Medicine & Healthcare
02 Feb 2023
Researchers from Osaka University have used single carbon atom doping to form four chemical bonds in one step. Gamma-lactams (cyclic molecules that are common in antibiotics) were easily synthetically accessible from alpha, beta-unsaturated amides (an important molecule in cancer progression). The team chemically modified an anti-seizure medication in 96% yield, highlighting the work's utility to otherwise synthetically complex aspects of pharmaceutical development. The results of this work could become foundational to drug discovery and development.
02 Feb 2023
Blocking an immune-regulating protein reverses the damage caused by acute and chronic kidney disease, a preclinical study suggests.
02 Feb 2023
A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.
30 Jan 2023
Researchers from Osaka University compared the sensitivity of rapid antigen tests (RATs) and polymerase chain reaction (PCR) tests for the Omicron variant of COVID-19 using data produced by the Japan Professional Football League. They found the comparative sensitivity of RATs for Omicron was not affected by the duration from the onset of symptoms to testing.
27 Jan 2023
New research found that periodontitis, a common gum infection known to worsen other systemic diseases, could also be linked to atrial fibrosis — potentially clarifying its previously unknown connection with atrial fibrillation.
23 Jan 2023
New research from Osaka University indicates that more screen time at age 2 is associated with poorer communication and daily living skills at age 4—but when kids also play outdoors, some of the negative effects of screen time are reduced. Increasing outdoor play time could reduce the negative effects of screen time on daily living skills by almost 20%.
20 Jan 2023
Overeating mechanism: why "eating just one chip"🍟 is impossible, Measuring hidden energy of gamma-ray bursts, Marine species that can adapt to ocean acidification & A rough start can lead to a strong bond, Read all in our first Editor's Choice of 2023. Plus our interview on what dengue vaccine approval in EU💉means for global dengue protection.
17 Jan 2023
In a study recently published in Cancer Science researchers from Kanazawa University show how some intestinal cancer cells lose their ability to spread as they divide and can be eliminated as the cancer grows.
13 Jan 2023
Researchers led by Osaka University demonstrated the role of endothelial cell-specific protein Roundabout4 (Robo4) in the reduction of vascular permeability and mortality in mouse models of severe infection. The research team identified a drug inhibitor that increased Robo4 expression and reduced mortality in sepsis and SARS-CoV-2 mouse models of infection. These findings may aid in the development of drugs to reduce the mortality rate of severe infectious diseases.
12 Jan 2023
An Osaka Metropolitan University research group recorded the autonomic nervous system activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology.
11 Jan 2023
Osaka Metropolitan University scientists delved into the relationship between gait function and knee extension velocity after total knee arthroplasty and compared the effects of various factors on walking. The results reveal that knee extension velocity, measured while seated, on the operated side was the most important determinant of gait function. These findings are expected to contribute to the development of new rehabilitation programs for efficient gait function improvement.
05 Jan 2023
Researchers at Hokkaido University have revealed the effects of high pathogenicity avian influenza virus infection on an Ezo red fox and a Japanese raccoon dog, linking their infection to a recorded die-off of crows.
04 Jan 2023
A research study led by scientists from the School of Chinese Medicine (SCM) at Hong Kong Baptist University (HKBU) has shown for the first time that the human gut bacterium Ruminococcus gnavus is a major trigger factor of diarrhoea-predominant irritable bowel syndrome (IBS-D). Based on this discovery, a new therapeutic target for the disease’s treatment was identified. The study also found that low-protein food items such as fresh fruits, vegetables and bread may help reduce the gut motility in IBS-D.
04 Jan 2023
Researchers from Osaka University found that dietary supplementation with tricaprin results in coronary artery plaque regression and resolution of symptoms in patients with triglyceride deposit cardiomyovasculopathy, a treatment-resistant form of coronary artery disease. These findings represent a conceptually novel treatment for coronary atherosclerosis that paves the way toward establishing a multi-faceted approach to caring for patients with this condition.
23 Dec 2022
Scientists reveal genetic mechanism associated with high-calorie food-fueled obesity
23 Dec 2022
The ability to see what’s happening inside the body in real-time and at a high resolution is a capability that ultrasound grants orthopedists at a low cost to patients. Ultrasound-guided diagnosis, however, remains relatively new in the field. Dr. Yuko Nakashima is here to change that for Japan with the help of her fellow “e-girls.”
22 Dec 2022
A research team led by Osaka Metropolitan University has revealed a difference in neural activity in response to visual food stimuli, depending on whether those stimuli are presented consciously or unconsciously. Using a questionnaire to assess the study participants, the team found that this difference was associated with their scores on eating behaviors, including emotional eating and cognitive restraint of food intake. These results indicate that eating behavior cannot be understood without taking into account both unconscious and conscious neural processes.
20 Dec 2022
Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.
19 Dec 2022
Researchers from Osaka University found that the “belief in just deserts”, which is the idea that infected individual deserves to be infected, was associated with attitudes about government restrictions during public health emergencies in the context of the COVID-19 global pandemic. This information could lead to new strategies for combating discrimination, prejudice, and stigma against COVID-19 patients.
19 Dec 2022
A research team led by Hong Kong Baptist University (HKBU) has identified a molecular target for bone anabolic therapies using a selected aptamer that serves as an inhibitor of sclerostin, a protein that prevents bone growth. The discovery offers hope for the development of an effective next-generation treatment for osteoporosis and osteogenesis imperfecta that is free of cardiovascular risk compared to the marketed antibody drug.
19 Dec 2022
An Osaka Metropolitan University scientist measured the light transmittance of the eyelids when the eyes are closed, and found that perceived closed-eye brightness is significantly stronger than previously reported. The influence of color was also observed, with red light perceived as brighter and blue light perceived as darker. Additionally, there were significant differences between experimental participants; for some, their perception of brightness barely differed between open- and closed-eye conditions.
16 Dec 2022
Scientists developed a novel device that predicts whether an ICU patient taken off mechanical ventilation is likely to suffer from respiratory emergencies, helping critical care teams to provide immediate life-saving interventions.
15 Dec 2022
Researchers led by Osaka University report the development of INCIDER, a fluorescent sensor system that enables high-contrast microscopic imaging of temporal changes in cellular interactions mediated by the N-cadherin molecule. This sensor system, which emits much brighter fluorescence than the currently used system while detecting these interactions, is expected to have a wide range of applications in developmental biology, neuroscience, and other fields.
14 Dec 2022
Researchers led by Osaka University generated a time-stamping method to trace the development and survival of plasma cells in the bone marrow and spleen. Using a mouse model in which plasma cells were fluorescently labeled in an inducible manner, they found that plasma cells were continuously replenished by new cells, a small portion of which differentiated into long-lived plasma cells (LLPCs). These findings may aid in the development of new vaccines that efficiently induce LLPCs.
13 Dec 2022
A study by Osaka University has shown that the prevalence of non-communicable diseases, which included hypertension, hyperlipidemia, diabetes, and mental disorders, increased after the Fukushima disaster and the COVID-19 outbreak. These findings emphasize the importance of improving post-disaster health promotion strategies and recommendations.
09 Dec 2022
− The European Commission Approved QDENGA (TAK-003) for Use in Individuals Four Years of Age and Older [i] − QDENGA Becomes the Only Dengue Vaccine Approved in the EU for Use in Individuals Regardless of Previous Dengue Exposure [i]
08 Dec 2022
Quinine and various drugs based on its chemical structure have been used to treat malaria for centuries. But parasites resistant to antimalarial drugs are becoming apparent. To pave the way for future medicine development, an efficient way to synthesize quinine was needed. And now a research team from Tohoku University has achieved just that.
06 Dec 2022
World's first research into relationship between rich-in-biodiversity garden greenery and health/well-being launched by University of Tokyo and Sekisui House Ltd.
