Medicine

News

18 Jun 2021
A signalling protein thought to be able to treat liver damage in paracetamol toxicity could actually worsen it. Instead, Singapore scientists discovered, blocking its effects could be the way forward.
17 Jun 2021
Cryo-electron microscopy and computer simulations uncover how a cellular protein helps transport omega-3 fatty acids to the brain and eye, with implications for drug development.
A fluorescent micrograph of a cross-section through an epidermal blister on mice skin
14 Jun 2021
A team of scientists has shown that the healing of skin blisters is driven by hair follicle stem cells, which delay their own development in the process.
11 Jun 2021
• Glioblastoma (GBM) is a highly aggressive type of brain cancer. Even with current standard of care, 50% of patients die within 15 months of diagnosis. • This complex cancer is difficult to treat due to its location, structure, ability to spread quickly, high recurrence rate and severely limited treatment options. • GBM tumours can look identical under the microscope but respond differently to the same treatment. • With a national grant of about S$10 million, researchers in Singapore are working with overseas collaborators to address these challenges and develop new diagnostic and treatment options so patients can receive effective targeted therapy.
14 May 2021
Researchers have observed DNA spooling and unspooling in real time using CRISPR to attach fluorescent tags to very specific DNA points in living cells.
long tailed macaque
13 May 2021
A simple tool allows researchers to track how different subpopulations of the Plasmodium knowlesi parasite are changing over time.
CityU millirobots
13 May 2021
A spray-on magnetic coat turns any object into a robot controlled by a magnetic field. The biocompatible robots can walk, crawl and roll, and switch motions on demand.
UNIST UTI test
13 May 2021
A spinning toy meets hydrodynamics and sets point-of-care diagnostics in motion.
graphene battery concept
13 May 2021
The trick to extremely thin supercapacitors with improved performance is spraying graphene ink at an angle.
11 May 2021
First-of-its-kind in Singapore, the clinical trial will test a technology that enables specific cell therapy products to be manufactured for use in patients.
22 Apr 2021
A mitochondrial peptide called MOCCI has a surprising sidekick, and they work together to regulate inflammation and immunity, Singapore researchers reveal.
15 Apr 2021
A five-year study in Singapore has highlighted that chronic wounds among patients with diabetic foot ulcers and bed sores led to longer hospital stays.
07 Apr 2021
New national body established to further research insights, improve patient outcomes and create new economic opportunities for the biomedical technology industry.
One of the calves used in the clinical studies of FMR efficacy
02 Apr 2021
Scientists in Japan have developed and tested a novel probiotic formulation to control severe diarrhea in calves, ensuring their health and reducing mortality, and in turn reducing economic loss.
01 Apr 2021
A series of studies led by HKBU researchers have revealed that hyocholic acid and its derivatives (collectively known as HCAs), a component of bile acids that facilitate fat digestion, are a promising risk indicator of type 2 diabetes. The strong efficacy of HCAs in regulating blood glucose levels and protecting against diabetes has also been uncovered.
31 Mar 2021
Researchers reveal through a systematic review of 158 articles detailing quality improvements in pediatric intensive care units mainly throughout North America and the U.K. that despite having a median score of 11.0 on the Quality Improvement Minimum Quality Criteria Set, only 17% of them were considered high quality by achieving a 14-16 score, and only 5% cited Standards for QUality Improvement Reporting Excellence (SQUIRE) guidelines for reporting quality improvement works.
29 Mar 2021
Multi-country trial finds low-cost intervention to improve hypertension management in rural communities is cost-effective. Consisting of home visits by community healthcare workers, physician training and coordination with public health care infrastructure, the intervention can be scaled up in low- and middle-income countries.
26 Mar 2021
An ‘eat-me’ signal displayed on cell surfaces requires activation of a lipid-scrambling protein by a nuclear protein fragment.
25 Mar 2021
Professor David Matchar and his team from the Health Services and Systems Research (HSSR) Programme at Duke-NUS bagged two prestigious awards at the International Stroke Conference 2021, held virtually on 17-19 March, 2021.
25 Mar 2021
Through a series of experiments using nasal polyp organ culture and mouse models of restraint stress, researchers unveil relationship between presence of corticotropin-releasing stress hormone and increase in and degranulation of allergy-causing mast cells.
24 Mar 2021
Study shows that antibody longevity varies widely from 40 days to as long as several decades and not everyone who has recovered from COVID-19 is immune from reinfection. Individuals with low levels of neutralising antibodies may still be protected if they have robust T-cell immunity. Blood tests and a computer algorithm suggest annual vaccinations might be needed for some individuals to prevent future outbreaks of COVID-19.
16 Mar 2021
New research from Duke-NUS Medical School, and the Agency for Science, Technology and Research identifies chemotherapy-resistant cancers’ escape mechanism, which offers new anti-cancer treatment options.
09 Mar 2021
The world’s first international online training session utilizing advanced 3D sinus models and a telemedicine system has taken place, highlighting a new mode of medical training in Covid-19 era.
Hirofumi Sawa, MD, Ph.D.
04 Mar 2021
This article is an excerpt from the Hokkaido University research magazine “Tackling Global Issues vol.3 Fighting the menace of zoonosis" (link below).
03 Mar 2021
Osaka City University finds that the chemical sesaminol, naturally occurring in sesame seeds, protects against Parkinson’s disease by preventing neuronal damage that decreases the production of dopamine. In vitro experiments show sesaminol handle oxidative stress in cells by regulating the production of reactive oxygen species and the movement of antioxidants. In vivo experiments reveal that a diet of sesaminol increases production of dopamine and significantly improve motor functions in mice.
A research team led by Professor Gary Wong Ka-Leung (centre), Dr Lung Hong Lok (right) and Dr Law Ga-lai develop a novel dual-targeting drug for treating cancers associated with EBV.
02 Mar 2021
A Hong Kong Baptist University-led (HKBU) research team has developed a novel drug which has the potential to become a next-generation treatment for cancers associated with Epstein–Barr virus (EBV).
25 Feb 2021
Researchers from Tohoku University have developed a biobattery-powered device capable of both delivering large molecule pharmaceuticals across the skin barrier and extracting interstitial fluid for diagnostic purposes.
His-CYGB deactivates HSCs and inhibits liver fibrosis
15 Feb 2021
Osaka City University paves way for liver health by discovering the use of cytoglobin in anti-fibrotic therapy.
When quiescent neural stem cells in the fruit fly larval brain are activated, they can generate new neurons. In the image, the nucleus of quiescent neural stem cells is labelled by a marker of neural stem cells named Deadpan in magenta, and the cell outline is marked in green.
11 Feb 2021
A brain enzyme activates dormant neural stem cells, revealing how defects in its gene could lead to neurodevelopmental disorders.
08 Feb 2021
Researchers from Hong Kong Baptist University (HKBU) and the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have jointly developed the Spermine Risk Score which, coupled with the use of a urine test, provides a non-invasive and more reliable method for the diagnosis of prostate cancer. In a study conducted by the researchers, about 37% of the patients, who were ultimately found to have no prostate cancer, can avoid undergoing a prostate biopsy procedure.

Events

07 Oct 2021
The National Healthcare Group (NHG) is proud to present the 19th Edition of the Singapore Health & Biomedical Congress (SHBC).
24 Feb 2021
INTERPHEX Week Osaka is Asia's leading exhibition for pharmaceutical industry, consists of 2 exhibitions for pharmaceutical technologies - INTERPHEX OSAKA (Manufacturing & Packaging) and PharmaLab Expo OSAKA (Pharma R&D and Drug Discovery).
23 Nov 2020
Global health emergencies look set to be a part of our lives. What awaits us in 2021 and what lessons can we draw from COVID-19 coverage? How can we support newsrooms and journalists for more informed and impactful journalism about global scientific, technical and human challenges? What role does journalism play in seeking solutions for a better world that is both healthy, and sustainable?
27 Nov 2020
ACRLS 2020 aims to contribute to strengthening cooperation and relationship among members worldwide and forming a strong global network by providing various benefits to robotic clinics in rapidly growing nations throughout Asia.
25 Nov 2020
Asia's Leading Pharma & Bio Tech Show will be held as scheduled from November 25-27, 2020 at Makuhari Messe, Japan. It will be held both on-site and online.
16 Nov 2020
Optimising Clinical Trials | Commercialising Great Science | Partnering for Growth
02 Nov 2020
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
01 Oct 2020
The 6th annual RNA Biology Symposium jointly organized by the RNA Biology Centre of CSI Singapore (NUS), Skin Research Institute of Singapore (A*STAR), Duke-NUS Medical School, School of Biological Sciences (NTU) and Singapore-MIT Alliance for Research and Technology (SMART)
The Khwarizmi International Award (KIA) acknowledges the efforts made by researchers, innovators and inventors from across the globe and to appreciate their high quality research work and contributions to different fields of science and technology.
