Chemistry

Moving parts in mechanical come into regular contact, leading to wear and tear. Now, researchers at Tohoku University have developed a contact control system, driven by artificial intelligence, to greatly reduce contact between damaged parts.

Researchers at Kanazawa University report in Nano Letters the discovery of a biomolecular dynamical process likely relevant to gene expression. The process, revealed by means of high-speed atomic force microscopy, involves DNA and its packaging molecules.

A collaborative research group from Tohoku University and the Toyohashi University of Technology has invented a new and efficient method to create metallic plasmas from solid metals under a strong magnetic field in a microwave resonator.

Scientists from Oil Crops Research Institute (OCRI) of Chinese Academy of Agricultural Sciences (CAAS), Anhui Agricultural University (Anhui, China), Newcastle University in Singapore, and Huizhou Comvikin Biotechnology Co., Ltd (Guangdong, China) have developed a green and efficient approach to synthesize highly liposoluble and antioxidant L-ascorbyl esters by immobilized lipases.

Researchers from Osaka Metropolitan University have developed principles and technologies of nanofluidic devices to freely manipulate nanomaterials, biomaterials, and molecules at the single-molecule level using fundamental technologies such as nanofluidic processing, functional integration, and fluidic control and measurement, which has pioneered the way to integrate various fields under nanofluidics.

Researchers at Kanazawa University report in Angewandte Chemie International Edition how the formation and deformation speed of interlocked molecular structures called rotaxanes can be tuned — a discovery that may lead to an enhanced functionality of rotaxanes as building blocks for molecular machines.

Tree rings forecast extreme weather in central Asia, Squid 🦑and chemistry make versatile hydrogels, James Webb telescope reveals the earliest galaxies & Reducing negative effects of screen time. Read all in the latest Editor's Choice. Plus our latest journalist resource "Experts for Media: Antimicrobial Resistance "🦠.

Amide bonds are important functional groups in medicinal chemistry and account for roughly 16% of all reactions performed in drug-discovery research. Some amide bond reactions using pharmaceutically important nitrogen-containing heterocyclic compounds, such as indole, carbazole and pyrrole, rather than amines are not efficient using conventional production methods. In a recent study, a team of leading chemists developed a novel one-pot reaction to efficiently form amide bonds using low-reactivity, nitrogen-containing heterocyclic compounds and carboxylic acid without special equipment or heat.

- Elastic Triboelectric Tactile Sensor Development Using Graphene Electrode Unaffected by Elasticity - Published in 'Nano Energy' as a Technology to Produce Precise Sensors by Supplementing the Output Change Problem of Sensors Deformed by Human Activity

Hokkaido University researchers have developed a novel method to design and develop peptide antibiotics in large numbers, which will prove critical to controlling antibiotic resistance.

Two catalysts working in tandem enable inexpensive formate salts to perform difficult dearomative reactions, giving products potentially useful for drug development.

Researchers from Osaka University expanded the synthetic toolkit for preparing valuable chemical precursors from renewable feedstocks. They used microwave irradiation to dramatically improve the selectivity of the formose reaction, forming a simple six- and seven-carbon mixture that can be readily purified. These findings will help the chemicals industry minimize the use of fossil resources and improve the sustainability of manufacturing processes.

Traditional hydrogen peroxide production is energy and emission intensive, and so scientists have sought to synthesize it electrochemically. But tailoring the cobalt-nitrogen-carbon (Co-N-C) catalyst has been challenging. Using a theoretical prediction, which was then experimentally verified, an international research group has designed a Co-N-C catalyst that alleviates this problem.

Researchers used a chemical synthesis robot and computationally cost effective A.I. model to successfully predict and validate highly selective catalysts.

Researchers from Osaka University have used single carbon atom doping to form four chemical bonds in one step. Gamma-lactams (cyclic molecules that are common in antibiotics) were easily synthetically accessible from alpha, beta-unsaturated amides (an important molecule in cancer progression). The team chemically modified an anti-seizure medication in 96% yield, highlighting the work's utility to otherwise synthetically complex aspects of pharmaceutical development. The results of this work could become foundational to drug discovery and development.

Researchers from Osaka University have shown that a system known as the GET pathway is essential for efficient mitophagy, the process by which mitochondria are removed from cells. The GET pathway targets a protein assembly called the Ppg1–Far complex, which inhibits mitophagy, to the membrane of a part of the cell called the endoplasmic reticulum. When the GET pathway is defective, this complex instead becomes targeted to mitochondria, where it acts to suppress mitophagy.

Everyday electronics, such as our phones, employ surface acoustic wave devices for frequency filtering and sensing. But this consumes a lot of energy, serving as a drain on battery life. Now, a team of researchers has developed a new acoustic waveguide based on the mathematical concept of topology, which will help alleviate this problem.

Osaka Metropolitan University scientists have succeeded in synthesizing fumaric acid, a raw material for plastics, from CO2 powered by solar energy—for the first time. Typically, fumaric acid is synthesized from petroleum as a raw material to make polybutylene succinate, a biodegradable plastic, but this research shows that it can be synthesized from CO2 and biomass-derived compounds using renewable energy.

A research group, at the Osaka Metropolitan University Graduate School of Engineering, has succeeded in measuring spin transport in a thin film of αNPD molecules—a material well-known in organic light emitting diodes—at room temperature. They found that this thin molecular film has a spin diffusion length of approximately 62 nm, a length that could have practical applications in developing spintronics technology. In addition, while electricity has been used to control spin transport in the past, the thin molecular film used in this study is photoconductive, allowing spin transport control using visible light.

The natural abilities of squid tissues and the creativity of chemists combine to take hydrogel research in new directions.

Controlling a material’s thermal conductivity can help insulate our homes, improve the performance of electronic devices, conserve power consumption in cars, and generate greater power efficiency. Now, a group of researchers has unveiled a novel mechanism that leads to further suppression of thermal conductivity in thermoelectric materials, something that will help develop new guidelines for producing high-performance thermoelectric materials.

Magnesium hydride has long been touted for its potential to store large amounts of hydrogen, something essential if hydrogen is to play a role in powering a sustainable future. Yet, sluggish dehydrogenation kinetics and the high temperature required to decompose and produce hydrogen from the material have stymied its use. Now, researchers have identified why this is so, paving the way for future design guidelines and widespread commercial use.

A research group at Osaka Metropolitan University has succeeded in significantly reducing the measurement time of a glass standard sample by applying Bayesian estimation to X-ray fluorescence analysis. The ability to perform rapid non-contact elemental analysis in a nondestructive manner could lead to the widespread use of this technique in many fields, including the analysis of moving industrial products and waste materials while being carried on conveyor belts.

- DGIST Department of Energy Science and Engineering Professor Lee Jong-won's team developed oxide-based solid electrolyte technology with enhanced atmospheric stability - Anticipating the development of high-performance/high-safety all-solid-state batteries... Published in ‘Energy Storage Materials’

An international team of researchers has studied the heterostructures of layered antiferromagnets, painting a better picture of what happens when two different magnetic orders are combined.

There is a small area on the electromagnetic spectrum occupied by terahertz waves, where conventional electronic devices struggle to operate. Still, engineering devices that can take advantage of terahertz waves are crucial for the development of future wireless technology such as 6G and 7G. Using a graphene transistor, a research team has successfully detected terahertz waves with a fast response and high sensitivity at room temperature.

Understanding how bats tolerate viral infections, Material separates water from...water, The virtual sense of touch polished to next level and COVID-19 negatively impacted early-careers and female researchers. Read all in the December's Editor's Choice.

- Time Energy Solution Co., Ltd. develops a general consumer-friendly hydrogen fuel generator (Eco-Friendly Hydrogen Fuel Cell Generator) - Wins CES 2023 Award for Innovation in ‘Sustainability, Eco Design & Smart Energy’ with ‘Eco-friendly Hydrogen Fuel Cell Generator’

- DGIST Professor Lee Hong-Kyung's joint research team develops convection-induced new concept electrolyte through magnetic nanoparticles, dramatically improving the lifespan of next-generation lithium metal batteries - Recognized for its excellence, selected as the cover study in the prestigious international journal ‘Advanced Functional Materials’

A research group at Osaka Metropolitan University has discovered that 2,5-distyrylpyrazine (DSP) crystals undergo a unique photoreaction. Normally, photoreactive color changes proceed uniformly throughout photomechanical molecular crystals, so that all parts of each crystal change color at the same time. However, when light shines evenly on a DSP crystal, the photoreaction propagates from edge to center, deviating from conventional photochemistry models. The group found that this phenomenon was caused by a surface effect and a cooperative effect, which make reactivity extremely high for molecules at the crystal’s edge and those adjacent to molecules that have already changed color.