Diseases

News

09 Jan 2020
A small molecule could hold the key to tackling the protein build-up in nerve cells that occurs in several devastating neurological disorders.
child, autism, Malaysia
08 Jan 2020
Much-needed insight into raising young children with autism in Malaysia highlights the need to improve local research, awareness, acceptance and support services.
08 Jan 2020
New findings could lead the way towards treatments for intellectual disability in Down syndrome.
20 Dec 2019
Professor Ronald Ching Wan MA, Professor and Head of the Division of Endocrinology and Diabetes of the Department of Medicine and Therapeutics, and Professor Siew Chien NG, Professor of the Division of Gastroenterology and Hepatology of the Department of Medicine and Therapeutics and Associate Director of the Centre for Gut Microbiota Research under the Faculty of Medicine at The Chinese University of Hong Kong (CUHK), have received Croucher Senior Medical Research Fellowships 2020 in recognition of their excellent achievements in scientific research in medicine and the support that gives to the next generation of clinician scientists.
20 Dec 2019
Over 70% of rare disease patients and non-patients are aware of the patient registry but the participation rate accounted for less than 30%, according to a recent survey of the public’s acknowledgement of and participation in the rare disease patient registry.
20 Dec 2019
A recent study conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CUHK) revealed that Chinese women with polycystic ovary syndrome (PCOS) are at 4-fold higher risk of developing type 2 diabetes mellitus (T2DM) compared with those without the disorder, and also have younger onset of diabetes.
09 Dec 2019
Inaugural Nipah virus Conference convenes leading experts to strengthen global collaboration, improve efforts to combat deadly virus.
A research team, led by Prof June M. Kwak
06 Dec 2019
Scientists in Korea find a protein that mediates the interaction between the cellular systems involved in rapid responses against foreign genes in plants
Umetaro Suzuki a Japanese scientist best remembered for his research on beriberi
26 Nov 2019
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Salimuzzaman Siddiqui
22 Nov 2019
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
14 Nov 2019
Foremost society of kidney specialists highlights Singapore-led global study to better understand diabetes complications and reduce their prevalence.
30 Oct 2019
Development of novel agonist antibodies to treat cancer by collaboration between academia and industry
24 Oct 2019
Large-scale study to identify human adenovirus genotypes in Singapore leads to discovery of four new adenovirus strains and increase in strains linked to severe diseases. Researchers suggest use of antiviral therapies and adenovirus vaccines, and routine monitoring of adenovirus strains.
24 Oct 2019
A recent research led by a scientist at City University of Hong Kong (CityU) has discovered an easily transmitted DNA piece that can make a new type of hyper-resistant and deadly superbug become hyper-virulent quickly, posing an unprecedented threat to human health.
A single glucose-excited CN neuron extends bifurcated axonal branches
23 Oct 2019
When a fly eats sugar, a single brain cell sends simultaneous messages to stimulate one hormone and inhibit another to control glucose levels in the body. Further research into this control system with remarkable precision could shed light on the neural mechanisms of diabetes and obesity in humans.
23 Oct 2019
A research team from the School of Chinese Medicine at Hong Kong Baptist University (HKBU) has successfully developed a novel aptamer, i.e. a single-stranded piece of DNA, for the treatment of osteogenesis imperfecta (OI) with the aid of artificial intelligence (AI) technology. It is the first time a drug in Hong Kong has been granted orphan drug designation by the US Food and Drug Administration (FDA).
18 Oct 2019
A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.
17 Oct 2019
Faulty signalling pathway causes the heart to develop unnaturally while in the embryo stage, according to Duke-NUS Medical School researchers.
30 Sep 2019
X-rays could be tuned to deliver a more effective punch that destroys cancer cells and not harm the body.
20 Sep 2019
Researchers from Duke-NUS Medical School, in collaboration with the Agency for Science, Technology and Research’s Bioinformatics Institute, and the University of Texas Medical Branch, USA, have discovered that the dengue virus changes its shape through mutations in Envelope protein to evade vaccines and therapeutics. The study also gives insights on the types of treatment strategies to use at different stages of infection. This could give rise to new approaches in vaccine development and treatment for dengue disease.
17 Sep 2019
Differential changes in brain functional network connectivity in people with mild cognitive impairment may aid early tracking of Alzheimer’s disease and cerebrovascular disease.
12 Sep 2019
The formation of excess fibrous tissue in the heart, which underlies several heart diseases, could be prevented by inhibiting specific proteins that bind to RNA while its code is being translated.
DGIST Professor Jong Kyong Kim’s team in the Department of New Biology (right) and Researcher Eunmin Lee in the Department of New Biology (left)
29 Aug 2019
Successfully identified the existence of two types of 'gastric isthmus stem cells' with different roles and characteristics using a multi-color identification technology. Expects to clarify and treat causes of gastric diseases such as cancer.
27 Aug 2019
New study reveals enzyme plays key role in potentially fatal dengue haemorrhagic fever and shock; suggests clinically approved tryptase inhibitor could be key in future targeted treatment.
13 Aug 2019
UK Research and Innovation and its partners are funding 13 research programs, building collaborations across 10 countries, including Japan, China, Singapore and India.
02 Aug 2019
Scientists have succeeded in reducing levels of the bovine leukemia virus (BLV) in cows with severe infections by combining an immune checkpoint inhibitor and an enzyme inhibitor. The finding could be utilized to control other diseases in cattle, and perhaps in humans someday.
16 Jul 2019
New insight into a protein’s role in regulating tight DNA packing could have implications for combating tumor cell resistance to anti-cancer treatments.
15 Apr 2019
A delegation from Hong Kong Baptist University (HKBU) (HKBU) won a Gold Medal with the Congratulations of Jury, a Gold Medal and a Silver Medal at the 47th International Exhibition of Inventions of Geneva held in Switzerland from 10 to 14 April 2019.
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27 Mar 2019
A new model may help clinicians predict the possibility of death from severe dengue infection.
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21 Mar 2019
Researchers at Universiti Teknologi MARA reported in the journal Medicine a rare case of hepatocellular carcinoma cells migrating from the liver and settling in the jawbone and shoulder blade of a 61-year-old man.

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Giants in history

Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Iranian physician and bacteriologist Azar Andami (8 December 1926 – 19 August 1984) developed a cholera vaccine to combat an outbreak that swept through the Middle East, India, Southeast Asia, and Africa in 1937.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school. Lim, who helped found the National Zoo of Malaysia and re-establish the Malaysian Nature Society, had a particular interest in researching zoonotic diseases associated with small animals.
A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.