iScience

New research using genome editing technology has allowed scientists to create a model and assess a gene mutation associated with neuropsychiatric disorders in humans. The study has revealed how the mutation functions in the brain and affects anxiety and sociality.

Tohoku University scientists in Japan have developed a virus-based approach for measuring variations in gene regulatory elements, called transcription factors, as conditions change in live organisms.

A Japanese research team created a new way to sort living cells suspended in fluid using an all-in-one operation in a lab-on-chip that required only 30 minutes for the entire separation process.

A new study on nematode worms reveals physical contact with objects can help prevent neuromuscular decline in simulated microgravity. The research provides new insights into maintaining human health in space.

Researchers from The University of Tokyo develop a novel device for the safe and effective transplantation of human induced pluripotent stem cell (iPSC)-derived pancreatic beta-cells in type I diabetes mellitus

Cells replicate their genetic material and divide into two identical clones to perpetuate life. Some cells pause in the process with a single, undivided nucleus. When the cell resumes division after such a pause, the nucleus can become caught in the fissure, splitting violently, and killing both cells. But that is not always the case. Researchers from Hiroshima University in Japan are starting to understand how active nuclear displacement rescues cell death.

Malaria parasites transform healthy red blood cells into rigid versions of themselves that clump together, hindering the transportation of oxygen. The infectious disease affects more than 200 million people across the world and causes nearly half a million deaths every year, according to the World Health Organization’s 2018 report on malaria. Until now, however, researchers did not have a strong understanding of how the parasite so effectively infiltrated a system’s red blood cells.

A team of researchers has developed a system that produces electricity and hydrogen (H2) while eliminating carbon dioxide (CO2).