Biology
News
08 Oct 2024
An unprecedented rapid increase in anthropogenic fingerprints around 1952 in the global strata reflects the point in time when humanity began to overwhelm the Earth system
07 Oct 2024
Fluorescein angiography capable of assessing neural blood flow in chronic nerve compression neuropathy
07 Oct 2024
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.
07 Oct 2024
Mirror, mirror, in my tank, who’s the biggest fish of all? Sigma bond spotted, Balancing cell membrane, Exploring quantum squeezing and Outbreak preparedness. Read all in the latest Editor's Choice.
04 Oct 2024
A team of scientists in Singapore and the US uncovered how a protein that controls our biological clock modifies its own function, offering new ways for treating jet lag and seasonal adjustments
04 Oct 2024
Successful selection of compounds inhibiting the function of a transcription factor
04 Oct 2024
How multiple DNA binding proteins compete for the DNA substrate leads to different biochemical outcomes. Using single-molecule experiments, this work demonstrates that the regulatory protein Mei5-Sae3 complex stabilizes Dmc1 recombinases on RPA-coated DNA, leading to efficient RPA displacement and Dmc1 assembly, which in turn stimulates recombination progression.
01 Oct 2024
A gene that limits cellular damage could be the key to surviving prolonged cold exposure.
25 Sep 2024
The Androgen Receptor in Mesenchymal Progenitor Cells Drives Skeletal Muscle Mass Regulation
24 Sep 2024
By targeting multiprotein molecule, antibody inhibits bacteria’s growth, pathogenicity
20 Sep 2024
A Duke-NUS Medical School-led study highlights the role of natural killer T cells in influencing the immune response to dengue virus, potentially reducing the severity of subsequent infections.
20 Sep 2024
A research group has developed a new COVID-19 testing system using Janus particles—microparticles with two sides possessing distinctive molecular properties. These particles are engineered to bind specifically to target antigens, such as viral proteins, creating a low-cost, accurate, and rapid means of testing for viral diseases. The system’s versatility means it can potentially be used to test for other diseases and biomarkers linked to other conditions.
18 Sep 2024
Light-induced immunoassay coated with novel coronavirus spike proteins found highly sensitive even with weak light like a laser pointer
13 Sep 2024
Researchers from Osaka University found that T cells recognize neoself-antigens––abnormal, unfolded host proteins presented by major histocompatibility complex II (MHC-II) lacking the invariant chain––as non-self antigens, leading to the development of autoimmunity. Reactivation of Epstein–Barr virus, a known risk factor for lupus onset and exacerbation, increases the presentation of neoself-antigens by MHC-II, which could help explain the link between viral infection and autoimmune disease.
13 Sep 2024
A better understanding of how cells regulate their membranes could lead to new treatments for diseases such as epilepsy and anemia.
11 Sep 2024
Cleaner wrasse check their body size before fights due to having their own mental representation
10 Sep 2024
Mutant microalgae produce wax esters for biofuel feedstock with improved cold flow
09 Sep 2024
Seaweed helps brain health, Whales in long-distance relationships, Jumpstarting male fertility, Demystifying black hole turbulence, Shrimp to steel & Mpox Resources. Read all in the latest Editor's Choice.
05 Sep 2024
Medaka fish that lacked functional Hmgn2 genes were unable to distinguish between simple shapes, revealing a new function for the regulatory gene.
04 Sep 2024
Suppression of an enzyme might allow melanocytes to recover
03 Sep 2024
Studied oxidative stress and Parkinson’s disease as a case study
03 Sep 2024
Feeder-free induced pluripotent stem cells hold hope in therapies for cats’ chronic kidney disease
01 Sep 2024
- DGIST Professor Seo Byeong-Chan’s research team is the first in the world to discover how PAC channels work.
- Their research has revealed a method to prevent cell edema and tissue damage, which may help treat cancer and brain diseases.
27 Aug 2024
14-3-3η: A protein that helps fight RNA viruses but can also be manipulated by them. New research reveals its complex role in the immune response
26 Aug 2024
Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, used high-speed atomic force microscopy to observe dynamic changes in AMPA receptors, which are vital for brain communication. Their findings, published in ACS Nano, reveal how these receptors adapt during signal transmission and suggest potential targets for neurological therapies.
