Alimentary Pharmacology & Therapeutics

About Alimentary Pharmacology & Therapeutics

Alimentary Pharmacology & Therapeutics is a global pharmacology journal concerned with the effects of drugs on the human gastrointestinal and hepato-biliary systems, publishing a diverse range of topics in the space often with immediate clinical impact to our readership.

News

Hepatitis B virus RNA (HBV RNS) predicts hepatocellular carcinoma (HCC) despite viral suppression. Serum HBV RNA levels at viral suppression predict HCC development in nucleos(t)ide analogue-treated patients with chronic hepatitis B, outperforming HBV core-related antigen (HBcrAg) alone. (Adapted from Kumada et al., Alimentary Pharmacology & Therapeutics, December 2, 2025)
02 Mar 2026
Hiroshima University
Researchers at Hiroshima University and Gifu Kyoritsu University identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.
05 Jun 2024
The University of Osaka
Osaka University researchers discovered a correlation between high GDF15 levels in steatotic liver patients and increased liver cancer risk. Steatotic liver disease cases, fueled by lifestyle-related issues, have surged globally, with Japan reporting a significant prevalence. Elevated GDF15 levels also signify complication risks associated with liver cirrhosis. Combining GDF15 levels and FIB-4 index aids efficient liver cancer detection, potentially improving prognosis through early intervention.