Peer Reviewed

Researchers at Tohoku University have achieved a significant breakthrough in the synthesis of carbon nanotubes, also known as the “king of nanomaterials.”

Researchers from Osaka University have discovered that GPR31, found in certain immune cells in the human gut, plays a key role in responding to bacterial metabolites and activating immune responses. Specifically, in the presence of metabolite pyruvate, these cells extend dendrites to sample the gut environment, detect pathogens, and activate T cells through GPR31. This discovery could inform the development of new drugs, vaccines, and probiotics that enhance gut immunity by targeting this pathway.

Researchers from Osaka University have revealed a close link between polyploidy and DNA damage, showing that the presence of DNA damage increases the likelihood of polyploidization occurring, and that polyploid cells are more likely to accumulate DNA damage. However, polyploid cells can also tolerate higher levels of DNA damage, taking longer to enter damage-induced growth arrest and senescence. This discovery will aid the development of novel therapies for certain drug-resistant cancers originating from polyploid cells.

Researchers from Osaka University have demonstrated that ultra-short, high-dose proton irradiation increases cell survival rates even in normoxic conditions, challenging prior assumptions that this effect only occurs in hypoxic environments. This world-first discovery utilizes a new superconducting AVF cyclotron, enabling the application of the "FLASH effect," which minimizes damage to healthy tissues while maintaining local control of the tumor. This breakthrough is expected to lead to a new cancer treatment, FLASH proton therapy, offering fewer side effects and higher tumor control.

Taiwan's New Public Health Preventive Medicine Strategy Achieves Success After 10 Years

An international team of neuroscientists showed for the first time that modifying a protein that controls cell growth can reactivate dormant neural stem cells in fruit flies, offering new hope in the fight against neurological diseases.

Pathogenic system found on plasmid can lead to severe food poisoning symptoms

Researchers in Tokyo find that a 100-year-old method for redirecting water can be used to control heat dissipation in electronics

The study’s findings highlight the urgent need for comprehensive regulation, including a potential ban on flavored tobacco products and the adoption of plain packaging to curb their appeal.

Photoswitching and thermal switching properties allow writing by irradiation or heat and erasing by visible light

The equatorial Pacific plays a crucial role in regulating tropical cloud formation and regional weather extremes, earning it the nickname “the pacemaker of global warming.” Though its impact may seem subtle, this oceanic region has been a silent hero, slowing the pace of global warming. Now, climate scientists are on a quest to discover whether this protective mechanism will continue to pulsate in our favor.

Not much is known about the extent of Hepatitis A virus (HAV) contamination among Philippine communities, according to researchers, prompting an urgent call for further research and monitoring efforts.

A multi-institutional research team led by SUTD has developed a novel method that uses titanium resin to fabricate high-resolution 3D photonic crystals with a complete photonic bandgap in the visible range—a feat that has eluded scientists for decades.

To enhance the life quality of patients with sleep disordered breathing, researchers and clinicians led by an SUTD scientist used computational modelling to design custom-fit masks that have improved positive airway pressure treatment.

Scientists visualize and control magnetic domains in quantum antiferromagnets

An organic catalyst offers chemists precise control over a vital step in activating hydrocarbons.

Fluorescein angiography capable of assessing neural blood flow in chronic nerve compression neuropathy

Fungi don’t have eyes or a brain, but their intelligent behaviours may surprise you! Research at Tohoku University suggests that fungi may be able to recognize shapes.

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

An unprecedented rapid increase in anthropogenic fingerprints around 1952 in the global strata reflects the point in time when humanity began to overwhelm the Earth system

Surgery for discoid lateral meniscus in adolescence could lead to worsening complications and difficult solutions

Unearthing new LEDs, solar cells, and photodetectors requires extensive knowledge surrounding the optical properties of materials. Calculating these takes time and resources. Yet researchers from Tohoku University and the Massachusetts Institute of Technology have unveiled a new AI tool that can accurately, and crucially much faster than quantum simulations, for predicting optical properties.

Researchers from Osaka University have created a high-performance polymer that can be chemically recycled without compromising its heat and chemical resistance. The revolutionary design includes a directing group that allows links in the polymer to be broken easily with a catalyst and the original polymer to be reformed in few steps. The directing group could be included in many polymers, potentially providing a new generation of high-performance plastics that can be recycled indefinitely.

Researchers at Tohoku University developed a novel method using facet-selective, ultrafine cocatalysts to efficiently split water to create hydrogen – a clean source of fuel.

A team of scientists in Singapore and the US uncovered how a protein that controls our biological clock modifies its own function, offering new ways for treating jet lag and seasonal adjustments

Successful selection of compounds inhibiting the function of a transcription factor

Researchers performed two studies to better characterize the effects of job embeddedness, or factors that influence an employee’s commitment to their job, on voluntary turnover in the face of job insecurity.

Future of bioplastics made from carbon dioxide and biomass molecules could rely on more enzymes, shorter incubation periods

A study underscores the importance of taking into account local peoples’ everyday experiences, practices, and perceptions in establishing water quality.

How multiple DNA binding proteins compete for the DNA substrate leads to different biochemical outcomes. Using single-molecule experiments, this work demonstrates that the regulatory protein Mei5-Sae3 complex stabilizes Dmc1 recombinases on RPA-coated DNA, leading to efficient RPA displacement and Dmc1 assembly, which in turn stimulates recombination progression.