Medicine
News
08 Feb 2023
Hokkaido University researchers have developed a novel method to design and develop peptide antibiotics in large numbers, which will prove critical to controlling antibiotic resistance.
02 Feb 2023
Blocking an immune-regulating protein reverses the damage caused by acute and chronic kidney disease, a preclinical study suggests.
02 Feb 2023
A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.
30 Jan 2023
Researchers from Osaka University compared the sensitivity of rapid antigen tests (RATs) and polymerase chain reaction (PCR) tests for the Omicron variant of COVID-19 using data produced by the Japan Professional Football League. They found the comparative sensitivity of RATs for Omicron was not affected by the duration from the onset of symptoms to testing.
27 Jan 2023
New research found that periodontitis, a common gum infection known to worsen other systemic diseases, could also be linked to atrial fibrosis — potentially clarifying its previously unknown connection with atrial fibrillation.
25 Jan 2023
Researchers from Osaka University have identified a protein, FER1L5, that is essential for sperm to acquire fertilizing ability. Sperm from mice lacking this protein were unable to undergo the “acrosome reaction”, which releases molecules that facilitate fertilization, resulting in impaired male fertility. As FER1L5 is also present in human sperm, this work may lead to new diagnostic methods and treatments for male infertility in humans.
20 Jan 2023
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a stem-cell based therapy for pets with cancer, how meditation could affect our gut microbiome, and an edible mushroom that contains a deadly nerve gas.
19 Jan 2023
Researchers at Kanazawa University report in Nano Letters how high-speed atomic force microscopy can be used to assess the effectivity of spike-neutralizing antibodies for preventing COVID-19. The use of such antibodies offers a promising alternative to vaccines.
19 Jan 2023
Imagine if your t-shirt could take your sweat and analyze it for health abnormalities. Well, this is much closer to reality after a recent breakthrough by a research group led by a Tohoku University assistant professor. The group created the first microelectronic fiber with microscopic parameters that is capable of analyzing electrolytes and metabolites in sweat.
13 Jan 2023
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the growing trend of unique name pronunciations in Japan, an aquarium that can tell you about which fish you are looking at, and which professional baseballs are slipperiest.
13 Jan 2023
Researchers led by Osaka University demonstrated the role of endothelial cell-specific protein Roundabout4 (Robo4) in the reduction of vascular permeability and mortality in mouse models of severe infection. The research team identified a drug inhibitor that increased Robo4 expression and reduced mortality in sepsis and SARS-CoV-2 mouse models of infection. These findings may aid in the development of drugs to reduce the mortality rate of severe infectious diseases.
04 Jan 2023
Researchers from Osaka University found that dietary supplementation with tricaprin results in coronary artery plaque regression and resolution of symptoms in patients with triglyceride deposit cardiomyovasculopathy, a treatment-resistant form of coronary artery disease. These findings represent a conceptually novel treatment for coronary atherosclerosis that paves the way toward establishing a multi-faceted approach to caring for patients with this condition.
23 Dec 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are how a wasp uses its genitals to defend itself, a compound commonly found in mushrooms that could delay cognitive decline, and sunshine as a cure for myopia.
23 Dec 2022
The ability to see what’s happening inside the body in real-time and at a high resolution is a capability that ultrasound grants orthopedists at a low cost to patients. Ultrasound-guided diagnosis, however, remains relatively new in the field. Dr. Yuko Nakashima is here to change that for Japan with the help of her fellow “e-girls.”
22 Dec 2022
A research team led by Osaka Metropolitan University has revealed a difference in neural activity in response to visual food stimuli, depending on whether those stimuli are presented consciously or unconsciously. Using a questionnaire to assess the study participants, the team found that this difference was associated with their scores on eating behaviors, including emotional eating and cognitive restraint of food intake. These results indicate that eating behavior cannot be understood without taking into account both unconscious and conscious neural processes.
20 Dec 2022
Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.
19 Dec 2022
Researchers from Osaka University found that the “belief in just deserts”, which is the idea that infected individual deserves to be infected, was associated with attitudes about government restrictions during public health emergencies in the context of the COVID-19 global pandemic. This information could lead to new strategies for combating discrimination, prejudice, and stigma against COVID-19 patients.
