Medicine

News

22 Sep 2022
A pathway that malfunctions in advanced non-alcoholic fatty liver disease could be fixed with the aid of spermidine, a compound naturally found in bodily cells and certain whole foods.
22 Sep 2022
Scientists have uncovered how Coxsackievirus B3, the most common cause for viral heart inflammation, takes advantage of a specific heart sensor to trigger chronic inflammation that can lead to heart failure.
16 Sep 2022
Osaka University researchers identified the specific protein complex that recognizes when cellular organelles called lysosomes become damaged. When this occurs, the CUL4A protein complex transfers a molecular tag, called polyubiquitin, to a lysosomal protein known as LAMP2. WDFY1, another protein in the complex, is able to recognize and interact with LAMP2. These initial steps are critical to beginning a process called lysophagy, in which these damaged lysosomes are cleared away by the cell.
15 Sep 2022
Cellular structures called mitochondria depend on microproteins to assist and control the assembly of a protein chain that extracts energy from nutrients, according to a new study by scientists in Singapore.
13 Sep 2022
A commentary in Nature Medicine advocates the proper application of artificial intelligence in healthcare and warns of the dangers when machine learning algorithms are misused.
13 Sep 2022
An estimated 1208 excess suicide deaths for men and 1825 for women were recorded during the COVID-19 Pandemic in Japan through December 2021, with the impact being greatest in women and younger age groups.
09 Sep 2022
While the primary site of SARS-CoV-2 infection is in the nose, most antiviral immunity studies have been performed with peripheral blood. T-cell analysis of nasal swab samples suggests getting infected with SARS-CoV-2 following vaccination could confer potentially more robust, nasal-based immunity.
30 Aug 2022
Tohoku University scientists in Japan have made a scaffold that supports the growth of new bone in large jaw defects in mice. Their findings, published in the journal PNAS Nexus, bring scientists one step closer to addressing the issues currently facing the treatment of large jaw bone defects, especially in the elderly.
Editor's Choice
26 Aug 2022
Researchers have made perovskite solar cells more efficient and stable, A new cause of Parkinson's related cell death, Hibernating superpower is in the blood, Common mechanism for cancer and atherosclerosis, COVID-19 antibody skin-based test. Read all in the August's Editor's Choice plus an Interview with Prof Sutee Yoksan on The story behind the new dengue vaccine & this month's Asia Research News 2022 magazine pick - The evolutionary history of puddle frogs.
25 Aug 2022
Giants in History: The first Thai woman to receive a degree in medicine, Margaret Lin Xavier (29 May 1898 – 6 December 1932), is best remembered for her compassion towards her less privileged patients.
Immune Therapies Against Chronic Hepatitis B
25 Aug 2022
Immunity in Chronic Hepatitis B and innovative treatment development
24 Aug 2022
A group of researchers in Thailand has replicated "Hydroxy-xanthones", the vital extracts rich in antioxidants found in mangosteen peels that kill germs and halt infections in the intestinal mucosa. It hopes to expand to include health products for humans and animals in the future.
24 Aug 2022
A study led by researchers from Hong Kong Baptist University (HKBU) has demonstrated that a multifunctional organic compound named F-SLOH has the potential to treat Alzheimer’s disease (AD) at an early stage. The team found that it can inhibit the aggregation of amyloid-beta (Aβ), and reduce the hyperphosphorylation of tau proteins and neuroinflammation in the brain to improve the pathological features of AD. The findings have been published in the international academic journal Redox Biology.
23 Aug 2022
Takeda’s tetravalent dengue vaccine (TAK-003) is now the only dengue vaccine approved in Indonesia for use regardless of previous dengue exposure and without the need for pre-vaccination testing. This approval marks Takeda’s first marketed vaccine outside of Japan.
22 Aug 2022
Researchers led by Osaka University shed light on a metabolic network integrated by an oral microbe Fusobacterium nucleatum (F. nucleatum). Analysis of co-cultures of F. nucleatum with other commensal oral bacteria revealed that metabolic cross-feeding enables F. nucleatum to increase the production of the polyamines putrescine and cadaverine, thereby promoting the development of periodontitis. The nutritional interactions of F. nucleatum may serve as potential targets for the development of new methods to prevent periodontal disease.
19 Aug 2022
Adults self-report their pain on a one to 10 numerical score, while children can point to an equivalent face scale — from a green smiling face to a red crying face — to indicate their pain. Newborns, however, cannot say a number or point to a face, leaving it up to their caregivers to identify and evaluate any pain they may be in. Until the turn of this century, a significant number of clinicians did not recognize that neonates could even experience pain, resulting in infrequent, nonstandard training for medical workers. Now, researchers are reporting that a flexible e-learning program improves neonate pain management knowledge and skills for nurses.
17 Aug 2022
Osaka University researchers used a large dataset of trauma patients in Japan to determine the characteristics and biomarkers most strongly associated with mortality risk by employing machine learning methods. This work may help improve the practice of emergency medicine.
17 Aug 2022
The OWSD Early Career Fellowship is a prestigious award of up to USD 50,000 offered to women who have completed their PhDs in Science, Technology, Engineering and Mathematics (STEM) subjects and are employed at an academic or scientific research institute in one of the listed Science and Technology Lagging Countries (STLCs).
08 Aug 2022
Reaction design framework proposed by computations leads to the discovery of a wealth of reactions, opening new paths for drug development.
05 Aug 2022
Scientists at Duke-NUS Medical School, Singapore, have found that elevated blood levels of an amino acid called homocysteine correlate strongly with the severity of an advanced form of non-alcoholic fatty liver disease. They also found vitamin B12 and folic acid could potentially prevent and/or delay disease progression.
03 Aug 2022
Researchers have discovered that vitamin K acts as a powerful antioxidant. It can inhibit ferroptosis, a type of cell death associated with Alzheimer’s disease and organ damage, by trapping lipid radicals. Furthermore, the team identified the long-sought-after vitamin K-reducing enzyme, the identity of which remained unknown for more than half a century.
31 Jul 2022
The history of extracting chay root dye — a natural red colourant — from the chay plant (Oldenlandia umbellata) dates back to at least the seventeenth century. Read on to know more about the relevance of the dye in the textile dyeing practices of southern India.
29 Jul 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the discovery of an ancient palace that could be connected to Genghis Khan, the joy of letting your mind wander, and a wound dressing made from frog skin that promotes healing.
Editors Choice Header
23 Jul 2022
Researchers create 'time machine' to study ancestor galaxies, Robotics engineers pay attention to matters of the heart, Custom suits for delivery worms, Tough, light structures with superior impact resistance and Virtual training can reduce stress and anxiety. Read all in the July's Editor's Choice plus op-ed: To boost South Korea’s basic science, look to values, not just budgets, this month's Image & Asia Research News 2022 magazine pick - Better memristors for brain-like computing.
22 Jul 2022
The World Health Organization (WHO) welcomes the launch by Gavi, the Vaccine Alliance, of the landmark opportunity for countries to apply for funding to introduce, or further roll-out, the RTS,S/AS01 (RTS,S) malaria vaccine.
22 Jul 2022
Osaka University researchers designed a silicon-based agent that successfully generated hydrogen continuously in the mouse gastrointestinal tract in an ulcerative colitis (UC) model. The hydrogen served as an antioxidant that could eliminate the reactive oxygen species shown to induce the chronic inflammation responsible for the damage and symptoms caused by UC. Mice given the agent had reduced hemorrhage, inflammation, and hyperexcitability in the brain area associated with visceral pain and discomfort. These results may help with the development of a novel treatment for UC.
Hibernation study Japanese black bear
15 Jul 2022
Cultured human skeletal muscle cells infused with serum from hibernating bears exhibited “muscle gain” confirming that these creatures’ ability to avoid muscular damage despite months of inactivity is in their blood.
05 Jul 2022
23 Gold awarded at MTE 2022: COVID-19 International Innovation Awards and Advanced Healthcare & Life Sciences International Innovation Awards
02 Jul 2022
An artificial intelligence (AI) algorithm trained to listen to patients pass urine is able to identify abnormal flows and could be a useful and cost-effective means of monitoring and managing urology patients at home. It is presented today at the European Association of Urology annual congress (EAU22), in Amsterdam.
01 Jul 2022
Specialised physician training, nurse-led motivational conversations and follow-up with patients, and subsidy on combination medication significantly lowered BP among patients with uncontrolled hypertension, according to findings from Singapore.

Events

27 Jul 2022
BIO Asia–Taiwan is Asia's largest biotech networking event, and is jointly organized by the global Biotechnology Innovation Organization (BIO) and the Taiwan Bio Industry Organization (Taiwan BIO).
07 Nov 2022
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
17 Jan 2022
World’s brightest minds converge at virtual summit to inspire young researchers and discuss key issues
01 Nov 2021
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
12 Oct 2021
The Asia's Largest Partnering “BioJapan” will be held both digitally and physically. Meet your potential business partners in this Partnering Event!
07 Oct 2021
The National Healthcare Group (NHG) is proud to present the 19th Edition of the Singapore Health & Biomedical Congress (SHBC).
24 Feb 2021
INTERPHEX Week Osaka is Asia's leading exhibition for pharmaceutical industry, consists of 2 exhibitions for pharmaceutical technologies - INTERPHEX OSAKA (Manufacturing & Packaging) and PharmaLab Expo OSAKA (Pharma R&D and Drug Discovery).
23 Nov 2020
Global health emergencies look set to be a part of our lives. What awaits us in 2021 and what lessons can we draw from COVID-19 coverage? How can we support newsrooms and journalists for more informed and impactful journalism about global scientific, technical and human challenges? What role does journalism play in seeking solutions for a better world that is both healthy, and sustainable?
27 Nov 2020
ACRLS 2020 aims to contribute to strengthening cooperation and relationship among members worldwide and forming a strong global network by providing various benefits to robotic clinics in rapidly growing nations throughout Asia.
25 Nov 2020
Asia's Leading Pharma & Bio Tech Show will be held as scheduled from November 25-27, 2020 at Makuhari Messe, Japan. It will be held both on-site and online.
16 Nov 2020
Optimising Clinical Trials | Commercialising Great Science | Partnering for Growth
02 Nov 2020
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
01 Oct 2020
The 6th annual RNA Biology Symposium jointly organized by the RNA Biology Centre of CSI Singapore (NUS), Skin Research Institute of Singapore (A*STAR), Duke-NUS Medical School, School of Biological Sciences (NTU) and Singapore-MIT Alliance for Research and Technology (SMART)
The Khwarizmi International Award (KIA) acknowledges the efforts made by researchers, innovators and inventors from across the globe and to appreciate their high quality research work and contributions to different fields of science and technology.
26 Jun 2020
Flattening the Curve with Digital Health: Episode 7 - Australia
18 Jun 2020
Flattening the Curve with Digital Health: Episode 6 - Thailand
10 Jun 2020
Flattening the Curve with Digital Health: Episode 5 - Japan
04 Jun 2020
Flattening the Curve with Digital Health; Episode 4 - Malaysia
23 Sep 2020
Adapting to COVID 19, and driving a pivotal change in drug trials, market penetration, pricing and regulatory compliance
02 Sep 2020
Celebrating and learning from COVID 19 success stories to shape new frontiers in patient experience, healthtech and innovation.
21 May 2020
Flattening the Curve with Digial Health - Episode 2: Singapore
28 May 2020
Flattening the Curve with Digital Health: Episode 3 - South Korea
14 May 2020
Flattening the Curve with Digital Health - Episode 1 - China
14 Oct 2020
Asia's Premier Partnering Event for the Global Biotechnology Industry. This year’s exhibition will be held as originally planned at Pacifico Yokohama. BioJapan partnering is available both physically and virtually. Plus some seminars will be available online.
