15 Sep 2020
Compared to Minimally Invasive Surgery, Endoscopic Submucosal Dissection (ESD) represents an advanced less-invasive endoscopic treatment for early gastrointestinal cancer. ESD has significant advantages as an organ preservation surgical treatment, but it is technically challenging with substantial risk of perforation and bleeding. The Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has been collaborating with researchers from Singapore since 2010 to develop a flexible endoscopic robotic system. This novel system was specifically designed to enhance the safety and efficacy of ESD for the treatment of gastrointestinal cancer. Using the first prototype flexible endoscopic robot, our team at CU Medicine had successfully performed ESD for treatment of early gastric cancer in 2011. The flexible endoscopic robot is now further redesigned and developed for performing ESD in the colorectum– namely The EndoMaster EASE (Endoluminal Access Surgical Efficacy) System. CU Medicine led the world’s first clinical trial on robotic colorectal ESD using the EndoMaster EASE System which commenced in May this year and has demonstrated satisfactory outcomes thus far. Researchers believe this innovative technology will enhance advanced endoscopic resection and benefit more patients with early colorectal cancer who will require ESD treatment.
04 Sep 2020
Pregnant mice fed diets high in omega-6 fats and low in omega-3 fats are shown in a new study to produce offspring whose brains had a higher level of dopamine-producing neurons—the neurological reward system. These mice went on to chase hyper-caloric diets, suggesting that the fats in a pregnant mother's diet may control the eating habits of her children, and potentially offering a new obesity-prevention strategy.
03 Sep 2020
Conference will see leading regional thought leaders, policymakers, C-suite officers, senior and middle level hospital and healthcare, e-health, clinical operations, medical and nursing professionals convene to explore new ways to innovate and collaborate.
21 Aug 2020
Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer.
21 Aug 2020
Uterine fibroid is a common benign gynaecological disease for women of reproductive age and often leads to heavy menstrual bleeding, pelvic pain and pressure related symptoms. Both surgical and non-surgical treatment options, such as High-Intensity-Focused-Ultrasound (HIFU), are available for patients nowadays. The Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has developed a modified HIFU treatment protocol for patients with uterine fibroid. The innovative procedure implements a modified energy transmission protocol and oxytocin augmentation which has proved to provide better therapeutic outcomes than other non-surgical treatments. The findings were recently published in the international journal Ultrasound in Medicine & Biology.
18 Aug 2020
Under the “Saving the Lives of Healthcare Workers” project in the Philippines, ASSIST and Project HOPE will distribute kits of personal protective equipment (PPE) to select hospitals and health facilities in COVID-19 hotspots in the Philippines.
17 Aug 2020
Duke-NUS spinout, PairX, led by US and Singapore scientists and investors, to advance immunotherapy biotech exclusively licensed from Duke-NUS.
11 Aug 2020
Scientists from the Daegu Gyeongbuk Institute of Science and Technology, Republic of Korea, discover a new way to diagnose Alzheimer’s disease by analyzing the levels of specific proteins in nasal discharge. This simple and inexpensive method could help in timely diagnosis of Alzheimer’s disease, in order to start treatment as soon as possible, thus delaying disease progression.
11 Aug 2020
A large cohort study conducted by the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine), in collaboration with investigators from the University of Sydney, Australia, has discovered that shortened DNA telomere length is a useful biomarker linked to a higher risk of developing cardiovascular disease in patients with type 2 diabetes. The Endocrinology and Diabetes team of CU Medicine evaluated this biomarker in over 5,300 type 2 diabetes patients during a 13-year follow-up period. Patients with cardiovascular disease at baseline or during follow-up had shorter tail-ends of DNA strands, expressed as relative Leukocyte Telomere Length (rLTL), than those who never had cardiovascular disease. For each unit relative decrease in rLTL, the risk of cardiovascular disease increased by 25%. These results have been published in the leading diabetes journal, Diabetes Care.
30 Jul 2020
In a May 2020 Webinar, Dr. Sam Shah, Global Digital Health Advisor and Consultant with UK’s National Health System (NHS) discusses how the COVID-19 pandemic is reshaping healthcare with technology, specifically the response of UK’s NHS.
29 Jul 2020
COVID19 is teaching us one more new lesson – to look for new-onset diabetes and other non-communicable diseases in COVID19 patients by post-COVID19 vigilance.
01 Jul 2020
Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in poor prognosis of cancer patients.
17 Jun 2020
A new study found that animals sampled in the wildlife-trade supply chain bound for human consumption had high proportions of coronaviruses, and that the proportion of positives significantly increases as animals travel from traders, to large markets, to restaurants.
03 Jun 2020
Researchers from Hong Kong Baptist University (HKBU) have invented a nanostructure that can stimulate neural stem cells to differentiate into nerve cells. They found that the transplantation of these nerve cells into rats with Parkinson's disease progressively improved their symptoms, with the new cells replacing damaged nerve cells around the transplantation site. This novel invention provides promising insights into stem cell therapies and offers hope of a new treatment for Parkinson's disease.
29 May 2020
An international collaborative team from PROS Ehime University and CellFee Science, Japan; the Walter and Eliza Hall Institute, Australia; Pasteur Institute, France; and Foundation for Innovative New Diagnostics, Switzerland developed a new diagnostic blood test which detects recent exposure to ‘vivax’ malaria. The new test can also identify people who may harbor dormant liver-stage malaria parasites, which can cause illness. This new diagnostic approach has the potential to enhance malaria surveillance and accelerate elimination.
28 May 2020
A team of scientists and researchers from A*STAR’s Singapore Immunology Network and Jinan University, Guangzhou, have deciphered human embryonic immune cell development and discovered how the earliest macrophages in humans, a type of white blood cell of the immune system, stems from a distinct embryonic source and not the bone marrow.
28 May 2020
An adenovirus is now better able to target and kill cancer cells due to the addition of an RNA stabilizing element.
25 May 2020
Wastewater could be used as a surveillance tool to monitor the invasion, spread and eradication of COVID-19 in communities.
22 May 2020
Researchers have succeeded in detecting anti-avian influenza virus antibody in blood serum within 20 minutes, using a portable analyzer they have developed to conduct rapid on-site bio tests. If a suitable reagent is developed, this technology could be used to detect antibodies against SARS-CoV-2, the causative virus of COVID-19.
21 May 2020
A group of Hokkaido University researchers has developed a paper-based device that can easily and cheaply measure lithium ion concentration in blood, which could greatly help bipolar disorder patients.
20 May 2020
Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications.
16 May 2020
Thursday, 21 May 2020, 4:00 PM (GMT +8)
15 May 2020
As a first-in-the-world "rapid smart test kit", the cPass™ which can measure neutralising antibodies in an hour will be a huge boost to current COVID-19 investigations, from contact tracing, sero-prevalence survey, and assessment of herd immunity, longevity of protective immunity and efficacy of different vaccine candidates.
12 May 2020
Researchers from Daegu Gyeongbuk Institute of Science and Technology(DGIST) have developed an innovative method that allows them to visualize up to tens of different proteins simultaneously in the same cell. This technology could help scientists elucidate the complex protein interactions involved in degenerative diseases such as Alzheimer’s, deepening our understanding of their mechanisms and allowing for early detection and treatment.
28 Apr 2020
With the COVID-19 pandemic resulting in lockdowns in different parts of the world, from the US to many European nations, there have been intense debates on when and how we can safely reopen the economy. New research led by Hong Kong Baptist University (HKBU) computer scientists has used a data-driven modelling approach to answer the time-critical question of when the stringent social distancing and quarantine measures against COVID-19 can be loosened so that normal life and economic activities can be restored in a safe manner.
16 Apr 2020
A small mitochondrial protein is necessary for energy production and its malfunction could be behind a range of degenerative diseases, according to study by Duke-NUS Medical School and their collaborators.
07 Apr 2020
New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease.
31 Mar 2020
Exercise and a cell-aging drug could help cases of chronic myopathy.
30 Mar 2020
Looking for experts to who can comment on the coronavirus pandemic? Our Focus On: Coronavirus resource connects journalists with experts prepared to speak with international media about different aspects of the pandemic, including public health, virology, economic impacts, travel and spread of information.
27 Mar 2020
A Communique from the InterAcademy Partnership urges countries to collaborate, use and share science-based information, and help the developing world.
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Giants in history
Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Iranian physician and bacteriologist Azar Andami (8 December 1926 – 19 August 1984) developed a cholera vaccine to combat an outbreak that swept through the Middle East, India, Southeast Asia, and Africa in 1937.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school. Lim, who helped found the National Zoo of Malaysia and re-establish the Malaysian Nature Society, had a particular interest in researching zoonotic diseases associated with small animals.
A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.