Medicine & Healthcare

News

21 Jan 2022
A booster dose of the Pfizer–BioNTech vaccine (BNT162b2) against SARS-CoV-2 after an initial two doses of either the CoronaVac inactivated virus vaccine or Pfizer–BioNTech mRNA vaccine is shown to provide protection against the Omicron variant, in a pair of papers published in Nature Medicine.
19 Jan 2022
Researchers in Singapore and USA have developed a first-of-its-kind country ranking based on in-country experts’ ratings of the quality of palliative care services. The results reveal many countries have much room for improvement, including some high-income countries.
13 Jan 2022
The dengue virus alters mosquito behaviour in a way that makes it three times more efficient at transmitting infection.
Asia research News - Editor's Choice
10 Jan 2022
Unveiling substructures at the edge of the Galaxy, Nanodiamonds key to efficient hydrogen purification, How SARS-CoV-2 evades our immune system, A Zika hijacking with devastating impacts & Finding the right story for your audience, all in the January Editor's Choice.
Assoc. Prof. Dr. Salizar Binti Mohamed Ludin
31 Dec 2021
Researchers at International Islamic University Malaysia are investigating whether the prognosis of severe head injury patients improves with early surgical opening of the windpipe to help wean them off mechanical ventilation.
27 Dec 2021
Researchers from Osaka City University have shown in mice models of Alzheimer's disease, frontotemporal dementia, and dementia with Lewy bodies, that the intranasal administration of rifampicin and resveratrol in combination is safer and improves cognitive function more than rifampicin alone. The research results are expected to lead to the development of safe and effective nasal spray for the prevention of dementia.
23 Dec 2021
By searching for the protein transglutaminase 1 (TGM1) among patients with various autoimmune skin diseases, researchers have successfully identified a separate disease that can be linked to autoimmunity against TGM1. This backward method demonstrates a new way of identifying autoantigens as markers for various diseases. By letting autoantigens point to the disease, diagnosis and treatment can be facilitated, according to the study now published in PNAS.
Allergic reaction and immune tolerance mechanism
22 Dec 2021
Scientists have identified a series of molecular candidates for those parts of dog allergens that cause immune reactions in people—the first step in developing a vaccine against most causes of dog allergies.
22 Dec 2021
We have succeeded in establishing a mouse model that develops gastric cancer closely resembling advanced human gastric cancer. Using this model, we have discovered gastric cancer stem cells, i.e. Lgr5+ gastric cancer cells, essential for the development, maintenance, and metastasis of cancer. Our study provides an experimental system that enables detailed analysis of highly malignant gastric cancer and is expected to lead to the development of a breakthrough treatment for advanced human gastric cancer.
21 Dec 2021
In a study of 280 patients who underwent transcatheter aortic valve replacement (TAVI), researchers investigated the 3-year prognostic impact of frailty evaluated by the Kihon checklist (KCL), a survey originally developed to identify elderly individuals who were at risk of requiring support within the Japanese long-term care insurance system. Results showed that the estimated 3-year mortality rate was significantly higher in individuals who ranked high on the KCL, showcasing the checklist as a simple tool to be used alongside other surgical risk scores, in identifying patients who are too frail to benefit from TAVI
15 Dec 2021
In a recent study published in the Journal of Extracellular Vesicles researchers from Kanazawa University have visualized structural changes on the surface of SARS-CoV-2 that enable it to enter human cells.
14 Dec 2021
A prototype MRI machine that can be built at low cost and produces high quality neuroimaging is reported in Nature Communications. The machine can help provide access to MRI across low- and middle-income countries, as well as at the point of care.
Asia research News - Editor's Choice
09 Dec 2021
Micro-plastics cross blood brain barrier, Stomach cancer atlas, Omicron variant isolated, 120-year-old reaction turned on its head and Reporting through the coup, all in the December Editor's Choice. Plus our latest podcast: Decentralization and Democracy in Myanmar.
The expression of the immune response gene ​​NLRC5 (red purple) is suppressed in SARS-CoV-2 (green) infected cells (Photo: Ji-Seung Yoo, Koichi Kobayashi).
07 Dec 2021
Scientists at Hokkaido University and Texas A&M University have identified a key mechanism used by the SARS-CoV-2 virus to evade host immune systems.
