Internal medicine Rheumatology

News

05 Apr 2023
Researchers from Osaka University found that the COMMD3/8 complex is implicated in the progression of the autoimmune response in a mouse model of rheumatoid arthritis. They identified celastrol, the active compound of a medicinal herb, as an inhibitor of the COMMD3/8 complex. Celastrol blocked the progression of rheumatoid arthritis. Thus, celastrol is a potential lead for developing treatments against rheumatoid arthritis.

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Young scientist from Kulgam,  Kashmir.
Dr Ashfaq Ahmad Shah ('اشفاک'), born on 6 June 1992, from South Kashmir, Dodarkoot (ددیرکوٹ), Kulgam, Jammu and Kashmir, India, is the microbiologist/immunologist whose broad area of specialisation incorporates infection immunity. He served as a researcher at the Graphic Era (Deemed to be) University, Dehradun, UK, India, from 2020 to 2025. Currently he is working as a scientist and assistant professor at the University Centre for Research and Development at Chandigarh University. As a microbiology scientist, Dr Shah has pursued novel dimensions of infection immunity pertaining to the correlation and impact of elicitation-triggered phytoalexins and phytoanticipins on the benign immune system of human beings. This parameter of immunology is termed 'phytoalexin-immunomodulation scrutiny' in the contemporary era. Dr Shah's research encompasses a range of areas, including the investigation of anti-inflammatory and antimicrobial compounds; evaluation of antibiotic resistance; study of immunomodulatory activities; disease model studies; protease isolation against specific protein antigens; study of novel compounds via the hyphenated techniques of GCMS, HPLC, FTIR-MS, etc.; and the disciplines of Medicine and kalology, including tyrosinase inhibition, PPO inhibition, skin whitening agents, kerato-peeling, etc. Dr Ashfaq is a scientist, doctoral researcher, reviewer, and editorial member of several journals and books of national and international repute. He has contributed extensively to scientific literature by publishing his research in journals of national and international repute. So far he has published more than forty infection/immunology/pharmacology scientific papers in Scopus and SCIE-indexed journals, including two international books. In recognition of his contributions, Dr Shah received the Young Scientist Award in August 2023 for his groundbreaking academic performance in the field of infection immunity. Dr Shah has also been an active editor of Wikipedia pages in the field of medical science since 2015, with more than 1000 edits in medical topics available to medical literature worldwide. Dr Shah has also submitted his NGS work, like nucleotide sequences of mutated genes, to the gene banks like the National Library of Medicine (NCBI) USA.gov.

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