26 Jun 2020
Flattening the Curve with Digital Health: Episode 7 - Australia
18 Jun 2020
Flattening the Curve with Digital Health: Episode 6 - Thailand
10 Jun 2020
Flattening the Curve with Digital Health: Episode 5 - Japan
04 Jun 2020
Flattening the Curve with Digital Health; Episode 4 - Malaysia
23 Sep 2020
Adapting to COVID 19, and driving a pivotal change in drug trials, market penetration, pricing and regulatory compliance
02 Sep 2020
Celebrating and learning from COVID 19 success stories to shape new frontiers in patient experience, healthtech and innovation.
21 May 2020
Flattening the Curve with Digial Health - Episode 2: Singapore
28 May 2020
Flattening the Curve with Digital Health: Episode 3 - South Korea
14 May 2020
Flattening the Curve with Digital Health - Episode 1 - China
14 Oct 2020
Asia's Premier Partnering Event for the Global Biotechnology Industry. This year’s exhibition will be held as originally planned at Pacifico Yokohama. BioJapan partnering is available both physically and virtually. Plus some seminars will be available online.
22 Jul 2020
Due to the COVID-19 pandemic affecting international travel, this year's event will be a unique blend of online and live gatherings — BIO Asia–Taiwan 2020 Online + Live, to be held July 22-26 in Taipei, Taiwan.
03 Nov 2020
Your go-to event to reach out to key decision makers in the pharmaceutical industry. The event will be delivered digitally from 3-5 November 2020.
09 Dec 2019
The ASEAN Emerging Researchers Conference is a flagship programme of the ASEAN Young Scientists Network; the official platform for young researchers in the region.
08 Dec 2020
Asia's pharma & biotech virtual festival - Phar-East is the premier meeting place for senior executives from Asia’s pharma and biotech industry.
26 Feb 2020
Japan's Leading Exhibition for Pharmaceutical R&D and Manufacturing Technologies!
26 Nov 2019
Vaccine World Asia 2019 will bring together leading experts to discuss the latest technological advancements and spearhead scientific innovation in the development and manufacture of vaccines for key diseases such as Dengue, Chikungunya, Malaria, Tuberculosis etc.
07 Nov 2019
Fostering Young Intellectuals for a Better Future
03 Oct 2019
Deadline for online registration 20 September 2019! We are excited to host our 5th annual RNA Biology Symposium by the RNA Biology Centre of CSI Singapore, NUS. It will be held at the Clinical Research Centre (MD11) Auditorium, 10 Medical Drive, Singapore 117597.
20 Nov 2019
Organising partner - the Australian Digital Health Agency
07 Oct 2019
Tracks include: Sustainability & Growth; Patient Experience; Unlocking the Value of AI; Value-based Care.

Researchers

University of Malaya
Assoc Prof Dr Loh Siew Yim is a senior lecturer at the faculty of Medicine in University of Malaya, Malaysia Her research interest is cancer survivorship, and behavioural medicine .
Currently a research assistant in the laboratory of green energy in Zhejiang University of Technology.
Earth-Life Science Institute (ELSI), Tokyo Institute of Technology
Tony Z. Jia is a researcher at Japan’s Earth-Life Science Institute (ELSI), based at the Tokyo Institute of Technology. His research focuses on astrobiology, prebiotic chemistry, and origins of life.
Ulsan National Institute of Science and Technology (UNIST)
Associate Professor Hajin Kim is a biomedical engineer at the Single Molecule Biophysics Laboratory, Ulsan National Institute of Science and Technology, South Korea.
Universiti Malaysia Sarawak
Dr Paul Cliff Simon Divis is the director of Malaria Research Centre at Universiti Malaysia Sarawak (UNIMAS).
University of Malaya
Picture of Durriyyah Sharifah Hasan Adli
The Neuroscience Research Group is a multi-disciplinary team investigating the nervous system. They are focusing on animal behavioral models for memory in the laboratory. They are studying the effects of food, such as Habbatus Sauda/Black cumin (Nigella sativa) and honey, on brain microstructures and memory. They also compare Islamic and neuroscience perspectives on issues like learning and sleep for children with and without autism spectrum disorders.
Duke-NUS Medical School
Babita Madan is an assistant professor at the Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore.
Duke-NUS Medical School
David Virshup, M.D., is Director of the Programme in Cancer and Stem Cell Biology (CSCB) and Professor at Duke-NUS Medical School and is jointly appointed as Professor of Pediatrics at Duke University in North Carolina.
I do research on dysmennorrhoea and gender-based violence. I am a pioneer in registered clinical trials on indigenous and Ayurveda medicines in Sri Lanka. I have approval for a herbal preparation, for COVID patients.