Image of an ovarian granulosa cell tumor
03 Dec 2021
Examination of Japanese cases of gynecological cancer offers a better understanding of the profile of a rare ovarian tumor and could change treatment guidelines.
The first female doctor in Korea- Esther Park
02 Dec 2021
Giants in History: Esther Park (1877-1910), born Kim Jeom-dong, was the first female Korean physician to practise modern medicine in Korea.
Immunofluorescence staining of uninfected and infected Vero E6 cells
30 Nov 2021
Researchers at the Department of Microbiology at The University of Hong Kong have succeeded in the isolation of SARS-CoV-2 Omicron variant from clinical specimens. This is the first known research team in Asia that has succeeded in isolating the Omicron variant. The isolated variant will enable the development and production of vaccines against Omicron, which has been designated as a "variant of concern" by the World Health Organization.
24 Nov 2021
Researchers from the Osaka City University Graduate School of Medicine have shown in patients with early-stage hepatocellular carcinoma who received cancer treatment that eliminating the hepatitis C virus with a direct-acting antiviral treatment reduces the risk of the liver cancer progression and increases overall patient survival.
16 Nov 2021
Scientists are turning to genomics to better understand the epidemiology of malaria and to inform control and elimination interventions and strategies. In the Lake Victoria region of Kenya, malaria burden remains very high despite more than a decade of intense control activities. A team of researchers from Osaka City University, Nagasaki University, London School of Hygiene and Tropical Medicine, and Mount Kenya University generated whole Plasmodium falciparum genome sequences from the lake region. Their analyses revealed that malaria parasites from this region appear distinct from other parasites from East Africa, while frequencies of known drug resistance markers were similar to those in other East African parasite populations. Their findings will help to develop improved surveillance tools to determine parasite transmission routes and aid clinical disease management.
11 Nov 2021
Giants in History: A Japanese surgeon, Tetsuzo Akutsu (20 August 1922 – 9 August 2007) built the first artificial heart capable of keeping an animal alive.
08 Nov 2021
We have clarified at the molecular level the mechanism by which a microenvironment, a so-called niche that surrounds cancer cells, is formed in which stromal cells and immune cells are attracted at an initiation stage of breast cancer onset. A molecule called FRS2β is found to be critical for creating this microenvironment. The present finding is expected to be beneficial in prevention, diagnosis and treatment of cancers at the initiation stage.
Schematic of mechanistic mechanism by which EGFR activates YAP/TAZ
02 Nov 2021
Malfunctioning of the so-called Hippo signalling pathway within animal cells leads to irregular activity of proteins that regulate genes involved in cell proliferation. Researchers have identified a key step in the process of this aberration, opening the door to new therapeutics for cancers such as head-and-neck squamous cell carcinoma and lung adenocarcinoma.
02 Nov 2021
The world’s largest analysis of gastric tumour cells provides a launch pad for scientists to plan more effective therapies.
Dicentric chromosomes
29 Oct 2021
The new radiosensitivity biomarker can make way for chemoradiotherapy treatments tailored to each cancer patient in the future.
28 Oct 2021
A collaborative project between the Osaka City University Graduate Schools of Medicine and BioMedical Engineering Center (BMEC) revealed new bone formation in critical bone defects of animal model with an exposure to a pencil-type non-thermal atmospheric-pressure plasma at surgery.
27 Oct 2021
Researchers reveal correlation between ribotype (RT) strains of Cutibacterium acnes, which are found in human skin, and the lifespan of the nematode Caenorhabditis elegans. Strains RT4 and 8, which are associated with acne in human skin, shortened the lifespan of the nematode, while RT6, which are predominantly found in healthy human skin, did not. Also, it was found that the healthy skin-related RT6 strain of C. acnes improved C. elegans resistance to the pathogenic organism Staphylococcus aureus.
25 Oct 2021
Researchers have revealed in an animal model that ImmuBalance, a fermented soybean product, is effective in suppressing airway inflammation caused by asthma. Results showed a decreased presence of eosinophils in bronchoalveolar lavage fluid, a decrease in mucus production in the bronchial epithelium, and a suppression of proteins that induce eosinophilic inflammation.
