Genetics

News

A medaka fish from the study. (Photo: Saori Yokoi)
05 Sep 2024
Hokkaido University
Medaka fish that lacked functional Hmgn2 genes were unable to distinguish between simple shapes, revealing a new function for the regulatory gene.
Sterilization of cats and other companion animals, such as by removing the uterus, is a common procedure, with the donated uterus of cats providing the cells to generate feline induced pluripotent stem cells.
04 Sep 2024
Osaka Metropolitan University
Feeder-free induced pluripotent stem cells hold hope in therapies for cats’ chronic kidney disease
Improvement effects of MOD06051. In the glomeruli of the disease group, neutrophils (green) that are positive for the NETs marker citrullinated histone H3 (Cit-H3; red) are observed. Cit-H3 was not observed in neutrophils infiltrating in the low-dose and high-dose treatment groups. (Yuka Nishibata, et al. Nature Communications. August 22, 2024)
22 Aug 2024
Hokkaido University
A newly developed compound that reduces harmful inflammation in rats caused by overactive neutrophils shows great potential as a safer treatment for various inflammatory diseases in humans.
transcriptome meta-analysis workflow-pig and wild boar-chicken and red junglefowl
03 Aug 2024
Hiroshima University
Wild boars and red junglefowl gave rise to common pigs and chickens. These animals’ genes evolved to express themselves differently, leading to signatures of domestication — such as weaker bones and better viral resistance — in pigs and chickens, according to a research team based in Japan.
02 Aug 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are gene transplants that help flies live longer, a COVID-19 treatment using embryonic stem cells, and how a frog named after Darwin likes to get it on.
30 Jul 2024
Applied Microbiology International has announced that it has recruited 11 new Global Ambassadors from around the world.
The resistance mechanism of indisulam by YAP/TAZ activation
30 Jul 2024
Hiroshima University
The anti-tumor drug indisulam has shown promise both in cell cultures and in animal studies. However, clinical trials have shown fewer clear-cut results. Scientists from Hiroshima University Hospital have been researching the reasons behind this resistance to it.
18 Jul 2024
Ehime University
Elucidation of the substrate recognition mechanism of ArcS, the second-step enzyme for archaeosine synthesis in tRNA
12 Jul 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are how diversity in genetics and our microbiome influences our health, and how the shape of ice makes it slippery
07 Jun 2024
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are new biomarkers for fish, quantum theory showing fewer black holes, and how complaining can be beneficial.
Asia Research News Editors Choice
07 Jun 2024
Asia Research News
Blue energy future, Off switch for brain cells, New Japanese lily species, Generative AI in motion, Economies take off with new airports and Braille-shaped electrodes for retinal implants. Read all in the latest Editor's Choice. Plus SciCom Coffee with Catriona Child.
24 May 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are how catching up on sleep in big chunks does not completely pay our sleep debt, a biodegradable paper placed on the brain to help with neurological diseases, and a dinosaur that shows the transition between scales and feathers.
13 May 2024
The University of Osaka
Researchers from Osaka University have used a novel combination of short-read and long-read RNA sequencing to identify the different isoforms of genes expressed in the crustacean Daphnia magna. Males and females are genetically identical, but using this technique the team revealed genes that switch the predominant isoform in a sex-dependent manner. This study contributes to our understanding of Daphnia’s sexual dimorphism and helps further advance technologies in crustacean aquaculture.
08 May 2024
Singapore University of Technology and Design
Using image-based deep learning and dynamic shape classification techniques, SUTD researchers developed a novel method of checking red blood cell deformability that is less invasive, more cost-effective, more sensitive, and has higher throughput.
 The new species of Japanese lily Lilium pacificum
01 May 2024
Osaka Metropolitan University
Classification of these plants bloom to double the number of taxonomic groups through morphological study, DNA analysis
12 Apr 2024
Asia Research News
Zika virus vaccine targets brain cancer, 120-year quest to farm lobsters, Arctic nightlife bursts with sound, Eating a robot, Molecular orientation is key & New treatment for ALS and dementia. Read all in the latest Editor's Choice.
11 Apr 2024
Duke-NUS Medical School
Duke-NUS study reveals why some pancreatic and colorectal tumours resist targeted anti-Wnt drugs and suggests how to overcome it, offering new hope to patients with fully treatment-resistant cancers
Illustration of the body plan of a toothed whale, with a cross section of the head showing the melon (dark yellow) and the extramandibular fat bodies (light yellow) which are key organs for using sound such as echolocation. (Hayate Takeuchi, Takashi Fritz Matsuishi, Takashi Hayakawa. Gene. January 20, 2024)
08 Apr 2024
Hokkaido University
Genetic analysis finds evidence suggesting that acoustic fat bodies in the heads of toothed whales were once the muscles and bone marrow of the jaw.
05 Apr 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are where music affects our bodies, a battery powered by the oxygen inside our bodies, and the largest bird family tree to date.
29 Mar 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are spiders that join together to transform into a flower, birds giving the right of way, and a potential natural treatment for hair loss.
18 Mar 2024
Academia Sinica
Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are neurodegenerative diseases that commonly occur in middle-aged people. FTD is second only to Alzheimer's disease in terms of dementia prevalence. Both ALS and FTD arise from neuronal degeneration through mechanisms that remain unclear. Dr. Yun-Ru (Ruby) Chen's team in the Genomics Research Center (GRC), Academia Sinica recently discovered a new pathological mechanism for neuronal degeneration using synthetic peptides. They also discovered that a disaccharide can increase neuronal survival and reduce degeneration. The result provides therapeutic strategies for future treatment of these neurodegenerative diseases. The study was published in the top international journal "Science Advances" on February 23, 2024.
08 Mar 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the mechanisms behind regrowing limbs and middle-age weight gain, and a new wound dressing combining mussels and silkworms.
05 Mar 2024
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
A novel method for studying genes in testicular cells of living animals could lead to breakthroughs in male contraception and fertility treatments.
IMAGE
28 Feb 2024
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
A new user-friendly tool helps researchers explore how gene activity is influenced by chemical modifications, providing insights into disease and paths to new treatments.
26 Jan 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a closer step towards artificial spider silk, rocks made from plastic, and why a flightless dinosaur developed small wings.
12 Jan 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are how a King Kongesque ape went extinct, how antibodies can make you dizzy, and a material that can break down harmful chemicals using the sun.
4.5SH RNA (green) is located in the nuclear speckles (Srsf1, magenta)—structures in the cell nucleus associated with gene expression—in embryonic stem cells, where it plays an essential role in RNA processing. (Rei Yoshimoto, et al. Molecular Cell. December 13, 2023)
13 Dec 2023
Hokkaido University
A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
03 Nov 2023
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are mouse embryos grown on the International Space Station, a super-efficient micro engine, and how a virus can help deaf children hear.
27 Oct 2023
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are parasites that borrow their hosts genes, how waste feathers can be used in hydrogen fuel cells, and a poor bird that was caught up in a powerful typhoon.
Scheme of safety evaluation by DANGER analysis
23 Oct 2023
Hiroshima University
Risk-averse on/off-target assessment for CRISPR editing without reference genome

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Giants in history

Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Pakistani botanist Azra Quraishi (22 September 1945 – 22 November 2002) is recognised for developing virus-free seed potatoes that increased potato production in Pakistan by an estimated five per cent.
Indian botanist Shipra Guha-Mukherjee (13 July 1938 – 15 September 2007) made a breakthrough discovery that enabled the genetic study of plants and, by extension, the development of improved varieties of rice, wheat, potatoes, and other crops.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Reiji Okazaki (8 October 1930 – 1 August 1975) and Tsuneko (7 June 1933) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.
Hitoshi Kihara (1893 – 1986) was one of the most famous Japanese geneticists of the 20th century. One of his most significant contributions was identifying sex chromosomes (X and Y) in flowering plants.
Kono Yasui (16 February 1880 – 24 March 1971) was a Japanese botanist who researched the genetics of poppies, corn and spiderworts and surveyed the plants that had been affected by the nuclear fallout after the atomic bombings of Hiroshima and Nagasaki.
Maqsudul Alam (14 December 1954 – 20 December 2014) was a biologist from Bangladesh who is renowned for his research on genome sequencing
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Janaki Ammal Edavalath Kakkat (4 November 1897 – 7 February 1984) was an Indian botanist who studied plant chromosomes and genetics.
Motoo Kimura (13 November 1924 – 13 November 1994) was a Japanese theoretical population geneticist who is best remembered for developing the neutral theory of molecular evolution.
Eminent Filipina scientist and educator Clara Lim-Sylianco (18 August 1925 – 23 July 2013) is remembered for her extensive research on mutagens – often-carcinogenic agents that permanently alter genetic materials such as DNA – antimutagens and bioorganic mechanisms.
In his over 30 year career in rice research, Munshi Siddique Ahmad (1924 – 19 October 2011) developed more than 30 varieties of high-yielding rice, including the BRRI Shail strain, which was responsible for increasing the rice production of Bangladesh from 8 million tonnes in 1965 to 20 million tonnes in 1975.
Tsuneko (7 June 1933) and Reiji Okazaki (8 October 1930 – 1 August 1975) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.