Genetics

News

25 Jan 2023
Researchers from Osaka University have identified a protein, FER1L5, that is essential for sperm to acquire fertilizing ability. Sperm from mice lacking this protein were unable to undergo the “acrosome reaction”, which releases molecules that facilitate fertilization, resulting in impaired male fertility. As FER1L5 is also present in human sperm, this work may lead to new diagnostic methods and treatments for male infertility in humans.
Asia Research News: Editor's choice
20 Jan 2023
Overeating mechanism: why "eating just one chip"🍟 is impossible, Measuring hidden energy of gamma-ray bursts, Marine species that can adapt to ocean acidification & A rough start can lead to a strong bond, Read all in our first Editor's Choice of 2023. Plus our interview on what dengue vaccine approval in EU💉means for global dengue protection.
Red perilla cultivar Hoko-3
11 Jan 2023
A team of Japanese researchers created a high-quality genome assembly of red perilla, a step toward harnessing the plant’s potentially useful bioactive chemicals — and its medicinal properties.
Aspergillus aculeatus
10 Jan 2023
An Osaka Metropolitan University research team analyzed the regulatory mechanisms of carbohydrate-hydrolyzing enzyme production in Aspergillus aculeatus, a filamentous fungus that produces enzymes with an excellent ability to degrade plant biomass. The team found that UDP-glucose 4-epimerase (Uge5), an enzyme known for its involvement in galactose metabolism, also regulates the expression of degrading enzyme genes in A. aculeatus. This is the very first report of Uge5’s roles in selective gene expression in response to different types of inducing sugars in filamentous fungi.
27 Dec 2022
tRNA-MaP can rapidly analyze the specificity of tRNA m1A22 methyltransferase (TrmK) for substrate tRNAs.
23 Dec 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are how a wasp uses its genitals to defend itself, a compound commonly found in mushrooms that could delay cognitive decline, and sunshine as a cure for myopia.
Mechanism by which CREB-Regulated Transcription Coactivator 1 (CRTC1) suppresses overeating
23 Dec 2022
Scientists reveal genetic mechanism associated with high-calorie food-fueled obesity
19 Dec 2022
Researchers from Osaka University have developed a culture system using pluripotent cells from southern and northern white rhinos, which was refined to produce primordial germ cell-like cells (PGCLCs). These cells are the equivalent of primordial germ cells, the origin of eggs and sperm. The study marks an important first step in the potential production of northern white rhino gametes, which could be used in breeding programs, and is the first to induce PGCLCs in a wild animal.
14 Dec 2022
- Identifying the entire genome of the primitive fish, little skate, and proposing the molecular mechanism for the evolution of movement - Joint Research of DGIST · Seoul National University · New York University Medical School... Published in SCI-level journals
12 Dec 2022
Revelations about the mechanisms of two key proteins which maintain the asymmetric distribution of cholesterol within the cell membrane could help understand and treat diseases linked to its imbalance
Scatter plots of CI-score of all genes (2652 genes) identified in this study
11 Dec 2022
Scientists investigate how genes in some insects can influence one another to change their expression depending on environmental conditions.
09 Dec 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a coat that can make you invisible to AI cameras, a fossilized whale skeleton found in a river valley, and hope for humans after our Y chromosome disappears.
01 Dec 2022
Research led by Hong Kong Baptist University (HKBU) involving the use of a pioneering female sterility technique has led to a breakthrough in the production of hybrid rice seeds. Compared to the commonly used “three-line” male sterility technique in hybrid rice seeds production, the novel approach enhances the efficiency of hybrid rice production by eliminating rice seeds that have been produced due to the self-pollination of the “restorer line”. The novel technique enables fully automatic harvesting of hybrid seeds by machines, which can substantially reduce harvesting costs.
Amami spiny rat (Photo: Asato Kuroiwa).
28 Nov 2022
The Sox9 gene is upregulated in the absence of sex-determining Y chromosome and Sry gene in Amami spiny rat.
Tsuneko (1933) and Reiji Okazaki ( 1930 – 1975)
03 Nov 2022
Giants in History: Tsuneko (1933) and Reiji Okazaki ( 1930 – 1975)were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
20 Oct 2022
Giants in History: Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
06 Oct 2022
Giants in History: Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health.
Editor's Choice
29 Sep 2022
Linked lanthanides shine light on crystal engineering, New technique reveals hidden genome, Red, white and blue alerts for dangerous bacteria & Windows gain competitive edge over global warming. Read all in the September's Editor's Choice plus this month's Asia Research News 2022 magazine pick - Floating sensors to gather ocean data.
16 Sep 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the best way to calm a crying baby, technology to sot sex in bovine semen, and a prosthesis for breast cancer patients made from an aquatic plant.
31 Aug 2022
Scientists understand genes related to intellectual disabilities, but are often unsure of how mutations in these genes cause developmental disorders. Now, a research group led by two Tohoku University researchers has uncovered the role of CHAMP1—a gene whose mutations are associated with intellectual disability—in neuronal development.
25 Aug 2022
Thousands of short RNA sequences that code for microproteins and peptides have been identified, opening new avenues for disease research and drug development.
IMAGE
23 Aug 2022
Two new approaches could help scientists use existing sequencing technology to better-distinguish RNA changes that affect how their genetic code is read.
22 Jul 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are 100-million-year old dino footprints found in China, horizontal gene transfer between insects, plants and microbes, and when penguins stopped flying.
Overview of the functional annotation workflow, Fanflow4Insects
22 Jul 2022
Research team develops functional annotation workflow for genome sequencing of insects
08 Jul 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are zero-waste poultry processing that can boost lab-grown meat, residential facilities made for low-gravity environments, and new methods of cloning cells.
06 Jul 2022
Researchers from Osaka University examined how disease severity is evaluated in the context of preimplantation genetic testing for single-gene diseases (PGT-M) by conducting case studies of the regulatory frameworks governing PGT-M in Japan, the United Kingdom, and Western Australia through analysis of relevant policy documents. Results of their study showed that how policies define the standard for disease severity that would justify PGT-M and how decisions are made regarding the eligibility of individual cases have important social and ethical implications.
The house mouse, Mus musculus. (Photo by Toyoyuki Takada)
16 Jun 2022
Scientists have revealed the genetic structure and diversity, and inferred the population history, of the wild house mouse across Europe and Asia.
Experimental approaches
26 Apr 2022
Researchers set out to find new ways to artificially induce mRNA to respond in ways that could eventually lead to therapeutic outcomes, expanding on the success of the mRNA-based COVID-19 vaccines and opening up new possibilities across a host of possible genetic therapies.
IMAGE
25 Apr 2022
Examination of endangered species’ stem cells unveils ancient genetic links between mammals.
Purnima Sinha
07 Apr 2022
Giants in History: Purnima Sinha (12 October 1927 – 11 July 2015), the first Bengali woman to receive a doctorate in physics, analysed clay structures using x-ray equipment that she built from salvaged World War II-era parts.

Events

07 Nov 2022
FCS2022 is jointly organized by eight major research institutes in Singapore and includes a line-up of internationally renowned cancer experts. The conference converges the latest cancer discoveries around the world and promises ground-breaking and innovative insights into cancer research.
The Khwarizmi International Award (KIA) acknowledges the efforts made by researchers, innovators and inventors from across the globe and to appreciate their high quality research work and contributions to different fields of science and technology.
South Korea's Ulsan National Institute of Science and Technology (UNIST) has organized a grand celebration event in celebration of the 10th anniversary of its opening and 12th anniversary of its establishment on Tuesday, May 12, 2019.
28 Aug 2019
The 2019 Genome Expo is scheduled to be held at UNIST from August 28 to 29, 2019.

Researchers

City University of Hong Kong (CityU)
Jian Yan
Dr. Yan is an assistant professor at the Department of Biomedical Sciences, City University of Hong Kong (CityU). His current research focuses on developing genomic tools to dissect lncRNA function and mechanism in diseases and to identify genetic variations that contribute to disease pathogenesis.
Kyoto University
So Iwata
Dr. So Iwata is a Professor at the Graduate School of Medicine Kyoto University and the Group Director of the SACLA Science Research Group, RIKEN SPring-8 Center. He has investigated how specialized membrane channels remove antimicrobial drugs from inside bacterial cells.
Duke-NUS Medical School
Dr. Owen Rackham
Dr Owen Rackham is an expert in the development of computational approaches for cell reprogramming and disease-gene association.
Osaka City University
Takashi Hashimoto's major expertise is clinical and basic research for both autoimmune bullous diseases and hereditary skin diseases.
Universiti Teknologi MARA (UiTM)
Department of Microbiology / Biomolecular Sciences Universiti Teknologi MARA Malaysia
Daegu Gyeongbuk Institute of Science and Technology (DGIST)
Myungin Baek is currently an Assistant Professor at Daegu Gyeongbuk Institute of Science and Technology (DGIST).
Duke-NUS Medical School
Prof. Patrick Tan's research focuses on developing genomic approaches to unlock the molecular and clinical diversity of gastric cancer (aka stomach cancer)- a leading cause of global cancer mortality.
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
Ganesh Pandian Namasivayam
Prof. Ganesh Pandian Namasivayam's research goal is to create "Smart Genetic Switches" that precisely ON and OFF the genetic and epigenetic factor(s) of interest.
Assistant Professor of Environmental Science Krishna Institute of Allied Sciences Krishna Institute of Medical Sciences Deemed To Be University, Karad
International Islamic University Malaysia (IIUM)
Dr. Tengku Haziyamin Tengku Abdul Hamid
Dr. Tengku Haziyamin Tengku Abdul Hamid's recent discovery of a novel strain has enabled a new patent to be drafted and was awarded gold medal in Malaysian Technology Expo 2021 for his new probiotic prototype called ProAquaVcare.
Dr. Indika Neluwa-Liyanage is a lecturer in Biochemistry at the Faculty of Medical Sciences of University of Sri Jayewardenepura. His research focuses on the metabolic alterations underlying autism spectrum disorders and inherited metabolic disorders.
Universiti Malaysia Sabah
Dr. Connie Cassy Ompok is an early childhood education expert and a Senior Lecturer at the Faculty of Psychology and Education, Universiti Malaysia Sabah. She Started her career in Early Childhood Education as a preschool teacher (2004-2007), a lecturer in early childhood education at the Malaysian Institute of Teacher Education (2008-2016) before serving as a Senior Lecturer in Early Childhood Education at UMS (2016 until now).
Earth-Life Science Institute (ELSI), Tokyo Institute of Technology
