early humans.
Professor Dong Woog Lee
18 Sep 2018
A team of researchers, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has identified variables that control the cavity-filling rates, required for liquids to penetrate into the cavities.
Underwater photos showing the shift from temperate communities dominated by macroalgae beds (kelp and fucoids) (left), to the transitory cohabitation with tropical corals (middle), to coral reefs (right).
20 Aug 2018
Climate change and other external forces are causing rapid marine community shifts in Japan’s coastal ecosystems. Better understanding of species distribution dynamics, as driven by these factors, can improve conservation efforts and climate change management.
14 May 2018
Big data shows that large marine vertebrates move differently, but consistently, through coastal and ocean waters.
photo 1
04 Apr 2018
A research team led by scientists from the Hong Kong University of Science and Technology (HKUST) has identified new Alzheimer’s disease (AD) genetic risk factors in the Chinese population.
Fitness landscape of HIV envelope protein
26 Feb 2018
An international multi-disciplinary research team led by scientists at HKUST has discovered for the first time a computational framework that could map out the fitness landscape of a crucial protein in the HIV, potentially paving the way for rational design of a vaccine that may force the deadly virus to mutate into forms that lead to its demise.
Image Name
01 Jan 2018
Synchrotron study reveals oxygen’s influence on the chemistry that surrounds us.
25 Oct 2017
A student from South Korea's Ulsan National Institute of Science and Technology (UNIST) was given the 2017 AMOREPACIFIC Great Global Next Generation Research Award.

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