Assoc.Prof. Ganesh Pandian Namasivayam

Prof. Ganesh Pandian Namasivayam's research goal is to create "Smart Genetic Switches" that precisely ON and OFF the genetic and epigenetic factor(s) of interest.


Ph.D in Applied Biosciences, Niigata University (2009)

MSc in Biotechnology, University of Madras, India (2002)

BSc in Biochemistry, University of Madras, India (2000)



Visiting Scientist, AO Research Institute, Switzerland

Visiting Professor, KiBum Lab, Rutgers University, USA

Scientific Advisor, ReguGene Co. Ltd.



 TEDx TEDx Kyoto University Speaker (2018)

 8th World Congress on Targeting Mitochondria Research Excellence Keynote Speaker (2017)

 Brilliant Publishing Organization Rising Star Award-Science (2017)

 Department of Biotechnology Program, DG Vaishnav College Scientist of the Month (2016)

 iCeMS Kyoto University Make a Project Award (2015)

 Royal Society of Chemistry (RSC) Biomaterials Poster Award - 1st Rank (2013)

iCeMS Kyoto University Cross-disciplinary research prize (2012)

Heidelberg-Kyoto Joint Symposium -2011 Best Poster Award and Biotechnology Journal Prize (2011)

iCeMS Kyoto University Best Poster and Excellence Award (2010)

AAAS Science Translational Medicine and Days of Molecular Medicine-2011 Young Investigator Award


Selected publications

Targeted elimination of mutated mitochondrial DNA by a multi-functional conjugate capable of sequence-specific adenine alkylation .T. Hidaka, K. Hashiya, T. Bando, Ganesh N. Pandian*  and H. Sugiyama*. CELL Chem. Biol. In Press

Targeted Epigenetic Induction of Mitochondrial Biogenesis Enhances Antitumor Immunity in Mouse Model. M. Malinee, Ganesh N. Pandian*  and H. Sugiyama*. CELL Chem. Biol. In Press Pre-print: SSRN: or

Sequence-specific control of mitochondrial gene transcription using programmable synthetic gene switches called MITO-PIPs. T. Hidaka, H. Sugiyama and Ganesh N. Pandian*. 2021, Methods in Molecular Biology (Clifton, N.J.), 2275, 217-225. In: Weissig V., Edeas M. (eds) Mitochondrial Medicine. Humana, New York, NY.

Designing biomimicking synthetic transcription factors for therapeutic gene modulation.  Ganesh N. Pandian* and H. Sugiyama*. 2021, In: Wang D.O., Packwood D. (eds) Cell-Inspired Materials and Engineering. Fundamental Biomedical Technologies. Springer, Cham.


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