Medicine

News

11 Aug 2023
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are particle pollution linked to antibiotic resistance and microplastics being found in the body, fossils that show a marine reptile that used filter feeding, and how a connection in our brains compares our rewards to ones that others received.
09 Aug 2023
Researchers from Osaka University clarified the interactions of the proteins Tejas (Tej), Vasa (Vas), and Spindle-E (Spn-E) in the formation of cellular compartments known as nuage and the processing of PIWI-interacting RNA (piRNA) precursors in Drosophila melanogaster ovaries. piRNAs help prevent the transmission of genetic mutations through reproductive cells, and insight into the dynamics of piRNA formation and processing may contribute to our understanding of the mechanisms underlying reproductive disorders, including infertility.
07 Aug 2023
A research led by scientists of Hong Kong Baptist University (HKBU) found that isoliquiritigenin (ISL), a flavonoid isolated from the Chinese herbal medicine licorice, can inhibit pancreatic cancer progression. It may also enhance the efficacy of conventional chemotherapeutic drugs in treating pancreatic cancer. It is the first time that a research group reported the anticancer potential of ISL in treating pancreatic cancer.
04 Aug 2023
Osaka Metropolitan University scientists tested the antiobesity effects of Mallotus furetianus extract native to Hainan Island, China, using obesity model mice. As a result, body weight and adipose tissue weight of obesity model mice were significantly reduced by the intake of Mallotus furetianus extract. Fatty liver was suppressed and adipocyte size reduction in adipose tissue was observed. Further investigation into the mechanism revealed that fat synthesis is inhibited by suppressing the expression of several transcription factors involved in differentiation into adipocytes.
03 Aug 2023
The researchers from Osaka University showed how bone erosion caused by cholesteatoma occurs. This study showed that a subset of cells called osteoclastogenic fibroblasts expresses a protein, activin A, which causes the breakdown of the bones. Because of this discovery, novel medical treatments can be developed as first-line management for cholesteatomas.
01 Aug 2023
Researchers from Osaka University found that patients with persistently high levels of urinary albumin excretion in the long term are at high risk of new-onset heart failure. Preventive treatment associated with the lowering of urinary albumin excretion levels in these patients could reduce the risk of later heart failure or mortality.
31 Jul 2023
Researchers from Osaka University have demonstrated a proof-of-concept for identifying single nucleotides by using quantum computing. Molecular rotation patterns—and the corresponding variations in conductance—within the nanoscale gap between two electrodes enabled the development of a quantum gate for the nucleotide adenosine monophosphate. Developing quantum gates for the other three nucleotides, and incorporating this technology into DNA sequencing workflows, could revolutionize genome analysis.
28 Jul 2023
Scientists have isolated potent neutralising antibodies from a COVID-19 vaccinated SARS survivor that exhibited remarkable breadth against known sarbecoviruses. The antibodies targeted a conserved region of the spike protein and blocked receptor binding and viral fusion. These findings could guide the development of broadly active therapeutics against current and future coronaviruses.
26 Jul 2023
The consortium’s multidisciplinary executive committee comprises of both local and international oral health researchers.
25 Jul 2023
The Centre for Chinese Herbal Medicine Drug Development (CDD) of Hong Kong Baptist University (HKBU) has made significant progress in developing novel Chinese medicine for treating chronic constipation. With its success in the Investigational New Drug Application to the U.S. Food and Drug Administration (FDA), CDD has been authorised to conduct a phase I clinical trial of the new drug. This is the first time that a new botanical drug developed in Hong Kong was authorised to conduct a clinical trial in the US.
24 Jul 2023
Lactate is a byproduct of exercise and metabolism, fueling our brain when oxygen is limited. More recently, scientists have become aware of the many roles it plays in developing our nervous system. Now, researchers from Tohoku University have unearthed the cellular mechanisms by which lactate helps our brains develop.
19 Jul 2023
Scientists have combined two light wavelengths to deactivate a bacterium that is invulnerable to some of the world’s most widely used antibiotics, giving hope that the regime could be adapted as a potential disinfectant treatment.
18 Jul 2023
RNases have been proposed as a treatment against systemic autoimmune diseases. Researchers from Osaka University showed that RNases have a dual action. In some cases, RNases are detrimental and stimulate the immune response by promoting the binding of antibodies to their targets. These findings will improve the understanding and treatment of systemic autoimmune disorders.
