Medicine

A newly designed model system simulates how viruses exit cells, offering potential advancements in targeted drug delivery and biotechnology.

A new treatment with iron nanoparticles and nitric oxide gas shows promise in destroying oral cancer cells.

The study identifies gut microbes and genes that regulate TMAO production from L-carnitine, offering potential for personalized nutrition strategies.

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and Duke-NUS Medical School have provided compelling evidence that short-course antibiotic treatments can be a game-changer in tackling ventilator-associated pneumonia (VAP), a serious infection common in critically ill patients.

Lingnan University’s School of Interdisciplinary Studies (SIS) and the Center of International Innovation for Technology and Science (CIITS), signed a Cooperation Framework Agreement at the InnoBay · Future Industry Forum——Shenzhen-Hong Kong Exchange Session (CIITS) in the Shenzhen Park of Hetao Shenzhen-Hong Kong Science and Technology Innovation Cooperation Zone yesterday (16 January). Prof Chen Xi, Dean of SIS, and Mr Liu Renchen, Director of the CIITS, signed on behalf of both parties, injecting new momentum into promoting scientific and technological innovation cooperation.

Intermittent fasting, especially alternate-day fasting, provides an effective alternative to continuous energy restriction for improving metabolic health.

A research team proposes a method to assess cancer patients for their likelihood to either respond to treatment or relapse.

Crossing the uncanny valley, Batteries that don’t explode, Tiny climate change fighters, Liver-friendly mushroom & Foetal defence. Read all in the latest Editor's Choice.

Gut microbe isolated from infertile women disrupts progesterone metabolism, lowering progesterone levels and impairing ovarian follicular development.

Ateneo researchers are looking to turn milkfish skin, a common waste byproduct of the Philippine fishing industry, into an invaluable medical resource.

New formula for hyperfiltration and glomerular filtration rate takes natural decline into account

Early administration of AHCC at the stage of hepatitis might hold possibility of preventing onset of cirrhosis

Use of automated system in upper extremity paralysis care proves beneficial for patients and medical staff

Researchers from Osaka University have revealed some of the precise mechanisms by which erroneous cells are recognized, marked for removal, and eliminated via apoptosis in developing zebrafish. Notably, they found that the protein Foxo3 may be a universal marker of cell competition in zebrafish and mice. These findings have important implications for congenital disorders, cancer, and aging, and may lead to novel treatments.

Utilizing pericellular and intracellular controlled-release of carboplatin to precisely synergize with reduced-dose radiotherapy, aiming to eradicate malignant gliomas.

Enhanced pedicled latissimus dorsi flap technique achieves 100% success rate in high-risk head and neck reconstruction

New research suggesting a link between motor protein Kif23 and microcephaly may be the key to developing more effective treatments for this condition.

The hydrogen atoms of [4Fe-4S] type ferredoxin, one of the electron carriers, have been visualized and both experiments and calculations have revealed the mechanisms that control the redox potential. Aspartic acid (Asp64) located a distance away from the [4Fe-4S] cluster of ferredoxin, was found to be the control switch, an evolutionarily conserved mechanism.

Researchers at Osaka University have identified ARMC5 as a key regulator of fatty acid balance in adipose tissue. ARMC5 degrades non-SCAP-bound SREBP1, activating it to regulate stearoyl-CoA desaturase (SCD), an enzyme essential for fatty acid desaturation. This discovery opens avenues for developing drugs targeting ARMC5 to manage fatty acid levels and improve health outcomes.

Although crackles have long been regarded as a hallmark finding in physical examinations, this study revealed their unreliability not only among human physicians but also in artificial intelligence systems.

Lingnan University will confer honorary doctoral degrees on two leading professors in recognition of their outstanding achievements and valuable contributions to humanity. They are renowned mathematician Prof Yau Shing-tung and distinguished structural biologist Prof Nieng Yan.

A new simulator gives nursing students hands-on practice with vital procedures like mechanical ventilation and tracheal suctioning in children.

Conversely, role in controlling cell proliferation might lead to novel tumor therapies in humans

International integration of drug-drug interaction information through mapping of Japanese and international drug codes

SGLT2 inhibitor canagliflozin helps oxygenate kidneys while causing glucose removal through urine

Born from 1995 to 2012, Gen Z is motivated by financial pragmatism, personal achievement, and values-driven work distinctive from older generations.

Researchers at Helmholtz Munich and Tohoku University have discovered that PRDX6, a selenium carrier protein, plays a key role in regulating ferroptosis, a form of oxidative cell death. This finding could lead to new approaches in treating cancer by increasing ferroptosis sensitivity and in neurodegenerative diseases by protecting neurons. The study, published in Molecular Cell, highlights PRDX6’s potential as a therapeutic target for both conditions.

• This breakthrough test requires only a small blood sample to track modified T cells in patients over time, ensuring therapies remain effective. • This plug-and-play approach is set to accelerate the development of more T-cell-based therapies and vaccines.

Osaka University researchers elucidated the molecular details of how Drosophila larval epidermal cells (LECs) undergo cell death in a controlled manner to regulate epithelial tissue remodeling. Specifically, lower activation of the epidermal growth factor receptor (EGFR) signaling pathway occurs following reduced endocytosis. Decreased EGFR pathway activity allows LECs to switch from undergoing single-cell apoptosis to more widespread cell death in clusters. This supports faster LEC elimination and allows for proper tissue remodeling.

King of nanomaterials, Old but new, Probing stardust properties, Two-in-one, The good grain & Brain-inspired electronic skin. Read all in the latest Editor's Choice.