22 Jul 2020
Due to the COVID-19 pandemic affecting international travel, this year's event will be a unique blend of online and live gatherings — BIO Asia–Taiwan 2020 Online + Live, to be held July 22-26 in Taipei, Taiwan.
03 Nov 2020
Your go-to event to reach out to key decision makers in the pharmaceutical industry. The event will be delivered digitally from 3-5 November 2020.
09 Dec 2019
The ASEAN Emerging Researchers Conference is a flagship programme of the ASEAN Young Scientists Network; the official platform for young researchers in the region.
08 Dec 2020
Asia's pharma & biotech virtual festival - Phar-East is the premier meeting place for senior executives from Asia’s pharma and biotech industry.
26 Feb 2020
Japan's Leading Exhibition for Pharmaceutical R&D and Manufacturing Technologies!

Researchers

Duke-NUS Medical School
Dr Kwa is currently a Pharmacy Clinician Scientist and Assistant Director, Pharmacy (Research), at the Singapore General Hospital. She specializes in critical care medicine, infectious diseases and antimicrobial resistance research.
Duke-NUS Medical School
 Liu Nan
Dr Liu Nan is an Associate Professor at Centre for Quantitative Medicine and Programme in Health Services and Systems Research, Duke-NUS Medicine School. His research focuses on health services research, emergency and prehospital care, cardiology, medical informatics, and health innovation
Suraj Bhattarai is a global health specialist and tropical medicine physician with research interests in infectious disease epidemiology and surveillance, health systems, and urban health. He is a co-founder and research fellow at the Global Institute for Interdisciplinary Studies, a Kathmandu-based academic institute that promotes and conducts interdisciplinary research. He is a member of Global Young Academy and an Alumni steering committee member of IAP-Young Physician Leaders Programme. He obtained medical training in Nepal and masters in Tropical Medicine & International Health from the LSHTM, UK.
Osaka City University
Takami Tomiyama
Takami Tomiyama is currently an Associate Professor at the Graduate School of Medicine of Osaka City University.
International Islamic University Malaysia (IIUM)
Dr. Salizar Binti Mohamed Ludin is an Assoc. Prof at the Kulliyyah of Nursing of International Islamic University Malaysia.
Universiti Teknologi MARA (UiTM)
Department of Microbiology / Biomolecular Sciences Universiti Teknologi MARA Malaysia
Osaka City University
Dr. Akira Kaneko
Akira Kaneko was appointed as Professor of Parasitology of Osaka City University in 2010. Since then, he has conducted global health research with a particular focus on malaria elimination on islands in Vanuatu, Oceania and Lake Victoria, Kenya.
Daegu Gyeongbuk Institute of Science and Technology (DGIST)
Jung Ah Cho
Jung Ah Cho is a Visiting Professor at the School of Undergraduate Studies, College of Transdisciplinary Studies, DGIST.
Osaka City University
Prof. Hiromitsu Toyoda
Hiromitsu Toyoda is an associate professor at the Graduate School of Medicine of Osaka City University.
Osaka City University
Kazuhisa Asai
Kazuhisa Asai is currently an associate professor at the Graduate School of Medicine of Osaka City University.
Osaka City University
Tomoya Kawaguchi is a professor at Osaka City University. His top areas of expertise are Lung Cancer, Non-Small Cell Lung Cancer, EGFR Positive Lung Cancer, and Chronic Obstructive Pulmonary Disease.
The Education University of Hong Kong (EdUHK)
Picture of Dr. Anna Kam Chi-shan
Dr.Anna Kam's research interests include advanced technologies in aural rehabilitation, automated hearing screening, tinnitus management and auditory processing.
The Education University of Hong Kong (EdUHK)
Dr. Yuen has dual professional qualifications as an audiologist and a speech-language pathologist (or speech therapist). He is also an experienced cochlear implant clinical specialist audiologist.
Duke-NUS Medical School
Picture of Ann-Marie Chacko
Prof. Ann Marie Chacko lead the translational efforts for a portfolio of in vivo PET, SPECT, CT and optical imaging agents that span key therapeutic areas including oncology, immunology, infectious disease and neurobiology.
