Light:Science&Applications

Researchers at The University of Osaka and collaborating institutions have developed a cryo-optical microscopy technique that rapidly freezes live cells with millisecond precision during optical imaging. This enables detailed quantitative imaging of fast cellular events via optical microscopy techniques, including super-resolution fluorescence and Raman microscopy. With near-instant immobilization, a single time point in the cells can then be visualized with multiple imaging techniques, providing new insights across cell biology, biophysics, and medical research.