Diseases
News
29 May 2020
An international collaborative team from PROS Ehime University and CellFee Science, Japan; the Walter and Eliza Hall Institute, Australia; Pasteur Institute, France; and Foundation for Innovative New Diagnostics, Switzerland developed a new diagnostic blood test which detects recent exposure to ‘vivax’ malaria. The new test can also identify people who may harbor dormant liver-stage malaria parasites, which can cause illness. This new diagnostic approach has the potential to enhance malaria surveillance and accelerate elimination.
28 May 2020
A team of scientists and researchers from A*STAR’s Singapore Immunology Network and Jinan University, Guangzhou, have deciphered human embryonic immune cell development and discovered how the earliest macrophages in humans, a type of white blood cell of the immune system, stems from a distinct embryonic source and not the bone marrow.
28 May 2020
An adenovirus is now better able to target and kill cancer cells due to the addition of an RNA stabilizing element.
25 May 2020
Wastewater could be used as a surveillance tool to monitor the invasion, spread and eradication of COVID-19 in communities.
22 May 2020
Researchers have succeeded in detecting anti-avian influenza virus antibody in blood serum within 20 minutes, using a portable analyzer they have developed to conduct rapid on-site bio tests. If a suitable reagent is developed, this technology could be used to detect antibodies against SARS-CoV-2, the causative virus of COVID-19.
21 May 2020
A group of Hokkaido University researchers has developed a paper-based device that can easily and cheaply measure lithium ion concentration in blood, which could greatly help bipolar disorder patients.
20 May 2020
Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications.
16 May 2020
Thursday, 21 May 2020, 4:00 PM (GMT +8)
15 May 2020
As a first-in-the-world "rapid smart test kit", the cPass™ which can measure neutralising antibodies in an hour will be a huge boost to current COVID-19 investigations, from contact tracing, sero-prevalence survey, and assessment of herd immunity, longevity of protective immunity and efficacy of different vaccine candidates.
12 May 2020
Researchers from Daegu Gyeongbuk Institute of Science and Technology(DGIST) have developed an innovative method that allows them to visualize up to tens of different proteins simultaneously in the same cell. This technology could help scientists elucidate the complex protein interactions involved in degenerative diseases such as Alzheimer’s, deepening our understanding of their mechanisms and allowing for early detection and treatment.
28 Apr 2020
With the COVID-19 pandemic resulting in lockdowns in different parts of the world, from the US to many European nations, there have been intense debates on when and how we can safely reopen the economy.
New research led by Hong Kong Baptist University (HKBU) computer scientists has used a data-driven modelling approach to answer the time-critical question of when the stringent social distancing and quarantine measures against COVID-19 can be loosened so that normal life and economic activities can be restored in a safe manner.
16 Apr 2020
A small mitochondrial protein is necessary for energy production and its malfunction could be behind a range of degenerative diseases, according to study by Duke-NUS Medical School and their collaborators.
07 Apr 2020
New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease.
31 Mar 2020
Exercise and a cell-aging drug could help cases of chronic myopathy.
30 Mar 2020
Looking for experts to who can comment on the coronavirus pandemic? Our Focus On: Coronavirus resource connects journalists with experts prepared to speak with international media about different aspects of the pandemic, including public health, virology, economic impacts, travel and spread of information.
27 Mar 2020
A Communique from the InterAcademy Partnership urges countries to collaborate, use and share science-based information, and help the developing world.
18 Mar 2020
Scientists and clinicians from Duke-NUS Medical School, the Agency for Science, Technology and Research’s (A*STAR’s) Genome Institute of Singapore (GIS), and the Singapore General Hospital (SGH), have devised a novel drug combination that could treat a particularly deadly form of leukaemia, known as blast crisis (BC) chronic myeloid leukaemia (CML). The team has also developed strategies that may identify patients with early stage or chronic phase (CP) CML who are at increased risk of developing BC, and potentially preventing disease progression.
