Diseases

News

02 Feb 2023
Blocking an immune-regulating protein reverses the damage caused by acute and chronic kidney disease, a preclinical study suggests.
The fluorescent blinking of cyanine dye (Alexa Fluor 647, pink star) bound to RNA changes depending on the structure of the RNA. When the RNA is folded like a hairpin, the fluorescent blinking is fast, and when the RNA switches to a G-quadruplex, the blinking is slow (Akira Kitamura).
02 Feb 2023
A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.
Asia Research News: Editor's choice
20 Jan 2023
Overeating mechanism: why "eating just one chip"🍟 is impossible, Measuring hidden energy of gamma-ray bursts, Marine species that can adapt to ocean acidification & A rough start can lead to a strong bond, Read all in our first Editor's Choice of 2023. Plus our interview on what dengue vaccine approval in EU💉means for global dengue protection.
When the H5N1 HPAI virus (orange) affected a flock of crows in a public garden, it caused a mass die-off of crows. An Ezo red fox and a Japanese raccoon dog were also infected by the H5N1 HPAI virus, the former likely by consuming corpses of the crows, and the latter due to close contact with crow corpses (Illustration: Takahiro Hiono).
05 Jan 2023
Researchers at Hokkaido University have revealed the effects of high pathogenicity avian influenza virus infection on an Ezo red fox and a Japanese raccoon dog, linking their infection to a recorded die-off of crows.
04 Jan 2023
A research study led by scientists from the School of Chinese Medicine (SCM) at Hong Kong Baptist University (HKBU) has shown for the first time that the human gut bacterium Ruminococcus gnavus is a major trigger factor of diarrhoea-predominant irritable bowel syndrome (IBS-D). Based on this discovery, a new therapeutic target for the disease’s treatment was identified. The study also found that low-protein food items such as fresh fruits, vegetables and bread may help reduce the gut motility in IBS-D.
23 Dec 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are how a wasp uses its genitals to defend itself, a compound commonly found in mushrooms that could delay cognitive decline, and sunshine as a cure for myopia.
15 Dec 2022
Understanding how bats tolerate viral infections, Material separates water from...water, The virtual sense of touch polished to next level and COVID-19 negatively impacted early-careers and female researchers. Read all in the December's Editor's Choice.
12 Dec 2022
Revelations about the mechanisms of two key proteins which maintain the asymmetric distribution of cholesterol within the cell membrane could help understand and treat diseases linked to its imbalance
09 Dec 2022
Silencing the gene, called WWP2, in patients in the early stages of cardiomyopathy could delay progression to heart failure by controlling immune cell infiltration and activation, and halting the formation of excessive scar tissue, preclinical data suggest.
09 Dec 2022
− The European Commission Approved QDENGA (TAK-003) for Use in Individuals Four Years of Age and Older [i] − QDENGA Becomes the Only Dengue Vaccine Approved in the EU for Use in Individuals Regardless of Previous Dengue Exposure [i]
Flossie Wong-Staal
08 Dec 2022
Giants in History: Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
07 Dec 2022
First-in-the-world high-resolution imaging allows scientists to study the dengue protein in greater detail to yield valuable insights.
24 Nov 2022
Understanding how bats tolerate viral infections without developing symptoms may lead to better ways of combatting human disease.
18 Nov 2022
Exploring virtual human-agent relationships, A fly protein gives clue for human cancers, Rare earth elements formed in neutron star mergers 💥, One-stop process for hydrogen production. Read all in the November's Editor's Choice plus Upcoming event K4DM KNOWLEDGE MARKETPLACE – Bangkok 2022: Exchanging Ideas for a Democratic Myanmar.
10 Nov 2022
Giants in History: Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
04 Nov 2022
Research in Singapore confirms a link between tiny particulates in air pollution and sudden cardiac arrests in the general population.
01 Nov 2022
Triple-negative breast cancer (TNBC) tumors gain immunosuppression and chemoresistance through interactions between interleukin 34 and myeloid-derived suppressor cells, researchers find.
31 Oct 2022
Call To Action urges G20 member countries and partners to mobilize adequate resources to close the TB funding gap and save lives.
25 Oct 2022
Research led by the School of Chinese Medicine at Hong Kong Baptist University (HKBU) has identified cryptotanshinone, a compound extracted from the Chinese herbal medicine Salvia miltiorrhiza, with the potential for the treatment and prevention of gastric cancer associated with bile reflux. The researchers unveiled the mechanism of how bile reflux induces gastritis and gastric cancer. They explained that refluxed bile acids (BAs) lead to the proliferation of pro-inflammation bacteria that promote gastric carcinogenesis, the formation of cancer.
25 Oct 2022
Small neighboring galaxy filled with dark matter detected with gamma rays, How a virus induces heart inflammation, Shedding light on the happy hormone, Microfossils may hold key evolution clues. Read all in the October's Editor's Choice plus Upcoming event KNOWLEDGE MARKETPLACE – Bangkok 2022: Exchanging of ideas for a Democratic Myanmar.
24 Oct 2022
Investigations in Japan have uncovered some molecular mechanisms behind mitochondrial dysfunction in chronic heart failure.
20 Oct 2022
Giants in History: Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Japanese Wild Boar (KENPEI, CC BY-SA 3.0/Wikimedia Commons)
18 Oct 2022
Researchers develop a ground-breaking model to estimate bait vaccination effectiveness in wild animals based on the proportion of immunized animals in a population and the number of vaccine applications.
14 Oct 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are shrinking mangroves, a wind harvester that can generate electricity using a breeze, and a new supercontinent 300 million years from now.
13 Oct 2022
Giants in History: Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
10 Oct 2022
The SARS-CoV-2 Omicron variant escapes the immune response better than its coronavirus ancestors, but has also facilitated our transition to a society that can live with COVID-19.
06 Oct 2022
Giants in History: Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health.
Cancer cell infiltrates the liver through intracellular gaps in LSECs
04 Oct 2022
Metastasis—when cancer spreads to form new tumors—causes approximately 90% of cancer-related deaths. Because metastatic cancer cells circulate in the blood, the liver—which filters the blood—is considered the most vulnerable organ, so treatments that prevent liver metastasis are urgently needed. A team of Osaka Metropolitan University researchers discovered a mechanism that allows metastatic cancer cells to infiltrate the liver, and how that infiltration can be blocked by inhibiting a related protein.
30 Sep 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are an algorithm that can detect epilepsy from brain scans, the first National Robotics Tournament in Vietnam, and how being lonely or depressed can accelerate aging.
Editor's Choice
29 Sep 2022
Linked lanthanides shine light on crystal engineering, New technique reveals hidden genome, Red, white and blue alerts for dangerous bacteria & Windows gain competitive edge over global warming. Read all in the September's Editor's Choice plus this month's Asia Research News 2022 magazine pick - Floating sensors to gather ocean data.

Events

20 Jun 2022
This event, held alongside the COVID-19 International Innovation Awards from 20 to 24 June, will bring forth and showcase innovations that are driving improvements and transforming the healthcare industry.
20 Jun 2022
COVID-19 International Innovation Awards (a virtual event), part of MTE 2022 year-long innovation awards programme, is scheduled to return on 20-24 June 2022. The awards are created to acknowledge and celebrate all innovations in response to COVID-19.
07 Nov 2022
FCS2022 is jointly organized by eight major research institutes in Singapore and includes a line-up of internationally renowned cancer experts. The conference converges the latest cancer discoveries around the world and promises ground-breaking and innovative insights into cancer research.
25 Jan 2022
With a brand-new focus, join us to explore Asia Healthcare Analytics Summit happening LIVE on 25 & 26 January 2022 via Hopin platform with 30+ Inspiring speakers, 100+ Virtual attendees, 4+ Networking session, 3+ Panel discussions of healthcare experts globally participating in this summit.
01 Nov 2021
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
07 Oct 2021
The National Healthcare Group (NHG) is proud to present the 19th Edition of the Singapore Health & Biomedical Congress (SHBC).
23 Nov 2020
Global health emergencies look set to be a part of our lives. What awaits us in 2021 and what lessons can we draw from COVID-19 coverage? How can we support newsrooms and journalists for more informed and impactful journalism about global scientific, technical and human challenges? What role does journalism play in seeking solutions for a better world that is both healthy, and sustainable?
02 Nov 2020
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
01 Oct 2020
The 6th annual RNA Biology Symposium jointly organized by the RNA Biology Centre of CSI Singapore (NUS), Skin Research Institute of Singapore (A*STAR), Duke-NUS Medical School, School of Biological Sciences (NTU) and Singapore-MIT Alliance for Research and Technology (SMART)
The Khwarizmi International Award (KIA) acknowledges the efforts made by researchers, innovators and inventors from across the globe and to appreciate their high quality research work and contributions to different fields of science and technology.
26 Jun 2020
Flattening the Curve with Digital Health: Episode 7 - Australia
18 Jun 2020
Flattening the Curve with Digital Health: Episode 6 - Thailand
10 Jun 2020
Flattening the Curve with Digital Health: Episode 5 - Japan
04 Jun 2020
Flattening the Curve with Digital Health; Episode 4 - Malaysia
21 May 2020
Flattening the Curve with Digial Health - Episode 2: Singapore
28 May 2020
Flattening the Curve with Digital Health: Episode 3 - South Korea
14 May 2020
Flattening the Curve with Digital Health - Episode 1 - China
04 Nov 2019
We bring together distinguished cancer researchers with complementary knowledge and expertise from across the globe for the exchange of ideas and information.
09 Sep 2019
This conference brings together a focus on technology development as well as applications for biomarker analysis in cancer, cardiovascular disease and other disease classes.

