Diseases

News

30 Sep 2024
Duke-NUS Medical School
Scientists have discovered that blocking the activity of the hormone glucagon could treat a common and challenging type of heart failure that affects millions worldwide.
Campylobacter jejuni
25 Sep 2024
Osaka Metropolitan University
By targeting multiprotein molecule, antibody inhibits bacteria’s growth, pathogenicity
24 Sep 2024
Duke-NUS Medical School
• Two-year assessment provides critical insights and recommendations for strengthening genomic sequencing for infectious disease surveillance in 13 South and Southeast Asian countries. • Research helps to step up Asia’s preparedness across wide range of diseases.
COVID-19-associated pulmonary aspergillosis
20 Sep 2024
Osaka Metropolitan University
Incidence, risk factors found for pulmonary aspergillosis, an invasive fungal infection of lungs, among COVID-19 patients
How natural killer T cells shape the immune response to dengue virus
20 Sep 2024
Duke-NUS Medical School
A Duke-NUS Medical School-led study highlights the role of natural killer T cells in influencing the immune response to dengue virus, potentially reducing the severity of subsequent infections.
13 Sep 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a computer chip inspired by our brains, the potential link between asthma and diabetes, and how Japanese eels flee their predators after being swallowed.
IMAGE
13 Sep 2024
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
A better understanding of how cells regulate their membranes could lead to new treatments for diseases such as epilepsy and anemia.
For non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal for persons who might be overweight or obese.
12 Sep 2024
Osaka Metropolitan University
Whether immunotherapy or conventional chemotherapy carries less mortality risk depends on BMI
10 Sep 2024
Asia Research News
Seaweed helps brain health, Whales in long-distance relationships, Jumpstarting male fertility, Demystifying black hole turbulence, Shrimp to steel & Mpox Resources. Read all in the latest Editor's Choice.
A graphical representation illustrates what might be occurring in undamaged and damaged skin.
09 Sep 2024
Osaka Metropolitan University
Suppression of an enzyme might allow melanocytes to recover
Sterilization of cats and other companion animals, such as by removing the uterus, is a common procedure, with the donated uterus of cats providing the cells to generate feline induced pluripotent stem cells.
04 Sep 2024
Osaka Metropolitan University
Feeder-free induced pluripotent stem cells hold hope in therapies for cats’ chronic kidney disease
Digestive disorders and other life factors are found to contribute to chronic belching.
03 Sep 2024
Osaka Metropolitan University
Survey of 10,000 Japanese adults reveal leading causes of burp-related disorders
Compounds from nucleic acids derived from salmon milt DNA and torula yeast RNA showed effects against cancer cell growth.
29 Aug 2024
Osaka Metropolitan University
Specific nucleosides hinder replication of tumor cells in step toward cancer prevention
Compounds found in citrus and coconut could be the solution to oral disease in children and the elderly.
28 Aug 2024
Osaka Metropolitan University
A nonirritant, antibacterial solution to prevent oral inflammation may lie in citrus and coconut chemical compounds
Loss of Gα13 in ER+ breast cancer cells leads to increased cell growth and tumour development.
26 Aug 2024
Duke-NUS Medical School
The surprising discovery that cellular protein Gα13 may actually protect against—rather than promote growth of—the most commonly relapsing type of breast cancer signals potential for more effective and innovative treatments.
Mpox in Asia
23 Aug 2024
Asia Research News
Mpox has now been reported in Asia. Asia Research News has compiled a small selection of resources for better understanding.
Improvement effects of MOD06051. In the glomeruli of the disease group, neutrophils (green) that are positive for the NETs marker citrullinated histone H3 (Cit-H3; red) are observed. Cit-H3 was not observed in neutrophils infiltrating in the low-dose and high-dose treatment groups. (Yuka Nishibata, et al. Nature Communications. August 22, 2024)
22 Aug 2024
Hokkaido University
A newly developed compound that reduces harmful inflammation in rats caused by overactive neutrophils shows great potential as a safer treatment for various inflammatory diseases in humans.
20 Aug 2024
Tohoku University
A clinical trial conducted by Tohoku University researchers has lead to the approval of a treatment for patients with a rare, muscle-weakening disease called GNE myopathy.
20 Aug 2024
National Taiwan University
