Peer Reviewed

- DGIST Joint Team of Professors Kim Hoe-joon and Hong Seon-ki developed high-efficiency piezoelectric energy harvesting technology using materials harmless to humans - Attachable to body, generates energy and diagnoses exercise posture... Published in the November issue of ‘Nano Energy’

- DGIST Professor Jin Kyong-hwan’s research team develops algorithm that has 3dB higher resolution than existing algorithms and compatible with various warping domains - Published in ‘ECCV’, an academic journal with global authority in the field of vision technology

Researchers at The University of Tokyo develop a simple but effective method of bonding polymers with galvanized steel, a material ubiquitous in the automobile industry, to cheaply and easily create a lightweight and durable product.

A research group at Osaka Metropolitan University has discovered that 2,5-distyrylpyrazine (DSP) crystals undergo a unique photoreaction. Normally, photoreactive color changes proceed uniformly throughout photomechanical molecular crystals, so that all parts of each crystal change color at the same time. However, when light shines evenly on a DSP crystal, the photoreaction propagates from edge to center, deviating from conventional photochemistry models. The group found that this phenomenon was caused by a surface effect and a cooperative effect, which make reactivity extremely high for molecules at the crystal’s edge and those adjacent to molecules that have already changed color.

A study by Osaka University has shown that the prevalence of non-communicable diseases, which included hypertension, hyperlipidemia, diabetes, and mental disorders, increased after the Fukushima disaster and the COVID-19 outbreak. These findings emphasize the importance of improving post-disaster health promotion strategies and recommendations.

Researchers at The University of Tokyo show how including the effects of the surrounding water during the aggregation of charged particles can improve the accuracy of simulations, which may help elucidate biological self-assembly

Revelations about the mechanisms of two key proteins which maintain the asymmetric distribution of cholesterol within the cell membrane could help understand and treat diseases linked to its imbalance

Scientists investigate how genes in some insects can influence one another to change their expression depending on environmental conditions.

A new coating for tiny packages called liposomes could allow them to carry vaccines and drugs into and around the body more safely.

Silencing the gene, called WWP2, in patients in the early stages of cardiomyopathy could delay progression to heart failure by controlling immune cell infiltration and activation, and halting the formation of excessive scar tissue, preclinical data suggest.

Greetings from JHSSR, and hello from sodden Malaysia, Horizon is proud to announce the highly acclaimed publication of the latest issue of 2022, Vol.4, Issue 2 (Dec. 2022). The issue is now live at the Journal’s webpage. You may explore our range of contributions within this Issue. Explore this issue, click the links below.

Quinine and various drugs based on its chemical structure have been used to treat malaria for centuries. But parasites resistant to antimalarial drugs are becoming apparent. To pave the way for future medicine development, an efficient way to synthesize quinine was needed. And now a research team from Tohoku University has achieved just that.

Reef corals provide an accurate, high-resolution record of the influence of the El Niño Southern Oscillation on rainfall, flooding and droughts in the Mekong River Delta, Vietnam.

Magnetic nozzle plasma thrusters are thought of as the future of space travel. But one problem has hampered their development – plasma detachment. A recent study has shown that spontaneously excited plasma waves help magnetic nozzles overcome the plasma detachment problem, a rare instance of plasma instabilities having a positive effect on engineering.

Studying an atomic clock on-board a spacecraft inside the orbit of Mercury and very near to the Sun could be the trick to uncovering the nature of dark matter.

Tin sulfide (SnS) solar cells have shown immense promise in the rush to develop more environmentally friendly thin-film solar cells. Yet for years SnS solar cells have struggled to achieve a high conversion efficiency. To overcome this, a SnS interface exhibiting large band bending was necessary, something a research group has recently achieved.

Machine learning and robotic process automation combine to speed up and simplify a process used to determine crystal structures.

Precise control of quantum systems, such as quantum computers, is of great importance for modern quantum science. One way this has been done is via spin echoes. A research group has discovered a new type of echo, labelling them “energy-band echoes.”

Automated reaction path search method predicts accurate stereochemistry of pericyclic reactions using only target molecule structure.

