Proceedings of the National Academy of Sciences of the United States of America (PNAS)
News
01 Jan 2024
Researchers from Osaka University have shown that a protein called HKDC1 is a new target of another protein, TFEB, and plays key roles in maintaining the stability of both mitochondria and lysosomes. HKDC1 is essential for mitophagy to remove damaged mitochondria, and mediates mitochondria–lysosome contact, which is critical for lysosomal repair. The role of HKDC1 in maintaining the stability of these organelles counteracts cellular senescence, revealing HKDC1 as a potential therapeutic target for age-related diseases.
Events
Sorry, no events coming up for this topic.
Researchers
Sorry, no researchers coming up for this topic.
Giants in history
Sorry, no researchers coming up for this topic.