Researchers

Mags Crumlish
Dr. Crumlish has researched aquatic microbial diseases, specifically ones that have economic impact in global aquaculture, and potential solutions to such infectious diseases. Her current project seeks to develop vaccines against antimicrobial resistance in aquaculture.
The Agency for Science, Technology and Research (A*STAR)
Matthew Tay
Dr. Tay has researched antibodies and diseases like malaria and SARS-CoV-2 at A*STAR. His focus is on discovering methods for developing antibodies that can be used in therapies against multidrug-resistant pathogens.
Nguyen Huu Nghia
Nguyen Huu Nghia is the Director of the Center for Environment and Disease Monitoring in Aquaculture (CEDMA) at the Research Institute for Aquaculture No.1 (RIA1) under Vietnam’s Ministry of Agriculture and Rural Development. He has co-managed various research efforts in Vietnam aquaculture as well as published recent research into the use of nanobubbles.
Dr. Phan Thi Van
Dr. Van is the Director of the Research Institute for Aquaculture No.1 (RIA1) under Vietnam’s Ministry of Agriculture and Rural Development. She has extensive expertise in aquatic animal health and aquaculture safety management.
City University of Hong Kong (CityU)
Sophie St-Hilaire
Professor St-Hilaire is associate head and professor at the Department of Infectious Diseases and Public Health, City University of Hong Kong (CityU). She has extensively researched fish nutrition and diseases, including treatment efficacy, and has helped investigate fish disease outbreaks.
The Agency for Science, Technology and Research (A*STAR)
Dr. Stefan Oehlers
Dr. Oehlers leads the Bacterial Pathogenesis Laboratory at A*STAR ID Labs, where he and his colleagues focus on identifying molecular bases of mycobacterial disease and, thus, deploy therapies that address antibiotic resistance in mycobacterial infections.
The Agency for Science, Technology and Research (A*STAR)
Professor Yue Wang
Dr. Yue Wang is senior principal investigator at the Antifungal Resistance Laboratory of A*STAR ID Labs, where his body of work focuses on virulence mechanisms of the fungal human pathogen Candida albicans.
The Agency for Science, Technology and Research (A*STAR)
Amit Singhal
Dr. Singhal serves as senior principal investigator at the Bacterial Immunopathology Lab at A*STAR ID Labs in Singapore. His work at A*STAR ID Labs revolves around three main pathogens: Mycobacterium tuberculosis, Gram-negative bacteria and Dengue virus.
National University of Singapore
Dr. Pablo Bifani
Dr. Bifani is an associate professor and research director at the Yong Yoo Lin School of Medicine, National University of Singapore, and a principal investigator at A*STAR ID Labs. He has extensively researched antimicrobial resistance in tuberculosis and malaria.
City University of Hong Kong (CityU)
Jian Yan
Dr. Yan is an assistant professor at the Department of Biomedical Sciences, City University of Hong Kong (CityU). His current research focuses on developing genomic tools to dissect lncRNA function and mechanism in diseases and to identify genetic variations that contribute to disease pathogenesis.
City University of Hong Kong (CityU)
Xin Deng
Dr. Deng is a biomedical scientist with a special interest in bacterial virulence, including gene regulation, signaling pathways, and RNA epigenetics. He has worked on virulence regulation in pathogens to discover new therapies against bacterial infections.
Osaka Metropolitan University
Toshiyuki Ozawa
Dr. Ozawa is a Specially Appointed Professor at the Department of Dermatology, Graduate School of Medicine, Osaka Metropolitan University (formerly Osaka City University). His specialized field is skin malignant tumor and surgery.
Kyoto University
So Iwata
Dr. So Iwata is a Professor at the Graduate School of Medicine Kyoto University and the Group Director of the SACLA Science Research Group, RIKEN SPring-8 Center. He has investigated how specialized membrane channels remove antimicrobial drugs from inside bacterial cells.
Ulsan National Institute of Science and Technology (UNIST)
Robert Mitchell of UNIST
Dr. Mitchell is a professor at the Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST). His primary research interest is the study of bacterial strains that attack and prey on other bacteria, including antimicrobial-resistant pathogens.
