23 Dec 2021
By searching for the protein transglutaminase 1 (TGM1) among patients with various autoimmune skin diseases, researchers have successfully identified a separate disease that can be linked to autoimmunity against TGM1. This backward method demonstrates a new way of identifying autoantigens as markers for various diseases. By letting autoantigens point to the disease, diagnosis and treatment can be facilitated, according to the study now published in PNAS.
30 Nov 2021
Researchers at the Department of Microbiology at The University of Hong Kong have succeeded in the isolation of SARS-CoV-2 Omicron variant from clinical specimens. This is the first known research team in Asia that has succeeded in isolating the Omicron variant. The isolated variant will enable the development and production of vaccines against Omicron, which has been designated as a "variant of concern" by the World Health Organization.
09 Nov 2021
Researchers from DGIST explore the role of symbiotic skin bacteria in wound healing for different fish species
02 Nov 2021
The world’s largest analysis of gastric tumour cells provides a launch pad for scientists to plan more effective therapies.
27 Oct 2021
Giants in History: Maqsudul Alam (14 December 1954 – 20 December 2014) was a biologist from Bangladesh who is renowned for his research on genome sequencing.
27 Oct 2021
Researchers reveal correlation between ribotype (RT) strains of Cutibacterium acnes, which are found in human skin, and the lifespan of the nematode Caenorhabditis elegans. Strains RT4 and 8, which are associated with acne in human skin, shortened the lifespan of the nematode, while RT6, which are predominantly found in healthy human skin, did not. Also, it was found that the healthy skin-related RT6 strain of C. acnes improved C. elegans resistance to the pathogenic organism Staphylococcus aureus.
13 Oct 2021
Coral reefs, comprising some of the most diverse and delicate ecosystems under water, are under immense stress. From global warming to pollution to pathogens, many of the reef-building coral species are listed as threatened or endangered. But, according to researchers in Japan, the corals may have an unlikely ally: bacteria.
11 Oct 2021
A long-standing hypothesis, the dual-structure model, posits that Japanese populations derive dual ancestry from indigenous Jomon hunter-gatherer-fishers and succeeding Yayoi farmers. We conduct paleogenomic analyses of people of the Jomon, Yayoi, and Kofun periods from Japanese archaeological sites. We identify a later influx of East Asian ancestry in the Kofun period and clarify that the genome of the modern Japanese population is composed of three ancestral components, proposing a tripartite model of Japanese origins.
05 Oct 2021
Researchers from DGIST explain how DNA is compacted to a million-times its full length in sperm cell nuclei
15 Sep 2021
New research published in Stem Cell Reports has found elevated cholesterol supply from astrocytes to neurons in the model of Alzheimer's disease (AD) brains, suggesting that modulating brain cholesterol could be explored in the search of treatment options for the devastating, degenerative disease.
13 Sep 2021
iCeMS scientists and colleagues have designed a molecular code that powers up cancer-fighting immune cells.
11 Sep 2021
Giants in History: Chinese agronomist Yuan Longping (7 September 1930 – 22 May 2021) developed the first varieties of the high-yield, hybrid rice that brought food security to multiple countries including China, which had been ravaged by food shortages as recently as the mid-20th century.
10 Sep 2021
Magnetic patterns in meteorites, Treating mitochondrial diseases, underwater sensors and a broad COVID-19 vaccine in the September Editor's Choice. Plus, what's it like to communicate vaccine research in a pandemic and Asia Research News 2022.
26 Aug 2021
A multi-functional, small molecule can tag mutant genetic sequences inside mitochondria for removal.
14 Jul 2021
Researchers have found a way to enhance radiation therapy using novel iodine nanoparticles.
17 Jun 2021
Researchers from Hiroshima University now have a better understanding of the mechanism underlying how certain bacteria can transfer genetic material across taxonomic kingdoms, including to fungi and protists. Their work, published in Frontiers in Microbiology, could have applications in changing how bacteria perform certain functions or react to changes in their environment.
09 Jun 2021
Publication bias, or the tendency of researchers and journals to not publish uninteresting findings, plagues much of the natural sciences and especially biomedical research. Hiroshima University researchers have developed a meta-analytic technique exploiting publicly available transcriptome databases that avoids the problem—and in so doing, discovered four genes previously unknown to be associated with responding to low-oxygen stress.
31 May 2021
High-resolution genome structural analyses combined with large-scale simulations show the arrangements of the genome’s spool-like structures affecting gene expression.
28 May 2021
Scientists from Japan, Europe and the USA have described a pathway leading to the accelerated flowering of plants in low-nitrogen soils. These findings could eventually lead to increases in agricultural production.
21 May 2021
Single-cell gene studies are clarifying the roles of the brain’s specialised immune cell in Alzheimer’s disease and offer new avenues for treatment of this incurable condition.
13 May 2021
A simple tool allows researchers to track how different subpopulations of the Plasmodium knowlesi parasite are changing over time.
13 Apr 2021
The O. swinhoana frog species is the first vertebrate known to retain descendant genes that now determine sex in mammals, birds, and fishes inherited from a common ancestor.
07 Apr 2021
New national body established to further research insights, improve patient outcomes and create new economic opportunities for the biomedical technology industry.
26 Mar 2021
An ‘eat-me’ signal displayed on cell surfaces requires activation of a lipid-scrambling protein by a nuclear protein fragment.
24 Feb 2021
Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited. An international research team, including a biomedical scientist from City University of Hong Kong (CityU), has developed a high-throughput biological assay technique which enabled them to conduct a systematic analysis on the impact of nearly 100,000 genetic variants on the binding of transcription factors to DNA. Their findings provided valuable data for finding key biomarkers of type 2 diabetes for diagnostics and treatments. And they believe that the new technique can be applied to studies of variants associated with other genetic diseases.