26 Feb 2020
The Hong Kong Polytechnic University (PolyU) has been collaborating with Queen Elizabeth Hospital (QE) and the Hospital Authority (HA) respectively to design and produce 3D-printed eye shields and face shields.
11 Feb 2020
New Delhi – To tackle the escalating problem of antimicrobial resistance, a new collaboration platform was launched in New Delhi, India, on 11 February. The platform, initiated by Stockholm International Water Institute (SIWI), will bring together actors from civil society, governments and the pharmaceutical industry. It could mean a major breakthrough for the responsible manufacturing of antibiotics and reduce the risk of the industry itself contributing to the spread of antimicrobial resistance.
06 Feb 2020
A global research collaboration, led by world class institutions in Singapore, the UK and the USA, has developed the most detailed catalogue of mutational fingerprints found in most types of cancers that could help clarify their developmental history and lead to new prevention and treatment strategies.
31 Jan 2020
Looking for experts to who can comment on the current coronavirus outbreak? With the novel coronavirus outbreak happening now, we have prepared an abbreviated Focus On to help connect journalists with experts who are prepared to speak with international media about different aspects, including public health, virology, travel, tourism, economic impacts and spread of information.
24 Jan 2020
Looking for experts to who can comment on the current coronavirus outbreak? With the new coronavirus outbreak happening now, we have prepared an abbreviated Focus On to help connect journalists with virus experts who are prepared to speak with international media as the situation unfolds.
24 Jan 2020
Testing for a gene expression pattern could reduce the number of colorectal cancer patients referred for unnecessary radical surgery.
23 Jan 2020
West Nile virus (WNV) inhibits autophagy — an essential system that digests or removes cellular constituents such as proteins — to induce the aggregation of proteins in infected cells, triggering cell death and brain inflammation (encephalitis), according to Hokkaido University researchers.
23 Jan 2020
Universiti Malaysia Sarawak haematologist Kuan Jew Win is looking for ways to detect certain blood diseases and cancers
early.
22 Jan 2020
A new compound could help doctors detect epileptic foci in the living human brain as well as further the understanding of psychiatric disease.
21 Jan 2020
Using tissue engineering techniques, researchers are developing living heart valves that can grow after implantation in the human heart.
20 Jan 2020
A resource for journalists to find stories and sources. Focus On: Brain highlights research and experts exploring questions ranging from basic structure and function, to technology, diseases and treatments.
20 Jan 2020
Blocking a central nervous system protein could treat irritable bowel syndrome.
14 Jan 2020
A team of researchers from the National University of Singapore has developed a personalised assessment tool which can detect the incidence of cancer, predict patient survivability and determine patient suitability for immunotherapy cancer treatment.
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Giants in history
Filipina paediatrician and scientist Perla Santos-Ocampo (25 July 1931 – 29 June 2012) made important contributions to treatments and policies that curbed debilitating and sometimes deadly diarrhoea-related diseases and malnutrition in children.
Singaporean physician Oon Chiew Seng (1916 – 31 March 2022) advanced dementia care and research in Singapore, and co-founded the Apex Harmony Lodge, the nation’s first nursing home for residents with dementia.
Vietnamese surgeon Tôn Thất Tùng (10 May 1912 – 7 May 1982) developed a pioneering technique that reduced the risks and mortality rate of liver operations.
Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Iranian physician and bacteriologist Azar Andami (8 December 1926 – 19 August 1984) developed a cholera vaccine to combat an outbreak that swept through the Middle East, India, Southeast Asia, and Africa in 1937.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school. Lim, who helped found the National Zoo of Malaysia and re-establish the Malaysian Nature Society, had a particular interest in researching zoonotic diseases associated with small animals.
A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Tu Youyou (born 30 December 1930) is a Chinese pharmaceutical scientist who was awarded the 2015 Nobel Prize in Physiology or Medicine for her work on extracting artemisin from sweet wormwood to treat malaria.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.