14 Jul 2023
Researchers from Osaka University have developed a fluorescent sensor that may be useful for understanding how cells recognize themselves versus other cells when making connections in the brain. Specifically, their sensor can be used to visualize not only connections between cells, but also the disassociation of these interactions. Because neuronal self-connectivity has been implicated in brain disorders like epilepsy and autism, a better understanding of this process may result in improved therapies.
11 Jul 2023
A research team has discovered an astounding array of unexplored protein folds. This research will expand our understanding of the depth of the protein universe and the possibilities for de novo design of functional proteins.
11 Jul 2023
The physiological mechanisms underlying severe burns are not well understood. Researchers at Osaka University used mass spectrometry to identify key blood proteins associated with burn mortality. Ultimately, three proteins (HBA1, TTR, SERPINF2) were very highly correlated with morality rates. Further research into these proteins and their pathways may lead to better drugs to treat people with life-threatening burns.
Microbial cultures used in the study to investigate the biosynthesis of actinopyradizone (Photo: Kenichi Matsuda).
11 Jul 2023
The entire biosynthetic pathway of actinopyridazone has been unveiled, revealing that an unprecedented carrier protein-mediated ring-forming step is key to its synthesis.
07 Jul 2023
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a way to avoid biopsies by catching free-floating DNA, a large dip in the Earth’s surface under the Indian Ocean, and how people who brush their teeth before bed seem to have healthier hearts.
06 Jul 2023
Osaka Metropolitan University scientists have successfully developed a model that utilizes AI to accurately classify cardiac functions and valvular heart diseases from chest radiographs. The Area Under the Curve, or AUC, of the AI classification showed a high level of accuracy, exceeding 0.85 for almost all indicators and reaching 0.92 for detecting left ventricular ejection fraction—an important measure for monitoring cardiac function.
03 Jul 2023
A group of researchers at Osaka University used a noninvasive method to evaluate Cerebrovascular Autoregulation (CVAR) in patients after out-of-hospital cardiac arrest. The mortality rate increased significantly with the duration of time that CVAR was undetectable. It has been suggested that CVAR, a function that is normally present in the normal state, may be impaired after cardiac resuscitation. However, the relationship between CVAR function and patient prognosis has been unclear. The research examined CVAR over time, using the moving Pearson correlation coefficient calculated from regional cerebral oxygen saturation and mean blood pressure data, and performed a survival analysis using the presence or absence of CVAR as a time-dependent covariate. The findings of this study may first be useful in predicting neuroprognosis after cardiac resumption and may help avoid early withdrawal of treatment in those who may recover. In addition, they suggest that treatment and management that maintains proper CVAR after cardiac resumption may improve patient prognosis, which may be applied to the management of post-cardiac arrest resuscitation based on cerebral circulation to optimize treatment for each individual patient.
28 Jun 2023
Researchers from Osaka University have revealed the mechanism by which increased signaling through a pathway associated with a molecule called Wnt leads to the development of liver cancer. They identified a gene called GREB1 as a target of Wnt specifically in liver cancer. This gene alters the function of a protein called HNF4α, leading to the development of cancer. They also showed that treatment of mice with antisense oligonucleotides against GREB1 had significant anti-cancer effects.
26 Jun 2023
What scientists learned about the rare antibodies targeting SARS-CoV-2’s Achilles’ heel could help fine-tune our COVID-19 vaccine strategy for longer-lasting immunity.
Principle of Nanofluidic Aptamer Nanoarray (NANa)
23 Jun 2023
An international team led by Professor Yan Xu from Osaka Metropolitan University has developed a groundbreaking nanofluidic device, named NANa, capable of stochastically capturing and digitally detecting individual proteins at cellular concentrations. This tool, vital for precision medicine, is designed to handle tiny volumes equivalent to a single cell's contents and can identify single biomolecules even in high-concentration environments. The team plans to conduct further demonstrations using actual cell samples and explore the integration of this tool with AI and biological big data. This research could potentially revolutionize personalized disease prevention and treatment.
The 39 dogs in the study were divided into three groups based on treatment strategies (Tatsuya Deguchi, Naoya Maekawa, et al. Cancers. June 1, 2023).
23 Jun 2023
A combination of radiotherapy followed by immunotherapy is a promising strategy for the treatment of oral malignant melanomas in dogs.