Fe Villanueva del Mundo- The angel of Santo Tomas
20 Oct 2021
Giants in History: Fe Villanueva del Mundo (27 November 1911 – 6 August 2011) was a Filipina paediatrician who founded the Philippines’ first paediatric hospital. She graduated top of her class at the University of the Philippines, and in 1936 became the first female student to attend Harvard Medical School.
13 Oct 2021
Giants in History: Tsai-Fan Yu (1911 – 2 March 2007) was a Chinese-American physician and researcher who was the first female full professor at Mount Sinai School of Medicine.
13 Oct 2021
The El Niño Southern Oscillation (ENSO) could impact child nutrition in many countries in the tropics, a new study in Nature Communications suggests.

Events

17 Jan 2022 to 21 Jan 2022
World’s brightest minds converge at virtual summit to inspire young researchers and discuss key issues
25 Jan 2022 to 26 Jan 2022
With a brand-new focus, join us to explore Asia Healthcare Analytics Summit happening LIVE on 25 & 26 January 2022 via Hopin platform with 30+ Inspiring speakers, 100+ Virtual attendees, 4+ Networking session, 3+ Panel discussions of healthcare experts globally participating in this summit.
25 Nov 2021
Speakers from Singapore, India and Korea, invited to speak at Regional Webinar on virtual surgical planning in oral and facial surgery
11 Oct 2021 to 14 Oct 2021
Pandemics and Policy: Protecting Health and Promoting Economic Recovery
18 Oct 2021 to 19 Oct 2021
Now in its 14th installation, the HIMSS21 APAC Conference will converge under the theme of Future-Proof Healthcare: The Emergence of Asia Pacific.
12 Oct 2021 to 15 Oct 2021
The Asia's Largest Partnering “BioJapan” will be held both digitally and physically. Meet your potential business partners in this Partnering Event!
28 Sep 2021 to 30 Sep 2021
TECHINNOVATION is a premier technology-to-industry matching event presented by IPI. It brings together international technology providers and enterprises to accelerate the commercialisation of emerging technologies, seed licensing opportunities and foster open innovation collaborations.
07 Oct 2021 to 08 Oct 2021
The National Healthcare Group (NHG) is proud to present the 19th Edition of the Singapore Health & Biomedical Congress (SHBC).
07 Apr 2021 to 09 Apr 2021
Join us from 7 to 9 April 2021 at the Precision Public Health Asia 2021 Conference to find out how precision public health can improve health outcomes and equity to deliver ‘personalised’ public health.
24 Feb 2021 to 26 Feb 2021
INTERPHEX Week Osaka is Asia's leading exhibition for pharmaceutical industry, consists of 2 exhibitions for pharmaceutical technologies - INTERPHEX OSAKA (Manufacturing & Packaging) and PharmaLab Expo OSAKA (Pharma R&D and Drug Discovery).
12 Jan 2021 to 15 Jan 2021
Organised by the National Research Foundation – Prime Minister’s Office, Singapore, the ninth edition of the Global Young Scientists Summit ([email protected]) will take place 12 to 15 January 2021 as a virtual event.
23 Nov 2020 to 24 Nov 2020
Global health emergencies look set to be a part of our lives. What awaits us in 2021 and what lessons can we draw from COVID-19 coverage? How can we support newsrooms and journalists for more informed and impactful journalism about global scientific, technical and human challenges? What role does journalism play in seeking solutions for a better world that is both healthy, and sustainable?
18 Nov 2020 to 20 Nov 2020
The Asia-Pacific Agri-Food Innovation Summit will focus on accelerating innovation in supply chain resilience, urban food systems, alternative proteins, and affordable nutrition. Will you be joining the conversation virtually on November 18-20?
27 Nov 2020 to 28 Nov 2020
ACRLS 2020 aims to contribute to strengthening cooperation and relationship among members worldwide and forming a strong global network by providing various benefits to robotic clinics in rapidly growing nations throughout Asia.
10 Nov 2020 to 11 Nov 2020
A gathering of healthcare leaders, key government representatives and healthcare IT experts, this conference provides an exclusive platform for you to network with your important stakeholders in Singapore’s healthcare industry.
