Diseases

Skeletal muscle stem cells in hibernating Syrian hamsters preserve their ability to function by suppressing their activation during the hibernation period, a research team led by Hiroshima University has shown. This insight may lead to a broader understanding of the maintenance of muscle tissue under prolonged low temperature conditions and may eventually lead to therapeutic applications.

Lymphatic Drug Delivery System (LDDS) is an emerging type of cancer treatment, but its efficacy depends on how efficiently the drugs reach the lymphatic system. A research team from Tohoku University has clarified how the physical and chemical features of medicines affect how they move through the lymphatic and blood systems, helping to advance the clinical development of LDDS.

Smokers could be at higher risk of post-COVID symptoms

A simple tablet could change the way deadly breathing disorders are treated, with no need for electricity, machines, or gas tanks.

A fast and efficient tool could change the way researchers collect tiny therapeutic packages from cell cultures, offering a low-cost approach that avoids lengthy processing and complex procedures.

Innovative approaches in cancer screening, drug development, and radioactive hazard protection are accelerating healthcare solutions.

From icy seas to humid forests, research collaborations between the United Kingdom and Malaysia are helping to advance our understanding of diseases, develop vaccines and antibiotics, preserve precious habitats and address the challenge of plastic waste.

Duke-NUS and NUHS scientists uncover a complex web of genetic, age-related and microbial factors that increase the risk of stomach cancer.

A new study suggests that the gut may play a surprising role in childhood migraine. Researchers found that improving gut health could help reduce headache pain and frequency in some children.

Exercise restores a key cellular balance in ageing muscles, helping them stay stronger and more resilient.

An AI system that learns from experienced endoscopists and pathologists helps doctors in low-resource areas quickly check stomach health using standard endoscopy images.

National Taiwan University research team uses single-cell analysis to reveal how exhausted T cells drive immunotherapy resistance and identify a potential new therapeutic strategy.

Leveraging cutting-edge tools in genomics, medical imaging and data science, five research teams from Duke and Duke-NUS have been awarded joint Research Collaboration Pilot Project grants.

Brain atlas, From perfume to plastic, Stable solar power, Plant aging switch, Anti-cancer droplets, Greener gold, Extreme star factory and How research shapes sustainability policy. Read all in the latest Editor's Choice.

Scientists have developed a new computational tool that maps multi-gene pathways more comprehensively than ever before. The study uncovered a previously unknown protein pathway that, when blocked, kills blood cancer cells. The discovery could lead to new therapies for patients with drug-resistant blood cancers.

Elastic fiber component level in human hepatic stellate cells may predict liver damage

A research group led by Associate Professor Islam MD Parvez and Professor Kenji Hato of the Graduate School of Agriculture at Ehime University has developed "Hort-YOLO," a real-time monitoring system for horticultural crops. This system is an advanced object detection network focused on accurate and context-aware analysis of crops, and simultaneously achieves a balance between annotation speed and scalability of supervised learning, making it practical for deployment in real-world environments.

A new scoring system using common clinical parameters accurately identifies chronic liver disease patients with a significantly increased risk of developing liver cancer. This tool acts as a universal predictor, helping doctors guide surveillance recommendations for patients with diverse liver diseases, including metabolic dysfunction associated steatotic liver disease.

Researchers from National Taiwan University Hospital and collaborating institutions have demonstrated that finerenone, a new-generation nonsteroidal mineralocorticoid receptor antagonist (MRA), significantly reduces the risk of death and major heart and kidney events compared with spironolactone in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D).

Scientists from National Taiwan University and the National Institutes of Applied Research of Taiwan develop a rapid and accurate microfluidic device that generates precise drug gradients and outperforms manual dilution, enabling reliable multi-drug screening for high-throughput and personalized medicine.

A seven-year study of 470 patients revealed that a severe fungal lung infection once mainly seen in specific high-risk groups is increasingly affecting elderly patients and those with common cancers who are not receiving traditional high-risk treatments, suggesting current prevention strategies may be missing vulnerable populations.

Untangling cosmic knots, Samurai jellyfish, Controlling rogue antibodies, Search for anti-ulcer vaccine & Metal-recovering yeast. Plus next SciCom coffee talk on experiences in science journalism in the AI era and WHO guide to reporting on non communicable diseases. Read all in the latest Editor's Choice.

A novel study from scientists at National Taiwan University challenges the long-held view of ketone bodies as mere energy substrates, revealing instead that those produced during lactation act as epigenetic signals that promote beige adipocyte formation and protect against obesity.

Researchers at National Taiwan University have discovered how light, electricity, and tiny forces can work together to help wounds heal naturally and leave fewer scars, offering new hope for chronic wound care.

Duke-NUS scientists have built one of the largest and most comprehensive maps of the developing human brain, marking a major step forward in testing new therapies for Parkinson’s disease and other neurological conditions

The COVID-19 pandemic has provided researchers with a wealth of information on contemporary successes and failures in combating an emerging pathogen. This study outlines a total of 22 opportunities and strategies based on urban functionality and typology to help communities better prepare for and mitigate the effects of the next pandemic.

Female individuals may experience a three-fold reduction in mortality risk from coronary heart diseases, when following recommended exercise guidelines, compared to male individuals, according to a study published in Nature Cardiovascular Research.

A new report from the SingHealth Duke-NUS Global Health Institute (SDGHI), supported by the Octava Foundation, has mapped Singapore’s programmes supporting children’s mental health.

A new study suggests that the same henna pigments that change your skin or hair that distinctive orange-red color could be used for another purpose: treating liver disease.

SOSE researchers are looking at a possible vaccine for H. pylori, a widely common bacterium that causes stomach ulcers and raises the risk for stomach cancer.