Biology Microbiology
News
18 Mar 2023
Scientists restore impaired kidney for the first time, How fibre composite fails when wet, Cleaner fish recognize themselves in pictures đŒïžđ& The source of black carbon in the sea. Read all in the latest Editor's Choice. Plus our magazine Asia Research News 2023 is out now đ!
21 Feb 2023
Sifting through sewage for SARS-CoV-2 genetic material could help authorities tailor infection control policies.
02 Feb 2023
Blocking an immune-regulating protein reverses the damage caused by acute and chronic kidney disease, a preclinical study suggests.
30 Nov 2022
Osaka Metropolitan University researchers introduced seven proteins, thought to let bacteria swim by switching the direction that their helical bodies spiral, into a strain of synthetic bacterium with minimal genetic information. As a result, they confirmed that the synthetic bacterium named syn3, which is normally spherical, formed a helix that could swim by spiraling. Further investigation revealed that only two of these newly added proteins were required to make syn3 capable of minimal swimming. This swimming synthetic bacterium can be said to be the smallest mobile lifeform genetically, as it contains the fewest number of genes.
10 Oct 2022
The SARS-CoV-2 Omicron variant escapes the immune response better than its coronavirus ancestors, but has also facilitated our transition to a society that can live with COVID-19.
15 Sep 2022
Cellular structures called mitochondria depend on microproteins to assist and control the assembly of a protein chain that extracts energy from nutrients, according to a new study by scientists in Singapore.
26 Aug 2022
Osaka Metropolitan University researchers have clarified that an adenosine analogâthe antibiotic toyocamycinâis taken up into cells by a concentrative nucleoside transporter (CNT) in Candida albicans, an opportunistic yeast fungus that causes candidiasis infections. This was also true of the human CNT3 protein. They found that C. albicans CNT and human CNT3 proteins take up similar molecules at different rates depending on their molecular size and structure. These results are expected to lead to the development of new antifungal drugs that are effective only against C. albicans and safe for humans.
05 Jul 2022
Innate immunity is activated when the pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs). We show that a liver-derived secretory protein LECT2, a hepatokine, binds to the HGF receptor MET, a proto-oncogene product, to suppress the proliferation signal of MET. LECT2 activates retinoic acid-inducible gene-I, enhancing antiviral and innate immune responses through MET. Thus, LECT2 is an anti-proliferative and immunoregulatory factor that could be a therapeutic target for viral infections and cancer.
14 Apr 2022
Bacteria hitchhike on red blood cells, New model simulates effects of exercise on muscles, Argon found in air of ancient atmosphere and Revealing emergent elastic fields of chiral crystals. Read all in the April Editor's Choice and this month's Asia Research News 2022 magazine pick - Asia's race to outsmart antimicrobial resistance.
29 Mar 2022
Mycobacteria are a group of pathogenic bacteria that cause diseases like leprosy and tuberculosis in humans. Now, a new study by scientists at Hiroshima University finds that mycobacteria are associated with red blood cells at lung infection sites, an interaction that has escaped scientific notice for 140 years since the discovery of the organism causing tuberculosis.
08 Mar 2022
Scientists develop a method to genetically label neurons with a single gene of interest in mice by combining the anterograde transsynaptic spread of adeno-associated virus serotype 1 (AAV1) with intersectional gene expression. In two distinct circuits: the retina/primary visual cortex to the superior colliculus and the bilateral motor cortex to the dorsal striatum, injections of AAV1 expressing either Cre or Flpo recombinases and the Cre/Flpo double-dependent AAV into two upstream regions and the downstream region, respectively, were used to label postsynaptic neurons receiving inputs from the two upstream regions.
22 Feb 2022
A Japanese research team created a new way to sort living cells suspended in fluid using an all-in-one operation in a lab-on-chip that required only 30 minutes for the entire separation process.
