Medicine & Healthcare

News

20 Sep 2024
Researchers from Osaka University studied the neurological control applied to human walking that maintains the correct relationship between the leg positions. They found that the rhythm of each leg continues independently unless they become too far out of phase. This work can lead to better care for people who have difficulty walking due to age or neurological issues.
20 Sep 2024
A research team from Osaka University has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy. This discovery sheds light on the molecular pathways involved in autophagy and their implications for diseases such as cancer, neurodegenerative disorders, and aging-related conditions.
20 Sep 2024
A research group has developed a new COVID-19 testing system using Janus particles—microparticles with two sides possessing distinctive molecular properties. These particles are engineered to bind specifically to target antigens, such as viral proteins, creating a low-cost, accurate, and rapid means of testing for viral diseases. The system’s versatility means it can potentially be used to test for other diseases and biomarkers linked to other conditions.
COVID-19-associated pulmonary aspergillosis
19 Sep 2024
Incidence, risk factors found for pulmonary aspergillosis, an invasive fungal infection of lungs, among COVID-19 patients
Senior Research Fellow Ning Yilin (left) and Associate Professor Liu Nan discussing the gaps in the existing ethical discourse on GenAI applications in healthcare that informed their new checklist.
18 Sep 2024
An international consortium led by Duke-NUS Medical School introduces an ethics checklist for systematic and standardised assessment for research involving generative AI technologies in healthcare settings, enhancing accountability
18 Sep 2024
Researchers from Osaka University found that antibiotic-resistant bacteria are fatter and shorter than their antibiotic-sensitive parental strains, and that these morphological changes correlate with changes in the expression of genes related to energy metabolism and antibiotic resistance. A machine learning approach was able to distinguish between antibiotic-resistant and antibiotic-sensitive bacteria in the absence of drug treatment based on microscope images, suggesting that bioinformatics could be used to detect antibiotic resistance in patient samples.
17 Sep 2024
Learned society and publisher Applied Microbiology International (AMI) has announced a new partnership with science communicators SelectScience. The two organisations will be working together on SelectScience’s upcoming CLINICAL24 campaign and beyond.
17 Sep 2024
A recent study from Osaka University reveals that intensive diabetes treatment can improve periodontal disease inflammation. Researchers found that two weeks of intensive diabetes treatment under hospitalization for patients with type 2 diabetes significantly improved not only blood sugar control but also PISA, an indicator of gum disease inflammation. Furthermore, the improvement in PISA was related to factors such as insulin secretion capacity and the severity of diabetes complications and comorbidities before diabetes treatment. These findings suggest that early intervention in diabetes is crucial for improving gum disease in diabetic patients.
11 Sep 2024
Med-DDPM, a diffusion model, generates high-resolution 3D brain MRIs from masks, addressing data scarcity and privacy concerns in medical imaging.
11 Sep 2024
Researchers from Monash University and Osaka University find that administering regulatory T cells (Tregs) to a tissue injury can promote healing. The team locally treated mouse bone, muscle, and skin injuries with Tregs, resulting in significant tissue regeneration and wound healing compared with control treatments. Mechanistically, Tregs can promote tissue monocyte and macrophage switching to an anti-inflammatory state, specifically by secreting signaling molecules like interleukin-10. These data demonstrate the strong potential of using Tregs as a cell-based therapy for regenerative medicine.
For non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal for persons who might be overweight or obese.
09 Sep 2024
Whether immunotherapy or conventional chemotherapy carries less mortality risk depends on BMI
09 Sep 2024
Seaweed helps brain health, Whales in long-distance relationships, Jumpstarting male fertility, Demystifying black hole turbulence, Shrimp to steel & Mpox Resources. Read all in the latest Editor's Choice.
05 Sep 2024
Researchers from Osaka University have identified key immune cells that respond to the COVID-19 mRNA vaccination. These cells, known as activated atypical B cells, are increased in blood samples from people who have been vaccinated against COVID-19. Additionally, people with higher levels of these cells have more antibodies to fight the COVID-19 virus. These findings should help researchers assess how well people respond to the vaccine and help improve the design of new vaccines.
A graphical representation illustrates what might be occurring in undamaged and damaged skin.
04 Sep 2024
Suppression of an enzyme might allow melanocytes to recover
04 Sep 2024
A study highlights that children with ADHD frequently experience sleep problems, potentially linked to lower levels of melatonin, a hormone crucial for regulating sleep. Genetic variations that reduce melatonin levels at night are associated with more severe ADHD symptoms in children aged 8-9. The research suggests that improving sleep habits, such as increasing morning sunlight exposure and reducing evening screen time, could help manage ADHD symptoms. This underscores the importance of addressing sleep issues as a possible way to alleviate ADHD symptoms in children.
03 Sep 2024
Studied oxidative stress and Parkinson’s disease as a case study
Sterilization of cats and other companion animals, such as by removing the uterus, is a common procedure, with the donated uterus of cats providing the cells to generate feline induced pluripotent stem cells.
03 Sep 2024
Feeder-free induced pluripotent stem cells hold hope in therapies for cats’ chronic kidney disease
Digestive disorders and other life factors are found to contribute to chronic belching.
29 Aug 2024
Survey of 10,000 Japanese adults reveal leading causes of burp-related disorders
28 Aug 2024
Researchers from Osaka University found that voltage-sensing phosphatase (VSP) is activated by electrical signals during sperm maturation and is crucial for establishing the optimal phosphoinositide environment to generate functional spermatozoa. Modulating VSP function to promote appropriate sperm maturation could be used to develop clinical treatments for infertility in the future.
27 Aug 2024
A pioneering study titled “Causal effect of video gaming on mental well-being in Japan 2020-2022,” published in Nature Human Behaviour, has conducted the most comprehensive investigation to date on the causal relationship between video gaming and mental well-being. This research, the first to demonstrate this relationship using real-life data, challenges commonly held views about the effects of gaming.
Compounds from nucleic acids derived from salmon milt DNA and torula yeast RNA showed effects against cancer cell growth.
27 Aug 2024
Specific nucleosides hinder replication of tumor cells in step toward cancer prevention
Loss of Gα13 in ER+ breast cancer cells leads to increased cell growth and tumour development.
26 Aug 2024
The surprising discovery that cellular protein Gα13 may actually protect against—rather than promote growth of—the most commonly relapsing type of breast cancer signals potential for more effective and innovative treatments.
Compounds found in citrus and coconut could be the solution to oral disease in children and the elderly.
26 Aug 2024
A nonirritant, antibacterial solution to prevent oral inflammation may lie in citrus and coconut chemical compounds
The presidents of the three medical societies pose for a photo after signing a Memorandum of Understanding to renew the Alliance and reiterating their intention to collaborate closely, together with the signatories of the first MoU signed virtually in 2021 // Credit: Courtesy of TriMedSoc Alliance
23 Aug 2024
This alliance by the student bodies of Singapore’s three medical schools continues to unify and represent the voice of the local medical student community through regular dialogue, engagement and collaboration with external stakeholders, including the Singapore Medical Association and Ministry of Health.
Improvement effects of MOD06051. In the glomeruli of the disease group, neutrophils (green) that are positive for the NETs marker citrullinated histone H3 (Cit-H3; red) are observed. Cit-H3 was not observed in neutrophils infiltrating in the low-dose and high-dose treatment groups. (Yuka Nishibata, et al. Nature Communications. August 22, 2024)
22 Aug 2024
A newly developed compound that reduces harmful inflammation in rats caused by overactive neutrophils shows great potential as a safer treatment for various inflammatory diseases in humans.
Comparing the diagnostic accuracy of ChatGPT and radiologists
21 Aug 2024
ChatGPT’s diagnostic capabilities evaluated in comparison to radiologists
20 Aug 2024
Researchers from Osaka University developed an antibody that prevents the activation of the Dickkopf 1–Cytoskeleton-associated protein 4 (DKK1–CKAP4) pathway, which is important for tumor growth in several cancers, including pancreatic cancer. On the basis of an antibody derived from mice, the researchers developed an antibody that could be used in humans (Hv1Lt1). Hv1Lt1 successfully prevented tumor formation in experimental mice. When given in combination, it improved the effect of chemotherapy drugs.
20 Aug 2024
A clinical trial conducted by Tohoku University researchers has lead to the approval of a treatment for patients with a rare, muscle-weakening disease called GNE myopathy.
19 Aug 2024
Recent advances in medical science have complicated clinical decision-making, raising ethical issues. Hospitals have set up clinical ethics consultation systems, but their effectiveness is limited due to low awareness and communication difficulties. To address this, a research group initiated by Osaka University studied proactive ethics consultation practices, proposing strategies like “inter-professional ethics rounds" and "patient note reviews." These methods aim to resolve ethical issues, improve care, and alleviate moral dilemmas facing medical staff.
In the Drosophila brain, dormant neural stem cells with protrusions rich in actin filaments.
14 Aug 2024
Collaborative study by Duke-NUS and NUS Mechanobiology Institute offers new hope for treating neurodevelopmental disorders by activating dormant neural stem cells and uncovering other mechanisms behind brain development.