16 Nov 2020
Optimising Clinical Trials | Commercialising Great Science | Partnering for Growth
02 Nov 2020 to 06 Nov 2020
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
01 Oct 2020 to 02 Oct 2020
The 6th annual RNA Biology Symposium jointly organized by the RNA Biology Centre of CSI Singapore (NUS), Skin Research Institute of Singapore (A*STAR), Duke-NUS Medical School, School of Biological Sciences (NTU) and Singapore-MIT Alliance for Research and Technology (SMART)
10 Jul 2020
Tohoku University is hosting an online lecture on COVID-19 on July 10. Led by top virologist Hitoshi Oshitani, the panel will share the latest on the pandemic, and discuss how history, culture and religion can help us understand the challenges ahead.
26 Jun 2020
Flattening the Curve with Digital Health: Episode 7 - Australia
18 Jun 2020
Flattening the Curve with Digital Health: Episode 6 - Thailand
10 Jun 2020
Flattening the Curve with Digital Health: Episode 5 - Japan
04 Jun 2020
Flattening the Curve with Digital Health; Episode 4 - Malaysia
02 Sep 2020 to 04 Sep 2020
Celebrating and learning from COVID 19 success stories to shape new frontiers in patient experience, healthtech and innovation.
21 May 2020
Flattening the Curve with Digial Health - Episode 2: Singapore
28 May 2020
Flattening the Curve with Digital Health: Episode 3 - South Korea
14 May 2020
Flattening the Curve with Digital Health - Episode 1 - China
14 Oct 2020 to 16 Oct 2020
Asia's Premier Partnering Event for the Global Biotechnology Industry. This year’s exhibition will be held as originally planned at Pacifico Yokohama. BioJapan partnering is available both physically and virtually. Plus some seminars will be available online.
22 Jul 2020 to 26 Jul 2020
Due to the COVID-19 pandemic affecting international travel, this year's event will be a unique blend of online and live gatherings — BIO Asia–Taiwan 2020 Online + Live, to be held July 22-26 in Taipei, Taiwan.
09 Dec 2020 to 11 Dec 2020
Singapore's long-running Pharmaceutical Manufacturing Industry learning and networking event, featuring a stellar profile of C-suite experts and firms.

Researchers

Takashi Hashimoto's major expertise is clinical and basic research for both autoimmune bullous diseases and hereditary skin diseases.
Professor Chou has wide research interests in areas concerning geriatric psychiatry, elderly policies, population policy especially immigrant policy, poverty, welfare reform, income inequality and health policy.
Dr. Salizar Binti Mohamed Ludin is an Assoc. Prof at the Kulliyyah of Nursing of International Islamic University Malaysia.
Dr. Louisa Chung is a Registered Nutritionist of Association for Nutrition (UK) with ten years experience in weight management and physical fitness projects. She is now working on an innovative dietary intake method which aims better result in weight loss and nutrition education.
Dr. Akira Kaneko
Akira Kaneko was appointed as Professor of Parasitology of Osaka City University in 2010. Since then, he has conducted global health research with a particular focus on malaria elimination on islands in Vanuatu, Oceania and Lake Victoria, Kenya.
Dr. Esther Lau Yuet-ying
Dr Esther Lau specializes in clinical psychology and clinical neuropsychology. Currently, her primary line of research aims to uncover some of the complex relationships between sleep, emotional and cognitive functioning.
Jung Ah Cho
Jung Ah Cho is a Visiting Professor at the School of Undergraduate Studies, College of Transdisciplinary Studies, DGIST.
Prof. Hiromitsu Toyoda
Hiromitsu Toyoda is an associate professor at the Graduate School of Medicine of Osaka City University.
Kazuhisa Asai
Kazuhisa Asai is currently an associate professor at the Graduate School of Medicine of Osaka City University.
Tomoya Kawaguchi is a professor at Osaka City University. His top areas of expertise are Lung Cancer, Non-Small Cell Lung Cancer, EGFR Positive Lung Cancer, and Chronic Obstructive Pulmonary Disease.
Picture of Dr. Anna Kam Chi-shan
Dr.Anna Kam's research interests include advanced technologies in aural rehabilitation, automated hearing screening, tinnitus management and auditory processing.
Dr. Yuen has dual professional qualifications as an audiologist and a speech-language pathologist (or speech therapist). He is also an experienced cochlear implant clinical specialist audiologist.
Picture of Ann-Marie Chacko
Prof. Ann Marie Chacko lead the translational efforts for a portfolio of in vivo PET, SPECT, CT and optical imaging agents that span key therapeutic areas including oncology, immunology, infectious disease and neurobiology.
