Nature Protocols

Gel-based sample pre-fractionation leads to detailed proteoform analysis with mass spectrometry

In situ observation and recording of important liquid-phase electrochemical reactions in energy devices is crucial for the advancement of energy science. A research team led by a scholar from City University of Hong Kong (CityU) recently developed a novel, tiny device to hold liquid specimens for transmission electron microscopy (TEM) observation, opening the door to directly visualizing and recording complex electrochemical reactions at nanoscale in real-time at high resolution. The research team believes that this innovative method will shed light on strategies for fabricating a powerful research tool for uncovering the mysteries of electrochemical processes in the future.

Two-dimensional (2D) transition metal dichalcogenides (TMDs), an emerging class of materials that can be used as semiconductors and insulators, have promising potential in various applications due to their unique properties. But the reliable production of these atomically thin 2D materials has been challenging. A research team led by a material scientist from City University of Hong Kong (CityU) has developed an efficient electrochemical exfoliation method to achieve high-yield production of TMD nanosheets. This new strategy lays a new direction for mass production of TMD nanosheets for wide application in future.

High-resolution genome structural analyses combined with large-scale simulations show the arrangements of the genome’s spool-like structures affecting gene expression.