Diseases

News

23 Sep 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the effects of extreme weather becoming more likely due to climate change and leading to sinking cities, putting googly eyes on cars that help pedestrian safety, and how many ants there are on Earth.
22 Sep 2022
A pathway that malfunctions in advanced non-alcoholic fatty liver disease could be fixed with the aid of spermidine, a compound naturally found in bodily cells and certain whole foods.
22 Sep 2022
Scientists have uncovered how Coxsackievirus B3, the most common cause for viral heart inflammation, takes advantage of a specific heart sensor to trigger chronic inflammation that can lead to heart failure.
15 Sep 2022
Cellular structures called mitochondria depend on microproteins to assist and control the assembly of a protein chain that extracts energy from nutrients, according to a new study by scientists in Singapore.
13 Sep 2022
The Memorandum of Understanding signed between The Ngee Ann Kongsi and Duke-NUS Medical School emphasises the need for more research as treatment and prevention options are currently limited for conditions such as Parkinson’s disease.
09 Sep 2022
While the primary site of SARS-CoV-2 infection is in the nose, most antiviral immunity studies have been performed with peripheral blood. T-cell analysis of nasal swab samples suggests getting infected with SARS-CoV-2 following vaccination could confer potentially more robust, nasal-based immunity.
02 Sep 2022
Even a small temperature drop in the tropical climate of Singapore increases the risk of heart attack among people aged 65 and above, say researchers from Duke-NUS Medical School, Singapore’s National Environment Agency and collaborators.
01 Sep 2022
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school.
Editor's Choice
26 Aug 2022
Researchers have made perovskite solar cells more efficient and stable, A new cause of Parkinson's related cell death, Hibernating superpower is in the blood, Common mechanism for cancer and atherosclerosis, COVID-19 antibody skin-based test. Read all in the August's Editor's Choice plus an Interview with Prof Sutee Yoksan on The story behind the new dengue vaccine & this month's Asia Research News 2022 magazine pick - The evolutionary history of puddle frogs.
24 Aug 2022
A study led by researchers from Hong Kong Baptist University (HKBU) has demonstrated that a multifunctional organic compound named F-SLOH has the potential to treat Alzheimer’s disease (AD) at an early stage. The team found that it can inhibit the aggregation of amyloid-beta (Aβ), and reduce the hyperphosphorylation of tau proteins and neuroinflammation in the brain to improve the pathological features of AD. The findings have been published in the international academic journal Redox Biology.
23 Aug 2022
Takeda’s tetravalent dengue vaccine (TAK-003) is now the only dengue vaccine approved in Indonesia for use regardless of previous dengue exposure and without the need for pre-vaccination testing. This approval marks Takeda’s first marketed vaccine outside of Japan.
IMAGE
23 Aug 2022
Two new approaches could help scientists use existing sequencing technology to better-distinguish RNA changes that affect how their genetic code is read.
05 Aug 2022
Scientists at Duke-NUS Medical School, Singapore, have found that elevated blood levels of an amino acid called homocysteine correlate strongly with the severity of an advanced form of non-alcoholic fatty liver disease. They also found vitamin B12 and folic acid could potentially prevent and/or delay disease progression.
Oxidized-LDL accumulates (left column) in malignant tumors (bottom) much more than in non-malignant ones (top). This attracts neutrophils (right column, red) to malignant tumors (bottom), but not to non-malignant ones.
25 Jul 2022
A key molecule for cancer metastasis has been identified as a molecule already known for its involvement in cardiovascular disease, suggesting a possible treatment approach for both diseases simultaneously.
22 Jul 2022
The World Health Organization (WHO) welcomes the launch by Gavi, the Vaccine Alliance, of the landmark opportunity for countries to apply for funding to introduce, or further roll-out, the RTS,S/AS01 (RTS,S) malaria vaccine.
When mice that exhibit SLE-like symptoms are subjected to sleep deprivation stress, their neurons exhibit abnormal growth (left). When IL12 and 23 are blocked, the abnormal growth is reversed (right; Nobuya Abe, et al. Annals of the Rheumatic Diseases. July 11, 2022).
11 Jul 2022
A novel molecular pathway involving cell signalling proteins in the brain may explain how stress affects neuropsychiatric lupus with diffuse neuropsychological manifestations.
08 Jul 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are zero-waste poultry processing that can boost lab-grown meat, residential facilities made for low-gravity environments, and new methods of cloning cells.
01 Jul 2022
Specialised physician training, nurse-led motivational conversations and follow-up with patients, and subsidy on combination medication significantly lowered BP among patients with uncontrolled hypertension, according to findings from Singapore.
01 Jul 2022
Researchers report a new, minimally invasive, antibody-based detection method for SARS-CoV-2 that could lead to the blood sample-free detection of many diseases
29 Jun 2022
The skin’s top layer contains a diverse set of hundreds of lipid molecules called ceramides with varying chain lengths that play a vital role in its barrier function.
13 Jun 2022
Themed “Roll Back Dengue” and organised as a hybrid event, the three-day summit will congregate dengue community including over 200 clinicians, researchers, government public health leaders and policymakers across Asia
Mr Heng Swee Keat speaks at the launch of the Duke-NUS Centre for Outbreak Preparedness
11 Jun 2022
Duke-NUS is working with the Bill and Melinda Gates Foundation to develop the Asia Pathogen Genomics Initiative (APGI) to improve regional genomic surveillance and sequencing capacity. New Centre for Outbreak Preparedness will support APGI and work closely with national and global partners to enhance regional capacity to predict, prepare and respond to future health threats.
10 Jun 2022
SINGAPORE, June 9, 2022– Takeda Pharmaceutical Company Limited (“Takeda”) today announced that its dengue vaccine candidate, TAK-003, prevented 61% of symptomatic dengue cases and 84% of hospitalised cases with no important safety risks identified in the overall population.
UHRF1 controls DNA methylation of synovial fibroblasts in RA patients.
07 Jun 2022
Potential of a novel therapeutic strategy for rheumatoid arthritis by UHRF1 stabilization We identified an epigenetic regulator UHRF1 that suppresses various pathogeneses in rheumatoid arthritis. The UHRF1 expression level in synovium showed a negative correlation with the severity of pathogenesis in patients with rheumatoid arthritis and mouse arthritis models. In addition, stabilization of the UHRF1 expression achieved improvement of the arthritis pathology. Our results indicate that the stabilization of the UHRF1 protein is a potential therapeutic strategy for rheumatoid arthritis patients.
06 Jun 2022
In order to quickly detect the presence of the influenza A virus, researchers developed a fluorogenic probe that could bind to the promoter region. A fluorogenic probe uses tiny molecules called fluorophores that emit light when a specific target is present.
02 Jun 2022
Giants in History: Known for her pioneering contributions to bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is considered India’s most prolific chemist.
23 May 2022
The antibiotic rifampicin is shown as a potential medicine for preventing Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal dementia (FTD).
Rheumatoid Arthritis (CC BY-NC 2.0 Leides Moura)
17 May 2022
Adenosine triphosphate (ATP) secreted from sensory neuron-interneuron crosstalk is key to the spreading of inflammation across joints, acting as a neurotransmitter and inflammation enhancer.
Kamal Jayasing Ranadive
05 May 2022
Giants in History: Ground-breaking cancer researcher Kamal Jayasing Ranadive (8 November 1917 – 11 April 2001) advanced the understanding of the causes of leukaemia, breast cancer and oesophageal cancer through the use of animal models.
Asia Research News Editor's Choice
14 Apr 2022
Bacteria hitchhike on red blood cells, New model simulates effects of exercise on muscles, Argon found in air of ancient atmosphere and Revealing emergent elastic fields of chiral crystals. Read all in the April Editor's Choice and this month's Asia Research News 2022 magazine pick - Asia's race to outsmart antimicrobial resistance.

Events

20 Jun 2022
This event, held alongside the COVID-19 International Innovation Awards from 20 to 24 June, will bring forth and showcase innovations that are driving improvements and transforming the healthcare industry.
20 Jun 2022
COVID-19 International Innovation Awards (a virtual event), part of MTE 2022 year-long innovation awards programme, is scheduled to return on 20-24 June 2022. The awards are created to acknowledge and celebrate all innovations in response to COVID-19.
07 Nov 2022
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
25 Jan 2022
With a brand-new focus, join us to explore Asia Healthcare Analytics Summit happening LIVE on 25 & 26 January 2022 via Hopin platform with 30+ Inspiring speakers, 100+ Virtual attendees, 4+ Networking session, 3+ Panel discussions of healthcare experts globally participating in this summit.
01 Nov 2021
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
07 Oct 2021
The National Healthcare Group (NHG) is proud to present the 19th Edition of the Singapore Health & Biomedical Congress (SHBC).
23 Nov 2020
Global health emergencies look set to be a part of our lives. What awaits us in 2021 and what lessons can we draw from COVID-19 coverage? How can we support newsrooms and journalists for more informed and impactful journalism about global scientific, technical and human challenges? What role does journalism play in seeking solutions for a better world that is both healthy, and sustainable?
02 Nov 2020
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
01 Oct 2020
The 6th annual RNA Biology Symposium jointly organized by the RNA Biology Centre of CSI Singapore (NUS), Skin Research Institute of Singapore (A*STAR), Duke-NUS Medical School, School of Biological Sciences (NTU) and Singapore-MIT Alliance for Research and Technology (SMART)
The Khwarizmi International Award (KIA) acknowledges the efforts made by researchers, innovators and inventors from across the globe and to appreciate their high quality research work and contributions to different fields of science and technology.
26 Jun 2020
Flattening the Curve with Digital Health: Episode 7 - Australia
18 Jun 2020
Flattening the Curve with Digital Health: Episode 6 - Thailand
10 Jun 2020
Flattening the Curve with Digital Health: Episode 5 - Japan
04 Jun 2020
Flattening the Curve with Digital Health; Episode 4 - Malaysia
21 May 2020
Flattening the Curve with Digial Health - Episode 2: Singapore
28 May 2020
Flattening the Curve with Digital Health: Episode 3 - South Korea
14 May 2020
Flattening the Curve with Digital Health - Episode 1 - China
04 Nov 2019
We bring together distinguished cancer researchers with complementary knowledge and expertise from across the globe for the exchange of ideas and information.
09 Sep 2019
This conference brings together a focus on technology development as well as applications for biomarker analysis in cancer, cardiovascular disease and other disease classes.

Researchers

Hong Kong Baptist University (HKBU)
Prof. Cai Zongwei is now the Chair Professor of Chemistry in the Department of Chemistry and Director of both State Key Laboratory of Environmental and Biological Analysis as well as Dioxin Laboratory, Hong Kong Baptist University.
The Asian Institute of Technology
Dong currently works at the Asian Institute of Technology. He does research in Aquaculture, Pathology, Infectious Diseases, and Aquatic Bioscience.
Suraj Bhattarai is a global health specialist and tropical medicine physician with research interests in infectious disease epidemiology and surveillance, health systems, and urban health. He is a co-founder and research fellow at the Global Institute for Interdisciplinary Studies, a Kathmandu-based academic institute that promotes and conducts interdisciplinary research. He is a member of Global Young Academy and an Alumni steering committee member of IAP-Young Physician Leaders Programme. He obtained medical training in Nepal and masters in Tropical Medicine & International Health from the LSHTM, UK.
I am a Health Economist/Researcher, working with UN agencies in the development of policy documents for developing countries including Nepal, Ethiopia and Pakistan.
City University of Hong Kong (CityU)
Dr. Brian Kot Chin Wing
Dr Brian Kot is a registered diagnostic radiographer and veterinary imaging researcher in the City University of Hong Kong.
Osaka City University
Takashi Hashimoto's major expertise is clinical and basic research for both autoimmune bullous diseases and hereditary skin diseases.
Universiti Teknologi MARA (UiTM)
Department of Microbiology / Biomolecular Sciences Universiti Teknologi MARA Malaysia
Osaka City University
Dr. Akira Kaneko
Akira Kaneko was appointed as Professor of Parasitology of Osaka City University in 2010. Since then, he has conducted global health research with a particular focus on malaria elimination on islands in Vanuatu, Oceania and Lake Victoria, Kenya.
Duke-NUS Medical School
Prof. Patrick Tan's research focuses on developing genomic approaches to unlock the molecular and clinical diversity of gastric cancer (aka stomach cancer)- a leading cause of global cancer mortality.
Daegu Gyeongbuk Institute of Science and Technology (DGIST)
Picture of Prof. Jinsoo Seo
Prof. Jinsoo Seo's research focuses on mechanisms of cellular dysfunction and cognitive decline in aging brain, genetic risk factors for neurodegeneration as well as the effect of environmental factors and lifestyle on Alzheimer's disease.
