JCI Insight

RNases have been proposed as a treatment against systemic autoimmune diseases. Researchers from Osaka University showed that RNases have a dual action. In some cases, RNases are detrimental and stimulate the immune response by promoting the binding of antibodies to their targets. These findings will improve the understanding and treatment of systemic autoimmune disorders.

Faulty signalling pathway causes the heart to develop unnaturally while in the embryo stage, according to Duke-NUS Medical School researchers.