EMBO Molecular Medicine

- Professor Jaewon Ko’s research group has found the mechanism by which a MDGA1 gene mutation induces autism symptoms only in male mice. - Restoring broken brain circuits with female hormone modulating drugs ... Proposing a new treatment strategy for autism

· Microbes affect pathways in the brain that regulate our anxiety levels. · Microbe secreting metabolites—indoles—alleviate anxiety levels. · Indigenous microbes producing indoles open avenues for an alternative treatment therapy using probiotic microbes producing indoles to reduce anxiety attacks—thus a vision of next generation therapy to combat mental health disorders.

New research from Duke-NUS Medical School, and the Agency for Science, Technology and Research identifies chemotherapy-resistant cancers’ escape mechanism, which offers new anti-cancer treatment options.