Diseases

Researchers from Duke-NUS Medical School, in collaboration with the Agency for Science, Technology and Research’s Bioinformatics Institute, and the University of Texas Medical Branch, USA, have discovered that the dengue virus changes its shape through mutations in Envelope protein to evade vaccines and therapeutics. The study also gives insights on the types of treatment strategies to use at different stages of infection. This could give rise to new approaches in vaccine development and treatment for dengue disease.

Differential changes in brain functional network connectivity in people with mild cognitive impairment may aid early tracking of Alzheimer’s disease and cerebrovascular disease.

The formation of excess fibrous tissue in the heart, which underlies several heart diseases, could be prevented by inhibiting specific proteins that bind to RNA while its code is being translated.

Successfully identified the existence of two types of 'gastric isthmus stem cells' with different roles and characteristics using a multi-color identification technology. Expects to clarify and treat causes of gastric diseases such as cancer.

New study reveals enzyme plays key role in potentially fatal dengue haemorrhagic fever and shock; suggests clinically approved tryptase inhibitor could be key in future targeted treatment.

UK Research and Innovation and its partners are funding 13 research programs, building collaborations across 10 countries, including Japan, China, Singapore and India.

Scientists have succeeded in reducing levels of the bovine leukemia virus (BLV) in cows with severe infections by combining an immune checkpoint inhibitor and an enzyme inhibitor. The finding could be utilized to control other diseases in cattle, and perhaps in humans someday.

New insight into a protein’s role in regulating tight DNA packing could have implications for combating tumor cell resistance to anti-cancer treatments.

A delegation from Hong Kong Baptist University (HKBU) (HKBU) won a Gold Medal with the Congratulations of Jury, a Gold Medal and a Silver Medal at the 47th International Exhibition of Inventions of Geneva held in Switzerland from 10 to 14 April 2019.

A new model may help clinicians predict the possibility of death from severe dengue infection.

Researchers at Universiti Teknologi MARA reported in the journal Medicine a rare case of hepatocellular carcinoma cells migrating from the liver and settling in the jawbone and shoulder blade of a 61-year-old man.

A new method to diagnose cancer cells inside lymph nodes could allow doctors to treat cancers before they spread around the body.

An annual influenza season forecasting challenge issued by the US Centers for Disease Control provides unique insight into epidemic forecasting, according to a study published in the journal Scientific Reports.

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Molecular analysis reveals that long-tailed macaques from Malaysian Borneo host a previously unidentified species of Plasmodium malaria parasite.

Researchers from The Hong Kong University of Science and Technology (HKUST) (HKUST) credited with important translational science and early discovery work Significant opportunity to replicate collaborative model to develop pipeline of extracellular tRNA synthetase therapeutics

A research team consisting of scientists from The Hong Kong University of Science and Technology (HKUST) (HKUST) and Beijing Tiantan Hospital have uncovered the mutational mechanism of how a rare and deadly brain cancer –secondary glioblastoma (sGBM) – progresses from its less lethal type.

A research team has discovered a new mechanism that could delay the degeneration of injured nerves, bringing new hope to the treatment of nerve damage and neurodegenerative diseases such as Parkinson and Amyotrophic Lateral Sclerosis (ALS).

An international team has developed an attachable guidewire that can move and steer towards a desired direction inside complicated blood vessels. The technology will contribute to increasing the success rate of heart disease treatment with a shorter cardiovascular disease surgery time and higher accuracy.

A key cell receptor that facilitates influenza A virus infection has been identified following decades of research.

Hepatocellular carcinoma diagnosis, prognosis and treatment could improve by identifying a closely associated protein.

Uncovered details of a molecular pathway in cancer cells could lead to improved treatment.

Turning off a bone receptor protein could potentially treat osteoporosis in children without affecting bone growth.

An engineered virus kills cancer cells more effectively than another virus currently used in treatments, according to Hokkaido University researchers.

A combined treatment may help tackle the rise of E. coli PI-7 in Saudi Arabia’s wastewater systems.

An international team of researchers has identified a novel route that regulates the signaling pathways induced by extracellular matrix (ECM). This may serve as a new diagnostic marker and therapeutic target in the fight against chronic liver diseases.

The mistletoe fig reduces toxic oxidative stress in diabetic rat brains, while also keeping the cortex wrinkly and improving cognition.

A nucleus-penetrating probe could lead to therapies for virus-related tumours.

A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has introduced a novel targeted drug delivery system in the fight against cancer.

HKBU scholars invented the world’s first multidimensional antimicrobial susceptibility testing system. The new technology can provide information about drug resistant pathogens present in patients, enabling doctors to accurately determine the effectiveness and appropriate dosage of antibiotics needed for effective treatment.