Associate Prof. Masanori Sakaguchi

We have three major research focuses:
1. Function of sleep in memory and its relation to pathology
2. Roles of adult-born neurons in memory consolidation during sleep
3. Dynamic change of consciousness and its mechanisms

Biography

1995Apr – 2001Mar Medical school, Univ. Tsukuba
2001Apr – 2005Mar Student, Dept. Physio., Sch. Med., Keio Univ.
PhD candidate, Univ. Tsukuba
2005Apr – 2007Mar Assistant Prof., Dept. Physio., Sch. Med., Keio Univ.
2007Apr – 2009Mar Postdoc, Hospital for Sick Children, Univ. Toronto, Canada
2009Apr – 2010Sep PD for overseas research, JSPS
2010Oct – 2011Mar Postdoc, Brain Science Institute, RIKEN/td>
2011Apr – 2013Jan Special Postdoc Fellow(SPD), RIKEN
2013Apr - Associate Prof. of International Institute for Integrative Sleep medicine, University of Tsukuba

Major achievements

Purple R*, Sakurai T, Sakaguchi M*, Auditory conditioned stimulus presentation during NREM sleep impairs fear memory in mice, Sci. Rep., 7:46247, 2017 Apr, *=corresponding authors,  DOI: 10.1038/srep46247.

Fujinaka A¥, Li R¥, Hayashi M, Kumar D, Changarathil G, Naito K, Miki K, Nishiyama T, Lazarus M, Sakurai T, Kee N, Nakajima S, Wang SH, Sakaguchi M*, Effect of context exposure after fear learning on memory generalization in mice, Mol. Brain, 2016 Jan, 9:2, *=corresponding author, ¥=equal contribution, both undergraduates, DOI: 10.1186/s13041-015-0184-0.学長表彰受賞

Sakaguchi M*, Kim K, Yu LMY, Hashikawa Y, Sekine Y, Okumura Y, Kawano M, Hayashi M, Kumar D, Boyden ES, McHugh TJ, Hayashi Y*, Inhibiting the activity of CA1 hippocampal neurons prevents the recall of contextual fear memory in inducible ArchT transgenic mice, Plos ONE, 2015 Jun, 10(6): e0130163. *=corresponding authors