ACS Biomaterials Science & Engineering

Guiding cell growth and shape in three dimensions offers a new approach to mimicking dynamic biological tissues

YNU researchers have developed a method to fabricate complex oriented tissues with multiple directionality using fluidic devices and 3D-printing.

Researchers from Osaka University developed a cell-friendly means of bioprinting at high fidelity. By successive injection of a cell-based ink and a printing support, the ink solidified into defined geometries, even into the shape of a human nose. Printed cells remained viable for at least two weeks. This work is an important milestone toward developing lab-grown tissues and organs, and eventually advancing regenerative medicine as well as animal-free drug safety testing.