Prof. Patrick Tan's research focuses on developing genomic approaches to unlock the molecular and clinical diversity of gastric cancer (aka stomach cancer)- a leading cause of global cancer mortality.
Picture of Prof. David Bruce Matchar
Prof Matchar's research relates to clinical practice improvement - from the development of clinical policies to their implementation in real world clinical settings
Prof. Ooi Eng Eong
Professor Ooi Eng Eong is a clinician-scientist by training and his research on dengue is positioned at the interface between clinical epidemiology, virology and immunology. His laboratory is interested in how antibodies either protect against or enhance dengue virus infection and what viral factors influence epidemic dengue activity.
Yohei Kawano is currently and Associate Professor at the Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
Prof. Kiyomi Shitaoka's research aims to obtain effective antibody genes and T cell receptor genes by single-cell analysis of B cell and T cell receptors on lymphocytes. In addition, to apply these genes to develop new treatments for overcoming infectious diseases and cancer.
Prof. Tomoharu Yasuda
Prof. Tomoharu Yasuda's laboratory studies how immune system is regulated through the antigen receptor, intracellular signaling and lymphocyte programming.
Picture of Prof. Antonio Bertoletti
Prof. Antonio Bertoletti's current research focuses on the development of new immunological based therapies (TCR-redirected T cells, HLA-peptide specific antibodies) for the treatment of HBV and Hepatocellular carcinoma (HCC), and the characterization of human intra-sinusoidal hepatic immune system.
Picture of Anthony Tanoto Tan
Dr. Anthony Tan is actively involved in clinical trials in Singapore and China to test the safety and efficacy of adoptively transferring T cells engineered against HCC with HBV integration in collaboration with Lion TCR Pte Ltd.
Picture of Goh Bee Tin
Cl A/Prof Goh Bee Tin is Head and Senior Consultant in the Department of Oral and Maxillofacial Surgery (OMS), Research Director and Deputy Director (Research and Education) at the National Dental Centre of Singapore (NDCS)Education. Her research interests include bone tissue engineering and mandibular reconstruction.
Picture of Prof. Jan Schnupp
Prof. Jan is interested in how sensory processing interpret auditory inputs to the brain are transformed to underpin subjective perceptual qualities of sound such as pitch, timbre and sound source location, and how the brain learns to adapt to the statistical structure of the sounds in our environment to form efficient neural representations of sound and to support auditory scene analysis.
Picture of Hyeon- Ae Jeon
Prof. Hyeon- Ae Jeon is a principal investigator of Partner Group of the Max Planck Institute for Human Cognitive and Brain Sciences at the Department for Brain and Cognitive Sciences, DGIST.
Assoc Prof Dr Loh Siew Yim is a senior lecturer at the faculty of Medicine in University of Malaya, Malaysia Her research interest is cancer survivorship, and behavioural medicine .
Dr Paul Cliff Simon Divis is the director of Malaria Research Centre at Universiti Malaysia Sarawak (UNIMAS).
Yoon-Kyoung Cho is currently a group leader in the Center for Soft and Living Matter at the Institute for Basic Science (IBS) and a full professor in the Department of Biomedical Engineering at Ulsan National Institute of Science and Technology (UNIST) in the Republic of Korea.
Prof Yow is the Associate Head of the Humanities, Arts and Social Sciences at Singapore University of Technology and Design (SUTD) and leads the SUTD Language and Social Cognition Lab where they look at how language impacts on our cognitive functioning and understanding of the social world. Her research focuses on exploring and studying patterns of dual language use, how language environment may influence how children perceive communicative cues and how technology influences the way we communicate, and how it can be harnessed in ways that can improve or slow down the decline of cognition and social cognition.
David Virshup, M.D., is Director of the Programme in Cancer and Stem Cell Biology (CSCB) and Professor at Duke-NUS Medical School and is jointly appointed as Professor of Pediatrics at Duke University in North Carolina.
Eric Finkelstein is a Professor of the Programme in Health Services & Systems Research and the Executive Director of the Lien Centre for Palliative Care at the Duke-NUS Medical School, Singapore. He also holds appointments at NUS School of Public Health and Duke University Global Health Institute.