JAMA Internal Medicine

By conducting the world’s first randomized clinical trial, researchers have demonstrated that, while overall survival rates remained comparable in this initial phase, TEE-guided precision CPR enhances end-tidal CO2 levels (indicating better CPR quality and forward blood flow), transforming traditional "blind" compressions into a data-driven science. This groundbreaking research published in JAMA Internal Medicine paves the way for individually customized resuscitation—challenging global standards to maximize survival for millions worldwide.