17 Feb 2021
Researchers from DGIST have now found a way to keep living, wet cells viable in an ultra-high-vacuum environment, using graphene, allowing—like never before—accurate high-resolution visualization of the undistorted molecular structure and distribution of lipids in cell membranes. This could enhance our bioimaging abilities considerably, improving our understanding of mechanisms underlying complex diseases such as cancers and Alzheimer’s
11 Feb 2021
A brain enzyme activates dormant neural stem cells, revealing how defects in its gene could lead to neurodevelopmental disorders.
04 Feb 2021
Cells replicate their genetic material and divide into two identical clones to perpetuate life. Some cells pause in the process with a single, undivided nucleus. When the cell resumes division after such a pause, the nucleus can become caught in the fissure, splitting violently, and killing both cells. But that is not always the case. Researchers from Hiroshima University in Japan are starting to understand how active nuclear displacement rescues cell death.
23 Dec 2020
A joint research team co-led by City University of Hong Kong (CityU) has developed a novel computational tool that can reconstruct and visualise three-dimensional (3D) shapes and temporal changes of cells, speeding up the analysing process from hundreds of hours by hand to a few hours by computer. Revolutionising the way biologists analyse image data, this tool can advance further studies in developmental and cell biology, such as the growth of cancer cells.
23 Dec 2020
A transporter protein that regulates cell membrane cholesterol likely played an important role in vertebrate evolution, according to a review published by iCeMS researchers in the journal FEBS Letters.
The Khwarizmi International Award (KIA) acknowledges the efforts made by researchers, innovators and inventors from across the globe and to appreciate their high quality research work and contributions to different fields of science and technology.
South Korea's Ulsan National Institute of Science and Technology (UNIST) has organized a grand celebration event in celebration of the 10th anniversary of its opening and 12th anniversary of its establishment on Tuesday, May 12, 2019.
Osaka City University
Takashi Hashimoto's major expertise is clinical and basic research for both autoimmune bullous diseases and hereditary skin diseases.
Daegu Gyeongbuk Institute of Science and Technology (DGIST)
Myungin Baek is currently an Assistant Professor at Daegu Gyeongbuk Institute of Science and Technology (DGIST).
Duke-NUS Medical School
Prof. Patrick Tan's research focuses on developing genomic approaches to unlock the molecular and clinical diversity of gastric cancer (aka stomach cancer)- a leading cause of global cancer mortality.
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
Prof. Ganesh Pandian Namasivayam's research goal is to create "Smart Genetic Switches" that precisely ON and OFF the genetic and epigenetic factor(s) of interest.
Assistant Professor and Head Department of Environmental Science Dr. D. Y. Patil Unitech Society's Dr. D. Y. Patil Arts, Commerce and Science College, Pimpri, Pune 411018
International Islamic University Malaysia (IIUM)
Dr. Tengku Haziyamin Tengku Abdul Hamid's recent discovery of a novel strain has enabled a new patent to be drafted and was awarded gold medal in Malaysian Technology Expo 2021 for his new probiotic prototype called ProAquaVcare.
Dr. Indika, Neluwa-Liyanage is a lecturer at the Faculty of Medical Sciences of University of Sri Jayewardenepura. His research focuses on pathogenesis and metabolic profile of autism spectrum disorder. He has also collaborated actively with international researchers in the field of inherited metabolic disorders.
Universiti Malaysia Sabah
Dr. Connie Cassy Ompok is an early childhood education expert and a Senior Lecturer at the Faculty of Psychology and Education, Universiti Malaysia Sabah. She Started her career in Early Childhood Education as a preschool teacher (2004-2007), a lecturer in early childhood education at the Malaysian Institute of Teacher Education (2008-2016) before serving as a Senior Lecturer in Early Childhood Education at UMS (2016 until now).
Earth-Life Science Institute (ELSI), Tokyo Institute of Technology
Tony Z. Jia is a researcher at Japan’s Earth-Life Science Institute (ELSI), based at the Tokyo Institute of Technology. His research focuses on astrobiology, prebiotic chemistry, and origins of life.
Universiti Malaysia Sarawak
Dr Paul Cliff Simon Divis is the director of Malaria Research Centre at Universiti Malaysia Sarawak (UNIMAS).
I am engaged in the development of a new device for embryo evaluation which measures embryo oxygen consumption and a new medication for infertility. Recently, I focused on causative genes of disorders of sex development and searched pathogenic variants using a whole-genome reference panel constructed by Tohoku Medical Megabank Organization.
Ji-Won Lee is an assistant professor at the Faculty of Dental Medicine at Hokkaido University, Japan,
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
My research background covers multidisciplinary fields such as Pharmaceutics, Cancer Nanomedicine, Bioengineering and Organ-on-a-chip platforms. My current research focuses on the development of dynamic biological barriers on a chip such as blinking human cornea on a chip.
Hidemitsu Kitamura is an associate professor at the Section of Disease Control, the Institute for Genetic Medicine, Hokkaido University, Japan.
Viteroretinal surgeon working on developing treatments for retinal dystrophies and many other retinal diseases.
Dept of Medical Neuroscience, School of Medicine, Kanazawa University
The Chinese University of Hong Kong (CUHK)
Professor, School of Life Sciences, The Chinese University of Hong Kong
Universiti Putra Malaysia (UPM)
Currently Associate Professor at Universiti Putra Malaysia. Holds a PhD from University College of Wales and BSc (Hons) Genetics from the University of Liverpool
Professor and Head of Microbiology and Immunology Department, Faculty of Medicine, Lincoln University College (LUC) Malaysia.