01 Dec 2022
Therapeutically superior mesenchymal stem cells derived from the cranial bone offer hope in reversing paralysis and language impairment in moderate to severe cases of stroke.
25 Nov 2022
Researchers led by Osaka University identified plasma proteins associated with critical pathogenesis in COVID-19. Using a novel blood proteomics method, the researchers evaluated two discovery cohorts and one validation cohort of patients with COVID-19 and healthy volunteers. Cell adhesion proteins WFDC2, GDF15, CHI3L1, and KRT19 were shown to be associated with disease severity in patients with COVID-19, and may serve as potential targets for therapies to treat COVID-19 infection.
04 Jun 2020
Flattening the Curve with Digital Health; Episode 4 - Malaysia
02 Sep 2020 to 04 Sep 2020
Celebrating and learning from COVID 19 success stories to shape new frontiers in patient experience, healthtech and innovation.
21 May 2020
Flattening the Curve with Digial Health - Episode 2: Singapore
28 May 2020
Flattening the Curve with Digital Health: Episode 3 - South Korea
14 May 2020
Flattening the Curve with Digital Health - Episode 1 - China
14 Oct 2020 to 16 Oct 2020
Asia's Premier Partnering Event for the Global Biotechnology Industry. This year’s exhibition will be held as originally planned at Pacifico Yokohama. BioJapan partnering is available both physically and virtually. Plus some seminars will be available online.
22 Jul 2020 to 26 Jul 2020
Due to the COVID-19 pandemic affecting international travel, this year's event will be a unique blend of online and live gatherings — BIO Asia–Taiwan 2020 Online + Live, to be held July 22-26 in Taipei, Taiwan.
09 Dec 2020 to 11 Dec 2020
Singapore's long-running Pharmaceutical Manufacturing Industry learning and networking event, featuring a stellar profile of C-suite experts and firms.
03 Nov 2020 to 05 Nov 2020
Your go-to event to reach out to key decision makers in the pharmaceutical industry. The event will be delivered digitally from 3-5 November 2020.
17 Jul 2020 to 18 Jul 2020
Asia’s annual premier healthcare platform CAREhab 2020 and conference element 6th Singapore Rehabilitation Conference, will now be held online on the 17 – 18 July 2020.
07 Jul 2020 to 08 Jul 2020
IMAPAC is bringing to you 3 focus areas: Bio-Manufacturing, Bio-Analytics, and Cell Therapy Bioprocessing as part of Asia's biggest, most focussed annual bioprocessing virtual conference!
09 Dec 2019 to 10 Dec 2019
The ASEAN Emerging Researchers Conference is a flagship programme of the ASEAN Young Scientists Network; the official platform for young researchers in the region.
08 Dec 2020 to 10 Dec 2020
Asia's pharma & biotech virtual festival - Phar-East is the premier meeting place for senior executives from Asia’s pharma and biotech industry.
26 Feb 2020 to 28 Feb 2020
Japan's Leading Exhibition for Pharmaceutical R&D and Manufacturing Technologies!
26 Nov 2019 to 27 Nov 2019
Vaccine World Asia 2019 will bring together leading experts to discuss the latest technological advancements and spearhead scientific innovation in the development and manufacture of vaccines for key diseases such as Dengue, Chikungunya, Malaria, Tuberculosis etc.
07 Nov 2019
Fostering Young Intellectuals for a Better Future
02 Oct 2019
Launching on 2nd October 2019 in Singapore
25 Sep 2019 to 26 Sep 2019
Vitafoods Asia is the dedicated event for Asia's nutraceutical, functional food and beverages, and dietary supplement industries, providing 350+ global suppliers to meet and do business with 6000+ visitors across the industry's four key areas from ingredient to shelf.
