Biotech

News

14 Mar 2023
In a study recently published in the journal ACS Nano, published by American Chemical Society, researchers from Kanazawa University, Kanazawa, Japan, collaborating with University of Washington, Seattle, USA, used frequency modulated atomic force microscopy to reveal the molecular architecture of a genetically designed peptide and its self-organization that forms single-molecule thick crystals on atomically flat graphite surfaces, that offer a potential platform for hybrid technologies such as bioelectronics, biosensors, and protein arrays.
red light streaks
04 Mar 2023
Scientists have shown that swarming molecular robots can deliver cargo five times more efficiently than a robot working on its own.
Band-aid with electric streaks
03 Mar 2023
Researchers are working to overcome challenges in order to bring wearable, electric, wound-healing devices to clinical practice.
Hiroshima University Yasufumi Yamada bat ears direction detection research
02 Mar 2023
Bioengineers formulated a mathematical model that clarified the importance of bat ear motions in direction detection, making way for lean, mean sonar navigation machines.
19 Jan 2023
Imagine if your t-shirt could take your sweat and analyze it for health abnormalities. Well, this is much closer to reality after a recent breakthrough by a research group led by a Tohoku University assistant professor. The group created the first microelectronic fiber with microscopic parameters that is capable of analyzing electrolytes and metabolites in sweat.
Red perilla cultivar Hoko-3
11 Jan 2023
A team of Japanese researchers created a high-quality genome assembly of red perilla, a step toward harnessing the plant’s potentially useful bioactive chemicals — and its medicinal properties.
Aspergillus aculeatus
10 Jan 2023
An Osaka Metropolitan University research team analyzed the regulatory mechanisms of carbohydrate-hydrolyzing enzyme production in Aspergillus aculeatus, a filamentous fungus that produces enzymes with an excellent ability to degrade plant biomass. The team found that UDP-glucose 4-epimerase (Uge5), an enzyme known for its involvement in galactose metabolism, also regulates the expression of degrading enzyme genes in A. aculeatus. This is the very first report of Uge5’s roles in selective gene expression in response to different types of inducing sugars in filamentous fungi.
The sphaerimicin analogs (SPMs) inhibit the activity of MraY, and hence the replication of bacteria, with different degrees of effectiveness. The potency of the analog increases as the IC50 decreases (Takeshi Nakaya, et al. Nature Communications. December 20, 2022).
20 Dec 2022
Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.
Micrometre-scale multicompartmental structures of aquabots
15 Dec 2022
A research team led by the University of Hong Kong (HKU) and Lawrence Berkeley National Laboratory has invented an all-water robotic system that resolves the constraints of bio-inspired robots through revolutionary scientific advances.
14 Dec 2022
- Discovery of potential treatment target networks for gene dysregulation uniquely found in patients with autism spectrum disorder - Published in ‘Molecular Psychiatry,’ an international journal of molecular psychiatry
12 Dec 2022
Revelations about the mechanisms of two key proteins which maintain the asymmetric distribution of cholesterol within the cell membrane could help understand and treat diseases linked to its imbalance
01 Dec 2022
Research led by Hong Kong Baptist University (HKBU) involving the use of a pioneering female sterility technique has led to a breakthrough in the production of hybrid rice seeds. Compared to the commonly used “three-line” male sterility technique in hybrid rice seeds production, the novel approach enhances the efficiency of hybrid rice production by eliminating rice seeds that have been produced due to the self-pollination of the “restorer line”. The novel technique enables fully automatic harvesting of hybrid seeds by machines, which can substantially reduce harvesting costs.
11 Nov 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a bioinspired tiny jumping robot, evidence of gender stereotypes in young children, and the first sighting of a new species of crab.
02 Nov 2022
The biofabricated vascular models will pave the way for drug development and deeper understanding of cardiovascular diseases.
Cancer immunity induction system
31 Oct 2022
A research group at Osaka Metropolitan University has developed a drug delivery system that activates a strong cellular immune response to attack cancer cells, using one-tenth of the amount of antigen needed in the group’s previous work. By incorporating positively charged cationic lipids into liposomes and adding negatively charged pH-responsive polysaccharides to the surface, the research group increased the uptake efficiency of liposomes encapsulating cancer antigens by dendritic cells by approximately five times, which increased cytokine production by about 100 times. This increased M1-type macrophages, which activate cancer immunity, and decreased M2-type macrophages, which promote cancer growth.
25 Oct 2022
Small neighboring galaxy filled with dark matter detected with gamma rays, How a virus induces heart inflammation, Shedding light on the happy hormone, Microfossils may hold key evolution clues. Read all in the October's Editor's Choice plus Upcoming event KNOWLEDGE MARKETPLACE – Bangkok 2022: Exchanging of ideas for a Democratic Myanmar.
 Integrated tactile sensors of various sizes were demonstrated. Electrical and mechanical properties were excellent and implementing complex circuits in combination with various sensors appears possible.
27 Sep 2022
- A research team led by Professor Lee Sungwon from DGIST succeeded in developing the world’s first mesh (nanomesh) structured electronic skin device (organic field-effect transistor) - An electronic skin device comprising only a mesh (nanomesh) structure that can measure and process bio-signals for a prolonged period indicates a big step toward integrated systems for electronic skin devices.
20 Sep 2022
A research group led by the Institute of Industrial Science, The University of Tokyo, finds that sensory neurons in human skin modulate melanocytes via the secretion of Repulsive Guidance Molecule B
16 Sep 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the best way to calm a crying baby, technology to sot sex in bovine semen, and a prosthesis for breast cancer patients made from an aquatic plant.
12 Sep 2022
Researchers at The University of Tokyo create a geometric representation of thermodynamic systems and apply it to self-replicating processes, which may help improve our understanding of the physical constraints of living organisms
IMAGE
23 Aug 2022
Two new approaches could help scientists use existing sequencing technology to better-distinguish RNA changes that affect how their genetic code is read.
10 Aug 2022
- DGIST Professor Seo Dae-ha's team developed a super-resolution microscopy that can observe 3D rotational motion of endosomes using gold nanoparticles - By understanding cell transport more accurately through the observation of minute 3D rotation in intracellular transport, it is expected to develop into a disease diagnosis technology.
10 Aug 2022
- Joint research team of DGIST Professor Um Ji-won and Professor Ko Jae-won discovered several SLITRK2 synaptic adhesion gene mutations related to intellectual disabilities - Identified the abnormal pattern in the signaling mechanism of SLITRK2 and presented a new therapeutic biomarker
10 Aug 2022
- DGIST Professor Park Sang-Hyun's research team developed a deep learning technology that accurately detects cancer sites with little information through joint research with a research team led by Professor Nam Su-jeong and Professor Ko Hyeon-Jeong of Seoul Asan Medical Center - Expected to make significant contribution to enhancing the efficiency of deep learning models, which needed an accurately drawn dataset to detect cancer sites.
10 Aug 2022
- DGIST Professor Seo Dae-ha's team developed an experimental strategy to control and observe the chemical reaction of a single nanocatalyst using an optical microscope - Expected to contribute to catalyst design based on accurate understanding of the photocatalytic reaction through an analysis method that helps understanding the electron excitation phenomenon and transition path.
10 Aug 2022
- Developed technology to accurately inspect the quality of red blood cells stored for a certain period of time with AI-based holography technology - Possible to inject clean, healthy red blood cells into the patient. Expected to help minimize side effects of blood transfusion after surgery.
05 Aug 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a treasure map for tracking ant biodiversity, tattoo ink that can monitor your health, and a newly discovered super-Earth.
20 Jul 2022
Researchers at the Institute of Industrial Science at The University of Tokyo introduce a machine learning method to help predict past infection from receptor sequences of immune T-cells even when little data is available, which may help improve human health and our understanding of adaptive immunity
EditorsChoiceHeader
22 Jun 2022
New dinosaur species used claws to graze along the coast, More accurate rainfall predictions, Magnetism helps futuristic cell research, Do compression garments facilitate muscle recovery? Science journalism and why it matters for democracy and our Image of the month. Read all in the June's Editor's Choice and this month's Asia Research News 2022 magazine pick - Lessons from the dead.
21 Jun 2022
A machine rapidly and robustly separates cancer cells from blood samples, overcoming challenges with currently available techniques.