Asia Research News Editor's Choice header
19 Jun 2023
A key protein for sperm maturation identified, Understanding gel formation, Urine test predicts organ diseases, A laser drills holes in a graphene film. Plus in our blog - The frogs of Borneo: more than just a race. Read all in the latest Editor's Choice.
19 Jun 2023
Researchers from Osaka University found that the binding of two proteins—Polydom and Tie1—is essential for lymphatic cell migration in the remodeling of lymphatic vessels, which transport molecules around the body. A better understanding of the development and remodeling of the lymphatic system will lead to better therapeutic options for diseases such as lymphedema, which is common in cancer patients and currently has no cure.
The transfer of pathogenic genes between not only same bacterial species but also different species
15 Jun 2023
A joint research group led by Osaka Metropolitan University has clarified how pathogenic genes in some Providencia spp., which have gained attention as causative agents of food poisoning as well as enterohemorrhagic Escherichia coli. O157 and Salmonella, are transferred within bacterial cells. Their findings are expected to provide new insights into the identification of infection routes of Providencia spp. and the establishment of preventive methods for food poisoning.
08 Jun 2023
A stem cell therapy treatment developed by Duke-NUS Medical School researchers for heart failure has shown promising results in preclinical trials. These cells, when transplanted into an injured heart, are able to repair damaged tissue and improve heart function.
05 Jun 2023
Researchers from Osaka University developed an in vivo CRISPR screen to analyze factors affecting Toxoplasma gondii fitness in healthy and immunodeficient mice. Mice were infected with Toxoplasma containing CRISPR libraries that targeted specific genes; genetic sequencing was then performed to identify which genes are important to fitness. The genetic screen clarified the contributions of host genetics and parasite genetics and can contribute to the development of strategies for toxoplasmosis treatment and prevention.
Mothers and babies in Tanzania
05 Jun 2023
App leads to better birth preparation for pregnant women

Events

13 Aug 2007
To facilitate the development of a science-based regulatory framework that would promote research, development, commercialisation as well as the growth of both local and foreign biotechnology industries in Malaysia
17 Aug 2007
For many children, learning to read seems effortless and is a normal developmental milestone. However, for some children, they have to struggle with what appears to come naturally to others and without proper support, are unable to make sense of the printed word. These children are dyslexic and suffer from dyslexia, a reading disorder.
27 Jul 2007
Chicago, USA - Chinese Health Food and its associated concepts and technologies. It will be an excellent opportunity for the international community to exchange ideas and develop a common vision for the future of Chinese health food.
21 Jul 2007
India - The growth in healthcare is creating new challenges in the adoption of healthcare standards in the emerging healthcare hubs. Four events in different cities aim to bring together all the key healthcare stakeholders.
22 Jul 2007
Sydney, Australia - As the fourth conference in the HIV Pathogenesis, Treatment and Prevention series, IAS 2007 will feature reports on the latest developments in the areas of basic, clinical and prevention science.
20 Sep 2007
Hanoi, Vietnam - Experts and scientists interested in participating in the Workshop are required to submit their nomination form by 14th August 2007. The selection of the participants will be strictly based on merit and quality of the extended abstracts of the presentation material to be submitted along with the completed Nomination Form.
28 Aug 2007
Kelantan, Malaysia - The Third National Workshop on Scientific Writing is purposely constructed to guide participants to be active and skillful in writing scientific manuscript.
12 Jun 2007
Kuala Lumpur, Malaysia - Besides the participation of the OIC affiliated institutions such as the Islamic Development Bank, ISESCO, COMSTECH, various esteemed health-related international authorities and entities, namely the World Health Organization, UNICEF, CDC-US will also participate in this exclusive event.
09 Jun 2007
Bangkok, Thailand - Avian influenza and other emerging infectious diseases are of global public health concerns. This workshop will provide a platform for scientists in Thailand and the UK to discuss current issues and establish future research collaborations.
21 Jun 2007
Atlanta : This session will share the experience on possible resolution on the quality control, the interaction of botanical drugs with western medicine and the R&D strategy and the approval of the first NDA on botanical drugs in Taiwan.
02 Jun 2007
Shanghai, China - This symposium has as objective to provide participants with an insight into updated infertility management and a glimpse into the future. Participants will be provided with information on epidemiology of infertility in Asia and its impact on society and infertility service provided.
24 Jun 2007
Victoria, Australia : The themes are as broad or as narrow as you would like them to be: a tool to think about health, wellbeing, mobility in Asia and the Pacific.