03 Oct 2019 to 04 Oct 2019
Deadline for online registration 20 September 2019! We are excited to host our 5th annual RNA Biology Symposium by the RNA Biology Centre of CSI Singapore, NUS. It will be held at the Clinical Research Centre (MD11) Auditorium, 10 Medical Drive, Singapore 117597.
20 Nov 2019 to 21 Nov 2019
Organising partner - the Australian Digital Health Agency
07 Oct 2019 to 10 Oct 2019
Tracks include: Sustainability & Growth; Patient Experience; Unlocking the Value of AI; Value-based Care.
24 Sep 2019 to 26 Sep 2019
The leading event that brings together Asia’s pharmaceutical companies and supplies all in one place
06 Nov 2019 to 07 Nov 2019
The 5th Annual Biopharma Development & Production Asia Pacific is back with a 360˙ view on industry trends, new therapies, technical innovation and many more.
04 Nov 2019 to 06 Nov 2019
We bring together distinguished cancer researchers with complementary knowledge and expertise from across the globe for the exchange of ideas and information.
13 Aug 2019 to 14 Aug 2019
Call for participation. Deadline: 30 April 2019
14 Nov 2019 to 15 Nov 2019
The goal of this conference is to address the emerging technologies and themes in Microfluidics, Lab-on-a-Chip and Organ-on-a-Chip fields as these areas are expanding and evolving.
11 Nov 2019 to 12 Nov 2019
The conference addresses the whole ecosystem of Cell & Gene Therapy and 3D-Bioprinting with a focus on 3D-Culture, Organoids, Bioprinting and Technology Platforms being developed to bring cell therapy, gene therapy and regenerative medicine to the clinic.
09 Sep 2019 to 10 Sep 2019
This conference brings together a focus on technology development as well as applications for biomarker analysis in cancer, cardiovascular disease and other disease classes.
Prof Matchar's research relates to clinical practice improvement - from the development of clinical policies to their implementation in real world clinical settings
Professor Ooi Eng Eong is a clinician-scientist by training and his research on dengue is positioned at the interface between clinical epidemiology, virology and immunology. His laboratory is interested in how antibodies either protect against or enhance dengue virus infection and what viral factors influence epidemic dengue activity.
Yohei Kawano is currently and Associate Professor at the Department of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University.
Prof. Kiyomi Shitaoka's research aims to obtain effective antibody genes and T cell receptor genes by single-cell analysis of B cell and T cell receptors on lymphocytes. In addition, to apply these genes to develop new treatments for overcoming infectious diseases and cancer.
Prof. Tomoharu Yasuda's laboratory studies how immune system is regulated through the antigen receptor, intracellular signaling and lymphocyte programming.
Prof. Antonio Bertoletti's current research focuses on the development of new immunological based therapies (TCR-redirected T cells, HLA-peptide specific antibodies) for the treatment of HBV and Hepatocellular carcinoma (HCC), and the characterization of human intra-sinusoidal hepatic immune system.
Dr. Anthony Tan is actively involved in clinical trials in Singapore and China to test the safety and efficacy of adoptively transferring T cells engineered against HCC with HBV integration in collaboration with Lion TCR Pte Ltd.
Cl A/Prof Goh Bee Tin is Head and Senior Consultant in the Department of Oral and Maxillofacial Surgery (OMS), Research Director and Deputy Director (Research and Education) at the National Dental Centre of Singapore (NDCS)Education. Her research interests include bone tissue engineering and mandibular reconstruction.
Prof. Jan is interested in how sensory processing interpret auditory inputs to the brain are transformed to underpin subjective perceptual qualities of sound such as pitch, timbre and sound source location, and how the brain learns to adapt to the statistical structure of the sounds in our environment to form efficient neural representations of sound and to support auditory scene analysis.
Prof. Hyeon- Ae Jeon is a principal investigator of Partner Group of the Max Planck Institute for Human Cognitive and Brain Sciences at the Department for Brain and Cognitive Sciences, DGIST.