Events

09 Dec 2019 to 10 Dec 2019
The ASEAN Emerging Researchers Conference is a flagship programme of the ASEAN Young Scientists Network; the official platform for young researchers in the region.
08 Dec 2020 to 10 Dec 2020
Asia's pharma & biotech virtual festival - Phar-East is the premier meeting place for senior executives from Asia’s pharma and biotech industry.
26 Feb 2020 to 28 Feb 2020
Japan's Leading Exhibition for Pharmaceutical R&D and Manufacturing Technologies!
26 Nov 2019 to 27 Nov 2019
Vaccine World Asia 2019 will bring together leading experts to discuss the latest technological advancements and spearhead scientific innovation in the development and manufacture of vaccines for key diseases such as Dengue, Chikungunya, Malaria, Tuberculosis etc.
07 Nov 2019
Fostering Young Intellectuals for a Better Future
02 Oct 2019
Launching on 2nd October 2019 in Singapore
25 Sep 2019 to 26 Sep 2019
Vitafoods Asia is the dedicated event for Asia's nutraceutical, functional food and beverages, and dietary supplement industries, providing 350+ global suppliers to meet and do business with 6000+ visitors across the industry's four key areas from ingredient to shelf.
03 Oct 2019 to 04 Oct 2019
Deadline for online registration 20 September 2019! We are excited to host our 5th annual RNA Biology Symposium by the RNA Biology Centre of CSI Singapore, NUS. It will be held at the Clinical Research Centre (MD11) Auditorium, 10 Medical Drive, Singapore 117597.
20 Nov 2019 to 21 Nov 2019
Organising partner - the Australian Digital Health Agency
07 Oct 2019 to 10 Oct 2019
Tracks include: Sustainability & Growth; Patient Experience; Unlocking the Value of AI; Value-based Care.
24 Sep 2019 to 26 Sep 2019
The leading event that brings together Asia’s pharmaceutical companies and supplies all in one place
06 Nov 2019 to 07 Nov 2019
The 5th Annual Biopharma Development & Production Asia Pacific is back with a 360˙ view on industry trends, new therapies, technical innovation and many more.
04 Nov 2019 to 06 Nov 2019
We bring together distinguished cancer researchers with complementary knowledge and expertise from across the globe for the exchange of ideas and information.
14 Nov 2019 to 15 Nov 2019
The goal of this conference is to address the emerging technologies and themes in Microfluidics, Lab-on-a-Chip and Organ-on-a-Chip fields as these areas are expanding and evolving.
11 Nov 2019 to 12 Nov 2019
The conference addresses the whole ecosystem of Cell & Gene Therapy and 3D-Bioprinting with a focus on 3D-Culture, Organoids, Bioprinting and Technology Platforms being developed to bring cell therapy, gene therapy and regenerative medicine to the clinic.
09 Sep 2019 to 10 Sep 2019
This conference brings together a focus on technology development as well as applications for biomarker analysis in cancer, cardiovascular disease and other disease classes.
03 Jul 2019 to 05 Jul 2019
Asia's leading pharma industry event
09 Oct 2019 to 11 Oct 2019
Asia's Premier Partnering Event for the Global Biotechnology Industry

