Proceedings of the National Academy of Sciences of the United States of America
09 Feb 2021
Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages. However, detailed analysis in vivo is difficult, so the molecular mechanisms underlying the stemness of gastric tissue stem cells have remained a mystery. Here, by using organoids that mimic tissue structure and function in vivo and GeCKO screening to inactivate arbitrary genes, Alk, Bclaf3 and Prkra have been identified as genes regulating stemness.
16 Jul 2020
A research led by the Department of Geography at Hong Kong Baptist University (HKBU) has revealed that the observed average moving speed (or translation speed) of tropical cyclones making landfall over the coast of China dropped by 11% between 1961 and 2017. These slow-moving tropical cyclones brought about 20% more local total rainfall on average when compared with fast-moving ones, resulting in greater flood risks in the region.
23 Dec 2019
NUS researchers found that chevron patterns in fish swimming muscles require physical forces to correctly develop, not only from genetic instruction or biochemical pathways.
22 Nov 2019
A new study has discovered meteorites containing RNA sugar, ribose, and other bio-important sugars; the first direct evidence of bio-essential sugars' delivery from space to the Earth.
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