Molecular Cancer

National Taiwan University research team uses single-cell analysis to reveal how exhausted T cells drive immunotherapy resistance and identify a potential new therapeutic strategy.

Cancer metastasis is a major cause of cancer-related death. A research team at City University of Hong Kong (CityU) recently identified a protein that triggers the migration of liver and pancreatic cancer cells and metastasis, and is correlated with shortening the survival time of patients. The research findings were verified by in vitro and in vivo models, supported with clinical data, and are expected to provide a new potential target for cancer therapy.