31 Jan 2022
Garden soil houses a variety of bacteria and their natural byproducts â including one that may help halt tumor growth. Lankacidins are molecules that can be isolated from Strepomyces rochei, a common bacterium in soil. In addition to antimicrobial properties, a type of lankacidins, called lankacidin C, can inhibit tumor activity in various cancer cell lines, including leukemia, melanoma, ovarian and breast cancers. Lankacidin C offers a potential foundation on which to design anticancer drugs, but its structure is complicated and difficult to manipulate, according to an international research group. The same group recently identified where antitumor activity is housed on the molecule and has now used that information to simplify lankacidin as a potential starting point to engineer treatments.
27 Sep 2021
The missing link isnât a not-yet-discovered fossil, after all. Itâs a tiny, self-replicating globule called a coacervate droplet, developed by two researchers in Japan to represent the evolution of chemistry into biology.
20 Jul 2021
Using electron microscopy and high-speed atomic force microscopy, researchers show the internal molecular motor behind the gliding mechanism for Mycoplasma mobile to consist of two ATP synthase-like molecules. Sharing a similar structure with ATP synthase suggests a common evolutionary ancestor. This synthase-like ATPase is challenging the origin of cells and proteins themselves.
08 Jul 2021
Researchers at The University of Tokyo Institute of Industrial Science use artificial intelligence to predict the size of cells over time without the need for simplifying assumptions, which may lead to a new understanding of microbiology principles and improved drug manufacturing from recombinant bacteria
17 Jun 2021
Researchers from Hiroshima University now have a better understanding of the mechanism underlying how certain bacteria can transfer genetic material across taxonomic kingdoms, including to fungi and protists. Their work, published in Frontiers in Microbiology, could have applications in changing how bacteria perform certain functions or react to changes in their environment.
24 May 2021
In collaboration with Kanazawa University, researchers from Osaka City University used high-speed atomic force microscopy (HS-AFM) to visualize at the nanometer level the movement of individual particles within the parasitic bacterium Mycoplasma mobile. After confirming the outline on the surface of the cell structure in an immobilized state with previous data gathered from electron microscopy, the team succeeded in visualizing the real-time movements of the internal structure by scanning the outside of the cell with HS-AFM.
11 May 2021
âBy looking at substances in volcanos, lakes and hotsprings, you can start to see the ecosystems that existed billions of years ago,â says Mayuko Nakagawa, a microbiologist and specially-appointed assistant professor at the Earth-Life Science Institute (ELSI) based at the Tokyo Institute of Technology, Japan. She analyses components left by microorganisms with colleagues from various disciplines, while as a lab manager, she looks after cutting-edge equipment and visitors from different countries.
11 May 2021
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02 Apr 2021
Scientists in Japan have developed and tested a novel probiotic formulation to control severe diarrhea in calves, ensuring their health and reducing mortality, and in turn reducing economic loss.
10 Feb 2021
In a study published in Gastroenterology â Researchers at Osaka City University and The Institute for Medical Science, The University of Tokyo, in collaboration with Brigham and Women's Hospital in Boston, report the intestinal bacterial and viral metagenome information from the fecal samples of patients with recurrent Clostridioides difficile infection (rCDI). This comprehensive analysis reveals the bacteria and phages involved in pathogenesis in rCDI, and their remarkable pathways important for the recovery of intestinal flora function.
04 Feb 2021
Cells replicate their genetic material and divide into two identical clones to perpetuate life. Some cells pause in the process with a single, undivided nucleus. When the cell resumes division after such a pause, the nucleus can become caught in the fissure, splitting violently, and killing both cells. But that is not always the case. Researchers from Hiroshima University in Japan are starting to understand how active nuclear displacement rescues cell death.
16 Aug 2020
Researchers in Kanazawa University has recently reported their study in Nano Letters regarding a high-speed atomic force microscopy study on a biological event that happens during flu virus enters infects its host cell. The real-time visualization of influenza A hemagglutinin (HA) has enhanced the understanding of fusogenic transition of HA and its interactions with host endosomes.
10 Jul 2020
Scientists demonstrate that the information about host bacteriaâbacteriophage (phage) associations derived from worldâs first metagenome analysis is useful for the development of phage therapies against intestinal pathobionts.
07 Apr 2020
Researchers at Kanazawa University and Tsukuba University report in Nanoscale that the physical properties of extracellular bacterial membrane vesicles are significantly diverse. The properties for a single type of bacterium as well as for different types are found to be highly heterogeneous.
03 Sep 2019
DGIST Professor Sanghoon Leeâs team developed a novel neuromodulation interface that converts friction energy into for electrical neurostimulation energy to treat underactive bladder. Expected to be widely applied for the treatment of neurological disorders.
13 Mar 2019
Indigenous bacteria show promise for cleaning up pollution.
06 Mar 2018
Understanding how bacteria help convert glacier bedrock into soil could help address desertification.
21 Feb 2018
A team of scientists, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST), has unveiled that the bacterium Chromobacterium piscinae produces cyanide, an inhibitory molecule, to defend themselves in the battle against Bdellovibrio bacteriovorus HD100.
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Researchers
Dr. Crumlish has researched aquatic microbial diseases, specifically ones that have economic impact in global aquaculture, and potential solutions to such infectious diseases. Her current project seeks to develop vaccines against antimicrobial resistance in aquaculture.
Dr. Tay has researched antibodies and diseases like malaria and SARS-CoV-2 at A*STAR. His focus is on discovering methods for developing antibodies that can be used in therapies against multidrug-resistant pathogens.
Dr. Ikhsan is an associate professor at the Department of Aquaculture, University Putra Malaysia. She specializes in the field of Aquatic Microbial Ecology particularly in the development of innovative and sustainable microbial management strategies through understanding of the host-microbe interaction for enhanced microbial stability.
Dr. Bifani is a principal investigator at A*STAR ID Labs at their Antimicrobial Resistance Lab. He has extensively researched antimicrobial resistance in tuberculosis and malaria. He is also an associate professor and research director at the Yong Yoo Lin School of Medicine, National University of Singapore.
Dr. Deng is a biomedical scientist with a special interest in bacterial virulence, including gene regulation, signaling pathways, and RNA epigenetics. He has worked on virulence regulation in pathogens to discover new therapies against bacterial infections.
Dr. Mitchell is a professor at the Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST). His primary research interest is the study of bacterial strains that attack and prey on other bacteria, including antimicrobial-resistant pathogens.
Dr. Soojin Jang heads the Antibacterial Resistance Research Laboratory at Institut Pasteur Korea, where her team focuses on discovering new antibacterial agents for âsuperbugsâ or bacteria resistant to most antibiotics.
Department of Microbiology / Biomolecular Sciences
Universiti Teknologi MARA
Malaysia
Myungin Baek is currently an Assistant Professor at Daegu Gyeongbuk Institute of Science and Technology (DGIST).
Assistant Professor of Environmental Science
Krishna Institute of Allied Sciences
Krishna Institute of Medical Sciences
Deemed To Be University, Karad
Aparna B. Gunjal is a microbiologist at Dr. D.Y. Patil, Arts, Commerce & Science College, India.
Professor Ahmed Al-Haddad, M.Sc., Ph.D. (Germany) is currently Professor of Microbiology and Medical Microbiology at College of Medicine and Health Sciences, Hadhramout University-Yemen.
He is the Founding-Dean of the first Faculty of Nursing in Yemen. He has over fifteen years of research and teaching experience in various domains of life sciences.
Al-Haddad has published many peer reviewed articles and conference papers in the areas of molecular biology, microbiology and antibiotics in National and International journals.
He is reviewer in different national and international Scientific Journals such as Annals of Clinical Microbiology and Antimicrobials, Journal of Microbiology and Antimicrobials, Sultan Qaboos University Medical Journal, British Biotechnology Journal.
He is a member of various national and international scientific organizations.
Currently Associate Professor at Universiti Putra Malaysia. Holds a PhD from University College of Wales and BSc (Hons) Genetics from the University of Liverpool
Professor and Head of Microbiology and Immunology Department,
Faculty of Medicine, Lincoln University College (LUC) Malaysia.
Giants in history
Minoru Shirota (April 23, 1899 â March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
Roseli Ocampo-Friedmann (23 November 1937 â 4 September 2005) was a Filipino-American scientist whose research focused on cyanobacteria and microorganisms that inhabit extreme environments.