Professor Manabu Tokeshi

Manabu Tokeshi is a Professor at the Division of Applied Chemistry at Hokkaido University.

Professor Tokeshi is also a visiting Professor at Innovative Research Center for Preventive Medical Engineering, and Institute of Innovation for Future Society at Nagoya University. He is a board member of the Chemical & Biological Microsystem Society (CBMS) which oversees the International Conference on Miniaturized Systems for Chemical and Life Sciences (╬╝TAS). He has been serving as an Associate Editor of Lab on a Chip (Royal Society of Chemistry) and an editorial board member of four international journals.

He received his PhD degree from Kyushu University in 1997. After a research fellow of the Japan Society of Promotion of Science at The University of Tokyo, he worked at Kanagawa Academy of Science and Technology as a researcher (1998-1999), group subleader (1999-2003), and group leader (2003-2004). He also worked at the Institute of Microchemistry Technology Co. Ltd. as President (2004-2005) and at Nagoya University as an Associate Professor (2005-2011). In 2011, he visited Karolinska Institutet as a visiting researcher and joined the Hokkaido University as a Professor.

His honors include the Outstanding Researcher Award on Chemistry and Micro-Nano Systems from the Society for Chemistry and Micro-Nano Systems (2007), the Pioneers in Miniaturisation Prize from the Lab on a Chip/Corning Inc. (2007), the Masao Horiba Award from HORIBA, Ltd. (2011) and the Japan Society for Analytical Chemistry Award from the Japan Society for Analytical Chemistry (2018). He is a Fellow of Royal Society of Chemistry (FRSC).

 His research interests are in the development of micro- and nano-systems for chemical, biochemical, and clinical applications.

Selected publications

  1. M. Tokeshi, et al., Determination of Subyoctomole Amounts of Nonfluorescent Molecules Using a Thermal Lens Microscope: Subsingle-Molecule Determination, Analytical Chemistry, 73, 2112-2116 (2001).
  2. M. Tokeshi, et al., Continuous-Flow Chemical Processing on a Microchip by Combining Microunit Operations and a Multiphase Flow Network, Analytical Chemistry, 74, 1565-1571 (2002).
  3. M. Ikami, et al., Immuno-Pillar Chip: a New Platform for Rapid and Easy-to-Use Immunoassay, Lab on a Chip, 10, 3335-3340 (2010).
  4. O. Wakao, et al., Fluorescence Polarization Measurement System Using a Liquid Crystal Layer and an Image Sensor, Analytical Chemistry, 87, 9647-9652 (2015).
  5. T. Yasui, et al., Label-Free Detection of Real-Time DNA Amplification Using a Nanofluidic Diffraction Grating, Scientific Reports, 6, 31642 (2016).
  6. N. Kimura, et al., Development of the iLiNP Device: Fine Tuning the Lipid Nanoparticles Size within 10 nm for Drug Delivery, ACS Omega, 3, 5044-5061 (2018).
  7. T. Komatsu, et al., Paper-Based Device for the Facile Colorimetric Determination of Lithium Ions in Human Whole Blood, ACS Sensors, 5, 1287-1294 (2020).