Metabolism
About Metabolism
Metabolism promotes excellence in research by publishing high-quality original research, as well as reviews, editorials and commentaries, related to all aspects of human metabolism.
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News
27 Jun 2022
The University of Osaka
Researchers from Osaka University have found that infection with SARS-CoV-2 activates the expression of IRF1, a key regulator of insulin/IGF signaling in multiple tissues, leading to disruption of blood sugar metabolism and, in some cases, new onset of diabetes. Treating infected cells with hormonal factors that decreased IRF1 expression enhanced insulin/IGF signaling, suggesting that this approach could be used to mitigate some of the more severe side effects of COVID-19 in the future.