Diseases

News

23 Dec 2021
By searching for the protein transglutaminase 1 (TGM1) among patients with various autoimmune skin diseases, researchers have successfully identified a separate disease that can be linked to autoimmunity against TGM1. This backward method demonstrates a new way of identifying autoantigens as markers for various diseases. By letting autoantigens point to the disease, diagnosis and treatment can be facilitated, according to the study now published in PNAS.
15 Dec 2021
Zika virus infection hijacks glucose metabolism for its own good and to the detriment of infected foetuses.
08 Dec 2021
A new saliva-based COVID-19 Antigen Rapid Test (ART) technology co-developed by the SingHealth Duke-NUS Academic Medical Centre and the National University of Singapore shows promise in early clinical testing, outperforming existing ARTs and delivering results in minutes, with nearly comparable sensitivity to the gold standard Polymerase Chain Reaction (PCR) test.
The expression of the immune response gene ​​NLRC5 (red purple) is suppressed in SARS-CoV-2 (green) infected cells (Photo: Ji-Seung Yoo, Koichi Kobayashi).
07 Dec 2021
Scientists at Hokkaido University and Texas A&M University have identified a key mechanism used by the SARS-CoV-2 virus to evade host immune systems.
Immunofluorescence staining of uninfected and infected Vero E6 cells
30 Nov 2021
Researchers at the Department of Microbiology at The University of Hong Kong have succeeded in the isolation of SARS-CoV-2 Omicron variant from clinical specimens. This is the first known research team in Asia that has succeeded in isolating the Omicron variant. The isolated variant will enable the development and production of vaccines against Omicron, which has been designated as a "variant of concern" by the World Health Organization.
24 Nov 2021
Researchers from the Osaka City University Graduate School of Medicine have shown in patients with early-stage hepatocellular carcinoma who received cancer treatment that eliminating the hepatitis C virus with a direct-acting antiviral treatment reduces the risk of the liver cancer progression and increases overall patient survival.
16 Nov 2021
Scientists are turning to genomics to better understand the epidemiology of malaria and to inform control and elimination interventions and strategies. In the Lake Victoria region of Kenya, malaria burden remains very high despite more than a decade of intense control activities. A team of researchers from Osaka City University, Nagasaki University, London School of Hygiene and Tropical Medicine, and Mount Kenya University generated whole Plasmodium falciparum genome sequences from the lake region. Their analyses revealed that malaria parasites from this region appear distinct from other parasites from East Africa, while frequencies of known drug resistance markers were similar to those in other East African parasite populations. Their findings will help to develop improved surveillance tools to determine parasite transmission routes and aid clinical disease management.
A woman ahead of her time- Asima Chatterjee
15 Nov 2021
Giants in History: Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
08 Nov 2021
We have clarified at the molecular level the mechanism by which a microenvironment, a so-called niche that surrounds cancer cells, is formed in which stromal cells and immune cells are attracted at an initiation stage of breast cancer onset. A molecule called FRS2β is found to be critical for creating this microenvironment. The present finding is expected to be beneficial in prevention, diagnosis and treatment of cancers at the initiation stage.
Asia research News - Editor's Choice
05 Nov 2021
Quick seawater test may reveal health of corals, Infectious disease caused by a new nairovirus, Converting CO2 into useful compounds and Automated COVID-19 diagnosis from chest scans all in the November Editor's Choice. Plus our latest podcast: Gender and Conflict in Myanmar.
02 Nov 2021
The world’s largest analysis of gastric tumour cells provides a launch pad for scientists to plan more effective therapies.
19 Oct 2021
Researchers from Korea reveal the key protein involved in the development of aggressive prostate cancer
13 Oct 2021
Direct evidence that microtubules function as mechano-sensors and regulate the intracellular transport of molecules has been reported, leading to new possibilities in the fields of biomechanics, medicine, and biosensors.
05 Oct 2021
Researchers are empowering the elderly in Singapore to choose their preferred treatment option when diagnosed with end-stage kidney disease.
Transmission electron micrograph of the Yezo virus.
04 Oct 2021
A previously unknown virus that can infect humans and cause disease has been identified by scientists in Japan. The novel infectious virus, named Yezo virus and transmitted by tick bites, causes a disease characterized by fever and a reduction in blood platelets and leucocytes.
UNESCO and the L'Oréal Foundation International Prize for Women in Science 2022
01 Oct 2021
Paris, 29 September — UNESCO and the L'Oréal Foundation are unveiling the winners of this year’s International Prize for Women in Science, which honours five eminent women scientists with exceptional careers from the five regions of the world, as it has done annually since 1998.
Stop TB partnership
29 Sep 2021
Geneva, 28 September 2021 – The Stop TB Partnership today released new data showing how the COVID-19 pandemic and dismally low levels of funding represent the main barriers to achieving the United Nations Sustainable Development Goals of ending TB by 2030.
After intravenous injection into mice, STING-lipid nanoparticles (red) transported through blood vessels(green) accumulate in the liver (Takashi Nakamura, et al. Journal for ImmunoTherapy of Cancer. July 2, 2021).
17 Sep 2021
A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.
IMAGE
13 Sep 2021
iCeMS scientists and colleagues have designed a molecular code that powers up cancer-fighting immune cells.
Asia research News - Editor's Choice
10 Sep 2021
Magnetic patterns in meteorites, Treating mitochondrial diseases, underwater sensors and a broad COVID-19 vaccine in the September Editor's Choice. Plus, what's it like to communicate vaccine research in a pandemic and Asia Research News 2022.
07 Sep 2021
Recreating major pathological features of Parkinson’s disease in a lab-grown, human mini-brain will help researchers to explore new treatments. This is the first time that Lewy bodies, a hallmark of Parkinson’s disease in patients’ brains, have been produced in the laboratory, offering new insights into the disease.
06 Sep 2021
Using data from 1,107 patients dating back over 30 years, researchers have connected prognostic impact to poorly differentiated tumor size in hepatocellular carcinoma. Data confirmed previous findings that after resection, <2 cm sized tumors had excellent long-term outcomes. However, ≥2 cm and ≥5 cm sizes shared a risk of early recurrence with the latter size also at risk of early extrahepatic recurrence.
25 Aug 2021
A novel CT scan-based approach has revealed significant changes in a parameter indicating lung destruction in some asthmatics. This finding could lead to more personalized treatments for asthma accompanied by persistent airflow limitation.
20 Aug 2021
Sjögren's syndrome is an autoimmune disease that attacks the tear duct and salivary glands, leading to patients suffering unbearable dry eyes and mouth. To date, treatment options have been limited. But this may change thanks to a recently developed mouse model that will help explain the pathogenic mechanisms behind the disease.
10 Aug 2021
A new, energy-efficient method of electrical brain stimulation developed by researchers from the Daegu Gyeongbuk Institute of Science and Technology could aid stroke rehabilitation and has few side effects.
19 Jul 2021
A subset of fibroblasts located in small foci of tissue on the edges of extensive scarring produce a protein that protects against cell aging.
 IMAGE
14 Jul 2021
Researchers have found a way to enhance radiation therapy using novel iodine nanoparticles.
27 May 2021
Researchers at The International Islamic University Malaysia (IIUM) have developed an algorithmic approach to predict progression of a condition called pterygium, which involves abnormal tissue growth across the eye.
Plaque-eating microglia
21 May 2021
Single-cell gene studies are clarifying the roles of the brain’s specialised immune cell in Alzheimer’s disease and offer new avenues for treatment of this incurable condition.
19 May 2021
Scientists from Hokkaido University have shown that an antigen-based test for quantifying SARS-CoV-2 in saliva samples is simple, rapid, and more conducive for mass-screening.

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Researchers

Hong Kong Baptist University (HKBU)
Dr. Simon Quan-Bin Han is an Assistant Professor at the School of Chinese Medicine, Hong Kong Baptist University.
Kanazawa University
Dept of Medical Neuroscience, School of Medicine, Kanazawa University
Universiti Teknologi MARA (UiTM)
Kartini Ilias is a senior lecturer and clinical psychologist in Faculty of Health Sciences, Universiti Teknologi MARA, Puncak Alam, Selangor.
Korea Advanced Institute of Science and Technology (KAIST)
Professor in Electrical Engineering at Korea Advanced Institute of Science and Technology (KAIST).
Prof. Dr. Francisco J. Barrantes is the Head of the Laboratory of Molecular Neurobiology, BIOMED UCA-CONICET, Buenos Aires, Argentina.
The Chinese University of Hong Kong (CUHK)
Professor, School of Life Sciences, The Chinese University of Hong Kong
Aamir Jalal Al Mosawi is advisor in pediatrics and pediatric psychiatry at the Children Teaching Hospital of Baghdad Medical City.
Hokkaido University
Toru Kondo is Professor of the Division of Stem Cell Biology at the Institute for Genetic Medicine, Hokkaido University.
Professor and Head of Microbiology and Immunology Department, Faculty of Medicine, Lincoln University College (LUC) Malaysia.
Duke-NUS Medical School
Ashley St. John
Prof. Ashley St. John is an expert in viral immunology and emerging infectious diseases, such as dengue and Zika viruses. She heads the Laboratory of Immunity and Immune Pathology at Duke-NUS Medical School.
Professor in Agriculture and Education in the Iloilo Science and Technology University Leon Campus (ISAT U). Leon, ILOILO, PHILIPPINES