Osaka Metropolitan University researchers introduced seven proteins, thought to let bacteria swim by switching the direction that their helical bodies spiral, into a strain of synthetic bacterium with minimal genetic information. As a result, they confirmed that the synthetic bacterium named syn3, which is normally spherical, formed a helix that could swim by spiraling. Further investigation revealed that only two of these newly added proteins were required to make syn3 capable of minimal swimming. This swimming synthetic bacterium can be said to be the smallest mobile lifeform genetically, as it contains the fewest number of genes.

Some mixed halogenated dioxins are more toxic than TCDD

Using a quantum computer, Osaka Metropolitan University researchers utilized quantum logic circuits to directly calculate, in a single calculation, the energy difference between two molecular geometries. The developed method was then applied to execute the molecular geometry optimization of typical molecular systems. On a classical computer, calculations based on the finite difference method require at least two evaluations of the energy for one-dimensional systems, but previous research has shown that a quantum computer can be used to calculate the energy derivatives based on this method in a single calculation. However, quantum circuits relevant to quantum algorithms capable of performing the energy derivative calculations had not been implemented. The research group has successfully created a quantum circuit to calculate the energy derivatives by modifying the quantum circuit used in the previously developed quantum phase difference estimation algorithm.

The Sox9 gene is upregulated in the absence of sex-determining Y chromosome and Sry gene in Amami spiny rat.

A Hong Kong Baptist University (HKBU) collaborative research team has synthesised a nanoparticle named TRZD that can perform the dual function of diagnosing and treating glioma in the brain. It emits persistent luminescence for the diagnostic imaging of glioma tissues in vivo and inhibits the growth of tumour cells by aiding the targeted delivery of chemotherapy drugs. The nanoparticle offers hope for the early diagnosis and treatment of glioma, especially cerebellar glioma, which is even harder to detect and cure with existing methods.

We don’t know much about the Earth’s inner core because recreating its conditions in a laboratory setting remains fraught with difficulties. Based on tracking seismic waves, scientists theorize that the area in and around the core comprises mostly of iron. But the values extracted from these indicators differ from how pure iron typically behaves. Now, a collaborative research group has succeeded, for the first time, in measuring the speed of sound of pure iron under pressures similar to the Earth’s inner core boundary.

Most metal and alloys possess a high elastic strain rate at the micro level. But this changes when they are in their bulk shape, as they are for everyday engineering applications. Now, a research group has developed a bulk copper-based alloy boasting the largest tensile elastic strain at room temperature to date.

Researchers at Tohoku University have shown that astrocytes in the mouse brain exhibit an acid response with intensified epileptic seizures. The astrocytes’ acid response could lead to the amplification of excitatory neuronal signals and be the underlying drive for generating plasticity for epileptogenesis.

Researchers led by Osaka University identified plasma proteins associated with critical pathogenesis in COVID-19. Using a novel blood proteomics method, the researchers evaluated two discovery cohorts and one validation cohort of patients with COVID-19 and healthy volunteers. Cell adhesion proteins WFDC2, GDF15, CHI3L1, and KRT19 were shown to be associated with disease severity in patients with COVID-19, and may serve as potential targets for therapies to treat COVID-19 infection.

A research group at the Osaka Metropolitan University Graduate School of Science has revealed a new system that allows them to control the behavior of the nematode worm Caenorhabditis elegans, using two different animal opsins, a type of light-sensitive protein. The first opsin was expressed in the worms’ sensory cells responsible for triggering avoidance behavior, making the worms move. This opsin was found to be approximately 7,000 times more sensitive to white light than the commonly used optogenetic protein channelrhodopsin-2. Likewise, a UV-sensitive opsin was expressed in the worms’ motor neurons, causing the worms to stop when exposed to UV light and start moving again when exposed to green light. Both opsins tested can be switched on and off repeatedly without breaking down, making them robust tools for future research, including the field of drug discovery.

A research team at Osaka Metropolitan University has developed a microelectromechanical system (MEMS) piezoelectric vibration energy harvester, which is only about 2 cm in diameter with a U-shaped metal vibration amplification component. The device allows for an increase of approximately 90 times in the power generation performance from impulsive vibration. Since the power generation performance can be improved without increasing the device size, the technology is expected to generate power to drive small wearable devices from non-steady vibrations, such as walking motion.