Diseases

News

Asia Research News Editors Choice
19 May 2023
Mushrooms 🍄get chattier after rainfall 🌧️, Two-organ chip answers fatty liver questions, History maps 🗺️vs future simulations, Restoring vision in blindness. Plus in our blog: Myanmar: Through eyes of leadership. Read all in the latest Editor's Choice.
12 May 2023
Specially coated surfaces help scientists investigate what happens when cell clusters are turned upside down.
11 May 2023
A protein that helps bats survive viral diseases might offer lessons for developing new anti-inflammatory treatments.
Damage to the liver induced by acetaminophen (dotted blue outlines) is almost completely mitigated by CoQ10-MITO-Porter (right), compared to the effect of phosphate buffered saline (left) and direct administration of CoQ10(center). (Mitsue Hibino, et al. Scientific Reports. May 10, 2023).
10 May 2023
A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.
The relationship between Japanese food and NAFLD
25 Apr 2023
A research group at the Osaka Metropolitan University analyzed the relationship between diet, muscle mass, and liver fibrosis progression in 136 patients with nonalcoholic fatty liver disease attending the Osaka Metropolitan University Hospital. The research group found that the group with the highest Japanese diet score had less advanced liver fibrosis, and that the intake of soy products, seafood, and seaweed was important.
14 Apr 2023
Research reveals a promising stem cell approach to correct photoreceptor cell degeneration, which underlies several forms of visual decline and blindness.
Chula Parkinson's gloves to reduce tremors
10 Apr 2023
Doctors at King Chulalongkorn Memorial Hospital have developed lightweight and easy-to-use Parkinson's gloves that can automatically reduce tremors, allowing patients to enjoy social life and reducing side effects from medication and risk from brain surgery.
Asia Research News monthly Editors Choice
10 Apr 2023
AI finds the first stars ✨were not alone, Auto-switch for large electronic devices, A metabolite against autoimmune diseases, & Converting fruit waste 🍊🍉into solar stills. Plus in our blog: A career worth doing, a life worth living. Read all in the latest Editor's Choice.
IMAGE
07 Apr 2023
A tiny platform empowers scientists to examine how gut and liver cells interact in health and disease.
Asia Research News - Editors Choice
18 Mar 2023
Scientists restore impaired kidney for the first time, How fibre composite fails when wet, Cleaner fish recognize themselves in pictures 🖼️🐟& The source of black carbon in the sea. Read all in the latest Editor's Choice. Plus our magazine Asia Research News 2023 is out now 🎉!
17 Mar 2023
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a fish that is both transparent and multicolored, making mice grow antlers, and surgery on a very small heart.
16 Mar 2023
PAXLOVID™ rollout continues with Laos, Malawi, Rwanda and Zambia as international access to oral treatments improves.
Covid-19 vaccines and syringe
07 Mar 2023
Researchers in Sarawak, Malaysia, measured the immunity responses of people who received different COVID-19 vaccines.
The RNP-ssODN is designed to ensure the CRISPR-Cas9 molecule is encapsulated by the LNP. Once inside the cells, the ssODN dissociates and CRISPR-Cas9 can carry out its effect. (Haruno Onuma, Yusuke Sato, Hideyoshi Harashima. Journal of Controlled Release. February 10, 2023).
02 Mar 2023
Lipid nanoparticles have been used to encapsulate CRISPR-Cas9 and deliver it to cells in mice, where it was highly effective at knocking down expression of a target protein.
Medical illustration of clindamycin-resistant group B Streptococcus bacteria.
17 Feb 2023
Antimicrobial resistance is a global public health threat. Asia Research News has prepared a resource for journalists to find stories and connect with scientists combating antimicrobial resistance.
16 Feb 2023
A new approach that ‘baits’ the caps or telomeres protecting the ends of chromosomes could provide information on how rapidly we are ageing and what we need to do to slow it down.
02 Feb 2023
Blocking an immune-regulating protein reverses the damage caused by acute and chronic kidney disease, a preclinical study suggests.
The fluorescent blinking of cyanine dye (Alexa Fluor 647, pink star) bound to RNA changes depending on the structure of the RNA. When the RNA is folded like a hairpin, the fluorescent blinking is fast, and when the RNA switches to a G-quadruplex, the blinking is slow (Akira Kitamura).
02 Feb 2023
A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.
Asia Research News: Editor's choice
20 Jan 2023
Overeating mechanism: why "eating just one chip"🍟 is impossible, Measuring hidden energy of gamma-ray bursts, Marine species that can adapt to ocean acidification & A rough start can lead to a strong bond, Read all in our first Editor's Choice of 2023. Plus our interview on what dengue vaccine approval in EU💉means for global dengue protection.
When the H5N1 HPAI virus (orange) affected a flock of crows in a public garden, it caused a mass die-off of crows. An Ezo red fox and a Japanese raccoon dog were also infected by the H5N1 HPAI virus, the former likely by consuming corpses of the crows, and the latter due to close contact with crow corpses (Illustration: Takahiro Hiono).
05 Jan 2023
Researchers at Hokkaido University have revealed the effects of high pathogenicity avian influenza virus infection on an Ezo red fox and a Japanese raccoon dog, linking their infection to a recorded die-off of crows.
04 Jan 2023
A research study led by scientists from the School of Chinese Medicine (SCM) at Hong Kong Baptist University (HKBU) has shown for the first time that the human gut bacterium Ruminococcus gnavus is a major trigger factor of diarrhoea-predominant irritable bowel syndrome (IBS-D). Based on this discovery, a new therapeutic target for the disease’s treatment was identified. The study also found that low-protein food items such as fresh fruits, vegetables and bread may help reduce the gut motility in IBS-D.
23 Dec 2022
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are how a wasp uses its genitals to defend itself, a compound commonly found in mushrooms that could delay cognitive decline, and sunshine as a cure for myopia.
15 Dec 2022
Understanding how bats tolerate viral infections, Material separates water from...water, The virtual sense of touch polished to next level and COVID-19 negatively impacted early-careers and female researchers. Read all in the December's Editor's Choice.
12 Dec 2022
Revelations about the mechanisms of two key proteins which maintain the asymmetric distribution of cholesterol within the cell membrane could help understand and treat diseases linked to its imbalance
09 Dec 2022
Silencing the gene, called WWP2, in patients in the early stages of cardiomyopathy could delay progression to heart failure by controlling immune cell infiltration and activation, and halting the formation of excessive scar tissue, preclinical data suggest.
09 Dec 2022
− The European Commission Approved QDENGA (TAK-003) for Use in Individuals Four Years of Age and Older [i] − QDENGA Becomes the Only Dengue Vaccine Approved in the EU for Use in Individuals Regardless of Previous Dengue Exposure [i]
Flossie Wong-Staal
08 Dec 2022
Giants in History: Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
07 Dec 2022
First-in-the-world high-resolution imaging allows scientists to study the dengue protein in greater detail to yield valuable insights.
24 Nov 2022
Understanding how bats tolerate viral infections without developing symptoms may lead to better ways of combatting human disease.
18 Nov 2022
Exploring virtual human-agent relationships, A fly protein gives clue for human cancers, Rare earth elements formed in neutron star mergers 💥, One-stop process for hydrogen production. Read all in the November's Editor's Choice plus Upcoming event K4DM KNOWLEDGE MARKETPLACE – Bangkok 2022: Exchanging Ideas for a Democratic Myanmar.