My PhD research entitled "No harm done? The experiences of women who inject drugs accessing harm reduction in Indonesia" examines the role of social, political and economic impacts on women who use/inject drugs and the correlation with increase rates of HIV/HCV and incarceration.
National University of Singapore
Picture of Audrey Chia
I work at the intersection of Business, Medicine and Environment. Many of the world’s current problems are best addressed from multiple perspectives. I examine issues ranging from sustainable development, pandemics, diversity, environment, social innovation and philanthropy, and suggest how we can do better.
Nanyang Technological University
Picture of Sravya Tekumalla
Dr. Sravya Tekumalla is currently a Principal Investigator in Nanyang Technological University, Singapore, where she works as a Presidential Postdoctoral Fellow. In addition, she also leads a small team of staff and students working in the domain of metal additive manufacturing (commonly known as 3D printing). Her current research interests include engineering microstructures via alloy design and process control to develop next-generation metallic materials with tailored property profiles. One such application of her current work is in the design and development of novel, low modulus-high strength-durable titanium alloys intended for biomedical applications (in components such as implants) that have the potential to transform the landscape of the biomedical industry.
Tohoku University
I am engaged in the development of a new device for embryo evaluation which measures embryo oxygen consumption and a new medication for infertility. Recently, I focused on causative genes of disorders of sex development and searched pathogenic variants using a whole-genome reference panel constructed by Tohoku Medical Megabank Organization.
Duke-NUS Medical School
Professor Linfa Wang is a Professor with the Emerging Infectious Diseases Programme at Duke-NUS Medical School, Singapore.
Associate Professor Sophia Archuleta is the Head and Senior Consultant of the Division of Infectious Diseases at the National University Hospital, Singapore.
Nimanthi Jayathilaka is a professor at the Department of Chemistry, University of Kelaniya, Sri Lanka.
Hira Khalid is an associate professor at the Department of Chemistry of Forman Christian College University, Lahore, Pakistan.
Universiti Teknologi MARA (UiTM)
Dr Heo is currently a senior lecturer at the Department of Microbiology and Parasitology, Faculty of Medicine, Universiti Teknologi MARA, Malaysia.
Duke-NUS Medical School
Dr. Tazeen Jafar is a global health leader and expert with a focus on implementation research in hypertension, cardiovascular disease, and chronic kidney disease.
Duke-NUS Medical School
Prof. Wang Hongyan is the deputy programme director and principal investigator of the laboratory of Neural Stem Cell at Duke-NUS Medical School, Singapore.
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
Yuichi Taniguchi is a professor at the Institute for Integrated Cell-Material Sciences (iCeMS)/Graduate School of Biostudies, Kyoto University, a team leader at RIKEN Center for Biosystems Dynamics Research and an adjunct professor at Graduate School of Frontier Biosciences, Osaka University.
International Islamic University Malaysia (IIUM)
Dr Ramli is a Professor at Department of Psychiatry, Kulliyyah of Medicine at the International Islamic University Malaysia (IIUM).
Hokkaido University
Ji-Won Lee is an assistant professor at the Faculty of Dental Medicine at Hokkaido University, Japan,
Hokkaido University
Tadahiro Iimura is a professor in the Faculty of Dental Medicine, the Division of Dental Medicine, the Department of Pathobiological Science, Hokkaido University, Japan
Hokkaido University
Tsuyoshi Mita is a specially appointed associate professor at the Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, Japan.
Hokkaido University
Manabu Tokeshi is a Professor at the Division of Applied Chemistry at Hokkaido University.
Tohoku University
A professor at the Bone Regenerative Engineering Laboratory, Regenerative and Biomedical Engineering Division, Graduate School of Biomedical Engineering, Tohoku University, Japan
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
My research background covers multidisciplinary fields such as Pharmaceutics, Cancer Nanomedicine, Bioengineering and Organ-on-a-chip platforms. My current research focuses on the development of dynamic biological barriers on a chip such as blinking human cornea on a chip.
Hokkaido University
Hidemitsu Kitamura is an associate professor at the Section of Disease Control, the Institute for Genetic Medicine, Hokkaido University, Japan.
The Chinese University of Hong Kong (CUHK)
Li Zhang is an Associate Professor in the Department of Mechanical and Automation Engineering (MAE) and an associate faculty member in Chow Yuk Ho Technology Centre for Innovative Medicine (TIM) and T Stone Robotics Institute (CURI) at The Chinese University of Hong Kong (CUHK). He is also the co-director of CAS SIAT-CUHK Joint Laboratory of Robotics and Intelligent Systems.