Chemistry Molecular biology

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Figure. A novel electrochemical biosensor for the detection of ADAR1 in cells is expected to be useful in cancer prognosis.
10 Jun 2024
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University report in Biosensors and Bioelectronics: X a novel approach for detecting a particular biomolecule associated with several diseases. The results show good sensitivity and selectivity, and may lead to the development of a low-cost, rapid detection device useful in cancer prognosis.
Zinc Finger Nucleases
14 May 2024
Genome editing is making inroads into biomedical research and medicine. By employing biomolecule modeling tools, a Japanese research team is accelerating the pace and cutting the cost of zinc finger nuclease (ZFN) technology, a primary gene editing tool.
Depiction of europium complexes changing structure upon interacting with a tumor cell. (Mengfei Wang, et al. Scientific Reports. January 22, 2024)
22 Jan 2024
A water-soluble, luminescent europium complex enables evaluation of malignancy grade in model glioma tumor cells.
15 May 2023
Researchers at Kanazawa University report in the Proceedings of the National Academy of Sciences of the United States of America (PNAS) high-speed atomic force microscopy experiments that show how ligands associated with stimulating and suppressing activation of the TRPV1 protein increase and decrease the molecule’s structural variations. The observations provide insights into how these heat- and chilli-sensing proteins function.
Methods developed for measuring reactive polysulfides in vegetables
10 Mar 2023
Osaka Metropolitan University scientists successfully quantified the total reactive polysulfide content of 22 different types of vegetables, including onions and garlic. They also revealed that reactive polysulfides are not only found in the leek genus (Allium), such as onions and garlic but also in the cruciferous family of vegetables (Brassicaceae), such as broccoli and cabbage.
 IMAGE
14 Jul 2021
Researchers have found a way to enhance radiation therapy using novel iodine nanoparticles.
The anomalies and criticality of liquid water
29 Oct 2020
Scientists at The University of Tokyo use a two-state model based on the formation of tetrahedral structures to explain water’s anomalous properties and the surprising liquid–liquid transition of water.
Fig. 1
07 Sep 2018
Researchers at Nagoya University, Japan, have developed a spontaneous polymer network synthesis that allowed for the preparation of gels containing narrow molecular weight distribution polymers. The gel networks showed swelling properties that were responsive to temperature and solvent concentration.
Fig. 1 An “eat me” signal makes severed neurons regenerate
27 Aug 2018
Researchers at Nagoya University have identified the series of molecules involved in the regeneration of damaged nerves in roundworm, showing that it largely overlaps with the signals used by the intrinsic removal system to take up and process dying cells.

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