26 Aug 2024
A nonirritant, antibacterial solution to prevent oral inflammation may lie in citrus and coconut chemical compounds
26 Aug 2024
Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin.
23 Aug 2024
Professor Hsiao-Wei Yuan from the School of Forestry and Resource Conservation at National Taiwan University (NTU) has been leading a team since 2003 dedicated to the research and protection of the endangered Chinese Crested Tern, also known as the 'Mythical Bird,' with only fewer than 100 individuals remaining. Their efforts have drawn international attention to this species, leading to conservation efforts and showcasing Taiwan's efforts in biodiversity conservation and key research achievements. After 20 years of conservation efforts, the population of Chinese Crested Terns has increased to approximately 150 individuals.
22 Aug 2024
A newly developed compound that reduces harmful inflammation in rats caused by overactive neutrophils shows great potential as a safer treatment for various inflammatory diseases in humans.
Events
24 Jul 2024 to 28 Jul 2024
Asia’s largest bioindustry-focused gathering, BIO Asia–Taiwan 2024,
will be held July 24th to 28th, 2024, in Taipei, Taiwan.
26 Jul 2023 to 30 Jul 2023
BIO Asia–Taiwan is Asia's largest biotech networking event, and is jointly organized by the global Biotechnology Innovation Organization (BIO) and the Taiwan Bio Industry Organization (Taiwan BIO).
07 Nov 2022 to 09 Nov 2022
FCS2022 is jointly organized by eight major research institutes in Singapore and includes a line-up of internationally renowned cancer experts. The conference converges the latest cancer discoveries around the world and promises ground-breaking and innovative insights into cancer research.
30 Jul 2021
The International Union of Biochemistry and Molecular Biology (IUBMB), the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) and the College of Biochemists of Sri Lanka (CBSL), will conduct the 1st Virtual Education Symposium themed “The ‘New Normal’ Biochemistry and Molecular Biology Education”, on the 30thof July 2021.
01 Jun 2021 to 30 Jun 2021
The Ocean Celebration event runs 1-30 June 2021 and is organized by the Borneo Marine Research Institute of Universiti Malaysia Sabah.
19 Mar 2020 to 20 Mar 2020
Institute for the Advanced Study of Human Biology(ASHBi) holds the annual symposium with twenty-one speakers who are leading human biology including human development, genetics, and evolution.
14 Jan 2020 to 17 Jan 2020
Organised by the National Research Foundation (NRF) Singapore, the Global Young Scientists Summit (GYSS) brings together distinguished scientists, post-graduates and academics for four days of learning and mentoring from 14 to 17 January 2020.
28 Aug 2019
The 2019 Genome Expo is scheduled to be held at UNIST from August 28 to 29, 2019.
Researchers
Prof Jun Suzuki is a biochemist and the deputy director at the Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Japan.
Dr Sarkar is a senior research fellow at the Murdoch Children's Research Institute in Melbourne, Australia. She is
actively engaged in collaborating with academic and industry stakeholders and leads multiple projects for the development of novel therapeutics/vaccines to tackle antimicrobial resistance.
Sarfraz Ahmed is working as a Scientist at Harvard Medical School's Mass General Hospital. His research interests include Diseases and Therapeutics especially focus on Cancer and Therapeutics, Cancer Immunology, Photomedicine, Photo compounds and Photodevices for Cancer, Cancer and Natural agents, Nanomedicine and Nanotechnology for Cancer, Drugs resistance, Microbiology (Bacteriology & Virology) and Drugs resistance
Dr Fabien Grasset is a Research Director at the Centre national de la recherche scientifique (CNRS) and currently serving as Director of Research for Rennes Institute of Chemical Sciences (ISCR). His areas of expertise include materials chemistry, solid-state chemistry, nanotechnology, nanoparticles, optical coatings and thin films.
Dr. Eisuke Hasegawa is an Associate Professor at the Graduate School of Agriculture, Hokkaido University, where he heads the Animal Ecology Laboratory. His research interests include animal ecology; evolutionary biology; natural selection; sociality; and ethology.
Dr. Yukio Yasui is an Associate Professor at Kagawa University. He has dedicated his research work to ecology, ethology and evolutionary biology studies, with his more recent work on the evolution of sex.
Dr. Wong Sin Yeng is an associate professor and Deputy Director at the Institute of Biodiversity and Environmental Conservation, Universiti Malaysia Sarawak (UNIMAS), whose work has led to identifying hundreds of new plant species in Southeast Asia.
Dr Ashfaq Ahmad Shah 'اشفاک ' born on 6 June 1992, from south Kashmir, Doderkoot ددیرکوٹ Kulgam, Jammu and Kashmir, India is the infection immunity doctoral researcher at the Graphic Era (Deemed to be University), Dehradun, UK, India. Dr Shah is pursuing novel dimensions of infection immunity pertaining to the correlation and impact of phyto-immune components termed phytoalexins and phytoanticipins on the benign immune system of human beings. This parameter of immunology is termed phytoalexin-immunomodulation scrutiny. His area of interest lies in Preclinical and clinical studies, i.e. vaccine adjuvant development, development of anti-inflammatory and antimicrobial compounds, evaluation of antibiotic resistance, study of Immuno-modulatory activities, disease model studies, protease isolation against specific protein antigens, and the discipline of Kalology including tyrosinase inhibition, PPO inhibition, skin whitening agents, kerato-peeling etc. Dr Ashfaq is a Doctoral Researcher, Reviewer and Editorial member of several journals and books. He is having several publications in journals of national and international repute. So far he has published more than thirty scopus infection/immunology/pharmacology scientific papers, including Fifteen international book chapters and two international books. Mr Shah received the Young scientist award in August 2023 for his groundbreaking academic performance in the field of infection immunity. Mr Shah has also been an editor of Wikipedia pages in medical science since 2015 with more than 1000 edits in medical topics available to medical literature worldwide.
Dr. Zong-Hong Lin is a Professor at the Institute of Biomedical Engineering, National Tsing Hua University and at the Department of Biomedical Engineering, National Taiwan University.
Dr. Cheng-Siang Tan is an Associate Professor at the Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak (UNIMAS). He is an expert in infectious and emerging diseases and biosafety and biorisk management.
Dr. Crumlish has researched aquatic microbial diseases, specifically ones that have economic impact in global aquaculture, and potential solutions to such infectious diseases. Her current project seeks to develop vaccines against antimicrobial resistance in aquaculture.
Dr. Tay has researched antibodies and diseases like malaria and SARS-CoV-2 at A*STAR. His focus is on discovering methods for developing antibodies that can be used in therapies against multidrug-resistant pathogens.
Nguyen Huu Nghia is the Director of the Center for Environment and Disease Monitoring in Aquaculture (CEDMA) at the Research Institute for Aquaculture No.1 (RIA1) under Vietnam’s Ministry of Agriculture and Rural Development. He has co-managed various research efforts in Vietnam aquaculture as well as published recent research into the use of nanobubbles.
Dr. Ikhsan is an associate professor at the Department of Aquaculture, University Putra Malaysia. She specializes in the field of Aquatic Microbial Ecology particularly in the development of innovative and sustainable microbial management strategies through understanding of the host-microbe interaction for enhanced microbial stability.
Dr. Oehlers leads the Bacterial Pathogenesis Laboratory at A*STAR ID Labs, where he and his colleagues focus on identifying molecular bases of mycobacterial disease and, thus, deploy therapies that address antibiotic resistance in mycobacterial infections.
Dr. Yue Wang is senior principal investigator at the Antifungal Resistance Laboratory of A*STAR ID Labs, where his body of work focuses on virulence mechanisms of the fungal human pathogen Candida albicans.
Dr. Singhal serves as senior principal investigator at the Bacterial Immunopathology Lab at A*STAR ID Labs in Singapore. His work at A*STAR ID Labs revolves around three main pathogens: Mycobacterium tuberculosis, Gram-negative bacteria and Dengue virus.
Dr. Bifani is a principal investigator at A*STAR ID Labs at their Antimicrobial Resistance Lab. He has extensively researched antimicrobial resistance in tuberculosis and malaria. He is also an associate professor and research director at the Yong Yoo Lin School of Medicine, National University of Singapore.
Dr. Yan is an assistant professor at the Department of Biomedical Sciences, City University of Hong Kong (CityU). His current research focuses on developing genomic tools to dissect lncRNA function and mechanism in diseases and to identify genetic variations that contribute to disease pathogenesis.
