Diseases

News

11 Aug 2023
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are particle pollution linked to antibiotic resistance and microplastics being found in the body, fossils that show a marine reptile that used filter feeding, and how a connection in our brains compares our rewards to ones that others received.
28 Jul 2023
Duke-NUS Medical School
Scientists have isolated potent neutralising antibodies from a COVID-19 vaccinated SARS survivor that exhibited remarkable breadth against known sarbecoviruses. The antibodies targeted a conserved region of the spike protein and blocked receptor binding and viral fusion. These findings could guide the development of broadly active therapeutics against current and future coronaviruses.
26 Jul 2023
The consortium’s multidisciplinary executive committee comprises of both local and international oral health researchers.
19 Jul 2023
Duke-NUS Medical School
Omega-3 lysolipids are important for protecting the liver from dietary fat, according to Duke-NUS researchers and collaborators from SGH.
18 Jul 2023
Research stories from the International Congress of Genetics in Melbourne Tuesday 18 July 2023
07 Jul 2023
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a way to avoid biopsies by catching free-floating DNA, a large dip in the Earth’s surface under the Indian Ocean, and how people who brush their teeth before bed seem to have healthier hearts.
16 Jun 2023
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a potential answer to the question of which came first the chicken or the egg, vaginal seeding to boost baby microbiomes, and looking at remnants of the universe that used to be filled with gas.
09 Jun 2023
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are ice-free Arctic summers, how monkey malaria gets transmitted, and over 300 new species discovered in the lower Mekong.
01 Jun 2023
Duke-NUS Medical School
Tests could soon identify patients who will respond well to the available treatment for chronic myeloid leukaemia and those who will be resistant to it—which could improve their chances of survival.
Asia Research News Editors Choice
19 May 2023
Asia Research News
Mushrooms 🍄get chattier after rainfall 🌧️, Two-organ chip answers fatty liver questions, History maps 🗺️vs future simulations, Restoring vision in blindness. Plus in our blog: Myanmar: Through eyes of leadership. Read all in the latest Editor's Choice.
12 May 2023
National Institute for Materials Science (NIMS)
Specially coated surfaces help scientists investigate what happens when cell clusters are turned upside down.
11 May 2023
Duke-NUS Medical School
A protein that helps bats survive viral diseases might offer lessons for developing new anti-inflammatory treatments.
Damage to the liver induced by acetaminophen (dotted blue outlines) is almost completely mitigated by CoQ10-MITO-Porter (right), compared to the effect of phosphate buffered saline (left) and direct administration of CoQ10(center). (Mitsue Hibino, et al. Scientific Reports. May 10, 2023).
10 May 2023
Hokkaido University
A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.
The relationship between Japanese food and NAFLD
26 Apr 2023
Osaka Metropolitan University
A research group at the Osaka Metropolitan University analyzed the relationship between diet, muscle mass, and liver fibrosis progression in 136 patients with nonalcoholic fatty liver disease attending the Osaka Metropolitan University Hospital. The research group found that the group with the highest Japanese diet score had less advanced liver fibrosis, and that the intake of soy products, seafood, and seaweed was important.
14 Apr 2023
Duke-NUS Medical School
Research reveals a promising stem cell approach to correct photoreceptor cell degeneration, which underlies several forms of visual decline and blindness.
Chula Parkinson's gloves to reduce tremors
10 Apr 2023
Doctors at King Chulalongkorn Memorial Hospital have developed lightweight and easy-to-use Parkinson's gloves that can automatically reduce tremors, allowing patients to enjoy social life and reducing side effects from medication and risk from brain surgery.
Asia Research News monthly Editors Choice
10 Apr 2023
Asia Research News
AI finds the first stars ✨were not alone, Auto-switch for large electronic devices, A metabolite against autoimmune diseases, & Converting fruit waste 🍊🍉into solar stills. Plus in our blog: A career worth doing, a life worth living. Read all in the latest Editor's Choice.
IMAGE
07 Apr 2023
Institute for Integrated Cell-Material Sciences (iCeMS) at Kyoto University
A tiny platform empowers scientists to examine how gut and liver cells interact in health and disease.
Asia Research News - Editors Choice
18 Mar 2023
Asia Research News
Scientists restore impaired kidney for the first time, How fibre composite fails when wet, Cleaner fish recognize themselves in pictures 🖼️🐟& The source of black carbon in the sea. Read all in the latest Editor's Choice. Plus our magazine Asia Research News 2023 is out now 🎉!
17 Mar 2023
Asia Research News
Asia Research News monitors the latest research news in Asia. Some highlights that caught our attention this week are a fish that is both transparent and multicolored, making mice grow antlers, and surgery on a very small heart.
16 Mar 2023
PAXLOVID™ rollout continues with Laos, Malawi, Rwanda and Zambia as international access to oral treatments improves.
Covid-19 vaccines and syringe
10 Mar 2023
Universiti Malaysia Sarawak
Researchers in Sarawak, Malaysia, measured the immunity responses of people who received different COVID-19 vaccines.
The RNP-ssODN is designed to ensure the CRISPR-Cas9 molecule is encapsulated by the LNP. Once inside the cells, the ssODN dissociates and CRISPR-Cas9 can carry out its effect. (Haruno Onuma, Yusuke Sato, Hideyoshi Harashima. Journal of Controlled Release. February 10, 2023).
02 Mar 2023
Hokkaido University
Lipid nanoparticles have been used to encapsulate CRISPR-Cas9 and deliver it to cells in mice, where it was highly effective at knocking down expression of a target protein.
Medical illustration of clindamycin-resistant group B Streptococcus bacteria.
17 Feb 2023
Asia Research News
Antimicrobial resistance is a global public health threat. Asia Research News has prepared a resource for journalists to find stories and connect with scientists combating antimicrobial resistance.
16 Feb 2023
Duke-NUS Medical School
A new approach that ‘baits’ the caps or telomeres protecting the ends of chromosomes could provide information on how rapidly we are ageing and what we need to do to slow it down.
02 Feb 2023
Duke-NUS Medical School
Blocking an immune-regulating protein reverses the damage caused by acute and chronic kidney disease, a preclinical study suggests.
The fluorescent blinking of cyanine dye (Alexa Fluor 647, pink star) bound to RNA changes depending on the structure of the RNA. When the RNA is folded like a hairpin, the fluorescent blinking is fast, and when the RNA switches to a G-quadruplex, the blinking is slow (Akira Kitamura).
02 Feb 2023
Hokkaido University
A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.
Asia Research News: Editor's choice
20 Jan 2023
Asia Research News
Overeating mechanism: why "eating just one chip"🍟 is impossible, Measuring hidden energy of gamma-ray bursts, Marine species that can adapt to ocean acidification & A rough start can lead to a strong bond, Read all in our first Editor's Choice of 2023. Plus our interview on what dengue vaccine approval in EU💉means for global dengue protection.
When the H5N1 HPAI virus (orange) affected a flock of crows in a public garden, it caused a mass die-off of crows. An Ezo red fox and a Japanese raccoon dog were also infected by the H5N1 HPAI virus, the former likely by consuming corpses of the crows, and the latter due to close contact with crow corpses (Illustration: Takahiro Hiono).
05 Jan 2023
Hokkaido University
Researchers at Hokkaido University have revealed the effects of high pathogenicity avian influenza virus infection on an Ezo red fox and a Japanese raccoon dog, linking their infection to a recorded die-off of crows.
04 Jan 2023
Hong Kong Baptist University (HKBU)
A research study led by scientists from the School of Chinese Medicine (SCM) at Hong Kong Baptist University (HKBU) has shown for the first time that the human gut bacterium Ruminococcus gnavus is a major trigger factor of diarrhoea-predominant irritable bowel syndrome (IBS-D). Based on this discovery, a new therapeutic target for the disease’s treatment was identified. The study also found that low-protein food items such as fresh fruits, vegetables and bread may help reduce the gut motility in IBS-D.

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Giants in history

Tu Youyou (born 30 December 1930) is a Chinese pharmaceutical scientist who was awarded the 2015 Nobel Prize in Physiology or Medicine for her work on extracting artemisin from sweet wormwood to treat malaria.
Filipina paediatrician and scientist Perla Santos-Ocampo (25 July 1931 – 29 June 2012) made important contributions to treatments and policies that curbed debilitating and sometimes deadly diarrhoea-related diseases and malnutrition in children.
Singaporean physician Oon Chiew Seng (1916 – 31 March 2022) advanced dementia care and research in Singapore, and co-founded the Apex Harmony Lodge, the nation’s first nursing home for residents with dementia.
Vietnamese surgeon Tôn Thất Tùng (10 May 1912 – 7 May 1982) developed a pioneering technique that reduced the risks and mortality rate of liver operations.
Ruby Sakae Hirose (1904 – 1960) was a Japanese-American scientist whose research contributed significantly to our understanding of blood clotting, allergies and cancer.
Iranian physician and bacteriologist Azar Andami (8 December 1926 – 19 August 1984) developed a cholera vaccine to combat an outbreak that swept through the Middle East, India, Southeast Asia, and Africa in 1937.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Salimuzzaman Siddiqui (19 October 1897 – 14 April 1994) was an artist and chemist from Pakistan whose research focused on natural products from plants.
Umetaro Suzuki (7 April 1874 – 20 September 1943) was a Japanese scientist best remembered for his research on beriberi, a disease caused by vitamin B1 deficiency, characterized by limb stiffness, paralysis and pain.
Barry Paw (29 August 1962 – 28 December 2017) was a biologist and oncologist who discovered several novel genes and their functions in red blood cells.
Indian organic chemist Asima Chatterjee (1917 to 2006) studied the medicinal properties of plant products, especially compounds known as vinca alkaloids.
Filipino chemist and pharmacist Manuel A. Zamora (29 March 1870 – 9 July 1929) is best remembered for his discovery of the tiki-tiki formula to combat beriberi, a disease caused by Vitamin B1 deficiency.
Indian scientist and physician Upendranath Brahmachari (19 December 1873–6 February 1946) is best known for creating a drug called Urea Stibamine, used to safely and reliably treat visceral leishmaniasis (or Kala-azar), a severe infection caused by the Leishmania parasite.
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school. Lim, who helped found the National Zoo of Malaysia and re-establish the Malaysian Nature Society, had a particular interest in researching zoonotic diseases associated with small animals.
Japanese chemist Takamine Jokichi (3 November 1854 – 22 July 1922) founded the Tokyo Artificial Fertilizer Company, where he isolated a starch-digesting enzyme (named takadiastase) from the fungus Aspergillus oryzae.
A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes.