Kiyomi Shitaoka

Prof. Kiyomi Shitaoka's research aims to obtain effective antibody genes and T cell receptor genes by single-cell analysis of B cell and T cell receptors on lymphocytes. In addition, to apply these genes to develop new treatments for overcoming infectious diseases and cancer.

Education

Doctor of Medicine (University of Toyama)
Master (Medical Science) (Hiroshima University)

Main work history

Assistant Professor, Immunology, Graduate School of Medical Sciences, Hiroshima University (2020)
Specially Appointed Assistant Professor, Immunology, Department of Medicine, University of Toyama Graduate School of Science (2019)
Visiting Assistant Professor, Advanced Cancer Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama (2017)
Researcher (2011) / Senior Researcher, World Co., Ltd. (since 2014)

Award

Young Researcher Encouragement Award, 20th Japan Cancer Immunology Society, 16F10 Cancer-specific T cell identification and TCR gene therapy trial by single-cell analysis of melanoma-infiltrating lymphocytes (2016)

Selected publications

Relationship between T cell receptor clonotype and PD1 expression of tumor infiltrating lymphocytes in colorectal cancer, European Journal of Immunology

A novel, rapid and efficient method of cloning functional antigen-specific T-cell receptors from single human and mouse T-cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol. 474, No. 4, pp. 709-714

TRAIL-receptor 1 IgM antibodies strongly induce apoptosis in human cancer cells in vitro and in vivo, ONCOIMMUNOLOGY, Vol. 5, No. 5, 2016

Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4 (+) T cells, SCIENCE TRANSLATIONAL MEDICINE, Vol. 7, No. 310

TCR function analysis using a novel system reveals the multiple unconventional tumor-reactive T cells in human breast cancer-infiltrating lymphocytes. Eur. J. Immunol., European Journal of Immunology, 2021 Jun 25.