Medicine & Healthcare
News
21 Jul 2024
Researchers from Osaka University interviewed Japanese women using oral contraceptives (OC) in Korea, revealing clinical and ethical issues faced by transnational patients. The study identified new health care types and highlighted differing perceptions of OC between patients and doctors upon returning to Japan, creating dilemmas. Ethical implications were proposed, and future access to patient-centered medicine and drug reclassification was investigated to improve SRHR issues in Japan.
16 Jul 2024
Combination of venetoclax and azacitidine helps patients with AML who relapse after hematopoietic cell transplant
12 Jul 2024
A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.
10 Jul 2024
Researchers from Japan discover a new enzyme with promising antibacterial activity
09 Jul 2024
First epidemiological study on incidence of EoE in Japan
08 Jul 2024
Potential benefits of method include subjecting patients to fewer exams and reducing health care costs
08 Jul 2024
Decoding dead stars’ “heartbeats”, Why do females live longer? DNA controller for molecular robots, Earliest twin quasars found. Read all in the latest Editor's Choice. Plus July's SciCom Coffee with A*STAR's Lisa Chong and get the early bird price to be in Asia Research News 2025.
02 Jul 2024
Osaka University researchers developed molecules, called splice-switching oligonucleotides (SSOs) that bind to the RNA molecules encoding a protein known as REST. In neuroendocrine tumors, these RNAs are incorrectly spliced together, which supports the cancerous phenotype. When injected into tumors in laboratory mice, SSOs could help restore normal REST function, leading to reduced tumor size. This novel approach is a promising new tool for treating neuroendocrine tumors that do not respond to conventional therapies.
01 Jul 2024
Results compare favorably with conventional microscopic method, with added benefit of shorter operative times, less blood loss
28 Jun 2024
Researchers from Osaka University have identified that the loss of the Men1 gene is key in the development of osteoporosis, fragile bones occurring with age. They developed a mouse model of age-related cellular aging, or ‘senescence’, in the bone for the first time. This showed that cellular senescence of bone-forming osteoblasts leads to osteoporosis due to an imbalance between the activities of bone formation and bone resorption, opening avenues for drug intervention and novel treatments.
20 Jun 2024
WSA's Office of Research in Clinical Amplification (ORCA) Asia will be a research laboratory dedicated to conducting audiological research for the Asian population.
12 Jun 2024
Researchers from Osaka University found that germ cells, which develop into eggs and sperm, drive sex-dependent differences in lifespan in vertebrates. Female and male germ cells increase and reduce lifespan, respectively. These effects are controlled via estrogen and growth factor hormones in females and vitamin D in males. Vitamin D supplementation extends lifespan in both males and females. The results clarify the link between reproduction and aging and show that vitamin D may improve longevity in vertebrates.
07 Jun 2024
Blue energy future, Off switch for brain cells, New Japanese lily species, Generative AI in motion, Economies take off with new airports and Braille-shaped electrodes for retinal implants. Read all in the latest Editor's Choice. Plus SciCom Coffee with Catriona Child.
05 Jun 2024
Osaka University researchers discovered a correlation between high GDF15 levels in steatotic liver patients and increased liver cancer risk. Steatotic liver disease cases, fueled by lifestyle-related issues, have surged globally, with Japan reporting a significant prevalence. Elevated GDF15 levels also signify complication risks associated with liver cirrhosis. Combining GDF15 levels and FIB-4 index aids efficient liver cancer detection, potentially improving prognosis through early intervention.
04 Jun 2024
Groundbreaking research from Duke-NUS offers new hope to millions with asthma and severe food allergies, signalling a new strategy for the prevention of life-threatening reactions.
01 Jun 2024
The largest graduating class in Duke-NUS’ history saw 90 graduates, including the first-ever Master of International Translational Medicine cohort, receive their degrees. Collectively, this cohort published 99 academic publications, underscoring Duke-NUS’ role as a leader in innovation and academic rigour in medical education. Celebrating diverse pathways to a career in healthcare, the graduates’ first degrees reflect diverse backgrounds, including architecture, communication studies and engineering, among others.
31 May 2024
Online group discussions, active learning help sustain healthy habits among countryside residents
30 May 2024
Research collaboration between Osaka University and Otsuka Pharmaceutical Co., Ltd. revealed that deletion of mRNA endonuclease Regnase-1 promoted NK cell anti-tumor activity via OCT2-dependent transcriptional up-regulation of Ifng mRNA. Associated with the deletion of Regnase-1 in NK cells, NK cells showed a high expression of OCT2 and CXCR6 in those that escaped from mRNA decay from Regnase-1, and they contributed to the transcriptional regulation of Ifng and NK cell persistence inside the tumor microenvironment, respectively. The loss-of-function strategy targeting Regnase-1 potentially enhances the production of cytotoxic proteins such as IFN-γ, granzymes, and perforin. This approach also promotes NK cell infiltration and persistence within the tumor, thereby facilitating the development of effective anti-tumor immunotherapy against solid tumors.
29 May 2024
A flexible two-layer polymer membrane allows safe, steady, and targeted release of a drug over weeks and months.
27 May 2024
Osaka University is starting a Phase I clinical trial (first in human) for refractory prostate cancer using an astatine-labeled drug ([At-211]PSMA-5). This trial aims to evaluate the safety, pharmacokinetics, and efficacy of the new alpha therapy. Previous trials for thyroid cancer have been successful. The trial addresses the high unmet needs of prostate cancer patients and leverages Japan's ability to manufacture astatine. This innovative therapy promises fewer side effects and no need for hospitalization, potentially benefiting patients globally.
27 May 2024
• International study, led by researchers in Singapore and Germany, unveils unexpected mechanisms of SGLT2 inhibitors, challenging the assumption that their beneficial, organ-protective effects stem from a diuretic effect.
• Insights suggest the drugs, which have been developed to treat diabetes but are meanwhile widely used for chronic kidney disease and heart failure, trigger ancient and highly conserved evolutionary survival signals that may also contribute to longer healthspans.
24 May 2024
New genetic tool developed by Duke-NUS could help investigate brain function and psychiatric disorders.
22 May 2024
Researchers from Osaka University have found that a specific pattern of brain activity, known as “sharp-wave ripples,” is associated with thoughts that wander from the present situation. This activity begins in the hippocampus, a crucial brain region for memory formation and recall, and is linked to more vivid and less desirable thoughts. A better understanding of the relationship between sharp-wave ripples and these kinds of thoughts might be helpful for treating related conditions.
22 May 2024
Novel real-time PCR method might become diagnostic tool targeting emerging bacterium responsible for food poisoning outbreaks
21 May 2024
Researchers at Osaka University analyzed data from the Japan Gerontological Evaluation Study and found that socioeconomic status (SES) transitions affect dementia risk. Specifically, upward SES mobility is greater associated with reduced dementia risk and extended healthy aging with dementia-free lifespan, while downward mobility increases risk. The study of 9,186 participants found that lifestyle, comorbidities, and social factors mediate this relationship, highlighting the importance of SES in cognitive health and preventing dementia.
20 May 2024
Promising results of helium plasma jet therapy on rats after surgery widen scope of method’s medical applications
17 May 2024
Researchers from Osaka University found that the tyrosine kinase Csk plays a crucial role in regulating germinal center B cell signaling. Csk deletion in a mouse model led to increased ROS production and apoptosis, thereby inhibiting B cell affinity maturation.
10 May 2024
Researchers from Osaka University have used a novel combination of short-read and long-read RNA sequencing to identify the different isoforms of genes expressed in the crustacean Daphnia magna. Males and females are genetically identical, but using this technique the team revealed genes that switch the predominant isoform in a sex-dependent manner. This study contributes to our understanding of Daphnia’s sexual dimorphism and helps further advance technologies in crustacean aquaculture.
08 May 2024
Researchers undertook a study of older adults to examine the connection between a sense of economic insecurity and a person’s participation in social activities.
02 May 2024
Osaka University researchers discovered a concerning association between bacteremia and probiotic use, particularly with Clostridium butyricum (C. butyricum) MIYAIRI 588. Whole-genome sequencing revealed that all C. butyricum bacteremia strains were probiotic derivatives. Out of 6,576 cases of positive blood cultures, C. butyricum was detected in only five cases, all derived from probiotics. The study underscores rare but serious adverse events linked to probiotics, advocating cautious prescribing practices, especially for hospitalized patients.
Events
11 Oct 2021 to 14 Oct 2021
Pandemics and Policy: Protecting Health and Promoting Economic Recovery
18 Oct 2021 to 19 Oct 2021
Now in its 14th installation, the HIMSS21 APAC Conference will converge under the theme of Future-Proof Healthcare: The Emergence of Asia Pacific.
12 Oct 2021 to 15 Oct 2021
The Asia's Largest Partnering “BioJapan” will be held both digitally and physically. Meet your potential business partners in this Partnering Event!
28 Sep 2021 to 30 Sep 2021
TECHINNOVATION is a premier technology-to-industry matching event presented by IPI. It brings together international technology providers and enterprises to accelerate the commercialisation of emerging technologies, seed licensing opportunities and foster open innovation collaborations.
07 Oct 2021 to 08 Oct 2021
The National Healthcare Group (NHG) is proud to present the 19th Edition of the Singapore Health & Biomedical Congress (SHBC).
07 Apr 2021 to 09 Apr 2021
Join us from 7 to 9 April 2021 at the Precision Public Health Asia 2021 Conference to find out how precision public health can improve health outcomes and equity to deliver ‘personalised’ public health.
24 Feb 2021 to 26 Feb 2021
INTERPHEX Week Osaka is Asia's leading exhibition for pharmaceutical industry, consists of 2 exhibitions for pharmaceutical technologies - INTERPHEX OSAKA (Manufacturing & Packaging) and PharmaLab Expo OSAKA (Pharma R&D and Drug Discovery).
12 Jan 2021 to 15 Jan 2021
Organised by the National Research Foundation – Prime Minister’s Office, Singapore, the ninth edition of the Global Young Scientists Summit (GYSS@one-north) will take place 12 to 15 January 2021 as a virtual event.
23 Nov 2020 to 24 Nov 2020
Global health emergencies look set to be a part of our lives. What awaits us in 2021 and what lessons can we draw from COVID-19 coverage? How can we support newsrooms and journalists for more informed and impactful journalism about global scientific, technical and human challenges? What role does journalism play in seeking solutions for a better world that is both healthy, and sustainable?
18 Nov 2020 to 20 Nov 2020
The Asia-Pacific Agri-Food Innovation Summit will focus on accelerating innovation in supply chain resilience, urban food systems, alternative proteins, and affordable nutrition. Will you be joining the conversation virtually on November 18-20?
27 Nov 2020 to 28 Nov 2020
ACRLS 2020 aims to contribute to strengthening cooperation and relationship among members worldwide and forming a strong global network by providing various benefits to robotic clinics in rapidly growing nations throughout Asia.
10 Nov 2020 to 11 Nov 2020
A gathering of healthcare leaders, key government representatives and healthcare IT experts, this conference provides an exclusive platform for you to network with your important stakeholders in Singapore’s healthcare industry.
16 Nov 2020
Optimising Clinical Trials | Commercialising Great Science | Partnering for Growth
02 Nov 2020 to 06 Nov 2020
We invite scientists, doctors, students and other delegates engaging in scientific research related to cancer to join us at Singapore’s preferred cancer conference.
01 Oct 2020 to 02 Oct 2020
The 6th annual RNA Biology Symposium jointly organized by the RNA Biology Centre of CSI Singapore (NUS), Skin Research Institute of Singapore (A*STAR), Duke-NUS Medical School, School of Biological Sciences (NTU) and Singapore-MIT Alliance for Research and Technology (SMART)
10 Jul 2020
Tohoku University is hosting an online lecture on COVID-19 on July 10. Led by top virologist Hitoshi Oshitani, the panel will share the latest on the pandemic, and discuss how history, culture and religion can help us understand the challenges ahead.
26 Jun 2020
Flattening the Curve with Digital Health: Episode 7 - Australia
18 Jun 2020
Flattening the Curve with Digital Health: Episode 6 - Thailand
10 Jun 2020
Flattening the Curve with Digital Health: Episode 5 - Japan
04 Jun 2020
Flattening the Curve with Digital Health; Episode 4 - Malaysia
02 Sep 2020 to 04 Sep 2020
Celebrating and learning from COVID 19 success stories to shape new frontiers in patient experience, healthtech and innovation.
21 May 2020
Flattening the Curve with Digial Health - Episode 2: Singapore
28 May 2020
Flattening the Curve with Digital Health: Episode 3 - South Korea
14 May 2020
Flattening the Curve with Digital Health - Episode 1 - China
14 Oct 2020 to 16 Oct 2020
Asia's Premier Partnering Event for the Global Biotechnology Industry. This year’s exhibition will be held as originally planned at Pacifico Yokohama. BioJapan partnering is available both physically and virtually. Plus some seminars will be available online.
22 Jul 2020 to 26 Jul 2020
Due to the COVID-19 pandemic affecting international travel, this year's event will be a unique blend of online and live gatherings — BIO Asia–Taiwan 2020 Online + Live, to be held July 22-26 in Taipei, Taiwan.
09 Dec 2020 to 11 Dec 2020
Singapore's long-running Pharmaceutical Manufacturing Industry learning and networking event, featuring a stellar profile of C-suite experts and firms.
03 Nov 2020 to 05 Nov 2020
Your go-to event to reach out to key decision makers in the pharmaceutical industry. The event will be delivered digitally from 3-5 November 2020.
17 Jul 2020 to 18 Jul 2020
Asia’s annual premier healthcare platform CAREhab 2020 and conference element 6th Singapore Rehabilitation Conference, will now be held online on the 17 – 18 July 2020.
07 Jul 2020 to 08 Jul 2020
IMAPAC is bringing to you 3 focus areas: Bio-Manufacturing, Bio-Analytics, and Cell Therapy Bioprocessing as part of Asia's biggest, most focussed annual bioprocessing virtual conference!
Researchers
Takashi Hashimoto's major expertise is clinical and basic research for both autoimmune bullous diseases and hereditary skin diseases.
Professor Chou has wide research interests in areas concerning geriatric psychiatry, elderly policies, population policy especially immigrant policy, poverty, welfare reform, income inequality and health policy.
Dr. Salizar Binti Mohamed Ludin is an Assoc. Prof at the Kulliyyah of Nursing of International Islamic University Malaysia.
Dr. Louisa Chung is a Registered Nutritionist of Association for Nutrition (UK) with ten years experience in weight management and physical fitness projects. She is now working on an innovative dietary intake method which aims better result in weight loss and nutrition education.
Akira Kaneko was appointed as Professor of Parasitology of Osaka City University in 2010. Since then, he has conducted global health research with a particular focus on malaria elimination on islands in Vanuatu, Oceania and Lake Victoria, Kenya.
Dr Esther Lau specializes in clinical psychology and clinical neuropsychology. Currently, her primary line of research aims to uncover some of the complex relationships between sleep, emotional and cognitive functioning.
Jung Ah Cho is a Visiting Professor at the School of Undergraduate Studies, College of Transdisciplinary Studies, DGIST.
Hiromitsu Toyoda is an associate professor at the Graduate School of Medicine of Osaka City University.
Kazuhisa Asai is currently an associate professor at the Graduate School of Medicine of Osaka City University.
Tomoya Kawaguchi is a professor at Osaka City University. His top areas of expertise are Lung Cancer, Non-Small Cell Lung Cancer, EGFR Positive Lung Cancer, and Chronic Obstructive Pulmonary Disease.
Dr.Anna Kam's research interests include advanced technologies in aural rehabilitation, automated hearing screening, tinnitus management and auditory processing.
Dr. Yuen has dual professional qualifications as an audiologist and a speech-language pathologist (or speech therapist). He is also an experienced cochlear implant clinical specialist audiologist.
Prof. Ann Marie Chacko lead the translational efforts for a portfolio of in vivo PET, SPECT, CT and optical imaging agents that span key therapeutic areas including oncology, immunology, infectious disease and neurobiology.
Prof. Patrick Tan's research focuses on developing genomic approaches to unlock the molecular and clinical diversity of gastric cancer (aka stomach cancer)- a leading cause of global cancer mortality.
Prof Matchar's research relates to clinical practice improvement - from the development of clinical policies to their implementation in real world clinical settings
Professor Ooi Eng Eong is a clinician-scientist by training and his research on dengue is positioned at the interface between clinical epidemiology, virology and immunology. His laboratory is interested in how antibodies either protect against or enhance dengue virus infection and what viral factors influence epidemic dengue activity.
Yohei Kawano is currently and Associate Professor at the Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
Prof. Kiyomi Shitaoka's research aims to obtain effective antibody genes and T cell receptor genes by single-cell analysis of B cell and T cell receptors on lymphocytes. In addition, to apply these genes to develop new treatments for overcoming infectious diseases and cancer.
Prof. Tomoharu Yasuda's laboratory studies how immune system is regulated through the antigen receptor, intracellular signaling and lymphocyte programming.
Prof. Antonio Bertoletti's current research focuses on the development of new immunological based therapies (TCR-redirected T cells, HLA-peptide specific antibodies) for the treatment of HBV and Hepatocellular carcinoma (HCC), and the characterization of human intra-sinusoidal hepatic immune system.
Dr. Anthony Tan is actively involved in clinical trials in Singapore and China to test the safety and efficacy of adoptively transferring T cells engineered against HCC with HBV integration in collaboration with Lion TCR Pte Ltd.
Cl A/Prof Goh Bee Tin is Head and Senior Consultant in the Department of Oral and Maxillofacial Surgery (OMS), Research Director and Deputy Director (Research and Education) at the National Dental Centre of Singapore (NDCS)Education. Her research interests include bone tissue engineering and mandibular reconstruction.
Prof. Jan is interested in how sensory processing interpret auditory inputs to the brain are transformed to underpin subjective perceptual qualities of sound such as pitch, timbre and sound source location, and how the brain learns to adapt to the statistical structure of the sounds in our environment to form efficient neural representations of sound and to support auditory scene analysis.
Prof. Hyeon- Ae Jeon is a principal investigator of Partner Group of the Max Planck Institute for Human Cognitive and Brain Sciences at the Department for Brain and Cognitive Sciences, DGIST.
Dr Yap is currently a senior lecturer and course coordinator for the Bachelor of Medical Bioscience at Monash University Malaysia. She is dedicated to toxin pharmacology and toxicology research. She has strong background in biomolecular modelling, proteomics, immunological and molecular pharmacology of bioactive toxins. She leads the Toxin Pharmacology Research Group. Her research group now focuses on molecular mechanisms of cytotoxin with the ultimate goal of developing next-generation biotherapeutics. Her research works have been featured in prominent media outlets, including the International Snakebite Awareness Day campaign. Besides active in research, she is also an education innovator who adopts various active learning strategies with technology. She teaches undergraduate units with an emphasis on student-cantered learning using the andragogy approach. Dr Michelle enjoys promoting STEM education to the public. She has organized and hosted several workshops and forums to advance the disciplines in medical sciences through research and education.
Assoc Prof Dr Loh Siew Yim is a senior lecturer at the faculty of Medicine in University of Malaya, Malaysia
Her research interest is cancer survivorship, and behavioural medicine .
Dr Paul Cliff Simon Divis is the director of Malaria Research Centre at Universiti Malaysia Sarawak (UNIMAS).
Yoon-Kyoung Cho is currently a group leader in the Center for Soft and Living Matter at the Institute for Basic Science (IBS) and a full professor in the Department of Biomedical Engineering at Ulsan National Institute of Science and Technology (UNIST) in the Republic of Korea.
Prof Yow is the Associate Head of the Humanities, Arts and Social Sciences at Singapore University of Technology and Design (SUTD) and leads the SUTD Language and Social Cognition Lab where they look at how language impacts on our cognitive functioning and understanding of the social world. Her research focuses on exploring and studying patterns of dual language use, how language environment may influence how children perceive communicative cues and how technology influences the way we communicate, and how it can be harnessed in ways that can improve or slow down the decline of cognition and social cognition.
David Virshup, M.D., is Director of the Programme in Cancer and Stem Cell Biology (CSCB) and Professor at Duke-NUS Medical School and is jointly appointed as Professor of Pediatrics at Duke University in North Carolina.
Giants in history
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