19 Dec 2022
A research team led by Hong Kong Baptist University (HKBU) has identified a molecular target for bone anabolic therapies using a selected aptamer that serves as an inhibitor of sclerostin, a protein that prevents bone growth. The discovery offers hope for the development of an effective next-generation treatment for osteoporosis and osteogenesis imperfecta that is free of cardiovascular risk compared to the marketed antibody drug.
19 Dec 2022
Researchers from Osaka University have developed a culture system using pluripotent cells from southern and northern white rhinos, which was refined to produce primordial germ cell-like cells (PGCLCs). These cells are the equivalent of primordial germ cells, the origin of eggs and sperm. The study marks an important first step in the potential production of northern white rhino gametes, which could be used in breeding programs, and is the first to induce PGCLCs in a wild animal.
16 Dec 2022
Scientists developed a novel device that predicts whether an ICU patient taken off mechanical ventilation is likely to suffer from respiratory emergencies, helping critical care teams to provide immediate life-saving interventions.
15 Dec 2022
Researchers led by Osaka University report the development of INCIDER, a fluorescent sensor system that enables high-contrast microscopic imaging of temporal changes in cellular interactions mediated by the N-cadherin molecule. This sensor system, which emits much brighter fluorescence than the currently used system while detecting these interactions, is expected to have a wide range of applications in developmental biology, neuroscience, and other fields.
14 Dec 2022
Researchers led by Osaka University generated a time-stamping method to trace the development and survival of plasma cells in the bone marrow and spleen. Using a mouse model in which plasma cells were fluorescently labeled in an inducible manner, they found that plasma cells were continuously replenished by new cells, a small portion of which differentiated into long-lived plasma cells (LLPCs). These findings may aid in the development of new vaccines that efficiently induce LLPCs.
13 Dec 2022
A study by Osaka University has shown that the prevalence of non-communicable diseases, which included hypertension, hyperlipidemia, diabetes, and mental disorders, increased after the Fukushima disaster and the COVID-19 outbreak. These findings emphasize the importance of improving post-disaster health promotion strategies and recommendations.
09 Dec 2022
A new coating for tiny packages called liposomes could allow them to carry vaccines and drugs into and around the body more safely.
09 Dec 2022
Silencing the gene, called WWP2, in patients in the early stages of cardiomyopathy could delay progression to heart failure by controlling immune cell infiltration and activation, and halting the formation of excessive scar tissue, preclinical data suggest.
09 Dec 2022
− The European Commission Approved QDENGA (TAK-003) for Use in Individuals Four Years of Age and Older [i]
− QDENGA Becomes the Only Dengue Vaccine Approved in the EU for Use in Individuals Regardless of Previous Dengue Exposure [i]
08 Dec 2022
Quinine and various drugs based on its chemical structure have been used to treat malaria for centuries. But parasites resistant to antimalarial drugs are becoming apparent. To pave the way for future medicine development, an efficient way to synthesize quinine was needed. And now a research team from Tohoku University has achieved just that.
08 Dec 2022
Giants in History: Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Events
12 Feb 2007
The workshop will bring together leading investigators from industry, universities, as well as research institutes in Southeast Asia to present and discuss the use of various animal models including Drosophila, zebrafish, chick and mouse in their research.
15 Oct 2006
Training in good counseling skills is a priority to enable the infected learn how to live positively. Counseling is best done by those already infected. They have the experience of living with the virus themselves. What they need next are communication and counseling skills so as to reach those newly infected and affected.
24 Oct 2006
The objective is for the protein researchers to keep abreast with this rapidly growing area, and to promote exchange of knowledge and expertise among the protein researchers in Thailand.
02 Oct 2006
The field of bioinformatics has been a major part of drug discovery, with a key role in validating drug targets. This objective of this course is to introduce the participants to the current genomic information of insect vectors and to promote applications of bioinformatics and post-genomic tools in molecular entomology research.
18 Sep 2006
The aims of the initiative are to strengthen research capability of scientists in endemic countries and to promote application of bioinformatics in tropical diseases research.
12 Nov 2006
Theme: Development and modern scientific technology of traditional medicine and natural health products.
29 Jul 2006
We believe the key to stay competitive is Intelligence. What kind of intelligence is the right kind for the new competitions? How would Intelligence help us feel and be empowered, and empower our machines to be more efficient and helpful?
01 Jul 2006
The seminar aims at highlighting the strategic initiatives taken by IndianJournals.com in the field of e-publishing & promotion of Indian Publications
24 Apr 2006
Meeting of Pandemic experts, scientists and Asian national granting councils in Beijing, April 24-26, at the Beijing Friendship Hotel, Bai Shi Qiao Road, Haidian District, Beijing, China. Media briefing
24 May 2006
The inaugural Penang International Postgraduate Convention will take place with the following conferences: 1st Health and Medical Science Conference; 3rd Life Sciences Postgraduate Conference; 1st Penang International Conference for Young Chemists
10 Mar 2006
Many insights will be gained by discovering more about the mechanisms of normal brain development, since abnormal development can lead to a range of cognitive disorders from mental retardation and learning disabilities to schizophrenia.
08 Mar 2006
The Asian Conference on Diarrhoeal Diseases and Nutrition (ASCODD) is held regularly every two years in different locations throughout Asia. The next event is the 11th ASCODD, to be held in Bangkok, Thailand, 8-10 March 2006.
23 Jan 2006
"Emergencies and Disasters: Pearls for the 21st Century Primary Health Care Provider" is especially significant in this day of major calamities and disasters which unexpectedly come at any time and any place. Readiness to meet the challenges that such emergencies bring may be the deciding factor that will determine the possible outcome.
05 Jun 2006
Sample of abstract:“Healers use a variety of material medica including plants, animals and minerals. There were 363 species/types recorded for treating 91 health conditions.” The annual meeting of the Society of Economic Botanists will bring together the current research in this important and interesting field
06 Aug 2006
By 2006 the tangible impact on human health of the Human Genome Project and advances in genomic science and biotechnology will make attendance at the 11th Congress essential for health professionals and genetic scientists alike.
19 Jun 2006
bioLOGIC Europe is firmly established as Europe’s most prestigious series of strategic biomanufacturing conferences
05 Jun 2006
This conference is where the ideas, intelligence and relationships develop the business models of the future
20 Mar 2006
It is a knowledge experience, business meeting and marketplace from all parts of the world. A unique chance to meet, learn from and network with the Directors of the entire global industry in one place.
14 Jan 2006
This event is Free of charge and will be conducted in English
29 Nov 2005
A host of dignitaries, including the Prime Minister of Jordan, will join TWAS members to discuss the state of science in the developing world.
26 Aug 2006
Honey is popular as a folk medicine. In recent years, honey has been investigated for use in scientific medicine including control of wound infection, prevention of post surgical wound infections, treatment of burns and diabetic foot, to name a few.
15 Dec 2005
The 3rd International Symposium on Biotechnology will create and disseminate the fast growing knowledge for better learning in Enzyme technology, Biochemical Engineering, Fermentation technology, Tissue Culture, Genetics and Bioinformatics.
01 Dec 2005
XXV Annual Convention of National Neonatology Forum
17 Nov 2005
The 3rd Asia Pacific Conference on Reproductive and Sexual Health (3rd APCRSH) will be held in Kuala Lumpur from 17 to 21 November 2005.
19 Sep 2005
Training course on "Bioinformatics and Functional Genomics of Insect Vectors of Human Diseases"
28 Nov 2005
Hosted by The National Poison Center in Malaysia
06 Feb 2006
The 2006 Commonwealth Congress on Diarrhoea and Malnutrition will be held at ICDDR,B: Centre for Health and Population Research, Dhaka, Bangladesh, 6-8 February 2006.
11 Nov 2005
"Cancer: Are we winning the battle?" is the theme of this annual Asia Pacific congress is dedicated to presenting objective, up-to-date information on health and research in medicine today.
Researchers
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Giants in history
Henriette Bui Quang Chieu (1906 – 2012) was inspired to follow in her brother’s footsteps and become a doctor after losing her mother to tuberculosis. She studied in France and became the first Vietnamese woman to receive a medical degree. Upon her return to Vietnam, Bui was appointed head of the Department of Midwifery at Cho Lon Hospital in Ho Chi Minh City. A pioneer in gynaecology, she applied acupuncture techniques that she had learned in Japan to obstetrics. As Vietnam was still a French colony, Bui also lobbied for the rights of Vietnamese doctors, nurses, and patients.
Japanese biochemist Akira Endo (1933 – 2024) discovered the first statin, called mevastatin, which lowered cholesterol levels in the blood by inhibiting a key enzyme in the cholesterol biosynthesis pathway. His work laid the foundation for the development of statins to help patients lower their blood cholesterol levels and reduce their risk of heart disease or stroke.
Filipina paediatrician and scientist Perla Santos-Ocampo (25 July 1931 – 29 June 2012) made important contributions to treatments and policies that curbed debilitating and sometimes deadly diarrhoea-related diseases and malnutrition in children.
Singaporean physician Oon Chiew Seng (1916 – 31 March 2022) advanced dementia care and research in Singapore, and co-founded the Apex Harmony Lodge, the nation’s first nursing home for residents with dementia.
Vietnamese surgeon Tôn Thất Tùng (10 May 1912 – 7 May 1982) developed a pioneering technique that reduced the risks and mortality rate of liver operations.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
Maggie Lim (5 January 1913 – November 1995) was a Singaporean physician who promoted family planning and expanded the access to clinics to improve the quality of life for mothers and children in Singapore’s early days.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
The founder of the Adyar Cancer Institute in India, Muthulakshmi Reddy (30 July 1886 – 22 July 1968), fought to uplift women and girls from impoverished situations.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health. In relation to botany, she uncovered the means by which asexually-reproducing plants evolve into new species.
The first Thai woman to receive a degree in medicine, Margaret Lin Xavier (29 May 1898 – 6 December 1932), is best remembered for her compassion towards her less privileged patients.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
In 1915, Koichi Ichikawa along with pathologist Katsusaburo Yamagiwa became the first to prove that chronic exposure to chemicals can cause cancer.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Ground-breaking cancer researcher Kamal Jayasing Ranadive (8 November 1917 – 11 April 2001) advanced the understanding of the causes of leukaemia, breast cancer and oesophageal cancer through the use of animal models. She was also among the first to recognise how susceptibility to cancer is linked to tumour-causing interactions between hormones and viruses.
The research of Filipino pharmaceutical chemist Luz Oliveros-Belardo (3 November 1906 – 12 December 1999) focussed on essential oils and other chemicals derived from native Philippine plants.
Thai physician and conservationist Boonsong Lekagul (1907 – 1992) made major contributions to the preservation of his country’s wildlife.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Korean parasitologist Seung-Yull Cho (16 November 1943 – 27 January 2019) is remembered largely for his pioneering works to control infections caused by helminthic parasites and his contribution to journal publishing.
Fe Villanueva del Mundo (27 November 1911 – 6 August 2011) was a Filipina paediatrician who founded the Philippines’ first paediatric hospital.
After witnessing death and suffering as a youth in his home village during World War II, Nguyễn Tài Thu (6 April 1931 – 14 February 2021) set his sights on alleviating pain by becoming a doctor. After studying Traditional Chinese Medicine in China in the 1950s, Thu returned to Vietnam to serve in military hospitals. Eventually, he became the country’s foremost practitioner of acupuncture, a technique he first learned by inserting needles into himself.
Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
Wu Lien-teh (10 March 1879 – 21 January 1960) was a Malaysian-born doctor who invented a mask that effectively suppressed disease transmission. Winning the prestigious Queen’s Scholarship enabled Wu to become the first Chinese student to study medicine at the University of Cambridge.
David T. Wong (born 1936) is a Hong Kong-born American neuroscientist who is best known for discovering the antidepressant drug fluoxetine, better known as Prozac.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Tu Youyou (born 30 December 1930) is a Chinese pharmaceutical scientist who was awarded the 2015 Nobel Prize in Physiology or Medicine for her work on extracting artemisin from sweet wormwood to treat malaria.
Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.
Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine. She discovered that gout, a condition characterized by the painful inflammation of joints, was caused by elevated levels of uric acid in the bloodstream.
Min Chueh Chang (10 October 1908 – 5 June 1991) was a Chinese-American biologist who studied fertilization in mammalian reproduction.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan.
Esther Park (1877-1910), born Kim Jeom-dong, was the first female Korean physician to practise modern medicine in Korea and trained the first generation of Korean female doctors.