Peer Reviewed

An Osaka Metropolitan University-led research team used hourly precipitation data from 1981 to 2020 and spatial modeling to predict extreme precipitation events for the next 100 years in Japan.

Biochemical and structural biological analysis of a hypothetical gene (protein) within a gene cluster related to metabolic pathway of L-threonate, a four-carbon sugar acid, revealed it’s enzyme function as a L-threonate 3-dehydrogenase and physiological role for metabolic diversity. Although the existence of this enzyme itself was reported in the same academic journal in 1964, the molecular identity of which has remained unknown for over 60 years.

- The brain continues to grow even after adolescence ... according to collaborative research by DGIST and Yonsei University - Demonstrated proactive maturation of the thalamic reticular nucleus against the circuit stalemate theory after the critical period - Opened new frontiers for autism, ADHD treatment, and cognitive rehabilitation with synaptic adhesion protein LRRTM3 as a key switch in high-resolution sensory transduction

Researchers from The University of Osaka have developed a mouse model for achondroplasia. The model identified the importance of a signaling molecule called FGFR3 and a pathway called CREB in regulating bone growth. This pathway is also at least partially responsible for the pathology associated with achondroplasia and impaired bone growth. Their findings advance our understanding of the process of bone growth and provide novel therapeutic targets for achondroplasia.

A single atom can make all the difference. Researchers at Tohoku University have shown that subtle changes in the nitrogen coordination around cobalt dramatically reshape oxygen reduction reaction performance, a cornerstone process for fuel cells and clean chemical production. These insights provide a powerful blueprint for designing next-generation single-atom catalysts to accelerate the transition to sustainable energy.

Glutamine transporter inhibition has been found to suppress cell growth

A recent study co-led by CityUHK found that strong El Niño events cause deeper, longer-lasting harm to human health than previously understood—by slowing long-term improvements in mortality rates for many years, shortening life expectancy, and generating major economic costs.

We all want cheap, long-lasting, green, and efficient energy. Researchers are helping to make this dream a reality with a new distortion-resistant material that greatly improves these aspects of a battery’s cathode.

Duke-NUS scientists have identified how a small number of overactive genes may drive widespread changes in brain function in Down syndrome, helping explain how an extra chromosome affects learning and memory.

The indigenous Bugkalot people of Nueva Ecija call it “kelli” but science has only now been able to identify it as a distinct species and given it a formal scientific name

In our recent JACS paper, we demonstrate that AI-designed ubiquitin-fold proteins achieve extraordinary stability not by tightening their hydrophobic cores, but by reorganizing surface charges to program a structured hydration shell. Using solution NMR and molecular dynamics simulations, we decode this “hydration shield” as a sequence-encoded and engineerable mechanism for extreme protein resilience.

- DGIST Professor Minyoung Song’s team develops a low-power digital IR-UWB transmitter that maximizes spectrum utilization while complying with global spectrum regulations - Achieves 9 times higher area efficiency than before, with expectations for communications and high-precision localization applications with the core technology of next-generation low-power wireless systems

More thorough testing of methane and ethane emissions in Osaka, Japan, identified numerous natural gas-related large methane sources that were mostly overlooked in current predictions. These sources may be useful future targets for mitigating emissions.

Cleaner fish interacted with a mirror in their tank in a way that suggests ‘contingency testing’ intelligence, a higher form of smarts typically found in mammals. This finding coupled with faster self-recognition than previously thought, expands our image of intelligence in these social fish.

Storing hydrogen efficiently is still challenging. Researchers at Tohoku University have developed a new catalyst that coordinates the two key steps of hydrogen formation in alkaline water electrolysis, helping the reaction run more smoothly. A promising step toward practical green hydrogen.

