Bacteria, fungi and viruses normally live within the mouth, many of which are beneficial, while some can cause disease. The maintenance of a healthy balance of microorganisms in the mouth helps protect against infections. However, many approaches for treating diseases, like oral thrush, involve using compounds that disrupt the microbial balance (Fig. 1).
A collaborative effort between the Cluster of Cancer Research Initiative IIUM (COCRII), at the International Islamic University Malaysia (IIUM) and NFA Technologies Sdn. Bhd. successfully developed a new oral care product that promotes the growth of healthy bacteria in the mouth. The ultimate aim is to make a mouthwash that balances the oral microbiome (Fig. 2).
The product, called Micro-OroSYN, incorporates an advanced micro-encapsulation technique for the slow release of its active compounds.
A balanced microbiome can prevent oral diseases including oral candidiasis, dental caries and halitosis (Fig. 3). A recent study has also shown that a balanced oral microbiome can reduce the severity of covid-19 infection, indicating the relevance of the product. The advance micro-encapsulation technique allows the slow release of the active compounds, which increases the sensitivity of the product.
The researchers hope Micro-OroSYN, which uses halal ingredients, will impact clinical medicine and disease management in Malaysia.It has won several awards, such as Kuantan Research Day 2019, the Malaysia-Croatia Technology Exchange 2020 and Malaysia Technology Expo 2020 and 2021.
The project was sponsored by the Ministry of Higher Education Malaysia:
(Grant no: PRGS/1/2020/SKK/08/UIAM/02/1).
For more information, please contact:
- Assistant Professor Ts Dr Mohd Hafiz Arzmi: [email protected]
- Ms Nurul Alia Risma Rismayuddin: [email protected]
- Assistant Professor Dr. Awis Sukarni Mohmad Sabere: [email protected]
- Assistant Professor Dr. Abd Almonem Doolaanea: [email protected]
- Assistant Prof Dr Ahmad Faisal Ismail: [email protected]