Researchers

David Virshup, M.D., is Director of the Programme in Cancer and Stem Cell Biology (CSCB) and Professor at Duke-NUS Medical School and is jointly appointed as Professor of Pediatrics at Duke University in North Carolina.
Eric Finkelstein is a Professor of the Programme in Health Services & Systems Research and the Executive Director of the Lien Centre for Palliative Care at the Duke-NUS Medical School, Singapore. He also holds appointments at NUS School of Public Health and Duke University Global Health Institute.
My PhD research entitled "No harm done? The experiences of women who inject drugs accessing harm reduction in Indonesia" examines the role of social, political and economic impacts on women who use/inject drugs and the correlation with increase rates of HIV/HCV and incarceration.
I am engaged in the development of a new device for embryo evaluation which measures embryo oxygen consumption and a new medication for infertility. Recently, I focused on causative genes of disorders of sex development and searched pathogenic variants using a whole-genome reference panel constructed by Tohoku Medical Megabank Organization.
I am an Assistant Professor in Health Services Policy and Management at the University of South Carolina Arnold School of Public Health, US. As a health services researcher and a rural health advocate, I am driven to advance rural health equity via productive, insightful research collaborations. My work applies global and hyper-local perspectives (rural-urban, county-level, state-level variations) building statistical models to examine rural healthcare delivery on outcomes, access, and welfare of women.
Linfa Wang
Professor Linfa Wang is a Professor with the Emerging Infectious Diseases Programme at Duke-NUS Medical School, Singapore.
Associate Professor Sophia Archuleta is the Head and Senior Consultant of the Division of Infectious Diseases at the National University Hospital, Singapore.
Ms. Mira Adhikari is a nursing faculty member on Pokhara Nursing Campus, Institute of Medicine, Tribhuvan University, Nepal. She has a rich experience of over 15 years in this profession.
Mangala Gunatilake is a veterinarian and professor at the Department of Physiology, Faculty of Medicine, University of Colombo, Sri Lanka.
Mais Aljunaidy
Dr. Mais Aljunaidy is an expert in women's mental health and an instructor at the Department of Psychology, Bilkent University, Turkey.
Dr NK Prasanna
Dr NK Prasanna is currently working as Sr. Scientist & Editor, Indian Journal of Biochemistry & Biophysics, Research Journals Division at CSIR-National Institute of Science Communication and Policy Research, New Delhi. Before joining CSIR (NIScPR), she was at IIT Guwahati. Dr Prasanna completed her Ph.D from Institute of Medical Sciences, Banaras Hindu University, Varanasi. In CSIR-NIScPR, She served one important flagship journals viz. Indian journal of Biochemistry and Biophysics (IJBB; ISSN: 0301-1208) It is pertinent to mention that the journal ranks first among all the NIScPR journals as per the available Journal Metrics by international agencies such as Thomson Reuters and Scopus. Details of remarkable academic achievements of IJBB which she spearheading, both nationally and globally. The Indian journal of Biochemistry and Biophysics (IJBB) is a premier SCI-indexed bimonthly peer-reviewed research journal that publishes original research articles in the subject area of biochemistry and biophysics
Dr Heo is currently a senior lecturer at the Department of Microbiology and Parasitology, Faculty of Medicine, Universiti Teknologi MARA, Malaysia.
Dr. Tazeen Jafar is a global health leader and expert with a focus on implementation research in hypertension, cardiovascular disease, and chronic kidney disease.
Prof. Wang Hongyan is the deputy programme director and principal investigator of the laboratory of Neural Stem Cell at Duke-NUS Medical School, Singapore.
Dr Ramli is a Professor at Department of Psychiatry, Kulliyyah of Medicine at the International Islamic University Malaysia (IIUM).
Ji-Won Lee is an assistant professor at the Faculty of Dental Medicine at Hokkaido University, Japan,
Tadahiro Iimura is a professor in the Faculty of Dental Medicine, the Division of Dental Medicine, the Department of Pathobiological Science, Hokkaido University, Japan
A professor at the Bone Regenerative Engineering Laboratory, Regenerative and Biomedical Engineering Division, Graduate School of Biomedical Engineering, Tohoku University, Japan
My research background covers multidisciplinary fields such as Pharmaceutics, Cancer Nanomedicine, Bioengineering and Organ-on-a-chip platforms. My current research focuses on the development of dynamic biological barriers on a chip such as blinking human cornea on a chip.
Infectious Disease Epidemiologist
Prof. Mahmudur Rahman is an Infectious Disease Epidemiologist. He is enlisted in the IHR roster of Experts and included in the Emergency committees of MERS CoV, Ebola and Poliomyelitis. He is also the Current Chair and member in different committees of WHO.
Hidemitsu Kitamura is an associate professor at the Section of Disease Control, the Institute for Genetic Medicine, Hokkaido University, Japan.
Professor Samuel Wong is a clinician with training in both Family Medicine and Public Health. He received his Doctor of Medicine degree from the University of Toronto and completed his Family Medicine residency training in Canada. He completed the Master of Public Health at the Johns Hopkins University, USA and the Doctor of Medicine (MD) research degree at The Chinese University of Hong Kong. ​ He is the Head of the Division of Family Medicine and Primary Healthcare and the Deputy Director of the School of Public Health and Primary Care since 2019. He has been the Co-Director of the Master of Public Health Programme since 2018 and is the Director of Thomas Jing Centre for Mindfulness Research and Training. He has also been appointed as the Associate Dean (Education) of the Faculty of Medicine since July 2019. ​ Professor Wong’s research interests include evaluating and developing mindfulness- based and mental health interventions in primary care; evaluating primary care services and developing primary care service models as well as multimorbidity.
Kartini Ilias is a senior lecturer and clinical psychologist in Faculty of Health Sciences, Universiti Teknologi MARA, Puncak Alam, Selangor.
Dr Kuan is currently a Professor and Consultant Haematologist at the Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak .
Professor, School of Life Sciences, The Chinese University of Hong Kong
Professor Tetsuya Kodama is a biomedical engineer at the Laboratory of Biomedical Engineering for Cancer, Graduate School of Biomedical Engineering, Tohoku University.
Aamir Jalal Al Mosawi is advisor in pediatrics and pediatric psychiatry at the Children Teaching Hospital of Baghdad Medical City.
Toru Kondo is Professor of the Division of Stem Cell Biology at the Institute for Genetic Medicine, Hokkaido University.
Ashley St. John
Prof. Ashley St. John is an expert in viral immunology and emerging infectious diseases, such as dengue and Zika viruses. She heads the Laboratory of Immunity and Immune Pathology at Duke-NUS Medical School.

Giants in history

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