- Selective production of CO and CH₄ achieved by tuning Fe·Cu single-atom–TiO₂ interactions - CO₂ reduction activity enhanced by 55 times (CO) and 44 times (CH₄) compared to conventional TiO₂ - Findings published in Advanced Science

Researchers at The University of Osaka have developed a method to reproducibly form subnanometer pores within a solid-state nanopore. A voltage-driven chemical reaction produces a precipitate that fills and closes the nanopore, while dissolution reopens conductive pathways. This process forms many subnanometer-sized pores, whose effective size can be tuned by changing reactant composition and pH. These ultrasmall pores mimic biological ion channels and enable studies of ion transport in confined spaces.

Researchers at The University of Osaka have created highly transparent wood without plastic additives and revealed that its clarity depends on structural direction. Alkali treatment softens cellulose-based cell walls, allowing internal cavities to collapse during drying and reduce light scattering. Tangential sections become more transparent than radial ones due to anisotropic swelling and densification. The findings offer new design principles for sustainable transparent materials in buildings and advanced devices.

Rehabilitation on weekends and public holidays may improve post-surgery recovery for hip fractures

To further the development of 6G wireless communication systems, we need to develop antennas that can dynamically adapt to ever-changing signal environments. Researchers from Tohoku University and the University of Surrey have recently developed an innovative pattern-reconfigurable Yagi–Uda antenna integrated with a magnetic gear. The new design enables precise beam scanning while avoiding many of the drawbacks that have limited conventional reconfigurable antenna technologies.

Imagine a “smart fluid” whose internal structure can be rearranged just by changing temperature. In a new study in Matter, researchers report a way to overcome a long-standing limitation in a class of “smart fluids” called nematic liquid crystal microcolloids, allowing for reconfigurable self-assembly of micrometer-sized particles dispersed in a nematic liquid crystal host.

DNA - the blueprint of life – can also act as a reaction vessel that guides chemical reactions. This is possible using interstrand crosslinking technology developed by researchers at Tohoku University.

An international collaborative research team, including researchers from the Faculty of Frontier Engineering at Kanazawa University, has for the first time elucidated sex differences in motor unit firing patterns in patients with Parkinson's disease. Utilizing high-density surface electromyography (HD-SEMG), their detailed analysis of motor unit activity revealed that female patients exhibited significantly greater asymmetry in motor unit discharge rates and lower persistent inward currents (PICs) compared to males. These findings suggest that neurodegeneration may be more asymmetrical in females, even when presenting with similar motor symptoms. This study indicates that motor unit behavior can serve as a sensitive evaluation tool to highlight differences in disease presentation between sexes, potentially leading to the development of personalized treatment strategies that consider sex-specific factors in the future.

New research examines how carceral punishment in Philippine jails extends far beyond legal sentences by permeating every bodily sense.

Research from The University of Osaka highlights a new model of a gyroscopic wave energy converter. The device was shown to be capable of absorbing up to half of incoming wave energy across a wide range of frequencies, meaning it could achieve the theoretical maximum efficiency. These results provide important design insights for more efficient and adaptable wave energy technologies.

Researchers look into how people view themselves, nature and the relationships between them to investigate how traditional worldviews and human-nature relationships can impact the health of the Earth

Researchers from the Institute of Industrial Science, The University of Tokyo track the global circulation of water molecules in time and space using isotope ensemble modeling, enabling better prediction of changing hydrological patterns and weather extremes

A study finds that shelterbelts, trees planted as windbreaks, in Japan’s wet farmlands boost edge-dwelling bird population but cut grassland species by about 74%, with numbers rebounding roughly a kilometer away, revealing an overlooked conservation trade-off.

Offers a promising route for precise glass manufacturing

Specific types of malocclusion, or bite misalignment, are associated with tooth loss. A group of researchers recently investigated the effects of anterior crossbite and anterior open bite on tooth loss using one of the largest community-based cohorts, the Tohoku Medical Megabank Cohort Study (2013–2017). The study determined that anterior crossbite increases the risk of tooth and molar loss compared to adults with normal occlusion.