Dr. Deng is a biomedical scientist with a special interest in bacterial virulence, including gene regulation, signaling pathways, and RNA epigenetics. He has worked on virulence regulation in pathogens to discover new therapies against bacterial infections.
Dr. So Iwata is a Professor at the Graduate School of Medicine Kyoto University and the Group Director of the SACLA Science Research Group, RIKEN SPring-8 Center. He has investigated how specialized membrane channels remove antimicrobial drugs from inside bacterial cells.
Dr. Mitchell is a professor at the Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST). His primary research interest is the study of bacterial strains that attack and prey on other bacteria, including antimicrobial-resistant pathogens.
Dr. Soojin Jang heads the Antibacterial Resistance Research Laboratory at Institut Pasteur Korea, where her team focuses on discovering new antibacterial agents for “superbugs” or bacteria resistant to most antibiotics.
Assistant Professor Izumi Fukunaga grew up in Japan and Malaysia and went to London to study neuroscience. Her research focuses on how sensory circuits in the brain function.
Professor Gail Tripp is a neurobiologist who established the OIST Children’s Research Center to undertake research on the nature, etiology and management of ADHD with English and Japanese speaking children and families.
Assistant Professsor Lauren Sallan is a fish paleobiologist who uses big data — the fossil record — to study how some species win and others lose. Her multiple TED Talks on the evolution of fishes, mass extinction and paleontology have received over 3 million views.
Dr Owen Rackham is an expert in the development of computational approaches for cell reprogramming and disease-gene association.
Dr. Sonia Chotani is a computational biologist working in the area of small open reading frames and RNA translation in human diseases.
Dr. Dong currently works at the Asian Institute of Technology. He does research in Aquaculture, Pathology, Infectious Diseases, and Aquatic Bioscience.
Giants in history
Chinese biochemist Chi Che Wang (1894 - 1979), one of the first Chinese women to study abroad, advanced to prominent research positions at American institutions including the University of Chicago and the Northwestern University Medical School.
Pakistani botanist Azra Quraishi (22 September 1945 – 22 November 2002) is recognised for developing virus-free seed potatoes that increased potato production in Pakistan by an estimated five per cent.
Flora Zaibun Majid ( 1939–2018) was an accomplished Bangladeshi researcher in botany and nutrition science and the first female chairperson of the Bangladesh Council of Scientific and Industrial Research.
Sálim Moizuddin Abdul Ali (12 November 1896 – 20 June 1987), commonly referred to as the Birdman of India, was the first person to conduct systematic surveys of birds from across India.
Indian botanist Shipra Guha-Mukherjee (13 July 1938 – 15 September 2007) made a breakthrough discovery that enabled the genetic study of plants and, by extension, the development of improved varieties of rice, wheat, potatoes, and other crops.
During her short life, Fahire Battalgil (1902 - 1948) achieved renown as the first zoologist from Turkey to make strides in the field of freshwater fish biodiversity.
Michiaki Takahashi (17 February 1928 – 16 December 2013) was a Japanese virologist who developed the first chickenpox vaccine.
Irene Ayako Uchida’s (8 April 1917 – 30 July 2013) strides to understand genetic diseases such as Down syndrome paved the way for early screening of chromosomal abnormalities in foetuses.
Baron Kitasato Shibasaburo (29 January 1856 – 13 June 1931) was a Japanese physician and bacteriologist whose work led to a new understanding of preventing and treating tetanus, diphtheria and anthrax.
By isolating soil microorganisms and studying the compounds they produce, Satoshi Omura (born 1935) discovered almost 500 organic compounds with unique properties that were produced by these microorganisms, including many new antibiotics.
Chinese-American virologist and molecular biologist Flossie Wong-Staal (27 August 1946 – 8 July 2020) was the first scientist to clone HIV and determine the function of its genes.
Maharani Chakravorty (1937 – 2015) was one of India’s earliest molecular biologists whose research paved the way for advances in the treatment of bacterial and viral infections.
Archana Sharma (16 February 1932 - 14 January 2008) conducted research into plant and human genetics that expanded the understanding of both botany and human health. In relation to botany, she uncovered the means by which asexually-reproducing plants evolve into new species.
Hwang Hye-seong (5 July 1920 – 14 December 2006) was an expert on Korean royal court cuisine, the knowledge of which she dedicated her career to keeping alive. Formerly an assistant professor of nutritional science, Hwang met the last kitchen court lady in the Joseon Dynasty Han Hui-sun and, from her, learned about the culinary traditions of the royal court.
In 1915, pathologist Katsusaburo Yamagiwa and his research assistant Koichi Ichikawa became the first to prove that chronic exposure to chemicals can cause cancer.
Reiji Okazaki (8 October 1930 – 1 August 1975) and Tsuneko (7 June 1933) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Tsuneko (7 June 1933) and Reiji Okazaki (8 October 1930 – 1 August 1975) were a Japanese couple who discovered Okazaki fragments – short sequences of DNA that are synthesized during DNA replication and linked together to form a continuous strand.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Husband and wife team, Kimishige (3 December 1925 – 6 July 2018) and Teruko Ishizaka (28 September 1926 – 4 June 2019) discovered the antibody class Immunoglobulin E (IgE) that triggers allergic reactions. They also discovered that IgE antibodies attach to white blood cells, known as mast cells, releasing histamine, which causes allergic reactions.
Lim Boo Liat (21 August 1926 – 11 July 2020), a leading authority in the conservation of Malaysia’s biological diversity, had his initial interest in the outdoors piqued by nature lessons in school. Lim, who helped found the National Zoo of Malaysia and re-establish the Malaysian Nature Society, had a particular interest in researching zoonotic diseases associated with small animals.
A pioneer of bio-organic chemistry, Darshan Ranganathan (4 June 1941 – 4 June 2001) is remembered for developing a protocol for synthesising imidazole, a compound used to make antifungal drugs and antibiotics. Widely considered India’s most prolific researcher in chemistry, she also published dozens of papers in renowned journals on protein folding, molecular design, chemical simulation of key biological processes, and the synthesis of functional hybrid peptides and nanotubes.
In his over 30 year career in rice research, Munshi Siddique Ahmad (1924 – 19 October 2011) developed more than 30 varieties of high-yielding rice, including the BRRI Shail strain, which was responsible for increasing the rice production of Bangladesh from 8 million tonnes in 1965 to 20 million tonnes in 1975.
Ground-breaking cancer researcher Kamal Jayasing Ranadive (8 November 1917 – 11 April 2001) advanced the understanding of the causes of leukaemia, breast cancer and oesophageal cancer through the use of animal models. She was also among the first to recognise how susceptibility to cancer is linked to tumour-causing interactions between hormones and viruses.
Birbal Sahni (14 November 1891 – 10 April 1949), a pioneer of Indian palaeobotanical research, and founder of what is now the Birbal Sahni Institute of Palaeosciences in Lucknow, made multiple contributions to the study of prehistoric plants. These include the discovery of a new group of fossil gymnosperms (named Pentoxylae), reconstruction of the extinct Williamsonia sewardiana plant, and description of a new type of petrified wood from the Jurassic age.
Thai physician and conservationist Boonsong Lekagul (1907 – 1992) made major contributions to the preservation of his country’s wildlife.
Filipina chemist María Orosa (29 November 1892–13 February 1945) fought malnutrition and food insecurity in the Philippines by devising over 700 culinary creations including Soyalac, a nutrient rich drink made from soybeans, and Darak, rice cookies packed with Vitamin B1, which could prevent beriberi disease caused by Vitamin B1 deficiency. She was also a partisan of the guerrilla movement resisting Japanese occupation during World War II, and died after being struck by shrapnel while working in her laboratory during the Battle of Manila.
Eminent Filipina scientist and educator Clara Lim-Sylianco (18 August 1925 – 23 July 2013) is remembered for her extensive research on mutagens – often-carcinogenic agents that permanently alter genetic materials such as DNA – antimutagens and bioorganic mechanisms.
Chinese biochemist Cao Tianqin (5 December 1920 – 8 January 1995) discovered the myosin light chain, a subunit of myosin, a protein crucial for muscle contraction.
Research by Filipino plant scientist Benito Vergara (23 June 1934 – 24 October 2015) on the physiology of rice led to the development of deep-water and cold-tolerant rice varieties. Vergara also made several contributions to expanding public awareness of rice science.
In 1939, biochemist Kamala Sohonie (18 June 1911 – 28 June 1998) became the first woman to be accepted into the Indian Institute of Science (IISc).