Biology Computational biology
News
13 Jan 2026
Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, in collaboration with Osaka University and the National Institutes for Quantum Science and Technology, have uncovered a previously unknown mechanism behind the activation of the Met receptor—a key player in tissue regeneration and cancer progression. Their findings reveal that HGF binding to the membrane-distal domain of Met promotes dimerization at the membrane-proximal domain, which subsequently triggers receptor activation.
23 Oct 2025
A collaboration team of researchers from the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, the Institute of Transformative Bio-Molecules (WPI-ITbM), Graduate School of Science at Nagoya University, and the RIKEN Center for Computational Science (R-CCS) reports in ACS Nano an integrative modeling workflow to understand with atomistic precision biomolecular dynamics from high-speed atomic force microscopy experiments.
18 Jun 2025
Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University observe and model how the enzyme ADAR1 interacts with double-stranded RNA, which may be useful for future cancer treatment strategies.
13 Mar 2025
Gene mutations in acute myeloid leukemia (AML) cells can guide treatment options, and machine learning can rapidly guess the existence of gene mutations based on images of leukemia cells.
28 Feb 2024
A new user-friendly tool helps researchers explore how gene activity is influenced by chemical modifications, providing insights into disease and paths to new treatments.
13 Dec 2023
Researchers at Kanazawa University report in Frontiers in Molecular Biosciences a computational method to predict the placement of proteins on AFM substrates based on electrostatic interactions.
23 Oct 2023
Risk-averse on/off-target assessment for CRISPR editing without reference genome
06 Jul 2022
Atomic force microscopy (AFM) allows to visualize the dynamics of single biomolecules during their functional activity. All observations are, however, restricted to regions accessible by a fairly big probing tip during scanning. Hence, AFM images only the biomolecular surface with limited spatial resolution, missing important information required for a detailed understanding of the observed phenomena.
29 Jun 2022
Researchers at Kanazawa University report in Biophysics and Physicobiology how to optimize high-speed atomic force microscopy experiments on live cell membranes, so that moving objects like molecules can be properly followed from frame to frame.
02 Sep 2021
Researchers at Kanazawa University report in Proceedings of the National Academy of Sciences how a protein molecular motor can chop off a piece of cell membrane. The constrict-and-cut mechanism resembles that of a ratchet motor, and is of importance in processes mediating the entry of particles into cells.
31 May 2021
High-resolution genome structural analyses combined with large-scale simulations show the arrangements of the genome’s spool-like structures affecting gene expression.
07 Apr 2021
New national body established to further research insights, improve patient outcomes and create new economic opportunities for the biomedical technology industry.
06 Feb 2020
A global research collaboration, led by world class institutions in Singapore, the UK and the USA, has developed the most detailed catalogue of mutational fingerprints found in most types of cancers that could help clarify their developmental history and lead to new prevention and treatment strategies.
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Researchers
Dr Yap is currently a Senior Lecturer and Program Director of Medical Bioscience at Monash University Malaysia. She is dedicated to toxin pharmacology and toxicology research. She has strong background in biomolecular modelling, proteomics, immunological and molecular pharmacology of bioactive toxins. She leads the Toxin Pharmacology Research Group. Her research group now focuses on molecular mechanisms of cytotoxin with the ultimate goal of developing next-generation biotherapeutics. Her research works have been featured in prominent media outlets, including the International Snakebite Awareness Day campaign. Besides active in research, she is also an education innovator who adopts various active learning strategies with technology. She teaches undergraduate units with an emphasis on student-cantered learning using the andragogy approach. Dr Michelle enjoys promoting STEM education to the public. She has organized and hosted several workshops and forums to advance the disciplines in medical sciences through research and education.
Dr. Sonia Chotani is a computational biologist working in the area of small open reading frames and RNA translation in human diseases.
Dr Owen Rackham is an expert in the development of computational approaches for cell reprogramming and disease-gene association.
Dr. Mamta Agrawal
BSc. (Maths, Physics, Chemistry), MSc. (Mathematics),
DCA (Diploma in computer applications)
MCA (Masters in computer applications)
PHD (Mathematics and Computational Biology)
POST DOC (Mathematics and Computational Biology)
completed two research projects: 1. WOS-A (DST New Delhi) 2. Indo-Austria research Projuect (DST-BMWF)
Visited Abrod four countries Thiland, South Korea, Austria, Nepal
Paper Pulication-18
ChpterPublication-1
Book Publication-1
Patent- going on
Professor Ken's current research mainly focuses on the causes and treatments of neurodegenerative diseases. His lab has developed a nanomaterial-based technology for harvesting autologous neural stem cells from the brain of living subjects.
Giants in history
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