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Giants in history

Pakistani botanist Azra Quraishi (22 September 1945 – 22 November 2002) is recognised for developing virus-free seed potatoes that increased potato production in Pakistan by an estimated five per cent.
Indian botanist Shipra Guha-Mukherjee (13 July 1938 – 15 September 2007) made a breakthrough discovery that enabled the genetic study of plants and, by extension, the development of improved varieties of rice, wheat, potatoes, and other crops.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Filipina chemist María Orosa (29 November 1892–13 February 1945) fought malnutrition and food insecurity in the Philippines by devising over 700 culinary creations including Soyalac, a nutrient rich drink made from soybeans, and Darak, rice cookies packed with Vitamin B1, which could prevent beriberi disease caused by Vitamin B1 deficiency. She was also a partisan of the guerrilla movement resisting Japanese occupation during World War II, and died after being struck by shrapnel while working in her laboratory during the Battle of Manila.
Chinese biochemist Cao Tianqin (5 December 1920 – 8 January 1995) discovered the myosin light chain, a subunit of myosin, a protein crucial for muscle contraction.
In 1939, biochemist Kamala Sohonie (18 June 1911 – 28 June 1998) became the first woman to be accepted into the Indian Institute of Science (IISc).
Chinese agronomist Yuan Longping (7 September 1930 – 22 May 2021) developed the first varieties of the high-yield, hybrid rice that brought food security to multiple countries including China, which had been ravaged by food shortages as recently as the mid-20th century.
David T. Wong (born 1936) is a Hong Kong-born American neuroscientist who is best known for discovering the antidepressant drug fluoxetine, better known as Prozac.
Cyril Andrew Ponnamperuma (16 October 1923 – 20 December 1994) was a Sri Lankan chemist who was interested in the origins of life on Earth. His research in chemical evolution showed how inanimate molecules may have given rise to the building blocks of life – a process known as abiogenesis.
Osamu Shimomura (27 August 1928 – 19 October 2018) was a Japanese organic chemist and marine biologist who dedicated his career to understanding how organisms emitted light.
Janaki Ammal Edavalath Kakkat (4 November 1897 – 7 February 1984) was an Indian botanist who studied plant chromosomes and genetics.
Gopalasamudram Narayanan Ramachandran (8 October 1922 – 7 April 2001) is best known for developing the Ramachandran plot to understand the structure of short chains of amino acids, known as peptides.
Hsien Wu (24 November 1893 – 8 August 1959) is widely regarded as the founder of biochemistry and nutrition science in China. He was the first to propose that protein denaturation was caused by the unfolding of the protein, instead of chemical alteration.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Maqsudul Alam (14 December 1954 – 20 December 2014) was a biologist from Bangladesh who is renowned for his research on genome sequencing
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Gloria Lim (1930-2022) was a mycologist from Singapore who studied tropical fungi. One of the first students to attend University of Malaya when it was founded in 1949, she went on to become the first female Dean of the Faculty of Science at the University of Singapore.