Journal of the American College of Cardiology
About Journal of the American College of Cardiology
JACC publishes peer-reviewed articles highlighting all aspects of cardiovascular disease, including original clinical studies, experimental investigations with clear clinical relevance, state-of-the-art papers and viewpoints.
- Website: https://www.jacc.org/journal/jacc
- Current Issue: https://www.jacc.org/toc/jacc/current
News
27 May 2024
Duke-NUS Medical School
• International study, led by researchers in Singapore and Germany, unveils unexpected mechanisms of SGLT2 inhibitors, challenging the assumption that their beneficial, organ-protective effects stem from a diuretic effect.
• Insights suggest the drugs, which have been developed to treat diabetes but are meanwhile widely used for chronic kidney disease and heart failure, trigger ancient and highly conserved evolutionary survival signals that may also contribute to longer healthspans.