Tony Z. Jia is a researcher at Japan’s Earth-Life Science Institute (ELSI), based at the Tokyo Institute of Technology. His research focuses on astrobiology, prebiotic chemistry, and origins of life.
Universiti Malaysia Sarawak
Dr Paul Cliff Simon Divis is the director of Malaria Research Centre at Universiti Malaysia Sarawak (UNIMAS).
Tohoku University
I am engaged in the development of a new device for embryo evaluation which measures embryo oxygen consumption and a new medication for infertility. Recently, I focused on causative genes of disorders of sex development and searched pathogenic variants using a whole-genome reference panel constructed by Tohoku Medical Megabank Organization.
Hokkaido University
Ji-Won Lee is an assistant professor at the Faculty of Dental Medicine at Hokkaido University, Japan,
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
My research background covers multidisciplinary fields such as Pharmaceutics, Cancer Nanomedicine, Bioengineering and Organ-on-a-chip platforms. My current research focuses on the development of dynamic biological barriers on a chip such as blinking human cornea on a chip.
Hokkaido University
Hidemitsu Kitamura is an associate professor at the Section of Disease Control, the Institute for Genetic Medicine, Hokkaido University, Japan.
Tohoku University
Viteroretinal surgeon working on developing treatments for retinal dystrophies and many other retinal diseases.
Kanazawa University
Dept of Medical Neuroscience, School of Medicine, Kanazawa University
The Chinese University of Hong Kong (CUHK)
Professor, School of Life Sciences, The Chinese University of Hong Kong
Universiti Putra Malaysia (UPM)
Currently Associate Professor at Universiti Putra Malaysia. Holds a PhD from University College of Wales and BSc (Hons) Genetics from the University of Liverpool
Professor and Head of Microbiology and Immunology Department, Faculty of Medicine, Lincoln University College (LUC) Malaysia.
Professor in Agriculture and Education in the Iloilo Science and Technology University Leon Campus (ISAT U). Leon, ILOILO, PHILIPPINES

Giants in history

Reiji Okazaki (8 October 1930 – 1 August 1975) and Tsuneko (7 June 1933) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Tsuneko (7 June 1933) and Reiji Okazaki (8 October 1930 – 1 August 1975) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
In his over 30 year career in rice research, Munshi Siddique Ahmad (1924 – 19 October 2011) developed more than 30 varieties of high-yielding rice, including the BRRI Shail strain, which was responsible for increasing the rice production of Bangladesh from 8 million tonnes in 1965 to 20 million tonnes in 1975.
Eminent Filipina scientist and educator Clara Lim-Sylianco (18 August 1925 – 23 July 2013) is remembered for her extensive research on mutagens – often-carcinogenic agents that permanently alter genetic materials such as DNA – antimutagens and bioorganic mechanisms.
Motoo Kimura (13 November 1924 – 13 November 1994) was a Japanese theoretical population geneticist who is best remembered for developing the neutral theory of molecular evolution.
Janaki Ammal Edavalath Kakkat (4 November 1897 – 7 February 1984) was an Indian botanist who studied plant chromosomes and genetics.
Maqsudul Alam (14 December 1954 – 20 December 2014) was a biologist from Bangladesh who is renowned for his research on genome sequencing
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Kono Yasui (16 February 1880 – 24 March 1971) was a Japanese botanist who researched the genetics of poppies, corn and spiderworts and surveyed the plants that had been affected by the nuclear fallout after the atomic bombings of Hiroshima and Nagasaki.
Hitoshi Kihara (1893 – 1986) was one of the most famous Japanese geneticists of the 20th century. One of his most significant contributions was identifying sex chromosomes (X and Y) in flowering plants.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.