Diseases

News

25 Feb 2021
New study shows that uneven accumulation of amyloid β is linked to olfactory dysfunction or partial loss of smell, an early symptom of Alzheimer’s disease
24 Feb 2021
Springer Nature and the University of Tokyo to hold SDGs Symposium 2021, “Interdisciplinary science solutions for food, water, climate and ecosystems Sustainable Development Goals”
24 Feb 2021
A research team from the School of Life Sciences at The Chinese University of Hong Kong (CUHK) has recently discovered that SOX9 protein is an essential regulatory factor of choroid plexus function that ensures the correct composition of cerebrospinal fluid (CSF). The finding, recently published in the prestigious scientific journal Proceedings of the National Academy of Sciences of the United States of America (PNAS), has provided the scientific community a novel understanding to the molecular regulatory mechanisms behind the function of the blood-CSF barrier and lays the groundwork for developing novel therapeutic strategies for preventing and treating neurodevelopmental disorders.
24 Feb 2021
Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited. An international research team, including a biomedical scientist from City University of Hong Kong (CityU), has developed a high-throughput biological assay technique which enabled them to conduct a systematic analysis on the impact of nearly 100,000 genetic variants on the binding of transcription factors to DNA. Their findings provided valuable data for finding key biomarkers of type 2 diabetes for diagnostics and treatments. And they believe that the new technique can be applied to studies of variants associated with other genetic diseases.
Akihiko Sato, DVM, Ph.D.
18 Feb 2021
This article is an excerpt from the Hokkaido University research magazine “Tackling Global Issues vol.3 Fighting the menace of zoonosis" (link below).
Yoshihiro Sakoda, DVM, Ph.D.
12 Feb 2021
This article is an excerpt from the Hokkaido University research magazine “Tackling Global Issues vol.3 Fighting the menace of zoonosis" (link below).
10 Feb 2021
In a study published in Gastroenterology – Researchers at Osaka City University and The Institute for Medical Science, The University of Tokyo, in collaboration with Brigham and Women's Hospital in Boston, report the intestinal bacterial and viral metagenome information from the fecal samples of patients with recurrent Clostridioides difficile infection (rCDI). This comprehensive analysis reveals the bacteria and phages involved in pathogenesis in rCDI, and their remarkable pathways important for the recovery of intestinal flora function.
Hiroshi Kida, DVM, Ph.D
04 Feb 2021
This article is an excerpt from the Hokkaido University research magazine “Tackling Global Issues vol.3 Fighting the menace of zoonosis" (link below).
03 Feb 2021
Researchers from the School of Chinese Medicine (SCM) at Hong Kong Baptist University (HKBU) have developed a Chinese medicine formula named NeuroDefend that offers a potential novel treatment for Alzheimer’s disease (AD). Mouse model experiment results showed that the formula reduces the levels of amyloid-beta (Aβ) and insoluble hyperphosphorylated-tau protein, which are the major hallmarks of AD, in mice brains. It also improves cognitive function and memory in mice.
25 Jan 2021
The COVID-19 outbreak has brought unprecedented challenges to Hong Kong and, according to data from the Chinese Center for Disease Control and Prevention, the highest fatality rate has been in adults aged over 80. In view of this, Lingnan University in Hong Kong (LU) has launched a brand new programme to promote using Chinese medicine to prevent the transmission of COVID-19 in older adults, and reduce the infection risk in the spirit of “prevention is better than cure”.
19 Jan 2021
New ‘armoured’ T cells attack cancer without being suppressed by drugs given to transplant patients to avoid organ rejection.
28 Dec 2020
Investigations of a cellular protein have uncovered a possible link with schizophrenia.
iCeMS Ueda ABCB1
28 Dec 2020
iCeMS scientists have revealed how a transporter protein twists and squeezes compounds out of cells, including chemotherapy drugs from some cancer cells.
New IRAK4 mutations discovered
21 Dec 2020
Researchers baffled by an infant’s rare encephalitis case unusual in children found unheard-of mutations and a new way to examine the “immunity gene.”
20 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has been selected as the recipient of a large-scale Social Science Korea (SSK) project of the National Research Foundation of Korea.
When researchers inhibited Wnt signalling the anti-cancer drug ETC-159, they found that the reactivation of the hyperactive RAS-MAPK pathway led the cancer cells to undergo senescence, which is an ageing process that results in arrested growth.
20 Nov 2020
Cancer is a disease driven by mutations that alter the way biochemical signals control cell growth, division and migration. Scientists at Duke-NUS Medical School found out that, like Goldilocks, cancer is very picky about getting rapid growth just right.
19 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has succeeded in generating bipotential self-renewing iVPCs by direct lineage conversion.
19 Nov 2020
A research team, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) established an advanced direct conversion strategy to generate iMNs from human fibroblasts in large-scale with high purity, thereby providing a cell source for treatment of SCI.
13 Nov 2020
A Singapore study finds patients with chronic kidney disease need tailored nutrition guidance, as well as better communication with doctors and family support, to empower them to manage their condition.
11 Nov 2020
U.S. Food and Drug Administration (FDA) issued an emergency use authorization (EUA) for cPass™ SARS-CoV-2 Neutralization Antibody Detection Kit on 6th November 2020.
10 Nov 2020
MANILA, PHILIPPINES (10 November 2020) — The Asian Development Bank (ADB) has partnered with leading healthcare knowledge provider, the BMJ, to launch a new online coronavirus disease (COVID-19) Information Centre for healthcare professionals tackling the pandemic.
03 Nov 2020
Professor Hyug Moo Kwon, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has published a review paper at 'Nature Review Nephrology'.
03 Nov 2020
A group of students, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has created a map to help track the spread of the COVID-19 in Ulsan region.
02 Nov 2020
Innovators clinched 25 Gold Awards, 7 Best Innovation Awards, and 5 Foreign Special Awards at MTE2020 Special Edition : The COVID-19 International Innovation Awards
Lysosomes in a breast cancer cell.
29 Oct 2020
Scientists have revealed the molecular mechanism regulating the trafficking of lysosomes that increases the invasiveness of radioresistant cancer cells following radiotherapy.
28 Oct 2020
Hong Kong Baptist University (HKBU) scientists have invented a novel contrast agent for magnetic resonance imaging (MRI), which enables real-time visualisation and detection of the size and number of amyloid-beta in the brain, a main hallmark of Alzheimer’s disease (AD). The invention offers hope for early detection and large-scale routine screening of AD. It can also help to assess the efficacy of drugs used to treat it.
26 Oct 2020
Study confirms bats adopt multiple strategies to reduce pro-inflammatory responses, thus mitigating potential immune-mediated tissue damage and disease. Findings provide important insights for medical research on human diseases.
21 Oct 2020
Although most people are likely to accept a future vaccine against COVID-19 if one is proven safe and efficacious, the hesitancy of those who refuse vaccination could stall global efforts to achieve community immunity, suggests a study published in Nature Medicine.
20 Oct 2020
Osaka City University detects cancer cells in 2ml blood samples and connects them back to their origin tumor – creating a new diagnostic tool that may aid in quicker and more accurate anti-cancer measures.
14 Oct 2020
Osaka City University unravels the atomic architecture of the “Nap” protein complex found on Mycoplasma pneumoniae.

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Researchers

Professor and Head of Microbiology and Immunology Department, Faculty of Medicine, Lincoln University College (LUC) Malaysia.
Duke-NUS Medical School
Ashley St. John
Prof. Ashley St. John is an expert in viral immunology and emerging infectious diseases, such as dengue and Zika viruses. She heads the Laboratory of Immunity and Immune Pathology at Duke-NUS Medical School.
Professor in Agriculture and Education in the Iloilo Science and Technology University Leon Campus (ISAT U). Leon, ILOILO, PHILIPPINES