Duke-NUS Medical School
Prof. Patrick Tan's research focuses on developing genomic approaches to unlock the molecular and clinical diversity of gastric cancer (aka stomach cancer)- a leading cause of global cancer mortality.
Daegu Gyeongbuk Institute of Science and Technology (DGIST)
Picture of Prof.Sohee Kim
Prof.Sohee Kim's research focuses are the development of 2D and 3D flexible neural interfaces including brain interfaces, peripheral nerve interfaces, retina interfaces; polymer-based microfabrication technologies for soft bio-MEMS (micro-electro-mechanical system); and electrophysiology tools for zebrafish
Duke-NUS Medical School
Picture of Prof. David Bruce Matchar
Prof Matchar's research relates to clinical practice improvement - from the development of clinical policies to their implementation in real world clinical settings
Duke-NUS Medical School
Prof. Ooi Eng Eong
Professor Ooi Eng Eong is a clinician-scientist by training and his research on dengue is positioned at the interface between clinical epidemiology, virology and immunology. His laboratory is interested in how antibodies either protect against or enhance dengue virus infection and what viral factors influence epidemic dengue activity.
Hiroshima University
Yohei Kawano is currently and Associate Professor at the Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
Hiroshima University
Prof. Kiyomi Shitaoka's research aims to obtain effective antibody genes and T cell receptor genes by single-cell analysis of B cell and T cell receptors on lymphocytes. In addition, to apply these genes to develop new treatments for overcoming infectious diseases and cancer.
Hong Kong Baptist University (HKBU)
Picture of Dr. Ren Kangning
Dr. Ken is currently an assistant professor in the department of Chemistry at HKBU. His current research interests center on advanced analytical chemistry technologies, with particular emphasis on creating and applying novel instrumental analysis technologies based on microfluidics and materials engineering.
Hiroshima University
Prof. Tomoharu Yasuda
Prof. Tomoharu Yasuda's laboratory studies how immune system is regulated through the antigen receptor, intracellular signaling and lymphocyte programming.
Duke-NUS Medical School
Picture of Prof. Antonio Bertoletti
Prof. Antonio Bertoletti's current research focuses on the development of new immunological based therapies (TCR-redirected T cells, HLA-peptide specific antibodies) for the treatment of HBV and Hepatocellular carcinoma (HCC), and the characterization of human intra-sinusoidal hepatic immune system.
Duke-NUS Medical School
Picture of Anthony Tanoto Tan
Dr. Anthony Tan is actively involved in clinical trials in Singapore and China to test the safety and efficacy of adoptively transferring T cells engineered against HCC with HBV integration in collaboration with Lion TCR Pte Ltd.
Picture of Goh Bee Tin
Cl A/Prof Goh Bee Tin is Head and Senior Consultant in the Department of Oral and Maxillofacial Surgery (OMS), Research Director and Deputy Director (Research and Education) at the National Dental Centre of Singapore (NDCS)Education. Her research interests include bone tissue engineering and mandibular reconstruction.
Hong Kong Baptist University (HKBU)
Picture of Ken Yung Kin-Lam
Professor Ken's current research mainly focuses on the causes and treatments of neurodegenerative diseases. His lab has developed a nanomaterial-based technology for harvesting autologous neural stem cells from the brain of living subjects.
Dr. Yuichi Ohya
Dr Yuichi Ohya’s research fields are functional polymers and biomaterials, especially biodegradable polymers and drug delivery systems.
Ana Carina Manjua
Ana Carina Manjua's current PhD work is in the design and fabrication of a biological inspired artificial microfluid platform for drug screening.
Dr. Indika Neluwa-Liyanage is a lecturer in Biochemistry at the Faculty of Medical Sciences of University of Sri Jayewardenepura. His research focuses on the metabolic alterations underlying autism spectrum disorders and inherited metabolic disorders.
Dr. Mohammed N. Abdulrazaq is currently an Assoc. Prof. at Department of Engineering & Technology, Management & Science University (MSU), Malaysia.