Pathogens hijack host cell functions by expressing or secreting effector proteins, creating environments conducive to their survival and reproduction. These pathogenic microorganisms—including eukaryotic parasites, prokaryotic bacteria, and viruses—express effector proteins that function as their "ammunition depot". These proteins are crucial for pathogen survival and dissemination, enhancing the efficiency of invasion, suppressing the host's immune system, or initiating pathogen replication. For instance, viruses may interfere with host signaling pathways, pushing cells into states that favor viral replication. Similarly, certain bacteria secrete toxins that disrupt the host cell cytoskeleton, facilitating pathogen invasion and spread. Additionally, pathogens can evade immune surveillance by suppressing the host's immune response, thereby increasing the likelihood of a successful infection.
16 Aug 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the ‘holy grail’ of insulin treatments, a new species that ate like a walrus, and keeping cool in smart, adaptive clothing.
05 Aug 2024
Ehime University
An experimental approach based on universal multi-branch general-purpose convolutional neural network
Ecklonia cava is a seaweed that may hold the key to Parkinson’s disease prevention. Credit: Osaka Metropolitan University
05 Aug 2024
Osaka Metropolitan University
Ecklonia cava, a brown algae seaweed, is shown to have the ability to protect against neurodegeneration
02 Aug 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are gene transplants that help flies live longer, a COVID-19 treatment using embryonic stem cells, and how a frog named after Darwin likes to get it on.
30 Jul 2024
Applied Microbiology International has announced that it has recruited 11 new Global Ambassadors from around the world.
The resistance mechanism of indisulam by YAP/TAZ activation
30 Jul 2024
Hiroshima University
The anti-tumor drug indisulam has shown promise both in cell cultures and in animal studies. However, clinical trials have shown fewer clear-cut results. Scientists from Hiroshima University Hospital have been researching the reasons behind this resistance to it.
26 Jul 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are the smallest and lightest drone that can pave the way for new models, how good intentions may have provoked a heatwave, and how eating fruit can stave off depression.
How venetoclax helps body fight leukemia
18 Jul 2024
Osaka Metropolitan University
Combination of venetoclax and azacitidine helps patients with AML who relapse after hematopoietic cell transplant
12 Jul 2024
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are how diversity in genetics and our microbiome influences our health, and how the shape of ice makes it slippery
Endolysin, a phage-derived antibacterial enzyme demonstrated specific activity against pathogenic Enterococcus bacteria.
10 Jul 2024
Osaka Metropolitan University
Researchers from Japan discover a new enzyme with promising antibacterial activity
Chronic allergic disorder eosinophilic esophagitis (EoE)
10 Jul 2024
Osaka Metropolitan University
First epidemiological study on incidence of EoE in Japan

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Giants in history

Tu Youyou (born 30 December 1930) is a Chinese pharmaceutical scientist who was awarded the 2015 Nobel Prize in Physiology or Medicine for her work on extracting artemisin from sweet wormwood to treat malaria.
Filipina paediatrician and scientist Perla Santos-Ocampo (25 July 1931 – 29 June 2012) made important contributions to treatments and policies that curbed debilitating and sometimes deadly diarrhoea-related diseases and malnutrition in children.
Singaporean physician Oon Chiew Seng (1916 – 31 March 2022) advanced dementia care and research in Singapore, and co-founded the Apex Harmony Lodge, the nation’s first nursing home for residents with dementia.
Vietnamese surgeon Tôn Thất Tùng (10 May 1912 – 7 May 1982) developed a pioneering technique that reduced the risks and mortality rate of liver operations.
Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Iranian physician and bacteriologist Azar Andami (8 December 1926 – 19 August 1984) developed a cholera vaccine to combat an outbreak that swept through the Middle East, India, Southeast Asia, and Africa in 1937.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school. Lim, who helped found the National Zoo of Malaysia and re-establish the Malaysian Nature Society, had a particular interest in researching zoonotic diseases associated with small animals.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes.