Proceedings of the National Academy of Sciences

A collaborative research group has shown that biological neurons can be trained to perform a temporal pattern learning task that was previously carried out by artificial systems

Researchers from The University of Osaka have found that potassium KCNQ2/3 channels in the brain, which are important for suppressing cell excitability, need to be fully functional to be trafficked to the appropriate part within the nerve cell and work properly. This link between channel functionality and localization may have important consequences for the development of therapies against KCNQ2/3-related epilepsy.

- Professor Ko Jae-won’s research team at DGIST uncovers key role in signal transmission between neurons and memory formation - Establishing the molecular foundation of learning and memory, expected to treat dysfunctional brain disorders, such as autism and dementia

Researchers from The University of Osaka in collaboration with Baylor College of Medicine have developed a new therapy for a severe form of male infertility called non-obstructive azoospermia (NOA). Using lipid nanoparticles (LNPs) to deliver specific mRNA into the testes of infertile mice, they were able to restart sperm production. The sperm produced were then used in intracytoplasmic sperm injection (ICSI) to successfully generate healthy and fertile offspring. The findings provide a crucial proof-of-concept for treating male infertility caused by genetic defects.