Dr. Soojin Jang
Dr. Soojin Jang heads the Antibacterial Resistance Research Laboratory at Institut Pasteur Korea, where her team focuses on discovering new antibacterial agents for “superbugs” or bacteria resistant to most antibiotics.
Hong Kong Baptist University (HKBU)
Prof. Cai Zongwei is now the Chair Professor of Chemistry in the Department of Chemistry and Director of both State Key Laboratory of Environmental and Biological Analysis as well as Dioxin Laboratory, Hong Kong Baptist University.
The Asian Institute of Technology
Dong currently works at the Asian Institute of Technology. He does research in Aquaculture, Pathology, Infectious Diseases, and Aquatic Bioscience.
Suraj Bhattarai
Suraj Bhattarai is a global health specialist and tropical medicine physician with research interests in infectious disease epidemiology and surveillance, health systems, and urban health. He is a co-founder and research fellow at the Global Institute for Interdisciplinary Studies, a Kathmandu-based academic institute that promotes and conducts interdisciplinary research. He is a member of Global Young Academy and an Alumni steering committee member of IAP-Young Physician Leaders Programme. He obtained medical training in Nepal and masters in Tropical Medicine & International Health from the LSHTM, UK.
I am a Health Economist/Researcher, working with UN agencies in the development of policy documents for developing countries including Nepal, Ethiopia and Pakistan.
City University of Hong Kong (CityU)
Dr. Brian Kot Chin Wing
Dr Brian Kot is a registered diagnostic radiographer and veterinary imaging researcher in the City University of Hong Kong.
Osaka City University
Takashi Hashimoto's major expertise is clinical and basic research for both autoimmune bullous diseases and hereditary skin diseases.
Universiti Teknologi MARA (UiTM)
Department of Microbiology / Biomolecular Sciences Universiti Teknologi MARA Malaysia
Osaka City University
Dr. Akira Kaneko
Akira Kaneko was appointed as Professor of Parasitology of Osaka City University in 2010. Since then, he has conducted global health research with a particular focus on malaria elimination on islands in Vanuatu, Oceania and Lake Victoria, Kenya.
Duke-NUS Medical School
Prof. Patrick Tan's research focuses on developing genomic approaches to unlock the molecular and clinical diversity of gastric cancer (aka stomach cancer)- a leading cause of global cancer mortality.
Daegu Gyeongbuk Institute of Science and Technology (DGIST)
Picture of Prof. Jinsoo Seo
Prof. Jinsoo Seo's research focuses on mechanisms of cellular dysfunction and cognitive decline in aging brain, genetic risk factors for neurodegeneration as well as the effect of environmental factors and lifestyle on Alzheimer's disease.
Dr. Indika Neluwa-Liyanage is a lecturer in Biochemistry at the Faculty of Medical Sciences of University of Sri Jayewardenepura. His research focuses on the metabolic alterations underlying autism spectrum disorders and inherited metabolic disorders.
Dr. Mohammed N. Abdulrazaq is currently an Assoc. Prof. at Department of Engineering & Technology, Management & Science University (MSU), Malaysia.
Universiti Malaysia Sabah
Dr. Connie Cassy Ompok is an early childhood education expert and a Senior Lecturer at the Faculty of Psychology and Education, Universiti Malaysia Sabah. She Started her career in Early Childhood Education as a preschool teacher (2004-2007), a lecturer in early childhood education at the Malaysian Institute of Teacher Education (2008-2016) before serving as a Senior Lecturer in Early Childhood Education at UMS (2016 until now).
Currently a research assistant in the laboratory of green energy in Zhejiang University of Technology.
Universiti Malaysia Sarawak
Dr Paul Cliff Simon Divis is the director of Malaria Research Centre at Universiti Malaysia Sarawak (UNIMAS).

Giants in history

Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school. Lim, who helped found the National Zoo of Malaysia and re-establish the Malaysian Nature Society, had a particular interest in researching zoonotic diseases associated with small animals.
A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.