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Researchers

Aamir Jalal Al Mosawi is advisor in pediatrics and pediatric psychiatry at the Children Teaching Hospital of Baghdad Medical City.
Hokkaido University
Toru Kondo is Professor of the Division of Stem Cell Biology at the Institute for Genetic Medicine, Hokkaido University.
Professor and Head of Microbiology and Immunology Department, Faculty of Medicine, Lincoln University College (LUC) Malaysia.
Duke-NUS Medical School
Ashley St. John
Prof. Ashley St. John is an expert in viral immunology and emerging infectious diseases, such as dengue and Zika viruses. She heads the Laboratory of Immunity and Immune Pathology at Duke-NUS Medical School.
Professor in Agriculture and Education in the Iloilo Science and Technology University Leon Campus (ISAT U). Leon, ILOILO, PHILIPPINES

Giants in history

Singaporean physician Oon Chiew Seng (1916 – 31 March 2022) advanced dementia care and research in Singapore, and co-founded the Apex Harmony Lodge, the nation’s first nursing home for residents with dementia.
Vietnamese surgeon Tôn Thất Tùng (10 May 1912 – 7 May 1982) developed a pioneering technique that reduced the risks and mortality rate of liver operations.
Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Iranian physician and bacteriologist Azar Andami (8 December 1926 – 19 August 1984) developed a cholera vaccine to combat an outbreak that swept through the Middle East, India, Southeast Asia, and Africa in 1937.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school. Lim, who helped found the National Zoo of Malaysia and re-establish the Malaysian Nature Society, had a particular interest in researching zoonotic diseases associated with small animals.
A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.