Dr. Indika Neluwa-Liyanage is a lecturer in Biochemistry at the Faculty of Medical Sciences of University of Sri Jayewardenepura. His research focuses on the metabolic alterations underlying autism spectrum disorders and inherited metabolic disorders.
Dr. Mohammed N. Abdulrazaq is currently an Assoc. Prof. at Department of Engineering & Technology, Management & Science University (MSU), Malaysia.
Universiti Malaysia Sabah
Dr. Connie Cassy Ompok is an early childhood education expert and a Senior Lecturer at the Faculty of Psychology and Education, Universiti Malaysia Sabah. She Started her career in Early Childhood Education as a preschool teacher (2004-2007), a lecturer in early childhood education at the Malaysian Institute of Teacher Education (2008-2016) before serving as a Senior Lecturer in Early Childhood Education at UMS (2016 until now).
Currently a research assistant in the laboratory of green energy in Zhejiang University of Technology.
Universiti Malaysia Sarawak
Dr Paul Cliff Simon Divis is the director of Malaria Research Centre at Universiti Malaysia Sarawak (UNIMAS).
I do research on dysmennorrhoea and gender-based violence. I am a pioneer in registered clinical trials on indigenous and Ayurveda medicines in Sri Lanka. I have approval for a herbal preparation, for COVID patients.
I am an Assistant Professor in Health Services Policy and Management at the University of South Carolina Arnold School of Public Health, US. As a health services researcher and a rural health advocate, I am driven to advance rural health equity via productive, insightful research collaborations. My work applies global and hyper-local perspectives (rural-urban, county-level, state-level variations) building statistical models to examine rural healthcare delivery on outcomes, access, and welfare of women.
Duke-NUS Medical School
Professor Linfa Wang is a Professor with the Emerging Infectious Diseases Programme at Duke-NUS Medical School, Singapore.
Associate Professor Sophia Archuleta is the Head and Senior Consultant of the Division of Infectious Diseases at the National University Hospital, Singapore.
Mangala Gunatilake is a veterinarian and professor at the Department of Physiology, Faculty of Medicine, University of Colombo, Sri Lanka.
Nimanthi Jayathilaka is a professor at the Department of Chemistry, University of Kelaniya, Sri Lanka.
Hira Khalid is an associate professor at the Department of Chemistry of Forman Christian College University, Lahore, Pakistan.
Universiti Teknologi MARA (UiTM)
Dr Heo is currently a senior lecturer at the Department of Microbiology and Parasitology, Faculty of Medicine, Universiti Teknologi MARA, Malaysia.
Duke-NUS Medical School
Dr. Tazeen Jafar is a global health leader and expert with a focus on implementation research in hypertension, cardiovascular disease, and chronic kidney disease.
Hokkaido University
Postdoctoral fellow, Faculty of Veterinary Medicine, Hokkaido University, Japan
Duke-NUS Medical School
Dr Danielle Anderson is the Scientific Director of the Duke-NUS Medical School ABSL3 laboratory.
Tohoku University
A professor at the Bone Regenerative Engineering Laboratory, Regenerative and Biomedical Engineering Division, Graduate School of Biomedical Engineering, Tohoku University, Japan
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
My research background covers multidisciplinary fields such as Pharmaceutics, Cancer Nanomedicine, Bioengineering and Organ-on-a-chip platforms. My current research focuses on the development of dynamic biological barriers on a chip such as blinking human cornea on a chip.
Hokkaido University
Hidemitsu Kitamura is an associate professor at the Section of Disease Control, the Institute for Genetic Medicine, Hokkaido University, Japan.
Professor Ahmed Al-Haddad, M.Sc., Ph.D. (Germany) is currently Professor of Microbiology and Medical Microbiology at College of Medicine and Health Sciences, Hadhramout University-Yemen. He is the Founding-Dean of the first Faculty of Nursing in Yemen. He has over fifteen years of research and teaching experience in various domains of life sciences. Al-Haddad has published many peer reviewed articles and conference papers in the areas of molecular biology, microbiology and antibiotics in National and International journals. He is reviewer in different national and international Scientific Journals such as Annals of Clinical Microbiology and Antimicrobials, Journal of Microbiology and Antimicrobials, Sultan Qaboos University Medical Journal, British Biotechnology Journal. He is a member of various national and international scientific organizations.