27 Apr 2007
London - World renowned academics from Keio University and University College London will be presenting the latest advances in neuroscience research in this afternoon symposium. Attendance is free of charge.
02 Aug 2007
The Conference, themed Overcoming An Old Scourge With A New Face (HIV/TB Co-Infection) aims at highlighting the challenge of HIV/TB co-infection, and at the same time emphasising on the other core challenges of the TB control.
12 Jul 2007
A five-day congress with plenary sessions on the latest developments in the fields of bronchology and thoracoscopy, and educational thematic sessions.
23 Jan 2008
The aim of the Symposium is to stage a forum in which researchers and scientists working in the field of avian influenza can exchange information and experience, which could possibly lead to future research collaborations.
17 May 2007
The conference will highlight issues on Chinese regulation and infrastructure for clinical trials, Current status of regulation and clinical trials in Asian countries and Asian development strategy and clinical operations
31 May 2007
Paris, France - This international event wil gather veterinarians, medical experts, government officials, scientists and economic decision-makers from countries all over the world touched by the spread of Avian Influenza.
21 Apr 2007
The Forum will offer a unique opportunity for leading regional and international experts to come together with a unified goal of addressing the specific issues surrounding the provision, and future needs, of effective cancer care in Asia. The Forum will focus on the ten most prevalent cancers in Asia-Pacific.
17 Mar 2007
Sagar (Madhya Pradesh), India - The objective of the proposed seminar is to disseminate and exchange the state-of-the-art knowledge in the field of pharmaceutical nanotechnology as a mean of treating the diseases through most efficient mode of controlled and targeted drug delivery.
14 Mar 2007
The International Conference in Quantum Bio-Informatics Center (QBIC) will be held at Noda Campus of Tokyo University of Science from March 14 to March 17, 2007
20 Mar 2007
Uttar Pradesh, India - According to WHO reports, the international market of herbal products is estimated to be US 62 billions. But there's a relatively lower share of medicinal and aromatic plants in agriculture systems. This seminar explores the reasons and finds solutions.
07 Mar 2007
Bangkok, Thailand - This event is held in conjunction with the 5th Southeast Asia Soyfood Seminar and Tradeshow.
09 Sep 2007
Taipei, Taiwan - The theme of the congress is "Diet, Nutrition and Optimal Health: From Food Supply to Nutrigenomics."
16 Apr 2007
Istanbul, Turkey - The theme of the conference is "Consequences and control of micronutrient deficiencies - Science, Policy and Programs - Defining the Issues
29 Mar 2007
The theme of the conference is "Current Concerns in Adolescent Nutrition". Topics that will be given particular attention include health problems affecting adolescent (e.g. obesity, diabetes, anemia), eating habits and sports nutrition.
01 May 2007
Nanjing, China - The workshop aims to be a highly communicative meeting place for researchers working on a wide range of biomedical topics.
05 Mar 2007
Kuala Lumpur, Malaysia - Despite some progress made in tackling the traditional OHS problems, the accident and fatality rate due to occupation is still high especially in developing countries. It is estimated that the risk of accident in developing countries is 10 to 20 times higher than the industrialised countries
08 Feb 2007
Bangkok, Thailand - Medical tourism is bringing a new breed of travellers. They have particular needs, they are going to these locations for a specific reason, and reports are showing that their daily spend is more than double that of other tourists.
30 Nov 2007
Unsustainable living, climate change and disassociation from nature are beginning to take their toll and disastrous repercussions for human health and survival are anticipated by researchers across the globe. The transdisciplinary nature of ecohealth is an innovative way of addressing these issues.

Researchers

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Giants in history

Henriette Bui Quang Chieu (1906 – 2012) was inspired to follow in her brother’s footsteps and become a doctor after losing her mother to tuberculosis. She studied in France and became the first Vietnamese woman to receive a medical degree. Upon her return to Vietnam, Bui was appointed head of the Department of Midwifery at Cho Lon Hospital in Ho Chi Minh City. A pioneer in gynaecology, she applied acupuncture techniques that she had learned in Japan to obstetrics. As Vietnam was still a French colony, Bui also lobbied for the rights of Vietnamese doctors, nurses, and patients.
Japanese biochemist Akira Endo (1933 – 2024) discovered the first statin, called mevastatin, which lowered cholesterol levels in the blood by inhibiting a key enzyme in the cholesterol biosynthesis pathway. His work laid the foundation for the development of statins to help patients lower their blood cholesterol levels and reduce their risk of heart disease or stroke.
Filipina paediatrician and scientist Perla Santos-Ocampo (25 July 1931 – 29 June 2012) made important contributions to treatments and policies that curbed debilitating and sometimes deadly diarrhoea-related diseases and malnutrition in children.
Singaporean physician Oon Chiew Seng (1916 – 31 March 2022) advanced dementia care and research in Singapore, and co-founded the Apex Harmony Lodge, the nation’s first nursing home for residents with dementia.
Vietnamese surgeon Tôn Thất Tùng (10 May 1912 – 7 May 1982) developed a pioneering technique that reduced the risks and mortality rate of liver operations.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
Maggie Lim (5 January 1913 – November 1995) was a Singaporean physician who promoted family planning and expanded the access to clinics to improve the quality of life for mothers and children in Singapore’s early days.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
The founder of the Adyar Cancer Institute in India, Muthulakshmi Reddy (30 July 1886 – 22 July 1968), fought to uplift women and girls from impoverished situations.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health. In relation to botany, she uncovered the means by which asexually-reproducing plants evolve into new species.
The first Thai woman to receive a degree in medicine, Margaret Lin Xavier (29 May 1898 – 6 December 1932), is best remembered for her compassion towards her less privileged patients.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
In 1915, Koichi Ichikawa along with pathologist Katsusaburo Yamagiwa became the first to prove that chronic exposure to chemicals can cause cancer.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Ground-breaking cancer researcher Kamal Jayasing Ranadive (8 November 1917 – 11 April 2001) advanced the understanding of the causes of leukaemia, breast cancer and oesophageal cancer through the use of animal models. She was also among the first to recognise how susceptibility to cancer is linked to tumour-causing interactions between hormones and viruses.
The research of Filipino pharmaceutical chemist Luz Oliveros-Belardo (3 November 1906 – 12 December 1999) focussed on essential oils and other chemicals derived from native Philippine plants.
Thai physician and conservationist Boonsong Lekagul (1907 – 1992) made major contributions to the preservation of his country’s wildlife.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Korean parasitologist Seung-Yull Cho (16 November 1943 – 27 January 2019) is remembered largely for his pioneering works to control infections caused by helminthic parasites and his contribution to journal publishing.
Fe Villanueva del Mundo (27 November 1911 – 6 August 2011) was a Filipina paediatrician who founded the Philippines’ first paediatric hospital.
After witnessing death and suffering as a youth in his home village during World War II, Nguyễn Tài Thu (6 April 1931 – 14 February 2021) set his sights on alleviating pain by becoming a doctor. After studying Traditional Chinese Medicine in China in the 1950s, Thu returned to Vietnam to serve in military hospitals. Eventually, he became the country’s foremost practitioner of acupuncture, a technique he first learned by inserting needles into himself.
Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
Wu Lien-teh (10 March 1879 – 21 January 1960) was a Malaysian-born doctor who invented a mask that effectively suppressed disease transmission. Winning the prestigious Queen’s Scholarship enabled Wu to become the first Chinese student to study medicine at the University of Cambridge.
David T. Wong (born 1936) is a Hong Kong-born American neuroscientist who is best known for discovering the antidepressant drug fluoxetine, better known as Prozac.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Tu Youyou (born 30 December 1930) is a Chinese pharmaceutical scientist who was awarded the 2015 Nobel Prize in Physiology or Medicine for her work on extracting artemisin from sweet wormwood to treat malaria.
Chika Kuroda (24 March 1884 – 8 November 1968) was a Japanese chemist whose research focussed on the structures of natural pigments.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Syed Qasim Mehdi (13 February 1941 – 28 September 2016) was a Pakistani molecular biologist who was a founding member of the Human Genome Diversity Project (HGDP), which assessed human diversity by studying human migration, mutation rates, relationships between different populations, genes involved in height and selective pressure.
Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine. She discovered that gout, a condition characterized by the painful inflammation of joints, was caused by elevated levels of uric acid in the bloodstream.
Min Chueh Chang (10 October 1908 – 5 June 1991) was a Chinese-American biologist who studied fertilization in mammalian reproduction.
A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
Ogino Ginko (3 March 1851 – 23 June 1913) was the first registered female doctor to practise modern medicine in Japan.
Esther Park (1877-1910), born Kim Jeom-dong, was the first female Korean physician to practise modern medicine in Korea and trained the first generation of Korean female doctors.