Dr. Matthew Tay

Dr. Tay has researched antibodies and diseases like malaria and SARS-CoV-2 at A*STAR. His focus is on discovering methods for developing antibodies that can be used in therapies against multidrug-resistant pathogens.

Dr. Tay has researched antibodies and diseases like malaria and SARS-CoV-2 at A*STAR, first at the Singapore Immunology Network (SIgN) and later at the A*STAR Infectious Diseases Labs (A*STAR ID Labs). His focus is on discovering methods for developing antibodies against multidrug-resistant pathogens.

He studies the antimicrobial functions of antibodies to help improve the effectiveness of antibody-based diagnostics and therapeutics against both current and emerging pathogens. His lab investigates how each antibody‚Äôs antimicrobial functions relate to its mode of interaction with its target, allowing the discovery of potential targets critical to an effective vaccine. 

Selected publications

  • Google Scholar
  • Tay M.Z. et al. Decreased memory B cell frequencies in COVID-19 delta variant vaccine breakthrough infection. EMBO Mol Med 14, (2022) DOI: 10.15252/emmm.202115227
  • Tay M.Z. et al. Monkeypox: disease epidemiology, host immunity and clinical interventions. Nat Rev Immunol Vol 22, 597-613 (2022) DOI: 10.1038/s41577-022-00775-4
Matthew Tay
Singapore
Role: 
Investigator
Department: 
Antimicrobial Biologics Laboratory
Language: 
English
Academic disciplines: