Biology Microbiology

News

10 Oct 2022
The SARS-CoV-2 Omicron variant escapes the immune response better than its coronavirus ancestors, but has also facilitated our transition to a society that can live with COVID-19.
15 Sep 2022
Cellular structures called mitochondria depend on microproteins to assist and control the assembly of a protein chain that extracts energy from nutrients, according to a new study by scientists in Singapore.
26 Aug 2022
Osaka Metropolitan University researchers have clarified that an adenosine analog—the antibiotic toyocamycin—is taken up into cells by a concentrative nucleoside transporter (CNT) in Candida albicans, an opportunistic yeast fungus that causes candidiasis infections. This was also true of the human CNT3 protein. They found that C. albicans CNT and human CNT3 proteins take up similar molecules at different rates depending on their molecular size and structure. These results are expected to lead to the development of new antifungal drugs that are effective only against C. albicans and safe for humans.
05 Jul 2022
Innate immunity is activated when the pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs). We show that a liver-derived secretory protein LECT2, a hepatokine, binds to the HGF receptor MET, a proto-oncogene product, to suppress the proliferation signal of MET. LECT2 activates retinoic acid-inducible gene-I, enhancing antiviral and innate immune responses through MET. Thus, LECT2 is an anti-proliferative and immunoregulatory factor that could be a therapeutic target for viral infections and cancer.
Asia Research News Editor's Choice
14 Apr 2022
Bacteria hitchhike on red blood cells, New model simulates effects of exercise on muscles, Argon found in air of ancient atmosphere and Revealing emergent elastic fields of chiral crystals. Read all in the April Editor's Choice and this month's Asia Research News 2022 magazine pick - Asia's race to outsmart antimicrobial resistance.
Mycobacterial extracellular infection of red blood cells
29 Mar 2022
Mycobacteria are a group of pathogenic bacteria that cause diseases like leprosy and tuberculosis in humans. Now, a new study by scientists at Hiroshima University finds that mycobacteria are associated with red blood cells at lung infection sites, an interaction that has escaped scientific notice for 140 years since the discovery of the organism causing tuberculosis.
08 Mar 2022
Scientists develop a method to genetically label neurons with a single gene of interest in mice by combining the anterograde transsynaptic spread of adeno-associated virus serotype 1 (AAV1) with intersectional gene expression. In two distinct circuits: the retina/primary visual cortex to the superior colliculus and the bilateral motor cortex to the dorsal striatum, injections of AAV1 expressing either Cre or Flpo recombinases and the Cre/Flpo double-dependent AAV into two upstream regions and the downstream region, respectively, were used to label postsynaptic neurons receiving inputs from the two upstream regions.
Newly developed microfluidic chip
22 Feb 2022
A Japanese research team created a new way to sort living cells suspended in fluid using an all-in-one operation in a lab-on-chip that required only 30 minutes for the entire separation process.
Chemoenzymatic synthesis and physico-chemical and biological functions of monocyclic polyketide compound, lankacyclinone C
31 Jan 2022
Garden soil houses a variety of bacteria and their natural byproducts — including one that may help halt tumor growth. Lankacidins are molecules that can be isolated from Strepomyces rochei, a common bacterium in soil. In addition to antimicrobial properties, a type of lankacidins, called lankacidin C, can inhibit tumor activity in various cancer cell lines, including leukemia, melanoma, ovarian and breast cancers. Lankacidin C offers a potential foundation on which to design anticancer drugs, but its structure is complicated and difficult to manipulate, according to an international research group. The same group recently identified where antitumor activity is housed on the molecule and has now used that information to simplify lankacidin as a potential starting point to engineer treatments.
Answering a century-old question on the origins of life
27 Sep 2021
The missing link isn’t a not-yet-discovered fossil, after all. It’s a tiny, self-replicating globule called a coacervate droplet, developed by two researchers in Japan to represent the evolution of chemistry into biology.
20 Jul 2021
Using electron microscopy and high-speed atomic force microscopy, researchers show the internal molecular motor behind the gliding mechanism for Mycoplasma mobile to consist of two ATP synthase-like molecules. Sharing a similar structure with ATP synthase suggests a common evolutionary ancestor. This synthase-like ATPase is challenging the origin of cells and proteins themselves.
08 Jul 2021
Researchers at The University of Tokyo Institute of Industrial Science use artificial intelligence to predict the size of cells over time without the need for simplifying assumptions, which may lead to a new understanding of microbiology principles and improved drug manufacturing from recombinant bacteria
Broad transfer range of IncP1-type plasmid and its applications
17 Jun 2021
Researchers from Hiroshima University now have a better understanding of the mechanism underlying how certain bacteria can transfer genetic material across taxonomic kingdoms, including to fungi and protists. Their work, published in Frontiers in Microbiology, could have applications in changing how bacteria perform certain functions or react to changes in their environment.
24 May 2021
In collaboration with Kanazawa University, researchers from Osaka City University used high-speed atomic force microscopy (HS-AFM) to visualize at the nanometer level the movement of individual particles within the parasitic bacterium Mycoplasma mobile. After confirming the outline on the surface of the cell structure in an immobilized state with previous data gathered from electron microscopy, the team succeeded in visualizing the real-time movements of the internal structure by scanning the outside of the cell with HS-AFM.
Mayuko Nakagawa operating a stable isotope mass analyser
11 May 2021
“By looking at substances in volcanos, lakes and hotsprings, you can start to see the ecosystems that existed billions of years ago,” says Mayuko Nakagawa, a microbiologist and specially-appointed assistant professor at the Earth-Life Science Institute (ELSI) based at the Tokyo Institute of Technology, Japan. She analyses components left by microorganisms with colleagues from various disciplines, while as a lab manager, she looks after cutting-edge equipment and visitors from different countries.
Nakagawa in lab
11 May 2021
火山や湖、温泉の物質からは数十億年前に存在した微生物の生態系が見えてくると語るのは、東京工業大学・地球生命研究所(ELSI)の中川麻悠子特任助教。異分野の研究者たちと共に微生物の作り出した成分を解析する傍ら、ラボマネージャーとして国内外の訪問者サポートや最先端の機材の管理などを行っている。
One of the calves used in the clinical studies of FMR efficacy
02 Apr 2021
Scientists in Japan have developed and tested a novel probiotic formulation to control severe diarrhea in calves, ensuring their health and reducing mortality, and in turn reducing economic loss.
10 Feb 2021
In a study published in Gastroenterology – Researchers at Osaka City University and The Institute for Medical Science, The University of Tokyo, in collaboration with Brigham and Women's Hospital in Boston, report the intestinal bacterial and viral metagenome information from the fecal samples of patients with recurrent Clostridioides difficile infection (rCDI). This comprehensive analysis reveals the bacteria and phages involved in pathogenesis in rCDI, and their remarkable pathways important for the recovery of intestinal flora function.
Actin-dependent nuclear displacement observed in several mitotic mutants in fission yeast.
04 Feb 2021
Cells replicate their genetic material and divide into two identical clones to perpetuate life. Some cells pause in the process with a single, undivided nucleus. When the cell resumes division after such a pause, the nucleus can become caught in the fissure, splitting violently, and killing both cells. But that is not always the case. Researchers from Hiroshima University in Japan are starting to understand how active nuclear displacement rescues cell death.
16 Aug 2020
Researchers in Kanazawa University has recently reported their study in Nano Letters regarding a high-speed atomic force microscopy study on a biological event that happens during flu virus enters infects its host cell. The real-time visualization of influenza A hemagglutinin (HA) has enhanced the understanding of fusogenic transition of HA and its interactions with host endosomes.
10 Jul 2020
Scientists demonstrate that the information about host bacteria–bacteriophage (phage) associations derived from world’s first metagenome analysis is useful for the development of phage therapies against intestinal pathobionts.
07 Apr 2020
Researchers at Kanazawa University and Tsukuba University report in Nanoscale that the physical properties of extracellular bacterial membrane vesicles are significantly diverse. The properties for a single type of bacterium as well as for different types are found to be highly heterogeneous.
Dr. Sanghoon Lee in the Department of Robotics Engineering at DGIST (first to left) and research team
03 Sep 2019
DGIST Professor Sanghoon Lee’s team developed a novel neuromodulation interface that converts friction energy into for electrical neurostimulation energy to treat underactive bladder. Expected to be widely applied for the treatment of neurological disorders.
Image Name
13 Mar 2019
Indigenous bacteria show promise for cleaning up pollution.
Soil team samples
06 Mar 2018
Understanding how bacteria help convert glacier bedrock into soil could help address desertification.
Wonsik Mun
21 Feb 2018
A team of scientists, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST), has unveiled that the bacterium Chromobacterium piscinae produces cyanide, an inhibitory molecule, to defend themselves in the battle against Bdellovibrio bacteriovorus HD100.
Prof. Hirt
05 Feb 2018
Genetic analyses of a desert bacterium show it could help to improve crop production in arid lands.
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01 Feb 2018
Skin squames are a source of food for the bacteria found in air-cooling units, which produce odours even in a dust-free air-conditioning system, a research by Hong Kong Baptist University scholars revealed.
08 Dec 2017
Researchers at The Hong Kong Polytechnic University have recently found that bacteria that carry the colistin resistance gene mcr-1 commonly exist in human and various types of food and environmental samples collected from Hong Kong and the Chinese mainland.

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Researchers

Department of Microbiology / Biomolecular Sciences Universiti Teknologi MARA Malaysia
Myungin Baek is currently an Assistant Professor at Daegu Gyeongbuk Institute of Science and Technology (DGIST).
Assistant Professor of Environmental Science Krishna Institute of Allied Sciences Krishna Institute of Medical Sciences Deemed To Be University, Karad
Aparna B. Gunjal is a microbiologist at Dr. D.Y. Patil, Arts, Commerce & Science College, India.
Professor Ahmed Al-Haddad, M.Sc., Ph.D. (Germany) is currently Professor of Microbiology and Medical Microbiology at College of Medicine and Health Sciences, Hadhramout University-Yemen. He is the Founding-Dean of the first Faculty of Nursing in Yemen. He has over fifteen years of research and teaching experience in various domains of life sciences. Al-Haddad has published many peer reviewed articles and conference papers in the areas of molecular biology, microbiology and antibiotics in National and International journals. He is reviewer in different national and international Scientific Journals such as Annals of Clinical Microbiology and Antimicrobials, Journal of Microbiology and Antimicrobials, Sultan Qaboos University Medical Journal, British Biotechnology Journal. He is a member of various national and international scientific organizations.
Currently Associate Professor at Universiti Putra Malaysia. Holds a PhD from University College of Wales and BSc (Hons) Genetics from the University of Liverpool
Professor and Head of Microbiology and Immunology Department, Faculty of Medicine, Lincoln University College (LUC) Malaysia.

Giants in history

Minoru Shirota (April 23, 1899 – March 10, 1982) was a Japanese microbiologist who invented the popular fermented drink Yakult.
Roseli Ocampo-Friedmann (23 November 1937 – 4 September 2005) was a Filipino-American scientist whose research focused on cyanobacteria and microorganisms that inhabit extreme environments.