Assoc Prof Dr Loh Siew Yim is a senior lecturer at the faculty of Medicine in University of Malaya, Malaysia Her research interest is cancer survivorship, and behavioural medicine .
Dr Paul Cliff Simon Divis is the director of Malaria Research Centre at Universiti Malaysia Sarawak (UNIMAS).
Yoon-Kyoung Cho is currently a group leader in the Center for Soft and Living Matter at the Institute for Basic Science (IBS) and a full professor in the Department of Biomedical Engineering at Ulsan National Institute of Science and Technology (UNIST) in the Republic of Korea.
Prof Yow is the Associate Head of the Humanities, Arts and Social Sciences at Singapore University of Technology and Design (SUTD) and leads the SUTD Language and Social Cognition Lab where they look at how language impacts on our cognitive functioning and understanding of the social world. Her research focuses on exploring and studying patterns of dual language use, how language environment may influence how children perceive communicative cues and how technology influences the way we communicate, and how it can be harnessed in ways that can improve or slow down the decline of cognition and social cognition.
David Virshup, M.D., is Director of the Programme in Cancer and Stem Cell Biology (CSCB) and Professor at Duke-NUS Medical School and is jointly appointed as Professor of Pediatrics at Duke University in North Carolina.
Eric Finkelstein is a Professor of the Programme in Health Services & Systems Research and the Executive Director of the Lien Centre for Palliative Care at the Duke-NUS Medical School, Singapore. He also holds appointments at NUS School of Public Health and Duke University Global Health Institute.
My PhD research entitled "No harm done? The experiences of women who inject drugs accessing harm reduction in Indonesia" examines the role of social, political and economic impacts on women who use/inject drugs and the correlation with increase rates of HIV/HCV and incarceration.
I am engaged in the development of a new device for embryo evaluation which measures embryo oxygen consumption and a new medication for infertility. Recently, I focused on causative genes of disorders of sex development and searched pathogenic variants using a whole-genome reference panel constructed by Tohoku Medical Megabank Organization.
I am an Assistant Professor in Health Services Policy and Management at the University of South Carolina Arnold School of Public Health, US. As a health services researcher and a rural health advocate, I am driven to advance rural health equity via productive, insightful research collaborations. My work applies global and hyper-local perspectives (rural-urban, county-level, state-level variations) building statistical models to examine rural healthcare delivery on outcomes, access, and welfare of women.
Professor Linfa Wang is a Professor with the Emerging Infectious Diseases Programme at Duke-NUS Medical School, Singapore.
Associate Professor Sophia Archuleta is the Head and Senior Consultant of the Division of Infectious Diseases at the National University Hospital, Singapore.
Ms. Mira Adhikari is a nursing faculty member on Pokhara Nursing Campus, Institute of Medicine, Tribhuvan University, Nepal. She has a rich experience of over 15 years in this profession.
Mangala Gunatilake is a veterinarian and professor at the Department of Physiology, Faculty of Medicine, University of Colombo, Sri Lanka.
Dr. Mais Aljunaidy is an expert in women's mental health and an instructor at the Department of Psychology, Bilkent University, Turkey.
Dr Heo is currently a senior lecturer at the Department of Microbiology and Parasitology, Faculty of Medicine, Universiti Teknologi MARA, Malaysia.
Dr. Tazeen Jafar is a global health leader and expert with a focus on implementation research in hypertension, cardiovascular disease, and chronic kidney disease.
Prof. Wang Hongyan is the deputy programme director and principal investigator of the laboratory of Neural Stem Cell at Duke-NUS Medical School, Singapore.
Dr Ramli is a Professor at Department of Psychiatry, Kulliyyah of Medicine at the International Islamic University Malaysia (IIUM).
Ji-Won Lee is an assistant professor at the Faculty of Dental Medicine at Hokkaido University, Japan,
Tadahiro Iimura is a professor in the Faculty of Dental Medicine, the Division of Dental Medicine, the Department of Pathobiological Science, Hokkaido University, Japan
Giants in history
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